-
1
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in atg7-Deficient mice
-
Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, Kominami E, Tanaka K, Chiba T: Impairment of starvation-induced and constitutive autophagy in Atg7-Deficient mice. J Cell Biol 2005;169:425-434.
-
(2005)
J Cell Biol
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
Kominami, E.11
Tanaka, K.12
Chiba, T.13
-
2
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, Ohsumi Y, Tokuhisa T, Mizushima N: The role of autophagy during the early neonatal starvation period. Nature 2004;432:1032-1036.
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
Yamamoto, A.4
Nakaya, H.5
Yoshimori, T.6
Ohsumi, Y.7
Tokuhisa, T.8
Mizushima, N.9
-
3
-
-
67649607465
-
Autophagy, immunity, and microbial adaptations
-
Deretic V, Levine B: Autophagy, immunity, and microbial adaptations. Cell Host Microbe 2009;5:527-549.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 527-549
-
-
Deretic, V.1
Levine, B.2
-
4
-
-
70349924078
-
Links between autophagy, innate immunity, inflammation and Crohn's disease
-
Deretic V: Links between autophagy, innate immunity, inflammation and Crohn's disease. Dig Dis 2009;27:246-251.
-
(2009)
Dig Dis
, vol.27
, pp. 246-251
-
-
Deretic, V.1
-
5
-
-
0142027948
-
Ways of dying: Multiple pathways to apoptosis
-
Adams JM: Ways of dying: multiple pathways to apoptosis. Genes Dev 2003;17:2481-2495.
-
(2003)
Genes Dev
, vol.17
, pp. 2481-2495
-
-
Adams, J.M.1
-
6
-
-
0034329418
-
LC3, a mammalian homologue of yeast apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T: LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000;19:5720-5728.
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
7
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N: Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 2003;100:15077-15082.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
8
-
-
32244442749
-
Functional specificity of the mammalian beclin-vps34 pi 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
-
Zeng X, Overmeyer JH, Maltese WA: Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking. J Cell Sci 2006;119:259-270.
-
(2006)
J Cell Sci
, vol.119
, pp. 259-270
-
-
Zeng, X.1
Overmeyer, J.H.2
Maltese, W.A.3
-
9
-
-
34249037565
-
Crystal structure of the bcl-xl-beclin 1 peptide complex: Beclin 1 is a novel bh3-only protein
-
Oberstein A, Jeffrey PD, Shi Y: Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J Biol Chem 2007;282:13123-13132.
-
(2007)
J Biol Chem
, vol.282
, pp. 13123-13132
-
-
Oberstein, A.1
Jeffrey, P.D.2
Shi, Y.3
-
10
-
-
0001488499
-
Protection against fatal sindbis virus encephalitis by beclin, a novel bcl-2-interacting protein
-
Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, Herman B, Levine B: Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol 1998;72:8586-8596.
-
(1998)
J Virol
, vol.72
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
Gordon, G.4
Goldman, J.E.5
Berry, G.6
Herman, B.7
Levine, B.8
-
11
-
-
33745953139
-
BCL-2 in the crosshairs: Tipping the balance of life and death
-
Walensky LD: BCL-2 in the crosshairs: tipping the balance of life and death. Cell Death Differ 2006;13:1339-1350.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1339-1350
-
-
Walensky, L.D.1
-
12
-
-
37549048249
-
The bcl-2 protein family: Opposing activities that mediate cell death
-
Youle RJ, Strasser A: The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008;9:47-59.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
13
-
-
44949237240
-
JNK1-mediated phosphorylation of bcl-2 regulates starvation-induced autophagy
-
Wei Y, Pattingre S, Sinha S, Bassik M, Levine B: JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008;30:678-688.
-
(2008)
Mol Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
14
-
-
0034614658
-
Translocation of sapk/jnk to mitochondria and interaction with bcl-x(l) in response to DNA damage
-
Kharbanda S, Saxena S, Yoshida K, Pandey P, Kaneki M, Wang Q, Cheng K, Chen YN, Campbell A, Sudha T, Yuan ZM, Narula J, Weichselbaum R, Nalin C, Kufe D: Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage. J Biol Chem 2000;275:322-327.
-
(2000)
J Biol Chem
, vol.275
, pp. 322-327
-
-
Kharbanda, S.1
Saxena, S.2
Yoshida, K.3
Pandey, P.4
Kaneki, M.5
Wang, Q.6
Cheng, K.7
Chen, Y.N.8
Campbell, A.9
Sudha, T.10
Yuan, Z.M.11
Narula, J.12
Weichselbaum, R.13
Nalin, C.14
Kufe, D.15
-
15
-
-
0037230304
-
Activation of the jnk signaling pathway: Breaking the brake on apoptosis
-
Lin A: Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 2003;25:17-24.
-
(2003)
Bioessays
, vol.25
, pp. 17-24
-
-
Lin, A.1
-
16
-
-
77950339995
-
A model of ischemia and reperfusion increases jnk activity, inhibits the association of bad and 14-3-3, and induces apoptosis of rabbit spinal neurocytes
-
Fan J, Xu G, Nagel DJ, Hua Z, Zhang N, Yin G: A model of ischemia and reperfusion increases JNK activity, inhibits the association of BAD and 14-3-3, and induces apoptosis of rabbit spinal neurocytes. Neurosci Lett 2010;473:196-201.
-
(2010)
Neurosci Lett
, vol.473
, pp. 196-201
-
-
Fan, J.1
Xu, G.2
Nagel, D.J.3
Hua, Z.4
Zhang, N.5
Yin, G.6
-
17
-
-
0032538634
-
Brain-Derived neurotrophic factor induces rapid and transient release of glutamate through the non-Exocytotic pathway from cortical neurons
-
Takei N, Numakawa T, Kozaki S, Sakai N, Endo Y, Takahashi M, Hatanaka H: Brain-Derived neurotrophic factor induces rapid and transient release of glutamate through the non-Exocytotic pathway from cortical neurons. J Biol Chem 1998;273:27620-27624.
-
(1998)
J Biol Chem
, vol.273
, pp. 27620-27624
-
-
Takei, N.1
Numakawa, T.2
Kozaki, S.3
Sakai, N.4
Endo, Y.5
Takahashi, M.6
Hatanaka, H.7
-
18
-
-
0027328680
-
Combined oxygen and glucose deprivation in cortical cell culture: Calcium-Dependent and calcium-independent mechanisms of neuronal injury
-
Goldberg MP, Choi DW: Combined oxygen and glucose deprivation in cortical cell culture: calcium-Dependent and calcium-independent mechanisms of neuronal injury. J Neurosci 1993;13:3510-3524.
-
(1993)
J Neurosci
, vol.13
, pp. 3510-3524
-
-
Goldberg, M.P.1
Choi, D.W.2
-
19
-
-
79955620230
-
Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: Involvement of mitogen-Activated protein kinase pathway
-
Chen T, Liu W, Chao X, Qu Y, Zhang L, Luo P, Xie K, Huo J, Fei Z: Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: involvement of mitogen-Activated protein kinase pathway. Neuroscience 2011;183:203-211.
-
(2011)
Neuroscience
, vol.183
, pp. 203-211
-
-
Chen, T.1
Liu, W.2
Chao, X.3
Qu, Y.4
Zhang, L.5
Luo, P.6
Xie, K.7
Huo, J.8
Fei, Z.9
-
20
-
-
0027270211
-
Characterization of the cellular reduction of 3-( 4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide (mtt): Subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in mtt reduction
-
Berridge MV, Tan AS: Characterization of the cellular reduction of 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys 1993;303:474-482.
-
(1993)
Arch Biochem Biophys
, vol.303
, pp. 474-482
-
-
Berridge, M.V.1
Tan, A.S.2
-
21
-
-
84900901607
-
Hypoxia induces autophagy of bone marrow-Derived mesenchymal stem cells via activation of erk1/2
-
Wu J, Niu J, Li X, Li Y, Wang X, Lin J, Zhang F: Hypoxia induces autophagy of bone marrow-Derived mesenchymal stem cells via activation of ERK1/2. Cell Physiol Biochem 2014;33:1467-1474.
-
(2014)
Cell Physiol Biochem
, vol.33
, pp. 1467-1474
-
-
Wu, J.1
Niu, J.2
Li, X.3
Li, Y.4
Wang, X.5
Lin, J.6
Zhang, F.7
-
22
-
-
84948182665
-
Attenuating hypoxia-induced apoptosis and autophagy of mesenchymal stem cells: The potential of sitagliptin in stem cell-based therapy
-
Wang XM, Yang YJ, Wu YJ, Zhang Q, Qian HY: Attenuating Hypoxia-Induced Apoptosis and Autophagy of Mesenchymal Stem Cells: the Potential of Sitagliptin in Stem Cell-Based Therapy. Cell Physiol Biochem 2015;37:1914-1926.
-
(2015)
Cell Physiol Biochem
, vol.37
, pp. 1914-1926
-
-
Wang, X.M.1
Yang, Y.J.2
Wu, Y.J.3
Zhang, Q.4
Qian, H.Y.5
-
23
-
-
79951607477
-
Downregulation of autophagy by bcl-2 promotes mcf7 breast cancer cell growth independent of its inhibition of apoptosis
-
Oh S, Xiaofei E, Ni D, Pirooz SD, Lee JY, Lee D, Zhao Z, Lee S, Lee H, Ku B, Kowalik T, Martin SE, Oh BH, Jung JU, Liang C: Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis. Cell Death Differ 2011;18:452-464.
-
(2011)
Cell Death Differ
, vol.18
, pp. 452-464
-
-
Oh, S.1
Xiaofei, E.2
Ni, D.3
Pirooz, S.D.4
Lee, J.Y.5
Lee, D.6
Zhao, Z.7
Lee, S.8
Lee, H.9
Ku, B.10
Kowalik, T.11
Martin, S.E.12
Oh, B.H.13
Jung, J.U.14
Liang, C.15
-
24
-
-
34147168105
-
Distinct roles of autophagy in the heart during ischemia and reperfusion: Roles of amp-Activated protein kinase and beclin 1 in mediating autophagy
-
Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H, Asano T, Levine B, Sadoshima J: Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-Activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007;100:914-922.
-
(2007)
Circ Res
, vol.100
, pp. 914-922
-
-
Matsui, Y.1
Takagi, H.2
Qu, X.3
Abdellatif, M.4
Sakoda, H.5
Asano, T.6
Levine, B.7
Sadoshima, J.8
-
25
-
-
13844262643
-
The neuroprotective action of sp600125, a new inhibitor of jnk, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal ca1 via nuclear and non-nuclear pathways
-
Guan QH, Pei DS, Zhang QG, Hao ZB, Xu TL, Zhang GY: The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways. Brain Res 2005;1035:51-59.
-
(2005)
Brain Res
, vol.1035
, pp. 51-59
-
-
Guan, Q.H.1
Pei, D.S.2
Zhang, Q.G.3
Hao, Z.B.4
Xu, T.L.5
Zhang, G.Y.6
-
26
-
-
1842472069
-
Phosphorylation of bcl-2 regulates er ca2+ homeostasis and apoptosis
-
Bassik MC, Scorrano L, Oakes SA, Pozzan T, Korsmeyer SJ: Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis. EMBO J 2004;23:1207-1216.
-
(2004)
EMBO J
, vol.23
, pp. 1207-1216
-
-
Bassik, M.C.1
Scorrano, L.2
Oakes, S.A.3
Pozzan, T.4
Korsmeyer, S.J.5
-
27
-
-
15644381250
-
Bcl-2 undergoes phosphorylation by c-jun n-Terminal kinase/stress-Activated protein kinases in the presence of the constitutively active gtp-binding protein rac1
-
Maundrell K, Antonsson B, Magnenat E, Camps M, Muda M, Chabert C, Gillieron C, Boschert U, Vial-Knecht E, Martinou JC, Arkinstall S: Bcl-2 undergoes phosphorylation by c-Jun N-Terminal kinase/stress-Activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1. J Biol Chem 1997;272:25238-25242.
-
(1997)
J Biol Chem
, vol.272
, pp. 25238-25242
-
-
Maundrell, K.1
Antonsson, B.2
Magnenat, E.3
Camps, M.4
Muda, M.5
Chabert, C.6
Gillieron, C.7
Boschert, U.8
Vial-Knecht, E.9
Martinou, J.C.10
Arkinstall, S.11
-
28
-
-
0035968287
-
Jr: Novel role for jnk as a stress-Activated bcl2 kinase
-
Deng X, Xiao L, Lang W, Gao F, Ruvolo P, May WS, Jr: Novel role for JNK as a stress-Activated Bcl2 kinase. J Biol Chem 2001;276:23681-23688.
-
(2001)
J Biol Chem
, vol.276
, pp. 23681-23688
-
-
Deng, X.1
Xiao, L.2
Lang, W.3
Gao, F.4
Ruvolo, P.5
May, W.S.6
-
29
-
-
0037418238
-
JNK phosphorylation of bim-related members of the bcl2 family induces bax-Dependent apoptosis
-
Lei K, Davis RJ: JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-Dependent apoptosis. Proc Natl Acad Sci USA 2003;100:2432-2437.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2432-2437
-
-
Lei, K.1
Davis, R.J.2
-
30
-
-
50249189191
-
Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways
-
Wen YD, Sheng R, Zhang LS, Han R, Zhang X, Zhang XD, Han F, Fukunaga K, Qin ZH: Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways. Autophagy 2008;4:762-769.
-
(2008)
Autophagy
, vol.4
, pp. 762-769
-
-
Wen, Y.D.1
Sheng, R.2
Zhang, L.S.3
Han, R.4
Zhang, X.5
Zhang, X.D.6
Han, F.7
Fukunaga, K.8
Qin, Z.H.9
-
31
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, Mukherjee C, Shi Y, Gelinas C, Fan Y, Nelson DA, Jin S, White E: Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006;10:51-64.
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
Bray, K.4
Anderson, D.5
Chen, G.6
Mukherjee, C.7
Shi, Y.8
Gelinas, C.9
Fan, Y.10
Nelson, D.A.11
Jin, S.12
White, E.13
-
32
-
-
84945132432
-
MicroRNA-146a induced by hypoxia promotes chondrocyte autophagy through bcl-2
-
Zhang F, Wang J, Chu J, Yang C, Xiao H, Zhao C, Sun Z, Gao X, Chen G, Han Z, Zou W, Liu T: MicroRNA-146a Induced by Hypoxia Promotes Chondrocyte Autophagy through Bcl-2. Cell Physiol Biochem 2015;37:1442-1453.
-
(2015)
Cell Physiol Biochem
, vol.37
, pp. 1442-1453
-
-
Zhang, F.1
Wang, J.2
Chu, J.3
Yang, C.4
Xiao, H.5
Zhao, C.6
Sun, Z.7
Gao, X.8
Chen, G.9
Han, Z.10
Zou, W.11
Liu, T.12
|