Alterations of microRNA-124 expression in peripheral blood mononuclear cells in pre- and post-treatment patients with major depressive disorder

Journal of Psychiatric Research

Volumn 78, Issue , 2016, Pages 65-71

  He, Shen ^a   Liu, Xiaohua ^a   Jiang, Kaida ^a   Peng, Daihui ^a   Hong, Wu ^a   Fang, Yiru ^a   Qian, Yiping ^a   Yu, Shunying ^a   Li, Huafang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Expression; Major depressive disorder; MicroRNA; MiR 124; PBMC; Treatment

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; DULOXETINE; ESCITALOPRAM; FLUOXETINE; MICRORNA 124; MIRTAZAPINE; PAROXETINE; SERTRALINE; VENLAFAXINE; BIOLOGICAL MARKER; MICRORNA; MIRN124 MICRORNA, HUMAN;

ADULT; ANTIDEPRESSANT ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE TARGETING; HUMAN; MAJOR DEPRESSION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEIVER OPERATING CHARACTERISTIC; RNA EXTRACTION; SENSITIVITY AND SPECIFICITY; BLOOD; DEPRESSIVE DISORDER, MAJOR; DRUG EFFECTS; FOLLOW UP; METABOLISM; MONONUCLEAR CELL; TREATMENT OUTCOME;

ADULT; ANTIDEPRESSIVE AGENTS; AREA UNDER CURVE; BIOMARKERS; DEPRESSIVE DISORDER, MAJOR; FEMALE; FOLLOW-UP STUDIES; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; ROC CURVE; TREATMENT OUTCOME;

EID: 84962629559     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2016.03.015     Document Type: Article

References (49)

1. American Psychiatric Association Practice guideline for the treatment of major depressive disorder. Am. J. Psychiatry 2010, 167:10. third ed.
2. Atarod S., Smith H., Dickinson A., Wang X.N. MicroRNA levels quantified in whole blood varies from PBMCs. F1000Res 2014, 3:183.
3. Belzeaux R., Bergon A., Jeanjean V., Loriod B., Formisano-Tréziny C., Verrier L., et al. Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode. Transl. Psychiatry 2012, 2(11):e185.
4. Bahi A., Chandrasekar V., Dreyer J.L. Selective lentiviral-mediated suppression of microRNA124a in the hippocampus evokes antidepressants-like effects in rats. Psychoneuroendocrinology 2014, 46:78-87.
5. Beasley C., Cotter D., Everall I. An investigation of the Wnt-signalling pathway in the prefrontal cortex in schizophrenia, bipolar disorder and major depressive disorder. Schizophr. Res. 2002, 58:63-67.
6. Bateman J.M., McNeill H. Insulin/IGF signalling in neurogenesis. Cell Mol. Life Sci. 2006, 63(15):1701-1705.
7. Bocchio-Chiavetto L., Maffioletti E., Bettinsoli P., Giovannini C., Bignotti S., Tardito D., et al. Blood microRNA changes in depressed patients during antidepressant treatment. Eur. Neuropsychopharmacol. 2013, 23(7):602-611.
8. Cooke S.F., Bliss T.V. Plasticity in the human central nervous system. Brain 2006, 129(Pt 7):1659-1673.
9. Cao M.Q., Chen D.H., Zhang C.H., Wu Z.Z. Screening of specific microRNA in hippocampus of depression model rats and intervention effect of Chaihu Shugan San. Zhong guo Zhong Yao ZaZhi 2013, 38(10):1585-1589.
10. Chandrasekar V., Dreyer J.L. microRNAs miR-124, let-7d and miR-181a regulate cocaine-induced plasticity. Mol. Cell Neurosci. 2009, 42(4):350-362.
11. Cheng L.C., Pastrana E., Tavazoie M., Doetsch F. miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat. Neurosci. 2009, 12(4):399-408.
12. Duman R.S. Pathophysiology of depression: the concept of synaptic plasticity. Eur. Psychiatry 2002, 3(17 Suppl. l):306-310.
13. Duman R.S., Li N. A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists. Philos. Trans. R. Soc. Lond B Biol.Sci. 2012, 367(1601):2475-2484.
14. da Huang W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4(1):44-57.
15. Flynt A.S., Lai E.C. Biological principles of microRNA-mediated regulation: shared themes amid diversity. Nat. Rev. Genet. 2008, 9(11):831-842.
16. Fisar Z., Raboch J. Depression, antidepressants, and peripheral blood components. Neuro Endocrinol. Lett. 2008, 29(1):17-28.
17. Fan H.M., Sun X.Y, Guo W., Zhong A.F., Niu W., Zhao L., et al. Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients. J. Psychiatr. Res. 2014, 59:45-52.
18. Fan H.M., Sun X.Y., Niu W., Zhao L., Zhang Q.L., Li W.S. Altered microRNA expression in peripheral blood mononuclear cells from young patients with schizophrenia. J. Mol. Neurosci. 2015, 56(3):562-571.
19. Gladkevich A., Kauffman H.F., Korf J. Lymphocytes as a neural probe: potential for studying psychiatric disorders. Prog. Neuropsychopharmacol. Biol. Psychiatry 2004, 28(3):559-576.
20. Gormanns P., Mueller N.S., Ditzen C., Wolf S., Holsboer F., Turck C.W. Phenome-transcriptome correlation unravels anxiety and depression related pathways. J. Psychiatr. Res. 2011, 45(7):973-979.
21. Iwamoto K., Kato T. RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders. Neurosci. Lett. 2003, 346(3):169-172.
22. Kosik K.S. The neuronal microRNA system. Nat. Rev. Neurosci. 2006, 7:911-920.
23. Klok M.D., Alt S.R., Irurzun Lafitte A.J., Turner J.D., Lakke E.A., Huitinga I., et al. Decreased expression of mineralocorticoid receptor mRNA and its splice variants in postmortem brain regions of patients with major depressive disorder. J. Psychiatr. Res. 2011, 45(7):871-878.
24. Kao C.F., Jia P., Zhao Z., Kuo P.H. Enriched pathways for major depressive disorder identified from a genome-wide association study. Int. J. Neuropsychopharmacol. 2012, 15(10):1401-1411.
25. Kohli M.A., Lucae S., Saemann P.G., Schmidt M.V., Demirkan A., Hek K., et al. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron 2011, 70(2):252-265.
26. Kripke D.F., Nievergelt C.M., Tranah G.J., Murray S.S., Rex K.M., Grizas A.P., et al. FMR1, circadian genes and depression: suggestive associations or false discovery?. J. Circadian Rhythms 2013, 11(1):3.
27. Kishi T., Yoshimura R., Fukuo Y., Kitajima T., Okochi T., Matsunaga S., et al. The CLOCK gene and mood disorders: a case-control study and meta-analysis. Chronobiol Int. 2011, 28(9):825-833.
28. Lopez J.P., Lim R., Cruceanu C., Crapper L., Fasano C., Labonte B., et al. miR-1202: a primate specific and brain enriched miRNA involved in major depression and antidepressant treatment. Nat. Med. 2014, 20(7):764-768.
29. Liang Y., Ridzon D., Wong L., Chen C. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 2007, 8:166.
30. Lagos-Quintana M., Rauhut R., Yalcin A., Meyer J., Lendeckel W., Tuschl T. Identification of tissue-specific microRNAs from mouse. Curr. Biol. 2002, 12(9):735-739.
31. Li Y.J., Xu M., Gao Z.H., Wang Y.Q., Yue Z., Zhang Y.X., et al. Alterations of serum levels of BDNF-related miRNAs in patients with depression. PLoS One 2013, 8(5):e63648.
32. Lai C.Y., Yu S.L., Hsieh M.H., Chen C.H., Chen H.Y., Wen C.C., et al. MicroRNA expression aberration as potential peripheral blood biomarkers for schizophrenia. PLoS One 2011, 6(6):e21635.
33. Makeyev E.V., Zhang J., Carrasco M.A., Maniatis T. The MicroRNA miR-124 Promotes Neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell. 2007, 27(3):435-448.
34. Pan Y., Hong Y., Zhang Q.Y., Kong L.D. Impaired hypothalamic insulin signaling in CUMS rats: restored by icariin and fluoxetine through inhibiting CRF system. Psychoneuroendocrinology 2013, 38(1):122-134.
35. Piñero J., Queralt-Rosinach N., Bravo À Deu-Pons J., Bauer-Mehren A., Baron M., et al. DisGeNET: a Discovery Platform for the Dynamical Exploration of Human Diseases and Their Genes 2015, Database, Oxford, bav028.
36. Ryan K.M., O'Donovan S.M., McLoughlin D.M. Electroconvulsive stimulation alters levels of BDNF-associated microRNAs. Neurosci. Lett. 2013, 549:125-129.
37. Ray M.T., Shannon Weickert C., Webster M.J. Decreased BDNF and TrkB mRNA expression in multiple cortical areas of patients with schizophrenia and mood disorders. Transl. Psychiatry 2014, 4(5):e389.
38. Sullivan P.F., Fan C., Perou C.M. Evaluating the comparability of gene expression in blood and brain. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2006, 141(B):261-268.
39. Su M., Hong J., Zhao Y., Liu S., Xue X. MeCP2 controls hippocampal brain-derived neurotrophic factor expression via homeostatic interactions with microRNA-132 in rats with depression. Mol. Med. Rep. 2015, 12(4):5399-5406.
40. Song G.G., Kim J.H., Lee Y.H. Genome-wide pathway analysis in major depressive disorder. J. Mol. Neurosci. 2013, 51(2):428-436.
41. Schmittgen T.D., Livak K.J. Analyzing real-time PCR data by the comparative CT method. Nat. Protoc. 2008, 3(6):1101-1108.
42. Smalheiser N.R., Lugli G., Rizavi H.S., Torvik V.I., Turecki G., Dwivedi Y. MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects. PLoS One 2012, 7(3):e33201.
43. Smalheiser N.R., Lugli G., Zhang H., Rizavi H., Cook E.H., Dwivedi Y. Expression of microRNAs and other small RNAs in prefrontal cortex in schizophrenia, bipolar disorder and depressedsubjects. PLoS One 2014, 9(1):e86469.
44. Van Battum E.Y., Brignani S., Pasterkamp R.J. Axon guidance proteins in neurological disorders. Lancet Neurol. 2015, 14(5):532-546.
45. Wan Y., Liu Y., Wang X., Wu J., Liu K., Zhou J., et al. Identification of differential microRNAs in cerebrospinal fluid and serum of patients with major depressive disorder. PLoS One 2015, 10(3):e0121975.
46. Wang X., Sundquist K., Hedelius A., Palmér K., Memon A.A., Sundquist J. Circulating microRNA-144-5p is associated with depressive disorders. Clin. Epigenetics 2015, 7(1):69.
47. Xiao F., Zuo Z., Cai G., Kang S., Gao X., Li T. miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res. 2009, 37:D105-D110.
48. Zeng Y. Regulation of the mammalian nervous system by microRNAs. MolPharmacol 2009, 75(2):259-264.
49. Zubenko GS, Hughes HB, Jordan RM, Lyons-Weiler J, Cohen BM Differential hippocampal gene expression and pathway analysis in an etiology-based mousemodel of major depressive disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2014, 165B(6):457-466.