-
1
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
1:CAS:528:DC%2BC3cXhtVCrtrbN 20525992 3549297
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711-23.
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
-
2
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
1:CAS:528:DC%2BC38XhtV2rs7fN 22658127 3544539
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26):2443-54.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
-
3
-
-
84932628341
-
PD-1 blockade in tumors with mismatch-repair deficiency
-
1:CAS:528:DC%2BC2MXhtFyrsbrI 26028255
-
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med. 2015;372(26):2509-20.
-
(2015)
N Engl J Med
, vol.372
, Issue.26
, pp. 2509-2520
-
-
Le, D.T.1
Uram, J.N.2
Wang, H.3
Bartlett, B.R.4
Kemberling, H.5
Eyring, A.D.6
Skora, A.D.7
Luber, B.S.8
Azad, N.S.9
Laheru, D.10
-
4
-
-
84925221855
-
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
-
25482239 4348009
-
Ansell SM, Lesokhin AM, Borrello I, Halwani A, Scott EC, Gutierrez M, Schuster SJ, Millenson MM, Cattry D, Freeman GJ. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med. 2015;372(4):311-9.
-
(2015)
N Engl J Med
, vol.372
, Issue.4
, pp. 311-319
-
-
Ansell, S.M.1
Lesokhin, A.M.2
Borrello, I.3
Halwani, A.4
Scott, E.C.5
Gutierrez, M.6
Schuster, S.J.7
Millenson, M.M.8
Cattry, D.9
Freeman, G.J.10
-
5
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
1:CAS:528:DC%2BC2MXht12qu7%2FJ 26028407
-
Brahmer J, Reckamp KL, Baas P, Crino L, Eberhardt WE, Poddubskaya E, Antonia S, Pluzanski A, Vokes EE, Holgado E. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med. 2015;373(2):123-35.
-
(2015)
N Engl J Med
, vol.373
, Issue.2
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crino, L.4
Eberhardt, W.E.5
Poddubskaya, E.6
Antonia, S.7
Pluzanski, A.8
Vokes, E.E.9
Holgado, E.10
-
6
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
1:CAS:528:DC%2BC2MXht12isr7M 26027431
-
Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, Schadendorf D, Dummer R, Smylie M, Rutkowski P. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med. 2015;373(1):23-34.
-
(2015)
N Engl J Med
, vol.373
, Issue.1
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
Grob, J.J.4
Cowey, C.L.5
Lao, C.D.6
Schadendorf, D.7
Dummer, R.8
Smylie, M.9
Rutkowski, P.10
-
7
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
1:CAS:528:DC%2BC38XhtV2rsbnJ 22658128 3563263
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366(26):2455-65.
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
-
8
-
-
0037422027
-
Hereditary colorectal cancer
-
1:CAS:528:DC%2BD3sXhvVOit7s%3D 12621137
-
Lynch HT, de la Chapelle A. Hereditary colorectal cancer. N Engl J Med. 2003;348(10):919-32.
-
(2003)
N Engl J Med
, vol.348
, Issue.10
, pp. 919-932
-
-
Lynch, H.T.1
De La Chapelle, A.2
-
9
-
-
84922369377
-
The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints
-
1:CAS:528:DC%2BC2MXhtFCntbo%3D 25358689 4293246
-
Llosa NJ, Cruise M, Tam A, Wicks EC, Hechenbleikner EM, Taube JM, Blosser RL, Fan H, Wang H, Luber BS. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer discovery. 2015;5(1):43-51.
-
(2015)
Cancer Discovery
, vol.5
, Issue.1
, pp. 43-51
-
-
Llosa, N.J.1
Cruise, M.2
Tam, A.3
Wicks, E.C.4
Hechenbleikner, E.M.5
Taube, J.M.6
Blosser, R.L.7
Fan, H.8
Wang, H.9
Luber, B.S.10
-
10
-
-
0028276666
-
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
-
1:CAS:528:DyaK2cXlsFCns78%3D 8030745 1887287
-
Kim H, Jen J, Vogelstein B, Hamilton SR. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol. 1994;145(1):148-56.
-
(1994)
Am J Pathol
, vol.145
, Issue.1
, pp. 148-156
-
-
Kim, H.1
Jen, J.2
Vogelstein, B.3
Hamilton, S.R.4
-
11
-
-
38449109687
-
Central HER2 IHC and FISH analysis in a trastuzumab (Herceptin) phase II monotherapy study: Assessment of test sensitivity and impact of chromosome 17 polysomy
-
1:CAS:528:DC%2BD1cXitlWlsbg%3D 17412870
-
Hofmann M, Stoss O, Gaiser T, Kneitz H, Heinmoller P, Gutjahr T, Kaufmann M, Henkel T, Ruschoff J. Central HER2 IHC and FISH analysis in a trastuzumab (Herceptin) phase II monotherapy study: assessment of test sensitivity and impact of chromosome 17 polysomy. Journal of clinical pathology. 2008;61(1):89-94.
-
(2008)
Journal of Clinical Pathology
, vol.61
, Issue.1
, pp. 89-94
-
-
Hofmann, M.1
Stoss, O.2
Gaiser, T.3
Kneitz, H.4
Heinmoller, P.5
Gutjahr, T.6
Kaufmann, M.7
Henkel, T.8
Ruschoff, J.9
-
12
-
-
84922017795
-
Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma
-
1:CAS:528:DC%2BC2MXjvFWrt7o%3D 25081749
-
Tsai JH, Lin YL, Cheng YC, Chen CC, Lin LI, Tseng LH, Cheng ML, Liau JY, Jeng YM. Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma. Modern pathology. 2015;28(2):268-78.
-
(2015)
Modern Pathology
, vol.28
, Issue.2
, pp. 268-278
-
-
Tsai, J.H.1
Lin, Y.L.2
Cheng, Y.C.3
Chen, C.C.4
Lin, L.I.5
Tseng, L.H.6
Cheng, M.L.7
Liau, J.Y.8
Jeng, Y.M.9
-
13
-
-
84885083538
-
B7-H1 expression is associated with poor prognosis in colorectal carcinoma and regulates the proliferation and invasion of HCT116 colorectal cancer cells
-
1:CAS:528:DC%2BC3sXhsF2rsr3L 24124529 3790819
-
Shi SJ, Wang LJ, Wang GD, Guo ZY, Wei M, Meng YL, Yang AG, Wen WH. B7-H1 expression is associated with poor prognosis in colorectal carcinoma and regulates the proliferation and invasion of HCT116 colorectal cancer cells. PLoS One. 2013;8(10):e76012.
-
(2013)
PLoS One
, vol.8
, Issue.10
, pp. e76012
-
-
Shi, S.J.1
Wang, L.J.2
Wang, G.D.3
Guo, Z.Y.4
Wei, M.5
Meng, Y.L.6
Yang, A.G.7
Wen, W.H.8
-
14
-
-
84937041504
-
Relationship between PD-L1 expression and clinical outcomes in patients with advanced gastric cancer treated with the anti-PD-1 monoclonal antibody pembrolizumab (MK-3475)
-
KEYNOTE-012. (suppl; abstr 4001)
-
Bang YJ, Shankaran V, Geva R, Yang AG, Wen WH. Relationship between PD-L1 expression and clinical outcomes in patients with advanced gastric cancer treated with the anti-PD-1 monoclonal antibody pembrolizumab (MK-3475) in KEYNOTE-012. J Clin Oncol. 2015;33(suppl; abstr 4001).
-
(2015)
J Clin Oncol.
, pp. 33
-
-
Bang, Y.J.1
Shankaran, V.2
Geva, R.3
Yang, A.G.4
Wen, W.H.5
-
15
-
-
84907270779
-
Comprehensive molecular characterization of gastric adenocarcinoma
-
Cancer Genome Atlas Research N
-
Cancer Genome Atlas Research N. Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 2014;513(7517):202-9.
-
(2014)
Nature
, vol.513
, Issue.7517
, pp. 202-209
-
-
-
16
-
-
84942930520
-
Loss of ARID1A expression in gastric cancer: Correlation with mismatch repair deficiency and clinicopathologic features
-
26468418 4604335
-
Kim KJ, Jung HY, Oh MH, Cho H, Lee JH, Lee HJ, Jang SH, Lee MS. Loss of ARID1A expression in gastric cancer: correlation with mismatch repair deficiency and clinicopathologic features. Journal of gastric cancer. 2015;15(3):201-8.
-
(2015)
Journal of Gastric Cancer
, vol.15
, Issue.3
, pp. 201-208
-
-
Kim, K.J.1
Jung, H.Y.2
Oh, M.H.3
Cho, H.4
Lee, J.H.5
Lee, H.J.6
Jang, S.H.7
Lee, M.S.8
-
17
-
-
84876499666
-
KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: Results from a large international multicentre study
-
23511561 3629423
-
van Grieken NC, Aoyama T, Chambers PA, Bottomley D, Ward LC, Inam I, Buffart TE, Das K, Lim T, Pang B. KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: results from a large international multicentre study. Br J Cancer. 2013;108(7):1495-501.
-
(2013)
Br J Cancer
, vol.108
, Issue.7
, pp. 1495-1501
-
-
Van Grieken, N.C.1
Aoyama, T.2
Chambers, P.A.3
Bottomley, D.4
Ward, L.C.5
Inam, I.6
Buffart, T.E.7
Das, K.8
Lim, T.9
Pang, B.10
-
18
-
-
0034006762
-
Distinct clinicopathologic and genetic profiles in sporadic gastric cancer with different mutator phenotypes
-
1:CAS:528:DC%2BD3cXhvVemtrc%3D 10719371
-
Wu MS, Lee CW, Shun CT, Wang HP, Lee WJ, Chang MC, Sheu JC, Lin JT. Distinct clinicopathologic and genetic profiles in sporadic gastric cancer with different mutator phenotypes. Genes Chromosomes Cancer. 2000;27(4):403-11.
-
(2000)
Genes Chromosomes Cancer
, vol.27
, Issue.4
, pp. 403-411
-
-
Wu, M.S.1
Lee, C.W.2
Shun, C.T.3
Wang, H.P.4
Lee, W.J.5
Chang, M.C.6
Sheu, J.C.7
Lin, J.T.8
-
19
-
-
0034465991
-
Microsatellite instability as a tool for the classification of gastric cancer
-
1:CAS:528:DC%2BD3MXhslyqu70%3D 11286759
-
Simpson AJ, Caballero OL, Pena SD. Microsatellite instability as a tool for the classification of gastric cancer. Trends Mol Med. 2001;7(2):76-80.
-
(2001)
Trends Mol Med
, vol.7
, Issue.2
, pp. 76-80
-
-
Simpson, A.J.1
Caballero, O.L.2
Pena, S.D.3
-
20
-
-
84918828514
-
Genetic basis for clinical response to CTLA-4 blockade in melanoma
-
25409260 4315319
-
Snyder A, Makarov V, Merghoub T, Yuan J, Zaretsky JM, Desrichard A, Walsh LA, Postow MA, Wong P, Ho TS. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N Engl J Med. 2014;371(23):2189-99.
-
(2014)
N Engl J Med
, vol.371
, Issue.23
, pp. 2189-2199
-
-
Snyder, A.1
Makarov, V.2
Merghoub, T.3
Yuan, J.4
Zaretsky, J.M.5
Desrichard, A.6
Walsh, L.A.7
Postow, M.A.8
Wong, P.9
Ho, T.S.10
-
21
-
-
84928761118
-
Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
-
1:CAS:528:DC%2BC2MXls1Wmtbg%3D
-
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, Lee W, Yuan J, Wong P, Ho TS. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science (New York, NY). 2015;348(6230):124-8.
-
(2015)
Science (New York, NY)
, vol.348
, Issue.6230
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
Kvistborg, P.4
Makarov, V.5
Havel, J.J.6
Lee, W.7
Yuan, J.8
Wong, P.9
Ho, T.S.10
-
22
-
-
84873096362
-
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
-
1:CAS:528:DC%2BC38XhvVOqsrvI 23263490 3785128
-
Palles C, Cazier JB, Howarth KM, Domingo E, Jones AM, Broderick P, Kemp Z, Spain SL, Guarino E, Salguero I. Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nat Genet. 2013;45(2):136-44.
-
(2013)
Nat Genet
, vol.45
, Issue.2
, pp. 136-144
-
-
Palles, C.1
Cazier, J.B.2
Howarth, K.M.3
Domingo, E.4
Jones, A.M.5
Broderick, P.6
Kemp, Z.7
Spain, S.L.8
Guarino, E.9
Salguero, I.10
-
23
-
-
84942285381
-
Association of polymerase e-mutated and microsatellite-instable endometrial cancers with neoantigen load, number of tumor-infiltrating lymphocytes, and expression of PD-1 and PD-L1
-
26181000
-
Howitt BE, Shukla SA, Sholl LM, Ritterhouse LL, Watkins JC, Rodig S, Stover E, Strickland KC, D'Andrea AD, Wu CJ. Association of polymerase e-mutated and microsatellite-instable endometrial cancers with neoantigen load, number of tumor-infiltrating lymphocytes, and expression of PD-1 and PD-L1. JAMA oncology. 2015;1(9):1319-23.
-
(2015)
JAMA Oncology
, vol.1
, Issue.9
, pp. 1319-1323
-
-
Howitt, B.E.1
Shukla, S.A.2
Sholl, L.M.3
Ritterhouse, L.L.4
Watkins, J.C.5
Rodig, S.6
Stover, E.7
Strickland, K.C.8
D'Andrea, A.D.9
Wu, C.J.10
-
24
-
-
84879866976
-
PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies
-
1:CAS:528:DC%2BC3sXhtValt7nJ 23674495 4102335
-
Chen BJ, Chapuy B, Ouyang J, Sun HH, Roemer MG, Xu ML, Yu H, Fletcher CD, Freeman GJ, Shipp MA. PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies. Clinical cancer research. 2013;19(13):3462-73.
-
(2013)
Clinical Cancer Research
, vol.19
, Issue.13
, pp. 3462-3473
-
-
Chen, B.J.1
Chapuy, B.2
Ouyang, J.3
Sun, H.H.4
Roemer, M.G.5
Xu, M.L.6
Yu, H.7
Fletcher, C.D.8
Freeman, G.J.9
Shipp, M.A.10
-
25
-
-
84858206832
-
Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: Implications for targeted therapy
-
1:CAS:528:DC%2BC38XktVynu70%3D 22271878 3321508
-
Green MR, Rodig S, Juszczynski P, Ouyang J, Sinha P, O'Donnell E, Neuberg D, Shipp MA. Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy. Clinical cancer research. 2012;18(6):1611-8.
-
(2012)
Clinical Cancer Research
, vol.18
, Issue.6
, pp. 1611-1618
-
-
Green, M.R.1
Rodig, S.2
Juszczynski, P.3
Ouyang, J.4
Sinha, P.5
O'Donnell, E.6
Neuberg, D.7
Shipp, M.A.8
|