Relationship between hepatic progenitor cell-mediated liver regeneration and non-parenchymal cells

Hepatology Research

Volumn 46, Issue 12, 2016, Pages 1187-1193

  Kitade, Mitsuteru ^a   Kaji, Kosuke ^a   Yoshiji, Hitoshi ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

hepatic progenitor cells; hepatic stellate cells; macrophages

Indexed keywords

BETA CATENIN; CHEMOKINE; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 2; KERATINOCYTE GROWTH FACTOR; NOTCH RECEPTOR; PROTEIN TWEAK; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; WNT3A PROTEIN;

CELL LINEAGE; CYTOKINE RELEASE; HEPATIC PROGENITOR CELL; HUMAN; LIVER REGENERATION; NONHUMAN; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVIEW; SIGNAL TRANSDUCTION; STELLATE CELL; STEM CELL NICHE;

EID: 84962627890     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/hepr.12682     Document Type: Review

References (51)

1. Michalopoulos GK. Liver regeneration. J Cell Physiol 2007; 213: 286–300.
2. Rehman K, Iqbal MJ, Zahra N, Akash MS. Liver stem cells: from preface to advancements. Curr Stem Cell Res Ther 2014; 9: 10–21.
3. Miyajima A, Tanaka M, Itoh T. Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming. Cell Stem Cell 2014; 14: 561–74.
4. Best J, Dolle L, Manka P, Coombes J, van Grunsven LA, Syn WK. Role of liver progenitors in acute liver injury. Front Physiol 2013; 4: 258.
5. Shin S, Kaestner KH. The origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells. Curr Top Dev Biol 2014; 107: 269–92.
6. Tanimizu N, Mitaka T. Re-evaluation of liver stem/progenitor cells. Organogenesis 2014; 10: 208–15.
7. Duncan AW, Dorrell C, Grompe M. Stem cells and liver regeneration. Gastroenterology 2009; 137: 466–81.
8. Hindley CJ, Mastrogiovanni G, Huch M. The plastic liver: differentiated cells, stem cells, every cell? J Clin Invest 2014; 124: 5099–102.
9. Wang B, Zhao L, Fish M, Logan CY, Nusse R. Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver. Nature 2015; 524: 180–5.
10. Furuyama K, Kawaguchi Y, Akiyama H et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet 2011; 43: 34–41.
11. Espanol-Suner R, Carpentier R, Van Hul N et al. Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice. Gastroenterology 2012; 143: 1564–75 e7.
12. Carpentier R, Suner RE, van Hul N et al. Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology 2011; 141: 1432–8.
13. Rodrigo-Torres D, Affo S, Coll M et al. The biliary epithelium gives rise to liver progenitor cells. Hepatology 2014; 60: 1367–77.
14. Tarlow BD, Finegold MJ, Grompe M. Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury. Hepatology 2014; 60: 278–89.
15. Shin S, Upadhyay N, Greenbaum LE, Kaestner KH. Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury. Gastroenterology 2015; 148: 192–202 e3.
16. Malato Y, Naqvi S, Schurmann N et al. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. J Clin Invest 2011; 121: 4850–60.
17. Yanger K, Zong Y, Maggs LR et al. Robust cellular reprogramming occurs spontaneously during liver regeneration. Genes Dev 2013; 27: 719–24.
18. Font-Burgada J, Shalapour S, Ramaswamy S et al. Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer. Cell 2015; 162: 766–79.
19. Choi TY, Ninov N, Stainier DY, Shin D. Extensive conversion of hepatic biliary epithelial cells to hepatocytes after near total loss of hepatocytes in zebrafish. Gastroenterology 2014; 146: 776–88.
20. Chen YH, Chang MH, Chien CS, Wu SH, Yu CH, Chen HL. Contribution of mature hepatocytes to small hepatocyte-like progenitor cells in retrorsine-exposed rats with chimeric livers. Hepatology 2013; 57: 1215–24.
21. Tirnitz-Parker JE, Viebahn CS, Jakubowski A et al. Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells. Hepatology 2010; 52: 291–302.
22. Liu D, Yovchev MI, Zhang J et al. Identification and characterization of mesenchymal-epithelial progenitor-like cells in normal and injured rat liver. Am J Pathol 2015; 185: 110–28.
23. Dwyer BJ, Olynyk JK, Ramm GA, Tirnitz-Parker JE. TWEAK and LTbeta signaling during chronic liver disease. Front Immunol 2014; 5: 39.
24. Karaca G, Swiderska-Syn M, Xie G et al. TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice. PLoS One 2014; 9: e83987.
25. Kuramitsu K, Sverdlov DY, Liu SB et al. Failure of fibrotic liver regeneration in mice is linked to a severe fibrogenic response driven by hepatic progenitor cell activation. Am J Pathol 2013; 183: 182–94.
26. Jakubowski A, Ambrose C, Parr M et al. TWEAK induces liver progenitor cell proliferation. J Clin Invest 2005; 115: 2330–40.
27. Bird TG, Lu WY, Boulter L et al. Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling. Proc Natl Acad Sci U S A 2013; 110: 6542–7.
28. Sawitza I, Kordes C, Reister S, Haussinger D. The niche of stellate cells within rat liver. Hepatology 2009; 50: 1617–24.
29. Hsieh WC, Mackinnon AC, Lu WY et al. Galectin-3 regulates hepatic progenitor cell expansion during liver injury. Gut 2015; 64: 312–21.
30. Vestentoft PS, Jelnes P, Andersen JB et al. Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair. Fibrogenesis Tissue Repair 2013; 6: 21.
31. Williams MJ, Clouston AD, Forbes SJ. Links between hepatic fibrosis, ductular reaction, and progenitor cell expansion. Gastroenterology 2014; 146: 349–56.
32. Takase HM, Itoh T, Ino S et al. FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev 2013; 27: 169–81.
33. Ishikawa T, Factor VM, Marquardt JU et al. Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice. Hepatology 2012; 55: 1215–26.
34. Nakamura T, Teramoto H, Ichihara A. Purification and characterization of a growth factor from rat platelets for mature parenchymal hepatocytes in primary cultures. Proc Natl Acad Sci U S A 1986; 83: 6489–93.
35. Kitade M, Factor VM, Andersen JB et al. Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling. Genes Dev 2013; 27: 1706–17.
36. Dezso K, Jelnes P, Laszlo V et al. Thy-1 is expressed in hepatic myofibroblasts and not oval cells in stem cell-mediated liver regeneration. Am J Pathol 2007; 171: 1529–37.
37. Si-Tayeb K, Noto FK, Nagaoka M et al. Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology 2010; 51: 297–305.
38. Kamiya A, Kinoshita T, Ito Y et al. Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer. EMBO J 1999; 18: 2127–36.
39. Boulter L, Govaere O, Bird TG et al. Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med 2012; 18: 572–9.
40. Si-Tayeb K, Lemaigre FP, Duncan SA. Organogenesis and development of the liver. Dev Cell 2010; 18: 175–89.
41. Antoniou A, Raynaud P, Cordi S et al. Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology 2009; 136: 2325–33.
42. Geisler F, Nagl F, Mazur PK et al. Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. Hepatology 2008; 48: 607–16.
43. Hunter MP, Wilson CM, Jiang X et al. The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis. Dev Biol 2007; 308: 355–67.
44. Yanai M, Tatsumi N, Hasunuma N, Katsu K, Endo F, Yokouchi Y. FGF signaling segregates biliary cell-lineage from chick hepatoblasts cooperatively with BMP4 and ECM components in vitro. Dev Dyn 2008; 237: 1268–83.
45. Oda T, Elkahloun AG, Pike BL et al. Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nat Genet 1997; 16: 235–42.
46. Zong Y, Panikkar A, Xu J et al. Notch signaling controls liver development by regulating biliary differentiation. Development 2009; 136: 1727–39.
47. Tanimizu N, Miyajima A, Mostov KE. Liver progenitor cells develop cholangiocyte-type epithelial polarity in three-dimensional culture. Mol Biol Cell 2007; 18: 1472–9.
48. Tanimizu N, Miyajima A. Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors. J Cell Sci 2004; 117: 3165–74.
49. Suzuki K, Tanaka M, Watanabe N, Saito S, Nonaka H, Miyajima A. p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver. Gastroenterology 2008; 135: 270–81 e3.
50. Sparks EE, Huppert KA, Brown MA, Washington MK, Huppert SS. Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice. Hepatology 2010; 51: 1391–400.
51. Tchorz JS, Kinter J, Muller M, Tornillo L, Heim MH, Bettler B. Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice. Hepatology 2009; 50: 871–9.