Beneficial effects of anti-interleukin-6 antibodies on impaired gastrointestinal motility, inflammation and increased colonic permeability in a murine model of sepsis are most pronounced when administered in a preventive setup

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Nullens, Sara ^a   Staessens, Michael ^a   Peleman, Cédric ^a   Plaeke, Philip ^a   Malhotra Kumar, Surbhi ^a   Francque, Sven ^a,b   De Man, Joris G ^a   De Winter, Benedicte Y ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; AUTACOID; CELL ADHESION MOLECULE; CYTOKINE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL TRANSLOCATION; CONTROLLED STUDY; DIGESTIVE SYSTEM INFLAMMATION; DRUG EFFICACY; GASTROINTESTINAL MOTILITY DISORDER; IN VIVO STUDY; INTESTINE MUCOSA PERMEABILITY; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; SEPSIS; SURVIVAL; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CELL MEMBRANE PERMEABILITY; DISEASE MODEL; DRUG EFFECTS; GASTROINTESTINAL MOTILITY; GENETICS; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MORTALITY; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; CELL ADHESION MOLECULES; CELL MEMBRANE PERMEABILITY; CYTOKINES; DISEASE MODELS, ANIMAL; GASTROINTESTINAL MOTILITY; IMMUNOGLOBULIN G; INFLAMMATION MEDIATORS; INTERLEUKIN-6; INTESTINAL MUCOSA; MICE; MICE, KNOCKOUT; SEPSIS;

EID: 84962828786     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0152914     Document Type: Article

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