Anti-inflammatory action of angiotensin 1-7 in experimental colitis

PLoS ONE

Volumn 11, Issue 3, 2016, Pages

  Khajah, Maitham A ^a   Fateel, Maryam M ^a   Ananthalakshmi, Kethireddy V ^a   Luqmani, Yunus A ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN [1-7]; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; ANTIINFLAMMATORY AGENT; DEXAMETHASONE; DEXTRAN SULFATE; DIPEPTIDYL CARBOXYPEPTIDASE; G PROTEIN COUPLED RECEPTOR; MAS 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; UNCLASSIFIED DRUG; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN I; ANGIOTENSIN I (1-7); ONCOPROTEIN; PEPTIDE FRAGMENT; PROTO-ONCOGENE PROTEINS C-MAS-1;

ADHESION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANORECTAL BLEEDING; ANORECTAL DISEASE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CLINICAL FEATURE; COLON; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; EDEMA; ERYTHEMA; EXPERIMENTAL COLITIS; FEMALE; LEUKOCYTE COUNT; MALE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECTUM HEMORRHAGE; TISSUE HOMOGENATE; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED; COLITIS; DISEASE MODEL; DRUG EFFECTS; METABOLISM; SIGNAL TRANSDUCTION;

ANGIOTENSIN I; ANIMALS; ANTI-INFLAMMATORY AGENTS; COLITIS; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84962592468     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0150861     Document Type: Article

References (56)

1. Fyhrquist F, Saijonmaa O. Renin-angiotensin system revisited. J Intern Med. 2008;264(3):224-36. doi: 10.1111/j.1365-2796.2008.01981.x PMID: 18793332
2. Geara AS, Azzi J, Jurewicz M, Abdi R. The renin-angiotensin system: an old, newly discovered player in immunoregulation. Transplant Rev. 2009;23(3):151-8.
3. Reudelhuber TL. The renin-angiotensin system: peptides and enzymes beyond angiotensin II. Curr Opin Nephrol Hypertens. 2005;14(2):155-9. PMID: 15687842
4. Jackson TR, Blair LA, Marshall J, Goedert M, Hanley MR. The mas oncogene encodes an angiotensin receptor. Nature. 1988;335(6189):437-40. PMID: 3419518
5. Santos RA, Ferreira AJ. Angiotensin-(1-7) and the renin-angiotensin system. Curr Opin Nephrol Hypertens. 2007;16(2):122-8. PMID: 17293687
6. Ferrario CM. Angiotensin I, angiotensin II and their biologically active peptides: J Hypertens. 2002 May; 20(5):805-7.; 2002. PMID: 12011630
7. Kucharewicz I, Pawlak R, Matys T, Chabielska E, Buczko W. Angiotensin-(1-7): an active memberof the renin-angiotensin system. J Physiol Pharmacol. 2002;53(4 Pt 1):533-40. PMID: 12512691
8. Iwai M, Horiuchi M. Devil and angel in the renin-angiotensin system: ACE-angiotensin II-AT1 receptor axis vs. ACE2-angiotensin-(1-7)-Mas receptor axis. Hypertens Res. 2009;32(7):533-6. doi: 10.1038/hr.2009.74 PMID: 19461648
9. Ferrario CM, Chappell MC, Tallant EA, Brosnihan KB, Diz DI. Counterregulatory actions of angiotensin-(1-7). Hypertension. 1997;30(3 Pt2):535-41. PMID: 9322978
10. Iyer SN, Chappell MC, Averill DB, Diz DI, Ferrario CM. Vasodepressor actions of angiotensin-(1-7) unmasked during combined treatment with lisinopril and losartan. Hypertension. 1998;31(2):699-705. PMID: 9461243
11. Iyer SN, Ferrario CM, Chappell MC. Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system. Hypertension. 1998;31(1 Pt2):356-61. PMID: 9453328
12. Luque M, Martin P, Martell N, Fernandez C, Brosnihan KB, Ferrario CM. Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) inessential hypertension. J Hypertens. 1996;14(6):799-805. PMID: 8793704
13. Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet. 2007;369(9573):1627-40. PMID: 17499605
14. Thoreson R, Cullen JJ. Pathophysiology of inflammatory bowel disease: an overview. Surg Clin North Am. 2007;87(3):575-85. PMID: 17560413
15. Mizushima T, Sasaki M, Ando T, Wada T, Tanaka M, Okamoto Y, et al. Blockage of angiotensin II type 1 receptor regulates TNF-alpha-induced MAdCAM-1 expression via inhibition of NF-kappaB translocation to the nucleus and ameliorates colitis. Am J Physiol Gastrointest Liver Physiol. 2009;298(2):25.
16. Jahovic N, Ercan F, Gedik N, Yuksel M, Sener G, Alican I. The effect of angiotensin-converting enzyme inhibitors on experimental colitis in rats. Regul Pept. 2005;130(1-2):67-74. PMID: 15908024
17. Spencer AU, Yang H, Haxhija EQ, Wildhaber BE, Greenson JK, Teitelbaum DH. Reduced severity of a mouse colitis model with angiotensin converting enzyme inhibition. Dig Dis Sci. 2007;52(4):1060-70. PMID: 17342403
18. Koga H, Yang H, Adler J, Zimmermann EM, Teitelbaum DH. Transanal delivery of angiotensin converting enzyme inhibitor prevents colonic fibrosis in a mouse colitis model: development of a unique mode of treatment. Surgery. 2008;144(2):259-68. doi: 10.1016/j.surg.2008.03.043 PMID: 18656634
19. Santiago OI, Rivera E, Ferder L, Appleyard CB. An angiotensin II receptor antagonist reduces inflammatory parameters in two models of colitis. Regul Pept. 2008;146(1-3):250-9. PMID: 18023891
20. Okawada M, Koga H, Larsen SD, Showalter HD, Turbiak AJ, Jin X, et al. Use of enterally delivered angiotensin II type Ia receptor antagonists to reduce the severity of colitis. Dig Dis Sci. 2011;56(9):2553-65. doi: 10.1007/s10620-011-1651-9 PMID: 21399927
21. Inokuchi Y, Morohashi T, Kawana I, Nagashima Y, Kihara M, Umemura S. Amelioration of 2, 4, 6-trinitrobenzene sulphonic acid induced colitis in angiotensinogen gene knockout mice. Gut. 2005;54(3):349-56. PMID: 15710982
22. Katada K, Yoshida N, Suzuki T, Okuda T, Mizushima K, Takagi T, et al. Dextran sulfate sodium-induced acute colonic inflammation in angiotensin II type 1a receptor deficient mice. Inflamm Res. 2008;57(2):84-91. doi: 10.1007/s00011-007-7098-y PMID: 18288458
23. Saibeni S, Spina L, Virgilio T, Folcioni A, Borsi G, de Franchis R, et al. Angiotensin-converting enzyme insertion/deletion gene polymorphism in inflammatory bowel diseases. Eur J Gastroenterol Hepatol. 2007;19(11):976-81. PMID: 18049167
24. Matsuda T, Suzuki J, Furuya K, Masutani M, Kawakami Y. Serum angiotensin I-converting enzyme is reduced in Crohn's disease and ulcerative colitis irrespective of genotype. Am J Gastroenterol. 2001;96(9):2705-10. PMID: 11569699
25. Sommer H, Schweisfurth H, Schulz M. Serum angiotensin-I-converting enzyme and carboxypeptidase N in Crohn's disease and ulcerative colitis. Enzyme. 1986;35(4):181-8. PMID: 3023044
26. Dong B, Zhang YH, Dong QL, Yu QT, Zhu L, Li SY, et al. [Overexpression of angiotensin converting enzyme 2 inhibits inflammatory response of atherosclerotic plaques in hypercholesterolemic rabbits]. ZhonghuaXin Xue Guan BingZaZhi. 2009;37(7):622-5. PMID: 19961735
27. da Silveira KD, Coelho FM, Vieira AT, Sachs D, Barroso LC, Costa VV, et al. Anti-inflammatory effects of the activation oftheangiotensin-(1-7) receptor, MAS, in experimental models of arthritis. J Immunol. 2010;185(9):5569-76. doi: 10.4049/jimmunol.1000314 PMID: 20935211
28. Tallant EA, Ferrario CM, Gallagher PE. Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor. Am J Physiol Heart Circ Physiol. 2005;289(4):10.
29. Su Z, Zimpelmann J, Burns KD. Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells. Kidney Int. 2006;69(12):2212-8. PMID: 16672906
30. Zhu Z, Zhong J, Zhu S, Liu D, Van Der Giet M, Tepel M. Angiotensin-(1-7) inhibits angiotensin II-induced signal transduction. J Cardiovasc Pharmacol. 2002;40(5):693-700. PMID: 12409978
31. Rebas E, Zabczynska J, Lachowicz A. The effect of angiotensin 1-7 on tyrosine kinases activity in rat anterior pituitary. Biochem Biophys Res Commun. 2006;347(3):581-5. PMID: 16842749
32. El-Hashim AZ, Renno WM, Raghupathy R, Abduo HT, Akhtar S, Benter IF. Angiotensin 1-7 inhibits allergic inflammation, via the Mas receptor, through suppression of ERK1/2 and NF-kappaB dependent pathways. Br J Pharmacol. 2012;2012(17):1476-5381.
33. Hamming I, Timens W, Bulthuis ML, Lely AT, Navis GJ, van Goor H. Tissue distribution of ACE2 protein, the functional receptorfor SARScoronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2004;203(2):631-7. PMID: 15141377
34. Harmer D, Gilbert M, Borman R, Clark KL. Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme. FEBS Lett. 2002;532(1-2):107-10. PMID: 12459472
35. Gembardt F, Sterner-Kock A, Imboden H, Spalteholz M, Reibitz F, Schultheiss HP, et al. Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents. Peptides. 2005;26(7):1270-7. PMID: 15949646
36. Wirtz S, Neufert C, Weigmann B, Neurath MF. Chemically induced mouse models of intestinal inflammation. Nat Protoc. 2007;2(3):541-6. PMID: 17406617
37. Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, et al. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm Bowel Dis. 2011;17(6):1359-72. doi: 10.1002/ibd.21478 PMID: 20872834
38. Beck PL, Li Y, Wong J, Chen CW, Keenan CM, Sharkey KA, et al. Inducible nitric oxide synthase from bone marrow-derived cells plays a critical role in regulating colonic inflammation. Gastroenterology. 2007;132(5):1778-90. Epub 2007/04/24. doi: S0016-5085 (07) 00167-9 [pii] 10.1053/j.gastro.2007.01.032. PMID: 17449036.
39. Garg M, Burrell LM, Velkoska E, Griggs K, Angus PW, Gibson PR, et al. Upregulation of circulating components of the alternative renin-angiotensin system in inflammatory bowel disease: A pilot study. J Renin Angiotensin Aldosterone Syst. 2015;16(3):559-69. doi: 10.1177/1470320314521086 PMID: 24505094
40. Gironacci MM, Fernandez-Tome Mdel C, Speziale E, Sterin-Speziale N, Pena C. Enhancement of phosphatidylcholine biosynthesis by angiotensin-(1-7) in the rat renal cortex. Biochem Pharmacol. 2002;63(3):507-14. PMID: 11853701
41. Muthalif MM, Benter IF, Uddin MR, Harper JL, Malik KU. Signal transduction mechanisms involved in angiotensin-(1-7)-stimulated arachidonic acid release and prostanoid synthesis in rabbit aortic smooth muscle cells. J Pharmacol ExpTher. 1998;284(1):388-98. PMID: 9435202
42. Wang Y, Qian C, Roks AJ, Westermann D, Schumacher SM, Escher F, et al. Circulating rather than cardiac angiotensin-(1-7) stimulates cardioprotection after myocardial infarction. Circ Heart Fail. 2010;3(2):286-93. doi: 10.1161/CIRCHEARTFAILURE.109.905968 PMID: 20103774
43. Gironacci MM, Adamo HP, Corradi G, Santos RA, Ortiz P, Carretero OA. Angiotensin (1-7) induces MAS receptor internalization. Hypertension. 2011;58(2):176-81. doi: 10.1161/HYPERTENSIONAHA. 111.173344 PMID: 21670420
44. Hommes D, van den Blink B, Plasse T, Bartelsman J, Xu C, Macpherson B, et al. Inhibition of stressactivated MAP kinases induces clinical improvement in moderate to severe Crohn's disease. Gastroenterology. 2002;122(1):7-14. PMID: 11781274
45. Jin X, Wang J, Xia ZM, Shang CH, Chao QL, Liu YR, et al. Anti-inflammatory and Anti-oxidative Activities of Paeonol and Its Metabolites Through Blocking MAPK/ERK/p38 Signaling Pathway. Inflammation. 2015;2015:3.
46. Peng XD, Wu XH, Chen LJ, Wang ZL, Hu XH, Song LF, et al. Inhibition of phosphoinositide 3-kinase ameliorates dextran sodium sulfate-induced colitis in mice. J Pharmacol Exp Ther. 2010;332(1):46-56. doi: 10.1124/jpet.109.153494 PMID: 19828878
47. Huang XL, Xu J, Zhang XH, Qiu BY, Peng L, Zhang M, et al. PI3K/Akt signaling pathway is involved in the pathogenesis of ulcerative colitis. Inflamm Res. 2011;60(8):727-34. doi: 10.1007/s00011-011-0325-6 PMID: 21442372
48. Byrnes JJ, Gross S, Ellard C, Connolly K, Donahue S, Picarella D. Effects of the ACE2 inhibitor GL1001 on acute dextran sodium sulfate-induced colitis in mice. Inflamm Res. 2009;58(11):819-27. doi: 10.1007/s00011-009-0053-3 PMID: 19517214
49. Vickers C, Hales P, Kaushik V, Dick L, Gavin J, Tang J, et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem. 2002;277(17):14838-43. PMID: 11815627
50. Hashimoto T, Perlot T, Rehman A, Trichereau J, Ishiguro H, Paolino M, et al. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature. 2012;487(7408):477-81. doi: 10. 1038/nature11228 PMID: 22837003
51. Zeng A, Dong K, Wang M, Sun J, Dong Y, Wang K, et al. Investigation of the colon-targeting, improvement on the side-effects and therapy on the experimental colitis in mouse of a resin microcapsule loading dexamethasone sodium phosphate. Drug Deliv. 2015;27:1-11.
52. Liu L, Yuan S, Long Y, Guo Z, Sun Y, Li Y, et al. Immunomodulation of Rheumtanguticum polysaccharide (RTP) on the immunosuppressive effects of dexamethasone (DEX) on the treatment of colitis in rats induced by 2, 4, 6-trinitrobenzene sulfonic acid. Int Immunopharmacol. 2009;9(13-14):1568-77. doi: 10.1016/j.intimp. 2009.09.013 PMID: 19788936
53. Kim I, Kong H, Lee Y, Hong S, Han J, Jung S, et al. Dexamethasone 21-sulfate improves the therapeutic properties of dexamethasone against experimental rat colitis by specifically delivering the steroid to the large intestine. Pharm Res. 2009;26(2):415-21. doi: 10.1007/s11095-008-9758-1 PMID: 18958401
54. van Meeteren ME, Meijssen MA, Zijlstra FJ. The effect of dexamethasone treatment on murine colitis. Scand J Gastroenterol. 2000;35(5):517-21. PMID: 10868455
55. Li L, Liu Z, Yang X, Yan H, Bao S, Fei J. Bioluminescence imaging for IL-1beta expression in experimental colitis. J Inflamm. 2013;10(1):1476-9255.
56. Al-Shamali A, Khan I. Expression of Na-H exchanger-8 isoform is suppressed in experimental colitis in adult rat: lack of reversibility by dexamethasone. Scand J Gastroenterol. 2011;46(1):20-9. doi: 10. 3109/00365521.2010.521890 PMID: 20950207