메뉴 건너뛰기




Volumn 7, Issue 12, 2016, Pages 15047-15064

Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells

Author keywords

Endocannabinoids; FAAH inhibitors; Human lung cancer cells; Invasion; Metastasis

Indexed keywords

ANTIMETASTATIC AGENT; ARACHIDONOYL SEROTONIN; CANNABINOID 2 RECEPTOR; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; AMIDASE; ARACHIDONIC ACID DERIVATIVE; ARACHIDONOYLSEROTONIN; BENZAMIDE DERIVATIVE; CARBAMIC ACID DERIVATIVE; CYCLOHEXYL CARBAMIC ACID 3'-CARBAMOYLBIPHENYL-3-YL ESTER; FATTY-ACID AMIDE HYDROLASE; SEROTONIN; TIMP1 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84962838964     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.7592     Document Type: Article
Times cited : (55)

References (41)
  • 1
    • 84921602739 scopus 로고    scopus 로고
    • New insights into antimetastatic and antiangiogenic effects of cannabinoids
    • Ramer R, Hinz B. New insights into antimetastatic and antiangiogenic effects of cannabinoids. Int Rev Cell Mol Biol. 2015; 314:43-116.
    • (2015) Int Rev Cell Mol Biol , vol.314 , pp. 43-116
    • Ramer, R.1    Hinz, B.2
  • 4
    • 74549185125 scopus 로고    scopus 로고
    • FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels
    • Petrosino S, Di Marzo V. FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels. Curr Opin Investig Drugs. 2010; 11:51-62.
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 51-62
    • Petrosino, S.1    Di Marzo, V.2
  • 5
    • 0027180394 scopus 로고
    • Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist
    • Deutsch DG, Chin SA. Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. Biochem Pharmacol. 1993; 46:791-796.
    • (1993) Biochem Pharmacol , vol.46 , pp. 791-796
    • Deutsch, D.G.1    Chin, S.A.2
  • 7
    • 37149013708 scopus 로고    scopus 로고
    • A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
    • Blankman JL, Simon GM, Cravatt BF. A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. Chem Biol. 2007; 14:1347-1356.
    • (2007) Chem Biol , vol.14 , pp. 1347-1356
    • Blankman, J.L.1    Simon, G.M.2    Cravatt, B.F.3
  • 8
    • 4744354729 scopus 로고    scopus 로고
    • Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies
    • Mor M, Rivara S, Lodola A, Plazzi PV, Tarzia G, Duranti A, Tontini A, Piersanti G, Kathuria S, Piomelli D. Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies. J Med Chem. 2004; 47:4998-5008.
    • (2004) J Med Chem , vol.47 , pp. 4998-5008
    • Mor, M.1    Rivara, S.2    Lodola, A.3    Plazzi, P.V.4    Tarzia, G.5    Duranti, A.6    Tontini, A.7    Piersanti, G.8    Kathuria, S.9    Piomelli, D.10
  • 9
    • 27744466783 scopus 로고    scopus 로고
    • Mechanism of carbamate inactivation of FAAH: implications for the design of covalent inhibitors and in vivo functional probes for enzymes
    • Alexander JP, Cravatt BF. Mechanism of carbamate inactivation of FAAH: implications for the design of covalent inhibitors and in vivo functional probes for enzymes. Chem Biol. 2005; 12:1179-1187.
    • (2005) Chem Biol , vol.12 , pp. 1179-1187
    • Alexander, J.P.1    Cravatt, B.F.2
  • 13
    • 63849288849 scopus 로고    scopus 로고
    • Endocannabinoid modulation of scratching response in an acute allergenic model: a new prospective neural therapeutic target for pruritus
    • Schlosburg JE, Boger DL, Cravatt BF, Lichtman AH. Endocannabinoid modulation of scratching response in an acute allergenic model: a new prospective neural therapeutic target for pruritus. J Pharmacol Exp Ther. 2009; 329:314-323.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 314-323
    • Schlosburg, J.E.1    Boger, D.L.2    Cravatt, B.F.3    Lichtman, A.H.4
  • 15
    • 33947356978 scopus 로고    scopus 로고
    • The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport
    • Solinas M, Tanda G, Justinova Z, Wertheim CE, Yasar S, Piomelli D, Vadivel SK, Makriyannis A, Goldberg SR. The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. J Pharmacol Exp Ther. 2007; 321:370-380.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 370-380
    • Solinas, M.1    Tanda, G.2    Justinova, Z.3    Wertheim, C.E.4    Yasar, S.5    Piomelli, D.6    Vadivel, S.K.7    Makriyannis, A.8    Goldberg, S.R.9
  • 16
    • 9444280832 scopus 로고    scopus 로고
    • A new strategy to block tumor growth by inhibiting endocannabinoid inactivation
    • Bifulco M, Laezza C, Valenti M, Ligresti A, Portella G, Di Marzo V. A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. FASEB J. 2004; 18:1606-1608.
    • (2004) FASEB J , vol.18 , pp. 1606-1608
    • Bifulco, M.1    Laezza, C.2    Valenti, M.3    Ligresti, A.4    Portella, G.5    Di Marzo, V.6
  • 19
    • 84935104912 scopus 로고    scopus 로고
    • A simple method for simultaneous determination of N-arachidonoylethanolamine, N-oleoylethanolamine, N-palmitoylethanolamine and 2-arachidonoylglycerol in human cells
    • Ivanov I, Borchert P, Hinz B. A simple method for simultaneous determination of N-arachidonoylethanolamine, N-oleoylethanolamine, N-palmitoylethanolamine and 2-arachidonoylglycerol in human cells. Anal Bioanal Chem. 2015; 407:1781-1787.
    • (2015) Anal Bioanal Chem , vol.407 , pp. 1781-1787
    • Ivanov, I.1    Borchert, P.2    Hinz, B.3
  • 20
    • 77957369035 scopus 로고    scopus 로고
    • Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells
    • Ramer R, Rohde A, Merkord J, Rohde H, Hinz B. Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells. Pharm Res. 2010; 27:2162-2174.
    • (2010) Pharm Res , vol.27 , pp. 2162-2174
    • Ramer, R.1    Rohde, A.2    Merkord, J.3    Rohde, H.4    Hinz, B.5
  • 24
    • 0026717181 scopus 로고
    • Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in B16-F10 melanoma cells
    • Khokha R, Zimmer MJ, Graham CH, Lala PK, Waterhouse P. Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in B16-F10 melanoma cells. J Natl Cancer Inst. 1992; 84:1017-1022.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1017-1022
    • Khokha, R.1    Zimmer, M.J.2    Graham, C.H.3    Lala, P.K.4    Waterhouse, P.5
  • 25
    • 13144257729 scopus 로고    scopus 로고
    • Intestinal trefoil factor promotes invasion in non-tumorigenic Rat-2 fibroblast cell
    • Chan VY, Chan MW, Leung WK, Leung PS, Sung JJ, Chan FK. Intestinal trefoil factor promotes invasion in non-tumorigenic Rat-2 fibroblast cell. Regul Pept. 2005; 127:87-94.
    • (2005) Regul Pept , vol.127 , pp. 87-94
    • Chan, V.Y.1    Chan, M.W.2    Leung, W.K.3    Leung, P.S.4    Sung, J.J.5    Chan, F.K.6
  • 26
    • 38049185265 scopus 로고    scopus 로고
    • Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1
    • Ramer R, Hinz B. Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1. J Natl Cancer Inst. 2008; 100:59-69.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 59-69
    • Ramer, R.1    Hinz, B.2
  • 27
    • 77449127143 scopus 로고    scopus 로고
    • Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1
    • Ramer R, Merkord J, Rohde H, Hinz B. Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. Biochem Pharmacol. 2010; 79:955-966.
    • (2010) Biochem Pharmacol , vol.79 , pp. 955-966
    • Ramer, R.1    Merkord, J.2    Rohde, H.3    Hinz, B.4
  • 30
    • 84908355024 scopus 로고    scopus 로고
    • Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1
    • Haustein M, Ramer R, Linnebacher M, Manda K, Hinz B. Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1. Biochem Pharmacol. 2014; 92:312-325.
    • (2014) Biochem Pharmacol , vol.92 , pp. 312-325
    • Haustein, M.1    Ramer, R.2    Linnebacher, M.3    Manda, K.4    Hinz, B.5
  • 31
    • 84906790681 scopus 로고    scopus 로고
    • Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells
    • Ramer R, Fischer S, Haustein M, Manda K, Hinz B. Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells. Biochem Pharmacol. 2014; 91:202-216.
    • (2014) Biochem Pharmacol , vol.91 , pp. 202-216
    • Ramer, R.1    Fischer, S.2    Haustein, M.3    Manda, K.4    Hinz, B.5
  • 32
    • 84878016500 scopus 로고    scopus 로고
    • Reduced in vivo lung metastasis of a breast cancer cell line after treatment with Herceptin mAb conjugated to chemotherapeutic drugs
    • Garcia AG, Nedev H, Bijian K, Su J, Alaoui-Jamali MA, Saragovi HU. Reduced in vivo lung metastasis of a breast cancer cell line after treatment with Herceptin mAb conjugated to chemotherapeutic drugs. Oncogene 2013; 32:2527-2533.
    • (2013) Oncogene , vol.32 , pp. 2527-2533
    • Garcia, A.G.1    Nedev, H.2    Bijian, K.3    Su, J.4    Alaoui-Jamali, M.A.5    Saragovi, H.U.6
  • 33
    • 67650097012 scopus 로고    scopus 로고
    • Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo
    • Yamai H, Sawada N, Yoshida T, Seike J, Takizawa H, Kenzaki K, Miyoshi T, Kondo K, Bando Y, Onishi Y, Tangoku A. Triterpenes augment the inhibitory effects of anticancer drugs on growth of human esophageal carcinoma cells in vitro and suppress experimental metastasis in vivo. Int J Cancer. 2009; 125:952-960.
    • (2009) Int J Cancer , vol.125 , pp. 952-960
    • Yamai, H.1    Sawada, N.2    Yoshida, T.3    Seike, J.4    Takizawa, H.5    Kenzaki, K.6    Miyoshi, T.7    Kondo, K.8    Bando, Y.9    Onishi, Y.10    Tangoku, A.11
  • 34
    • 34548763142 scopus 로고    scopus 로고
    • Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model
    • Lee TK, Poon RT, Wo JY, Ma S, Guan XY, Myers JN, Altevogt P, Yuen AP. Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model. Cancer Res. 2007; 67:8800-8809.
    • (2007) Cancer Res , vol.67 , pp. 8800-8809
    • Lee, T.K.1    Poon, R.T.2    Wo, J.Y.3    Ma, S.4    Guan, X.Y.5    Myers, J.N.6    Altevogt, P.7    Yuen, A.P.8
  • 35
    • 33845740735 scopus 로고    scopus 로고
    • A novel anticancer effect of thalidomide: inhibition of intercellular adhesion molecule-1-mediated cell invasion and metastasis through suppression of nuclear factor-kappaB
    • Lin YC, Shun CT, Wu MS, Chen CC. A novel anticancer effect of thalidomide: inhibition of intercellular adhesion molecule-1-mediated cell invasion and metastasis through suppression of nuclear factor-kappaB. Clin Cancer Res. 2006; 12:7165-7173.
    • (2006) Clin Cancer Res , vol.12 , pp. 7165-7173
    • Lin, Y.C.1    Shun, C.T.2    Wu, M.S.3    Chen, C.C.4
  • 36
    • 84901194475 scopus 로고    scopus 로고
    • FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway
    • Ravi J, Sneh A, Shilo K, Nasser MW, Ganju RK. FAAH inhibition enhances anandamide mediated anti-tumorigenic effects in non-small cell lung cancer by downregulating the EGF/EGFR pathway. Oncotarget 2014; 5:2475-2486. doi: 10.18632/oncotarget.1723.
    • (2014) Oncotarget , vol.5 , pp. 2475-2486
    • Ravi, J.1    Sneh, A.2    Shilo, K.3    Nasser, M.W.4    Ganju, R.K.5
  • 37
    • 84858326797 scopus 로고    scopus 로고
    • The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action
    • Hamtiaux L, Masquelier J, Muccioli GG, Bouzin C, Feron O, Gallez B, Lambert DM. The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action. BMC Cancer. 2012; 12:92.
    • (2012) BMC Cancer , vol.12 , pp. 92
    • Hamtiaux, L.1    Masquelier, J.2    Muccioli, G.G.3    Bouzin, C.4    Feron, O.5    Gallez, B.6    Lambert, D.M.7
  • 38
    • 0033624445 scopus 로고    scopus 로고
    • Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis
    • Curran S, Murray GI. Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis. Eur J Cancer. 2000; 36:1621-1630.
    • (2000) Eur J Cancer , vol.36 , pp. 1621-1630
    • Curran, S.1    Murray, G.I.2
  • 39
    • 0034472617 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor invasion and metastasis
    • Stamenkovic I. Matrix metalloproteinases in tumor invasion and metastasis. Semin Cancer Biol. 2000; 10:415-433.
    • (2000) Semin Cancer Biol , vol.10 , pp. 415-433
    • Stamenkovic, I.1
  • 40
    • 34548185155 scopus 로고    scopus 로고
    • Upregulation of tissue inhibitor of matrix metalloproteinases-1 confers the anti-invasive action of cisplatin on human cancer cells
    • Ramer R, Eichele K, Hinz B. Upregulation of tissue inhibitor of matrix metalloproteinases-1 confers the anti-invasive action of cisplatin on human cancer cells. Oncogene. 2007; 26:5822-5827.
    • (2007) Oncogene , vol.26 , pp. 5822-5827
    • Ramer, R.1    Eichele, K.2    Hinz, B.3
  • 41
    • 27744503071 scopus 로고    scopus 로고
    • Latanoprost induces matrix metalloproteinase-1 expression in human nonpigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism
    • Hinz B, Rösch S, Ramer R, Tamm ER, Brune K. Latanoprost induces matrix metalloproteinase-1 expression in human nonpigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism. FASEB J. 2005; 19:1929-1931.
    • (2005) FASEB J , vol.19 , pp. 1929-1931
    • Hinz, B.1    Rösch, S.2    Ramer, R.3    Tamm, E.R.4    Brune, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.