Genes encoding members of the JAK-STAT pathway or epigenetic regulators are recurrently mutated in T-cell prolymphocytic leukaemia

British Journal of Haematology

Volumn 173, Issue 2, 2016, Pages 265-273

  López, Cristina ^a   Bergmann, Anke K ^a   Paul, Ulrike ^a   Murga Penas, Eva M ^a   Nagel, Inga ^a   Betts, Matthew J ^b   Johansson, Patricia ^c,d   Ritgen, Matthias ^e   Baumann, Tycho ^f   Aymerich, Marta ^g   Jayne, Sandrine ^h   Russell, Robert B ^b   Campo, Elias ^g   Dyer, Martin Js ^h   Dürig, Jan ^c,i   Siebert, Reiner ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY HOSPITAL ESSEN   (Germany)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

^e UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^f HOSPITAL CLÍNIC   (Spain)

^g UNIVERSITY OF BARCELONA   (Spain)

^h UNIVERSITY OF LEICESTER   (United Kingdom)

ⁱ GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

JAK3; STAT5B; Epigenetic regulators; T cell lymphoma; T cell prolymphocytic leukaemia

Indexed keywords

JANUS KINASE 3; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STAT5B PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BCOR; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR TET2; UNCLASSIFIED DRUG; BCOR PROTEIN, HUMAN; GENETIC MARKER; JAK3 PROTEIN, HUMAN; ONCOPROTEIN; REPRESSOR PROTEIN; STAT5 PROTEIN; STAT5B PROTEIN, HUMAN; TUMOR MARKER;

ADULT; AGED; ARTICLE; CHROMOSOME ABERRATION; CLINICAL ARTICLE; COHORT ANALYSIS; CYTOGENETICS; FEMALE; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; JAK3 GENE; MALE; PRIORITY JOURNAL; PROLYMPHOCYTIC LEUKEMIA; RHOA GENE; STAT5B GENE; DNA MUTATIONAL ANALYSIS; GENETIC EPIGENESIS; GENETIC MARKER; GENETICS; MIDDLE AGED; MUTATION; PROCEDURES; RECURRENT DISEASE; SIGNAL TRANSDUCTION;

AGED; BIOMARKERS, TUMOR; COHORT STUDIES; DNA MUTATIONAL ANALYSIS; EPIGENESIS, GENETIC; FEMALE; GENETIC MARKERS; HUMANS; JANUS KINASE 3; LEUKEMIA, PROLYMPHOCYTIC, T-CELL; MALE; MIDDLE AGED; MUTATION; PROTO-ONCOGENE PROTEINS; RECURRENCE; REPRESSOR PROTEINS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR;

EID: 84962855605     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13952     Document Type: Article

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