The good neighbor coping with insulin resistance by modulating adipose tissue endothelial cell function

Circulation Research

Volumn 118, Issue 5, 2016, Pages 776-778

  Yar, Sumeyye ^a   Chang, Hsiang Chun ^a   Ardehali, Hossein ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL FAT; ADIPOCYTE; ADIPOSE TISSUE; ADIPOSE TISSUE ENDOTHELIAL CELL; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CELL FUNCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; ENDOTHELIUM CELL; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; MACROPHAGE; MONOCYTE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PREVALENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; RISK FACTOR; SIGNAL TRANSDUCTION; WHITE ADIPOSE TISSUE; ANIMAL; BIOSYNTHESIS; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; MALE; METABOLISM; PHYSIOLOGY;

GLUCOSE BLOOD LEVEL; MICRORNA;

ADIPOSE TISSUE, WHITE; ANIMALS; BLOOD GLUCOSE; ENDOTHELIAL CELLS; HOMEOSTASIS; HUMANS; INSULIN RESISTANCE; MALE; MICRORNAS;

EID: 84962508081     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.308338     Document Type: Review

References (19)

1. Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA. 2014;311:806-814. doi: 10.1001/jama.2014.732.
2. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259:87-91.
3. Paneni F, Costantino S, Cosentino F. Insulin resistance, diabetes, and cardiovascular risk. Curr Atheroscler Rep. 2014;16:419. doi: 10.1007/s11883-014-0419-z.
4. Odegaard JI, Chawla A. Pleiotropic actions of insulin resistance and in-fammation in metabolic homeostasis. Science. 2013;339:172-177. doi: 10.1126/science.1230721.
5. Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H. Chronic infammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003;112:1821-1830. doi: 10.1172/JCI19451.
6. Huber B, Volz AC, Kluger PJ. Understanding the effects of mature adi-pocytes and endothelial cells on fatty acid metabolism and vascular tone in physiological fatty tissue for vascularized adipose tissue engineering. Cell Tissue Res. 2015;362:269-279. doi: 10.1007/s00441-015-2274-9.
7. Tabit CE, Chung WB, Hamburg NM, Vita JA. Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications. Rev Endocr Metab Disord. 2010;11:61-74. doi: 10.1007/s11154-010-9134-4.
8. Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation. 2006;113:1888-1904. doi: 10.1161/CIRCULATIONAHA.105.563213.
9. Arner P, Kulyté A. MicroRNA regulatory networks in human adipose tissue and obesity. Nat Rev Endocrinol. 2015;11:276-288. doi: 10.1038/nrendo.2015.25.
10. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259:87-91.
11. Chen L, Chen R, Wang H, Liang FX. Mechanisms linking infamma-tion to insulin resistance. Int J Endocrinol. 2015;2015:508409. doi: 10.1155/2015/508409.
12. Herman AG, Moncada S. Therapeutic potential of nitric oxide donors in the prevention and treatment of atherosclerosis. Eur Heart J. 2005;26:1945-1955. doi: 10.1093/eurheartj/ehi333.
13. Villaret A, Galitzky J, Decaunes P, Estève D, Marques MA, Sengenès C, Chiotasso P, Tchkonia T, Lafontan M, Kirkland JL, Bouloumié A. Adipose tissue endothelial cells from obese human subjects: differences among depots in angiogenic, metabolic, and infammatory gene expression and cellular senescence. Diabetes. 2010;59:2755-2763. doi: 10.2337/db10-0398.
14. Kralisch S, Sommer G, Stangl V, Köhler U, Kratzsch J, Stepan H, Faber R, Schubert A, Lössner U, Vietzke A, Bluher M, Stumvoll M, Fasshauer M. Secretory products from human adipocytes impair endothelial function via nuclear factor kappaB. Atherosclerosis. 2008;196:523-531. doi: 10.1016/j.atherosclerosis.2007.05.016.
15. Zhang H, Zhang C. Regulation of microvascular Function by adipose tissue in obesity and type 2 diabetes: evidence of an adipose-vascular loop. Am J Biomed Sci. 2009;1:133.
16. Pellegrinelli V, Rouault C, Veyrie N, Clément K, Lacasa D. Endothelial cells from visceral adipose tissue disrupt adipocyte functions in a three-dimensional setting: partial rescue by angiopoietin-1. Diabetes. 2014;63:535-549. doi: 10.2337/db13-0537.
17. Sun X, Sit A, Feinberg MW. Role of miR-181 family in regulating vascular infammation and immunity. Trends Cardiovasc Med. 2014;24:105-112. doi: 10.1016/j.tcm.2013.09.002.
18. Sun X, He S, Wara AK, Icli B, Shvartz E, Tesmenitsky Y, Belkin N, Li D, Blackwell TS, Sukhova GK, Croce K, Feinberg MW. Systemic delivery of microRNA-181b inhibits nuclear factor-κB activation, vascular infammation, and atherosclerosis in apolipoprotein E-defcient mice. Circ Res. 2014;114:32-40. doi: 10.1161/CIRCRESAHA.113.302089.
19. Sun X, Lin J, Zhang Y, Kang S, Belkin N, Wara AK, Icli B, Hamburg NM, Li D, Feinberg MW. MicroRNA-181b improves glucose homeostasis and insulin sensitivity by regulating endothelial function in white adipose tissue. Circ Res. 2016;118:810-821. doi: 10.1161/CIRCRESAHA.115.308166.