메뉴 건너뛰기




Volumn 7, Issue , 2016, Pages

CD8 + T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing

Author keywords

[No Author keywords available]

Indexed keywords

BASILIXIMAB; NATALIZUMAB; RITUXIMAB; T LYMPHOCYTE RECEPTOR; HYBRID PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY;

EID: 84962748059     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11153     Document Type: Article
Times cited : (81)

References (49)
  • 1
    • 0035986913 scopus 로고    scopus 로고
    • Advances in pathogenic concepts and therapeutic agents in Rasmussens encephalitis
    • Bien, C. G., Elger, C. E. & Wiendl, H. Advances in pathogenic concepts and therapeutic agents in Rasmussens encephalitis. Expert Opin. Investig. Drugs 11, 981-989 (2002).
    • (2002) Expert Opin. Investig. Drugs , vol.11 , pp. 981-989
    • Bien, C.G.1    Elger, C.E.2    Wiendl, H.3
  • 2
    • 84902014898 scopus 로고
    • Focal seizures due to chronic localized encephalitis
    • Rasmussen, T., Olszewski, J. & Lloyd-Smith, D. Focal seizures due to chronic localized encephalitis. Neurology 8, 435-445 (1958).
    • (1958) Neurology , vol.8 , pp. 435-445
    • Rasmussen, T.1    Olszewski, J.2    Lloyd-Smith, D.3
  • 3
    • 0036198111 scopus 로고    scopus 로고
    • Destruction of neurons by cytotoxic T cells: A new pathogenic mechanism in Rasmussens encephalitis
    • Bien, C. G. et al. Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussens encephalitis. Ann. Neurol. 51, 311-318 (2002).
    • (2002) Ann. Neurol , vol.51 , pp. 311-318
    • Bien, C.G.1
  • 4
    • 84892489621 scopus 로고    scopus 로고
    • Rasmussens encephalitis: Clinical features, pathobiology, and treatment advances
    • Varadkar, S. et al. Rasmussens encephalitis: clinical features, pathobiology, and treatment advances. Lancet Neurol. 13, 195-205 (2014).
    • (2014) Lancet Neurol , vol.13 , pp. 195-205
    • Varadkar, S.1
  • 5
    • 33750600144 scopus 로고    scopus 로고
    • Early onset Rasmussens syndrome: A malignant, often bilateral form of the disorder
    • Andermann, F. & Farrell, K. Early onset Rasmussens syndrome: a malignant, often bilateral form of the disorder. Epilepsy Res. 70(Suppl 1): S259-S262 (2006).
    • (2006) Epilepsy Res , vol.70 , pp. S259-S262
    • Andermann, F.1    Farrell, K.2
  • 7
    • 84874701167 scopus 로고    scopus 로고
    • Rasmussen encephalitis: Incidence and course under randomized therapy with tacrolimus or intravenous immunoglobulins
    • Bien, C. G. et al. Rasmussen encephalitis: incidence and course under randomized therapy with tacrolimus or intravenous immunoglobulins. Epilepsia 54, 543-550 (2013).
    • (2013) Epilepsia , vol.54 , pp. 543-550
    • Bien, C.G.1
  • 8
    • 33845531683 scopus 로고    scopus 로고
    • Adult-onset Rasmussens encephalitis: Anatomicalelectrographic- clinical features of 7 Italian cases
    • Villani, F. et al. Adult-onset Rasmussens encephalitis: anatomicalelectrographic- clinical features of 7 Italian cases. Epilepsia 47(Suppl 5): 41-46 (2006).
    • (2006) Epilepsia , vol.47 , pp. 41-46
    • Villani, F.1
  • 9
    • 0028963738 scopus 로고
    • Chronic encephalitis associated with epilepsy: Immunohistochemical and ultrastructural studies
    • Farrell, M. A. et al. Chronic encephalitis associated with epilepsy: immunohistochemical and ultrastructural studies. Acta Neuropathol. 89, 313-321 (1995).
    • (1995) Acta Neuropathol , vol.89 , pp. 313-321
    • Farrell, M.A.1
  • 10
    • 20144363551 scopus 로고    scopus 로고
    • Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: A European consensus statement
    • Bien, C. G. et al. Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: a European consensus statement. Brain 128, 454-471 (2005).
    • (2005) Brain , vol.128 , pp. 454-471
    • Bien, C.G.1
  • 11
    • 0028095257 scopus 로고
    • Autoantibodies to glutamate receptor GluR3 in Rasmussens encephalitis
    • Rogers, S. W. et al. Autoantibodies to glutamate receptor GluR3 in Rasmussens encephalitis. Science 265, 648-651 (1994).
    • (1994) Science , vol.265 , pp. 648-651
    • Rogers, S.W.1
  • 12
    • 0035940571 scopus 로고    scopus 로고
    • GluR3 antibodies: Prevalence in focal epilepsy but no specificity for Rasmussens encephalitis
    • Wiendl, H. et al. GluR3 antibodies: prevalence in focal epilepsy but no specificity for Rasmussens encephalitis. Neurology 57, 1511-1514 (2001).
    • (2001) Neurology , vol.57 , pp. 1511-1514
    • Wiendl, H.1
  • 13
    • 3242676920 scopus 로고    scopus 로고
    • Absence of antibodies to glutamate receptor type 3 (GluR3) in Rasmussen encephalitis
    • Watson, R. et al. Absence of antibodies to glutamate receptor type 3 (GluR3) in Rasmussen encephalitis. Neurology 63, 43-50 (2004).
    • (2004) Neurology , vol.63 , pp. 43-50
    • Watson, R.1
  • 14
    • 34547736919 scopus 로고    scopus 로고
    • Astrocytes are a specific immunological target in Rasmussens encephalitis
    • Bauer, J. et al. Astrocytes are a specific immunological target in Rasmussens encephalitis. Ann. Neurol. 62, 67-80 (2007).
    • (2007) Ann. Neurol , vol.62 , pp. 67-80
    • Bauer, J.1
  • 15
    • 66549102332 scopus 로고    scopus 로고
    • CD8q T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery
    • Schwab, N. et al. CD8q T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery. Brain 132, 1236-1246 (2009).
    • (2009) Brain , vol.132 , pp. 1236-1246
    • Schwab, N.1
  • 16
    • 0031066631 scopus 로고    scopus 로고
    • Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen
    • Li, Y. et al. Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen. J. Immunol. 158, 1428-1437 (1997).
    • (1997) J. Immunol , vol.158 , pp. 1428-1437
    • Li, Y.1
  • 17
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells
    • Robins, H. S. et al. Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. Blood 114, 4099-4107 (2009).
    • (2009) Blood , vol.114 , pp. 4099-4107
    • Robins, H.S.1
  • 18
    • 84855348556 scopus 로고    scopus 로고
    • Ultra-sensitive detection of rare T cell clones
    • Robins, H. et al. Ultra-sensitive detection of rare T cell clones. J. Immunol. Methods 375, 14-19 (2012).
    • (2012) J. Immunol. Methods , vol.375 , pp. 14-19
    • Robins, H.1
  • 19
    • 33748937755 scopus 로고    scopus 로고
    • Statistical analysis of CDR3 length distributions for the assessment of T and B cell repertoire biases
    • Miqueu, P. et al. Statistical analysis of CDR3 length distributions for the assessment of T and B cell repertoire biases. Mol. Immunol. 44, 1057-1064 (2007).
    • (2007) Mol. Immunol , vol.44 , pp. 1057-1064
    • Miqueu, P.1
  • 20
    • 84881272423 scopus 로고    scopus 로고
    • Rasmussen encephalitis treated with natalizumab
    • Bittner, S. et al. Rasmussen encephalitis treated with natalizumab. Neurology 81, 395-397 (2013).
    • (2013) Neurology , vol.81 , pp. 395-397
    • Bittner, S.1
  • 21
    • 84906568560 scopus 로고    scopus 로고
    • VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells
    • Schneider-Hohendorf, T. et al. VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. J. Exp. Med. 211, 1833-1846 (2014).
    • (2014) J. Exp. Med , vol.211 , pp. 1833-1846
    • Schneider-Hohendorf, T.1
  • 22
    • 84941001774 scopus 로고    scopus 로고
    • Treating a GAD65 antibody-associated limbic encephalitis with basiliximab: A case study
    • Widman, G. et al. Treating a GAD65 antibody-associated limbic encephalitis with basiliximab: a case study. Front. Neurol. 6, 167 (2015).
    • (2015) Front. Neurol , vol.6 , pp. 167
    • Widman, G.1
  • 23
    • 77951837763 scopus 로고    scopus 로고
    • Trafficking of immune cells in the central nervous system
    • Wilson, E. H., Weninger, W. & Hunter, C. A. Trafficking of immune cells in the central nervous system. J. Clin. Invest. 120, 1368-1379 (2010).
    • (2010) J. Clin. Invest , vol.120 , pp. 1368-1379
    • Wilson, E.H.1    Weninger, W.2    Hunter, C.A.3
  • 24
    • 84869885852 scopus 로고    scopus 로고
    • Crawl, cross: The T cell code to breach the blood-brain barriers
    • Engelhardt, B. & Ransohoff, R. M. Capture, crawl, cross: the T cell code to breach the blood-brain barriers. Trends Immunol. 33, 579-589 (2012).
    • (2012) Trends Immunol , vol.33 , pp. 579-589
    • Engelhardt, B.1    Capture, M.R.R.2
  • 25
    • 44949174084 scopus 로고    scopus 로고
    • Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis
    • Obermeier, B. et al. Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis. Nat. Med. 14, 688-693 (2008).
    • (2008) Nat. Med , vol.14 , pp. 688-693
    • Obermeier, B.1
  • 26
    • 0027251463 scopus 로고
    • The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments
    • Pannetier, C. et al. The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc. Natl Acad. Sci. USA 90, 4319-4323 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 4319-4323
    • Pannetier, C.1
  • 27
    • 0028096713 scopus 로고
    • Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus
    • Argaet, V. P. et al. Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus. J. Exp. Med. 180, 2335-2340 (1994).
    • (1994) J. Exp. Med , vol.180 , pp. 2335-2340
    • Argaet, V.P.1
  • 28
    • 3242782610 scopus 로고    scopus 로고
    • In-vivo dominant immune responses in aplastic anaemia: Molecular tracking of putatively pathogenetic T-cell clones by TCR beta-CDR3 sequencing
    • Risitano, A. M. et al. In-vivo dominant immune responses in aplastic anaemia: molecular tracking of putatively pathogenetic T-cell clones by TCR beta-CDR3 sequencing. Lancet 364, 355-364 (2004).
    • (2004) Lancet , vol.364 , pp. 355-364
    • Risitano, A.M.1
  • 29
    • 77956460339 scopus 로고    scopus 로고
    • Overlap and effective size of the human CD8β T cell receptor repertoire
    • Robins, H. S. et al. Overlap and effective size of the human CD8β T cell receptor repertoire. Sci. Transl. Med. 2, 47ra64-47ra64 (2010).
    • (2010) Sci. Transl. Med , vol.2 , pp. 47ra64-47ra64
    • Robins, H.S.1
  • 30
    • 84923917237 scopus 로고    scopus 로고
    • Timely and spatially regulated maturation of B and T cell repertoire during human fetal development
    • Rechavi, E. et al. Timely and spatially regulated maturation of B and T cell repertoire during human fetal development. Sci. Transl. Med. 7, 276ra25-276ra25 (2015).
    • (2015) Sci. Transl. Med , vol.7 , pp. 276ra25-276ra25
    • Rechavi, E.1
  • 31
    • 0031679991 scopus 로고    scopus 로고
    • The distribution of human TCR junctional region lengths shifts with age in both CD4 and CD8 T cells
    • Hall, M. A., Reid, J. L. & Lanchbury, J. S. The distribution of human TCR junctional region lengths shifts with age in both CD4 and CD8 T cells. Int. Immunol. 10, 1407-1419 (1998).
    • (1998) Int. Immunol , vol.10 , pp. 1407-1419
    • Hall, M.A.1    Reid, J.L.2    Lanchbury, J.S.3
  • 32
    • 0034255328 scopus 로고    scopus 로고
    • Flow cytometric analysis of the Vbeta repertoire in healthy controls
    • van den Beemd, R. et al. Flow cytometric analysis of the Vbeta repertoire in healthy controls. Cytometry 40, 336-345 (2000).
    • (2000) Cytometry , vol.40 , pp. 336-345
    • Van Den Beemd, R.1
  • 33
    • 0027792528 scopus 로고
    • T cells specific for viral antigens presented by HLA-Dw4 recognize DR13 on allogeneic cells: A possible mechanism for induction of rejection
    • Gjertsen, H. A., Lundin, K. E., Hansen, T. & Thorsby, E. T cells specific for viral antigens presented by HLA-Dw4 recognize DR13 on allogeneic cells: a possible mechanism for induction of rejection. Transpl. Immunol. 1, 126-131 (1993).
    • (1993) Transpl. Immunol , vol.1 , pp. 126-131
    • Gjertsen, H.A.1    Lundin, K.E.2    Hansen, T.3    Thorsby, E.4
  • 34
    • 0027406406 scopus 로고
    • Selection for T-cell receptor v beta-D beta-J beta gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis
    • Oksenberg, J. R. et al. Selection for T-cell receptor V beta-D beta-J beta gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. Nature 362, 68-70 (1993).
    • (1993) Nature , vol.362 , pp. 68-70
    • Oksenberg, J.R.1
  • 35
    • 84937542605 scopus 로고    scopus 로고
    • Evidence for the involvement of gamma delta T cells in the immune response in Rasmussen encephalitis
    • Owens, G. C. et al. Evidence for the involvement of gamma delta T cells in the immune response in Rasmussen encephalitis. J. Neuroinflammation 12, 134 (2015).
    • (2015) J. Neuroinflammation , vol.12 , pp. 134
    • Owens, G.C.1
  • 36
    • 84864048505 scopus 로고    scopus 로고
    • Highly skewed T-cell receptor V-beta chain repertoire in the bone marrow is associated with response to immunosuppressive drug therapy in children with very severe aplastic anemia
    • Schuster, F. R. et al. Highly skewed T-cell receptor V-beta chain repertoire in the bone marrow is associated with response to immunosuppressive drug therapy in children with very severe aplastic anemia. Blood Cancer J. 1, e8 (2011).
    • (2011) Blood Cancer J , vol.1 , pp. e8
    • Schuster, F.R.1
  • 38
    • 35648948324 scopus 로고    scopus 로고
    • Multiple sclerosis: T-cell receptor expression in distinct brain regions
    • Junker, A. et al. Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain 130, 2789-2799 (2007).
    • (2007) Brain , vol.130 , pp. 2789-2799
    • Junker, A.1
  • 39
    • 84896775850 scopus 로고    scopus 로고
    • T cell repertoire following autologous stem cell transplantation for multiple sclerosis
    • Muraro, P. A. et al. T cell repertoire following autologous stem cell transplantation for multiple sclerosis. J. Clin. Invest. 124, 1168-1172 (2014).
    • (2014) J. Clin. Invest , vol.124 , pp. 1168-1172
    • Muraro, P.A.1
  • 40
    • 84886790652 scopus 로고    scopus 로고
    • Rituximab-induced T cell depletion in patients with rheumatoid arthritis: Association with clinical response
    • Mélet, J. et al. Rituximab-induced T cell depletion in patients with rheumatoid arthritis: association with clinical response. Arthritis Rheum. 65, 2783-2790 (2013).
    • (2013) Arthritis Rheum , vol.65 , pp. 2783-2790
    • Mélet, J.1
  • 41
    • 33646347610 scopus 로고    scopus 로고
    • Immune surveillance in multiple sclerosis patients treated with natalizumab
    • Stüve, O. et al. Immune surveillance in multiple sclerosis patients treated with natalizumab. Ann. Neurol. 59, 743-747 (2006).
    • (2006) Ann. Neurol , vol.59 , pp. 743-747
    • Stüve, O.1
  • 42
    • 67650032747 scopus 로고    scopus 로고
    • Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells
    • Kivisäkk, P. et al. Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells. Neurology 72, 1922-1930 (2009).
    • (2009) Neurology , vol.72 , pp. 1922-1930
    • Kivisäkk, P.1
  • 43
    • 84888261112 scopus 로고    scopus 로고
    • Natalizumab affects the T-cell receptor repertoire in patients with multiple sclerosis
    • Warnke, C. et al. Natalizumab affects the T-cell receptor repertoire in patients with multiple sclerosis. Neurology 81, 1400-1408 (2013).
    • (2013) Neurology , vol.81 , pp. 1400-1408
    • Warnke, C.1
  • 44
    • 33747077896 scopus 로고    scopus 로고
    • Reconstitution of paired T cell receptor alpha- and beta-chains from microdissected single cells of human inflammatory tissues
    • Seitz, S. et al. Reconstitution of paired T cell receptor alpha- and beta-chains from microdissected single cells of human inflammatory tissues. Proc. Natl Acad. Sci. USA 103, 12057-12062 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 12057-12062
    • Seitz, S.1
  • 45
    • 84892159495 scopus 로고    scopus 로고
    • Preparing unbiased T-cell receptor and antibody cDNA libraries for the deep next generation sequencing profiling
    • Mamedov, I. Z. et al. Preparing unbiased T-cell receptor and antibody cDNA libraries for the deep next generation sequencing profiling. Front. Immunol. 4, 456 (2013).
    • (2013) Front. Immunol , vol.4 , pp. 456
    • Mamedov, I.Z.1
  • 46
    • 84900860392 scopus 로고    scopus 로고
    • Using synthetic templates to design an unbiased multiplex PCR assay
    • Carlson C. S. et al. Using synthetic templates to design an unbiased multiplex PCR assay. Nat. Commun 4 2680(2013).
    • (2013) Nat. Commun , vol.4 , Issue.2680
    • Carlson, C.S.1
  • 47
    • 0002947255 scopus 로고    scopus 로고
    • A mathematical theory of communication. ACM SIGMOBILE Mobile Comput
    • Shannon C. E. A mathematical theory of communication. ACM SIGMOBILE Mobile Comput. Commun. Rev 5 3-55(2001).
    • (2001) Commun. Rev , vol.5 , pp. 3-55
    • Shannon, C.E.1
  • 48
    • 84943610604 scopus 로고    scopus 로고
    • TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL
    • Kirsch, I. R. et al. TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL. Sci. Transl. Med. 7, 308ra158-308ra158 (2015).
    • (2015) Sci. Transl. Med , vol.7 , pp. 308ra158-308ra158
    • Kirsch, I.R.1
  • 49
    • 84885792599 scopus 로고    scopus 로고
    • High-throughput sequencing of isletinfiltrating memory CD4β T cells reveals a similar pattern of TCR Vb usage in prediabetic and diabetic NOD mice
    • Marrero, I., Hamm, D. E. & Davies, J. D. High-throughput sequencing of isletinfiltrating memory CD4β T cells reveals a similar pattern of TCR Vb usage in prediabetic and diabetic NOD mice. PLoS ONE 8, e76546 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e76546
    • Marrero, I.1    Hamm, D.E.2    Davies, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.