Association of neurotrophins, inflammation and stress with suicide risk in young adults

Clinica Chimica Acta

Volumn 457, Issue , 2016, Pages 41-45

  Priya, P Kaviya ^a   Rajappa, Medha ^a   Kattimani, Shivanand ^a   Mohanraj, P S ^a   Revathy, G ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Cholesterol; High sensitivity C reactive protein; Interleukin 6; Neurotrophins; Stress; Suicide; Suicide predictors

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; C REACTIVE PROTEIN; INTERLEUKIN 6; NEUROTROPHIN 3; NERVE GROWTH FACTOR;

ADULT; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DAILY HASSLES AND UPLIFTS SCALE REVISED; DISEASE ASSOCIATION; DISEASE SEVERITY; DISTRESS SYNDROME; FEMALE; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; INFLAMMATION; LIFE EVENTS SCALE; MALE; MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW; PATHOGENESIS; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; STRESS; STRESS ASSESSMENT; SUICIDE ATTEMPT; ADOLESCENT; BLOOD; COMPLICATION; MENTAL STRESS; METABOLISM; RISK FACTOR; SUICIDE;

ADOLESCENT; ADULT; C-REACTIVE PROTEIN; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INFLAMMATION; MALE; NERVE GROWTH FACTORS; RISK FACTORS; STRESS, PSYCHOLOGICAL; SUICIDE;

EID: 84962469191     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2016.03.019     Document Type: Article

References (29)

1. Accidental Deaths and Suicides in India 2012, New Delhi: Ministry of Home Affairs, Govt. of India, National Crime Record Bureau. ncrb.gov.in/CD-ADSI-2012/ADSI2012.pdf.
2. Huang E.J., Reichardt L.F. Neurotrophins: roles in neuronal development and function. Annu. Rev. Neurosci. 2001, 24:677-736.
3. Sher L. Brain-derived neurotrophic factor and suicidal behavior in adolescents. World J. Pediatr. 2011, 7:197-198.
4. Pae C.U., Marks D.M., Han C., Patkar A.A., Steffens D. Does neurotropin-3 have a therapeutic implication in major depression?. Int. J. Neurosci. 2008, 118:1515-1522.
5. Fuligni A.J., Telzer E.H., Bower J., Cole S.W., Kiang L., Irwin M.R. A preliminary study of daily interpersonal stress and C-reactive protein levels among adolescents from Latin American and European backgrounds. Psychosom. Med. 2009, 71:329-333.
6. Steiner J., Bielau H., Brisch R., Danos P., Ullrich O., Mawrin C., et al. Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide. J. Psychiatr. Res. 2008, 42:151-157.
7. Engelberg H. Low serum cholesterol and suicide. Lancet 1992, 339:727-729.
8. Vevera J., Fisar Z., Kvasnicka T., Zdenek H., Starkova L., Ceska R., et al. Cholesterol-lowering therapy evokes time-limited changes in serotonergic transmission. Psychiatry Res. 2005, 133:197-203.
9. Bhatia M.S., Aggarwal N.K., Aggarwal B.B. Psychosocial profile of suicide ideators, attempters and completers in India. Int. J. Soc. Psychiatry 2000, 46:155-163.
10. Kim Y.K., Lee H.P., Won S.D., Park E.Y., Lee H.Y., Lee B.H., et al. Low plasma BDNF is associated with suicidal behavior in major depression. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2007, 31:78-85.
11. Singh G., Kaur D., Kaur H. Presumptive stressful life events scale (psles) - a new stressful life events scale for use in India. Indian J. Psychiatry 1984, 26:107-114.
12. Kanner A.D., Coyne J.C., Schaefer C., Lazarus R.S. Comparison of two modes of stress measurement: daily hassles and uplifts versus major life events. J. Behav. Med. 1981, 4:1-39.
13. Bjelland I., Dahl A.A., Haug T.T., Neckelmann D. The validity of the hospital anxiety and depression scale. An updated literature review. J. Psychosom. Res. 2002, 52:69-77.
14. Sheehan D.V., Lecrubier Y., Sheehan K.H., Amorim P., Janavs J., Weiller E., et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry. 1998, 59(Suppl. 20):22-33. (quiz 34-57).
15. Karege F., Vaudan G., Schwald M., Perroud N., La Harpe R. Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain Res. Mol. Brain Res. 2005, 136:29-37.
16. Pallavi P., Sagar R., Mehta M., Sharma S., Subramanium A., Shamshi F., et al. Serum neurotrophic factors in adolescent depression: gender difference and correlation with clinical severity. J. Affect. Disord. 2013, 150:415-423.
17. Duman R.S., Malberg J., Nakagawa S., D'Sa C. Neuronal plasticity and survival in mood disorders. Biol. Psychiatry 2000, 48:732-739.
18. Garcia R. Stress, synaptic plasticity, and psychopathology. Rev. Neurosci. 2002, 13:195-208.
19. Dawood T., Anderson J., Barton D., Lambert E., Esler M., Hotchkin E., et al. Reduced overflow of BDNF from the brain is linked with suicide risk in depressive illness. Mol. Psychiatry 2007, 12:981-983.
20. Lee B.H., Kim Y.K. The roles of BDNF in the pathophysiology of major depression and in antidepressant treatment. Psychiatry Investig. 2010, 7:231-235.
21. Satomura E., Baba H., Nakano Y., Maeshima H., Suzuki T., Arai H. Correlations between brain-derived neurotrophic factor and clinical symptoms in medicated patients with major depression. J. Affect. Disord. 2011, 135:332-335.
22. Wium-Andersen M.K., Orsted D.D., Nielsen S.F., Nordestgaard B.G. Elevated C-reactive protein levels, psychological distress, and depression in 73,131 individuals. JAMA Psychiatry 2013, 70:176-184.
23. O'Donovan A., Rush G., Hoatam G., Hughes B.M., McCrohan A., Kelleher C., et al. Suicidal ideation is associated with elevated inflammation in patients with major depressive disorder. Depress. Anxiety 2013, 30:307-314.
24. Puustinen P.J., Koponen H., Kautiainen H., Mantyselka P., Vanhala M. Psychological distress and C-reactive protein: do health behaviours and pathophysiological factors modify the association?. Eur. Arch. Psychiatry Clin. Neurosci. 2011, 261:277-284.
25. Kim Y.K., Lee S.W., Kim S.H., Shim S.H., Han S.W., Choi S.H., et al. Differences in cytokines between non-suicidal patients and suicidal patients in major depression. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2008, 32:356-361.
26. Lindqvist D., Janelidze S., Hagell P., Erhardt S., Samuelsson M., Minthon L., et al. Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity. Biol. Psychiatry 2009, 66:287-292.
27. Ruljancic N., Mihanovic M., Cepelak I. Thrombocyte serotonin and serum cholesterol concentration in suicidal and non-suicidal depressed patients. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2011, 35:1261-1267.
28. Marcinko D., Pivac N., Martinac M., Jakovljevic M., Mihaljevic-Peles A., Muck-Seler D. Platelet serotonin and serum cholesterol concentrations in suicidal and non-suicidal male patients with a first episode of psychosis. Psychiatry Res. 2007, 150:105-108.
29. da Graca Cantarelli M., Nardin P., Buffon A., Eidt M.C., Antonio Godoy L., Fernandes B.S., et al. Serum triglycerides, but not cholesterol or leptin, are decreased in suicide attempters with mood disorders. J. Affect. Disord. 2014, 172C:403-409.