From organophosphate poisoning to diabetes mellitus: The incretin effect

Medical Hypotheses

Volumn 91, Issue , 2016, Pages 53-55

  Rathish, D ^a   Agampodi, S B ^a   Jayasumana, M A C S ^a   Siribaddana, S H ^a  

^a UNIVERSITY OF COLOMBO   (Sri Lanka)

Author keywords

Acetylcholine; Atropine; Glucagon Like Peptide 1; Glucose homeostasis; Incretins; Organophosphate; Type 2 diabetes mellitus

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CARBAMIC ACID; GLUCAGON LIKE PEPTIDE 1; INCRETIN; MUSCARINIC RECEPTOR; ORGANOPHOSPHATE PESTICIDE; ATROPINE; GLUCOSE; ORGANOPHOSPHATE;

ARTICLE; DIABETES MELLITUS; GLUCOSE HOMEOSTASIS; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; MORTALITY; NERVE STIMULATION; NEUROENDOCRINE SYSTEM; NON INSULIN DEPENDENT DIABETES MELLITUS; ORGANOPHOSPHATE POISONING; ANIMAL; DIABETES MELLITUS, TYPE 2; ENDOCRINE SYSTEM; HOMEOSTASIS; METABOLISM; THEORETICAL MODEL; TREATMENT OUTCOME;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ANIMALS; ATROPINE; DIABETES MELLITUS, TYPE 2; ENDOCRINE SYSTEM; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; HOMEOSTASIS; HUMANS; INCRETINS; MODELS, THEORETICAL; ORGANOPHOSPHATE POISONING; ORGANOPHOSPHATES; TREATMENT OUTCOME;

EID: 84962860996     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2016.04.002     Document Type: Article

References (31)

1. International Diabetes Federation IDF Diabetes 2015, International Diabetes Federation, Brussels, Belgium, http://www.diabetesatlas.org. 7 ed.
2. Chan J.C., Malik V., Jia W., Kadowaki T., Yajnik C.S., Yoon K.H.H.F. Diabetes in Asia. Jama 2009, 301:2129-2140.
3. Katulanda P., Rathnapala D., Sheriff R., Matthews D. Province and ethnic specific prevalence of diabetes among Sri Lankan adults. Sri Lanka J Diabetes Endocrinol Metab 2012, 1:2-7.
4. Holst J.J., Knop F.K., Vilsbøll T., Krarup T., Madsbad S. Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes. Diabetes Care 2011, 34(Suppl 2):S251-S257.
5. Nauck M., Stöckmann F., Ebert R., Creutzfeldt W. Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 1986, 29:46-52.
6. Gifford R., Siribaddana S., Forbes S., Eddleston M. Endocrine-disrupting chemicals and the diabetes epidemic in countries in the WHO South-East Asia region. Lancet Diabetes Endocrinol 2015, 3:925-927.
7. Elrick H., Stimmler L., Hlad C.J., Arai Y. Plasma insulin response to oral and intravenous glucose administration. J Clin Endocrinol Metab 1964, 24:1076-1082.
8. Perley M.J., Kipnis D.M. Plasma insulin responses to oral and intravenous glucose: studies in normal and diabetic subjects. J Clin Invest 1967, 46:1954-1962.
9. Prins J.B. Incretin mimetics and enhancers: mechanisms of action. Aust Prescr 2008, 31:102-104.
10. Seino Y., Fukushima M., Yabe D. GIP and GLP-1, the two incretin hormones: Similarities and differences. J Diabetes Investig 2010, 1:8-23.
11. Singh A.K. Incretin response in Asian type 2 diabetes: are Indians different?. Indian J Endocrinol Metab 2015, 19:30-38.
12. Kim Y.G., Hahn S., Oh T.J., Kwak S.H., Park K.S., Cho Y.M. Differences in the glucose-lowering efficacy of dipeptidyl peptidase-4 inhibitors between Asians and non-Asians: a systematic review and meta-analysis. Diabetologia 2013, 56:696-708.
13. Anini Y., Brubaker P.L. Muscarinic receptors control glucagon-like peptide 1 secretion by human endocrine L cells. Endocrinology 2003, 144:3244-3250.
14. Anini Y., Hansotia T., Brubaker P.L. Muscarinic receptors control postprandial release of glucagon-like peptide-1: In vivo and in vitro studies in rats. Endocrinology 2002, 143:2420-2426.
15. Balks H.J., Holst J.J., Von zur Mühlen A., Brabant G. Rapid oscillations in plasma glucagon-like peptide-1 (GLP-1) in humans: cholinergic control of GLP-1 secretion via muscarinic receptors. J Clin Endocrinol Metab 1997, 82:786-790.
16. Rocca A.S., Brubaker P.L. Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion. Endocrinology 1999, 140:1687-1694.
17. Lasram M.M., Dhouib I.B., Annabi A., El Fazaa S., Gharbi N. A review on the molecular mechanisms involved in insulin resistance induced by organophosphorus pesticides. Toxicology 2014, 322:1-13.
18. Karami-Mohajeri S., Abdollahi M. Toxic influence of organophosphate, carbamate, and organochlorine pesticides on cellular metabolism of lipids, proteins, and carbohydrates: a systematic review. Hum Exp Toxicol 2011, 30:1119-1140.
19. Thayer K.A., Heindel J.J., Bucher J.R., Gallo M.A. Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review. Environ Health Perspect 2012, 120:779-789.
20. Hectors T.L.M., Vanparys C., van der Ven K., Martens G.A., Jorens P.G., Van Gaal L.F., et al. Environmental pollutants and type 2 diabetes: a review of mechanisms that can disrupt beta cell function. Diabetologia 2011, 54:1273-1290.
21. Montgomery M.P., Kamel F., Saldana T.M., Alavanja M.C.R., Sandler D.P. Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003. Am J Epidemiol 2008, 167:1235-1246.
22. Joshi A.K.R., Rajini P.S. Organophosphorus insecticides and glucose homeostasis. Insecticides - pest engineering 2012, vol. 1:65-79. InTech.
23. McNab C. WHO | pesticides are a leading suicide method 2006, WHO Communications, http://www.who.int/mediacentre/news/notes/2006/np24/en/.
24. Thomas S.H.L., White J. Organophosphorus insecticides and nerve agents. Davidson's principles and practice of medicine 2014, 220. Elsevier Limited. 22nd ed. B.R. Walker, N.R. Colledge, S.H. Ralston, I.D. Penman (Eds.).
25. Senarathna L., Jayamanna S.F., Kelly P.J., Buckley N.A., Dibley M.J., Dawson A.H. Changing epidemiologic patterns of deliberate self poisoning in a rural district of Sri Lanka. BMC Public Health 2012, 12:593.
26. Fukuto T.R. Mechanism of action of organophosphorus and carbamate insecticides. Environ Health Perspect 1990, 87:245-254.
27. WikiTox - Organophosphates, . http://curriculum.toxicology.wikispaces.net/2.2.7.4.5+Organophosphates.
28. Duttaroy A., Zimliki C.L., Gautam D., Cui Y., Mears D., Wess J. Muscarinic stimulation of pancreatic insulin and glucagon release is abolished in m3 muscarinic acetylcholine receptor-deficient mice. Diabetes 2004, 53:1714-1720.
29. Swaminathan K., Sundaram M., Prakash P., Subbiah S. Diabetic ketoacidosis: an uncommon manifestation of pesticide poisoning. Diabetes Care 2013, 36:e4.
30. Kumar K.J., Nayak N. Organophosphorus poisoning presenting as diabetic ketoacidosis. Indian Pediatr 2011, 48:74.
31. Akyildiz B.N., Kondolot M., Kurtoğlu S., Akin L. Organophosphate intoxication presenting as diabetic keto-acidosis. Ann Trop Paediatr 2009, 29:155-158.