Isoquercetin ameliorates tunicamycin-induced apoptosis in rat dorsal root ganglion neurons via suppressing ROS-dependent endoplasmic reticulum stress

Biomedicine and Pharmacotherapy

Volumn 80, Issue , 2016, Pages 343-351

  Lu, Tan ^a   Zhang, Chao ^a   Chai, Mingxiang ^a   An, Yongbo ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; DRG neurons; ER stress; Isoquercetin; Mitochondrial dysfunction

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 12; CASPASE 3; CASPASE 9; CYTOCHROME C; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; ISOQUERCETIN; LACTATE DEHYDROGENASE; MESSENGER RNA; NEUROPROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN IRE1; PROTEIN IRE1ALPHA; PUMA PROTEIN; QUERCETIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; TUNICAMYCIN; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; CASPASE; QUERCETIN; THIADIAZOLE DERIVATIVE; YLT256;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL STIMULATION; COLORIMETRY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; IMMUNOFLUORESCENCE; MTT ASSAY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPINAL GANGLION; STAINING; TUNEL ASSAY; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; ANIMAL; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; SPRAGUE DAWLEY RAT; SYNTHESIS;

ANIMALS; APOPTOSIS; BENZAMIDES; CASPASES; CELL SURVIVAL; CYTOCHROMES C; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; L-LACTATE DEHYDROGENASE; MITOCHONDRIA; NEURONS; QUERCETIN; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; THIADIAZOLES; TUNICAMYCIN; UNFOLDED PROTEIN RESPONSE;

EID: 84962647800     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.03.039     Document Type: Article

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