Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 14, 2016, Pages 3861-3866

  Hamilton, Jennifer R ^a   Sachs, David ^a   Lim, Jean K ^a   Langlois, Ryan A ^a,b   Palese, Peter ^a   Heaton, Nicholas S ^a,c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative cell fate; Antiviral immunity; Influenza virus; RNA sequencing

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNITY; IMMUNOMODULATION; INFLUENZA A; INNATE IMMUNITY; MOUSE; NEXT GENERATION SEQUENCING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; C57BL MOUSE; CELL LINE; CROSS PROTECTION; DOG; HEK293 CELL LINE; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INFLUENZA; INFLUENZA A VIRUS (H1N1); LUNG; MDCK CELL LINE; ORTHOMYXOVIRUS INFECTION; VIROLOGY;

CYTOKINE;

ANIMALS; CELL LINE; CROSS PROTECTION; CYTOKINES; DOGS; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; LUNG; MADIN DARBY CANINE KIDNEY CELLS; MICE; MICE, INBRED C57BL; ORTHOMYXOVIRIDAE INFECTIONS;

EID: 84962670317     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1522376113     Document Type: Article

References (31)

1. Walzl G, Tafuro S, Moss P, Openshaw PJ, Hussell T (2000) Influenza virus lung infection protects from respiratory syncytial virus-induced immunopathology. J Exp Med 192(9):1317-1326.
2. Laurie KL, et al. (2010) Multiple infections with seasonal influenza A virus induce cross-protective immunity against A(H1N1) pandemic influenza virus in a ferret model. J Infect Dis 202(7):1011-1020.
3. Laurie KL, et al. (2015) Interval Between Infections and Viral Hierarchy Are Determinants of Viral Interference Following Influenza Virus Infection in a Ferret Model. J Infect Dis 212(11):1701-1710.
4. Cowling BJ, et al. (2012) Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine. Clin Infect Dis 54(12): 1778-1783.
5. Piedra PA, et al. (2005) Live attenuated influenza vaccine, trivalent, is safe in healthy children 18 months to 4 years, 5 to 9 years, and 10 to 18 years of age in a communitybased, nonrandomized, open-label trial. Pediatrics 116(3):e397-e407.
6. Kelly H, Barry S, Laurie K, Mercer G (2010) Seasonal influenza vaccination and the risk of infection with pandemic influenza: A possible illustration of non-specific temporary immunity following infection. Euro Surveill 15(47):19722.
7. Cowling BJ, Nishiura H (2012) Virus interference and estimates of influenza vaccine effectiveness from test-negative studies. Epidemiology 23(6):930-931.
8. Ferguson NM, Galvani AP, Bush RM (2003) Ecological and immunological determinants of influenza evolution. Nature 422(6930):428-433.
9. Hirsh S, et al. (2014) Epidemiological changes of respiratory syncytial virus (RSV) infections in Israel. PLoS One 9(3):e90515.
10. Casalegno JS, et al. (2010) Impact of the 2009 influenza A(H1N1) pandemic wave on the pattern of hibernal respiratory virus epidemics, France, 2009. Euro Surveill 15(6):19485.
11. Mak GC, Wong AH, Ho WY, Lim W(2012) The impact of pandemic influenza A (H1N1) 2009 on the circulation of respiratory viruses 2009-2011. Influenza Other Respi Viruses 6(3):e6-e10.
12. Heaton NS, et al. (2014) Long-term survival of influenza virus infected club cells drives immunopathology. J Exp Med 211(9):1707-1714.
13. Madisen L, et al. (2010) A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci 13(1):133-140.
14. Krammer F, Pica N, Hai R, Margine I, Palese P (2013) Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies. J Virol 87(12):6542-6550.
15. Bracci L, et al. (2005) Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level. Vaccine 23(23):2994-3004.
16. Yahaya B (2012) Understanding cellular mechanisms underlying airway epithelial repair: Selecting the most appropriate animal models. Scientific World Journal 2012: 961684.
17. Crosby LM, Waters CM (2010) Epithelial repair mechanisms in the lung. Am J Physiol Lung Cell Mol Physiol 298(6):L715-L731.
18. La Gruta NL, Kedzierska K, Stambas J, Doherty PC (2007) A question of self-preservation: Immunopathology in influenza virus infection. Immunol Cell Biol 85(2):85-92.
19. Buch T, et al. (2005) A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat Methods 2(6):419-426.
20. Monticelli LA, et al. (2011) Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol 12(11):1045-1054.
21. Holtzman MJ, Byers DE, Alexander-Brett J, Wang X (2014) The role of airway epithelial cells and innate immune cells in chronic respiratory disease. Nat Rev Immunol 14(10):686-698.
22. Hogan BL, et al. (2014) Repair and regeneration of the respiratory system: Complexity, plasticity, and mechanisms of lung stem cell function. Cell Stem Cell 15(2): 123-138.
23. Moyron-Quiroz JE, et al. (2004) Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity. Nat Med 10(9):927-934.
24. +T cells during infection with influenza virus due to selective expression of IFITM3. Nat Immunol 14(3):238-245.
25. Sheridan BS, Lefrançois L (2011) Regional and mucosal memory T cells. Nat Immunol 12(6):485-491.
26. Quintin J, Cheng SC, van der Meer JW, Netea MG (2014) Innate immune memory: Towards a better understanding of host defense mechanisms. Curr Opin Immunol 29: 1-7.
27. Schenkel JM, et al. (2014) T cell memory. Resident memory CD8 T cells trigger protective innate and adaptive immune responses. Science 346(6205):98-101.
28. Schenkel JM, Masopust D (2014) Tissue-resident memory T cells. Immunity 41(6): 886-897.
29. Pavlidis P, Noble WS (2003) Matrix2png: A utility for visualizing matrix data. Bioinformatics 19(2):295-296.
30. Hermann M, et al. (2014) Binary recombinase systems for high-resolution conditional mutagenesis. Nucleic Acids Res 42(6):3894-3907.
31. Sourisseau M, et al. (2013) Temporal analysis of hepatitis C virus cell entry with occludin directed blocking antibodies. PLoS Pathog 9(3):e1003244.