SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes

Molecular Cell

Volumn 61, Issue 6, 2016, Pages 859-873

  Kim, Jung Hyun ^a   Baddoo, Melody C ^b   Park, Eun Young ^a   Stone, Joshua K ^a   Park, Hyeonsoo ^a   Butler, Thomas W ^a   Huang, Gang ^c   Yan, Xiaomei ^c   Pauli Behn, Florencia ^d   Myers, Richard M ^d   Tan, Ming ^a   Flemington, Erik K ^b   Lim, Ssang Taek ^a   Ahn, Eun Young Erin ^a  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE LYSINE METHYLTRANSFERASE; ISOPROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN 1; MIXED LINEAGE LEUKEMIA PROTEIN 2; PROTEIN; PROTEIN MENIN; PROTEIN SON; UNCLASSIFIED DRUG; CHROMATIN; DNA BINDING PROTEIN; MEN1 PROTEIN, HUMAN; MINOR HISTOCOMPATIBILITY ANTIGEN; MLL PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN BINDING; SON PROTEIN, HUMAN;

ACUTE MYELOBLASTIC LEUKEMIA; ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BINDING SITE; BONE MARROW DERIVED MONONUCLEAR CELL; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; HEMATOPOIETIC CELL; HISTONE METHYLATION; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION INITIATION SITE; ACUTE MYELOID LEUKEMIA; BIOSYNTHESIS; CHROMATIN; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METHYLATION; PATHOLOGY; TUMOR CELL LINE;

ALTERNATIVE SPLICING; CELL LINE, TUMOR; CHROMATIN; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, LEUKEMIC; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; LEUKEMIA, MYELOID, ACUTE; METHYLATION; MINOR HISTOCOMPATIBILITY ANTIGENS; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PROTEIN BINDING; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84962571332     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.02.024     Document Type: Article

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