Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival

Oncotarget

Volumn 7, Issue 11, 2016, Pages 12254-12266

  Saveljeva, Svetlana ^a   Cleary, Patricia ^a   Mnich, Katarzyna ^a   Ayo, Abiodun ^a   Pakos Zebrucka, Karolina ^a   Patterson, John B ^b   Logue, Susan E ^a   Samali, Afshin ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b MannKind Corporation   (United States)

Author keywords

Autophagy; Cell death; ER stress; SESTRIN 2; UPR

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MEMBRANE PROTEIN; PROTEIN IRE1; PROTEIN PERK; REGULATOR PROTEIN; SESTRIN 2; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; EIF2AK3 PROTEIN, HUMAN; ERN1 PROTEIN, HUMAN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; NUCLEAR PROTEIN; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; SESN2 PROTEIN, HUMAN; XBP1 PROTEIN, HUMAN;

ARTICLE; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; TRANSLATION REGULATION; UNFOLDED PROTEIN RESPONSE; BIOSYNTHESIS; GENETICS; HCT 116 CELL LINE; HUMAN; MCF-7 CELL LINE; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE; UPREGULATION;

CELL LINE, TUMOR; CELL SURVIVAL; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; HCT116 CELLS; HUMANS; MCF-7 CELLS; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; UP-REGULATION; X-BOX BINDING PROTEIN 1;

EID: 84962860348     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.7601     Document Type: Article

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