메뉴 건너뛰기




Volumn 48, Issue 5, 2016, Pages 2113-2123

MUC5B silencing reduces chemo-resistance of MCF-7 breast tumor cells and impairs maturation of dendritic cells

Author keywords

Cancer; Dendritic cells; MUC5B; Mucins

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MUCIN 5B; SHORT HAIRPIN RNA; CYTOKINE; MUC5B PROTEIN, HUMAN;

EID: 84962549713     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2016.3434     Document Type: Article
Times cited : (16)

References (45)
  • 1
    • 84911869642 scopus 로고    scopus 로고
    • Mucins: A biologically relevant glycan barrier in mucosal protection
    • Corfield AP: Mucins: A biologically relevant glycan barrier in mucosal protection. Biochim Biophys Acta 1850: 236-252, 2015.
    • (2015) Biochim Biophys Acta , vol.1850 , pp. 236-252
    • Corfield, A.P.1
  • 2
    • 70450247207 scopus 로고    scopus 로고
    • Mucins in cancer: Function, prognosis and therapy
    • Kufe DW: Mucins in cancer: Function, prognosis and therapy. Nat Rev Cancer 9: 874-885, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 874-885
    • Kufe, D.W.1
  • 3
    • 73349125438 scopus 로고    scopus 로고
    • Current status of mucins in the diagnosis and therapy of cancer
    • Rachagani S, Torres MP, Moniaux N and Batra SK: Current status of mucins in the diagnosis and therapy of cancer. Biofactors 35: 509-527, 2009.
    • (2009) Biofactors , vol.35 , pp. 509-527
    • Rachagani, S.1    Torres, M.P.2    Moniaux, N.3    Batra, S.K.4
  • 6
    • 84870931422 scopus 로고    scopus 로고
    • MUC1 immunotherapy is here to stay
    • Kimura T and Finn OJ: MUC1 immunotherapy is here to stay. Expert Opin Biol Ther 13: 35-49, 2013.
    • (2013) Expert Opin Biol Ther , vol.13 , pp. 35-49
    • Kimura, T.1    Finn, O.J.2
  • 7
    • 84898022102 scopus 로고    scopus 로고
    • Altered tumor-cell glycosylation promotes metastasis
    • H äuselmann I and Borsig L: Altered tumor-cell glycosylation promotes metastasis. Front Oncol 4: 28, 2014.
    • (2014) Front Oncol , vol.4 , pp. 28
    • Häuselmann, I.1    Borsig, L.2
  • 9
    • 66149143976 scopus 로고    scopus 로고
    • The membrane mucin Muc4 inhibits apoptosis induced by multiple insults via ErbB2-dependent and ErbB2-independent mechanisms
    • Workman HC, Sweeney C and Carraway KL III: The membrane mucin Muc4 inhibits apoptosis induced by multiple insults via ErbB2-dependent and ErbB2-independent mechanisms. Cancer Res 69: 2845-2852, 2009.
    • (2009) Cancer Res , vol.69 , pp. 2845-2852
    • Workman, H.C.1    Sweeney, C.2    Carraway, K.L.3
  • 10
    • 84866995203 scopus 로고    scopus 로고
    • MUC5B leads to aggressive behavior of breast cancer MCF7 cells
    • Valque H, Gouyer V, Gottrand F and Desseyn JL: MUC5B leads to aggressive behavior of breast cancer MCF7 cells. PLoS One 7: e46699, 2012.
    • (2012) PLoS One , vol.7 , pp. e46699
    • Valque, H.1    Gouyer, V.2    Gottrand, F.3    Desseyn, J.L.4
  • 12
    • 77952452039 scopus 로고    scopus 로고
    • RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells
    • Yamazoe S, Tanaka H, Sawada T, Amano R, Yamada N, Ohira M and Hirakawa K: RNA interference suppression of mucin 5AC (MUC5AC) reduces the adhesive and invasive capacity of human pancreatic cancer cells. J Exp Clin Cancer Res 29: 53, 2010.
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 53
    • Yamazoe, S.1    Tanaka, H.2    Sawada, T.3    Amano, R.4    Yamada, N.5    Ohira, M.6    Hirakawa, K.7
  • 14
    • 79956000989 scopus 로고    scopus 로고
    • Mucin 13: Structure, function, and potential roles in cancer pathogenesis
    • Maher DM, Gupta BK, Nagata S, Jaggi M and Chauhan SC: Mucin 13: Structure, function, and potential roles in cancer pathogenesis. Mol Cancer Res 9: 531-537, 2011.
    • (2011) Mol Cancer Res , vol.9 , pp. 531-537
    • Maher, D.M.1    Gupta, B.K.2    Nagata, S.3    Jaggi, M.4    Chauhan, S.C.5
  • 15
    • 84857118144 scopus 로고    scopus 로고
    • MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells
    • Lakshmanan I, Ponnusamy MP, Das S, Chakraborty S, Haridas D, Mukhopadhyay P, Lele SM and Batra SK: MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells. Oncogene 31: 805-817, 2012.
    • (2012) Oncogene , vol.31 , pp. 805-817
    • Lakshmanan, I.1    Ponnusamy, M.P.2    Das, S.3    Chakraborty, S.4    Haridas, D.5    Mukhopadhyay, P.6    Lele, S.M.7    Batra, S.K.8
  • 16
    • 51549099068 scopus 로고    scopus 로고
    • MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma
    • Tinder TL, Subramani DB, Basu GD, Bradley JM, Schettini J, Million A, Skaar T and Mukherjee P: MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma. J Immunol 181: 3116-3125, 2008.
    • (2008) J Immunol , vol.181 , pp. 3116-3125
    • Tinder, T.L.1    Subramani, D.B.2    Basu, G.D.3    Bradley, J.M.4    Schettini, J.5    Million, A.6    Skaar, T.7    Mukherjee, P.8
  • 18
    • 84857793524 scopus 로고    scopus 로고
    • Decisions about dendritic cells: Past, present, and future
    • Steinman RM: Decisions about dendritic cells: Past, present, and future. Annu Rev Immunol 30: 1-22, 2012.
    • (2012) Annu Rev Immunol , vol.30 , pp. 1-22
    • Steinman, R.M.1
  • 19
    • 22544457164 scopus 로고    scopus 로고
    • Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity
    • Carlos CA, Dong HF, Howard OM, Oppenheim JJ, Hanisch FG and Finn OJ: Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity. J Immunol 175: 1628-1635, 2005.
    • (2005) J Immunol , vol.175 , pp. 1628-1635
    • Carlos, C.A.1    Dong, H.F.2    Howard, O.M.3    Oppenheim, J.J.4    Hanisch, F.G.5    Finn, O.J.6
  • 21
    • 0034292388 scopus 로고    scopus 로고
    • The mechanism of unresponsiveness to circulating tumor antigen MUC1 is a block in intracellular sorting and processing by dendritic cells
    • H iltbold EM, Vlad AM, Ciborowski P, Watkins SC and Finn OJ: The mechanism of unresponsiveness to circulating tumor antigen MUC1 is a block in intracellular sorting and processing by dendritic cells. J Immunol 165: 3730-3741, 2000.
    • (2000) J Immunol , vol.165 , pp. 3730-3741
    • Hiltbold, E.M.1    Vlad, A.M.2    Ciborowski, P.3    Watkins, S.C.4    Finn, O.J.5
  • 23
    • 79953155667 scopus 로고    scopus 로고
    • Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses
    • Freire T, Lo-Man R, Bay S and Leclerc C: Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses. J Biol Chem 286: 7797-7811, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 7797-7811
    • Freire, T.1    Lo-Man, R.2    Bay, S.3    Leclerc, C.4
  • 25
    • 33745177351 scopus 로고    scopus 로고
    • Regulation of mucin expression: Mechanistic aspects and implications for cancer and inflammatory diseases
    • Andrianifahanana M, Moniaux N and Batra SK: Regulation of mucin expression: Mechanistic aspects and implications for cancer and inflammatory diseases. Biochim Biophys Acta 1765: 189-222, 2006.
    • (2006) Biochim Biophys Acta , vol.1765 , pp. 189-222
    • Andrianifahanana, M.1    Moniaux, N.2    Batra, S.K.3
  • 28
    • 0033636813 scopus 로고    scopus 로고
    • Developmental mucin gene expression in the gastroduodenal tract and accessory digestive glands. II. Duodenum and liver, gallbladder, and pancreas
    • Buisine MP, Devisme L, Degand P, Dieu MC, Gosselin B, Copin MC, Aubert JP and Porchet N: Developmental mucin gene expression in the gastroduodenal tract and accessory digestive glands. II. Duodenum and liver, gallbladder, and pancreas. J Histochem Cytochem 48: 1667-1676, 2000.
    • (2000) J Histochem Cytochem , vol.48 , pp. 1667-1676
    • Buisine, M.P.1    Devisme, L.2    Degand, P.3    Dieu, M.C.4    Gosselin, B.5    Copin, M.C.6    Aubert, J.P.7    Porchet, N.8
  • 31
    • 84865576848 scopus 로고    scopus 로고
    • Human monocyte-derived dendritic cells from leukoreduction system chambers after plateletpheresis are functional in an in vitro co-culture assay with intestinal epithelial cells
    • Tiscornia I, Sánchez-Martins V, Hernández A and Bollati-Fogolín M: Human monocyte-derived dendritic cells from leukoreduction system chambers after plateletpheresis are functional in an in vitro co-culture assay with intestinal epithelial cells. J Immunol Methods 384: 164-170, 2012.
    • (2012) J Immunol Methods , vol.384 , pp. 164-170
    • Tiscornia, I.1    Sánchez-Martins, V.2    Hernández, A.3    Bollati-Fogolín, M.4
  • 32
    • 84883209992 scopus 로고    scopus 로고
    • Cancer cells acquire resistance to anticancer drugs: An update
    • Lu HP and Chao CC: Cancer cells acquire resistance to anticancer drugs: An update. Biomed J 35: 464-472, 2012.
    • (2012) Biomed J , vol.35 , pp. 464-472
    • Lu, H.P.1    Chao, C.C.2
  • 35
    • 69449102415 scopus 로고    scopus 로고
    • Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment
    • Pandit TS, Kennette W, Mackenzie L, Zhang G, Al-Katib W, Andrews J, Vantyghem SA, Ormond DG, Allan AL, Rodenhiser DI, et al: Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment. Int J Oncol 35: 297-308, 2009.
    • (2009) Int J Oncol , vol.35 , pp. 297-308
    • Pandit, T.S.1    Kennette, W.2    Mackenzie, L.3    Zhang, G.4    Al-Katib, W.5    Andrews, J.6    Vantyghem, S.A.7    Ormond, D.G.8    Allan, A.L.9    Rodenhiser, D.I.10
  • 36
    • 77950828177 scopus 로고    scopus 로고
    • MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies
    • Mimeault M, Johansson SL, Senapati S, Momi N, Chakraborty S and Batra SK: MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies. Cancer Lett 295: 69-84, 2010.
    • (2010) Cancer Lett , vol.295 , pp. 69-84
    • Mimeault, M.1    Johansson, S.L.2    Senapati, S.3    Momi, N.4    Chakraborty, S.5    Batra, S.K.6
  • 37
    • 34948826922 scopus 로고    scopus 로고
    • Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: Overcoming cellular barriers for therapeutic gain
    • Kalra AV and Campbell RB: Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: Overcoming cellular barriers for therapeutic gain. Br J Cancer 97: 910-918, 2007.
    • (2007) Br J Cancer , vol.97 , pp. 910-918
    • Kalra, A.V.1    Campbell, R.B.2
  • 40
    • 84875887000 scopus 로고    scopus 로고
    • The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family
    • Skrypek N, Duchêne B, Hebbar M, Leteurtre E, van Seuningen I and Jonckheere N: The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family. Oncogene 32: 1714-1723, 2013.
    • (2013) Oncogene , vol.32 , pp. 1714-1723
    • Skrypek, N.1    Duchêne, B.2    Hebbar, M.3    Leteurtre, E.4    Van Seuningen, I.5    Jonckheere, N.6
  • 41
    • 57649171078 scopus 로고    scopus 로고
    • Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours
    • Kalra AV and Campbell RB: Mucin overexpression limits the effectiveness of 5-FU by reducing intracellular drug uptake and antineoplastic drug effects in pancreatic tumours. Eur J Cancer 45: 164-173, 2009.
    • (2009) Eur J Cancer , vol.45 , pp. 164-173
    • Kalra, A.V.1    Campbell, R.B.2
  • 45
    • 84864597970 scopus 로고    scopus 로고
    • The sweet side of tumor immunotherapy
    • Freire T and Osinaga E: The sweet side of tumor immunotherapy. Immunotherapy 4: 719-734, 2012.
    • (2012) Immunotherapy , vol.4 , pp. 719-734
    • Freire, T.1    Osinaga, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.