The Contribution of Advanced Glycation End product (AGE) accumulation to the decline in motor function

European Review of Aging and Physical Activity

Volumn 13, Issue 1, 2016, Pages

  Drenth, Hans ^a,b   Zuidema, Sytse ^c   Bunt, Steven ^a   Bautmans, Ivan ^d   van der Schans, Cees ^a   Hobbelen, Hans ^a  

^a HANZE UNIVERSITY OF APPLIED SCIENCES   (Netherlands)

^b Zuid Oost Zorg   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

Advanced Glycation End products; Ageing; Biomarker; Motor function; Systematic review

Indexed keywords

EID: 84962409362     PISSN: 18137253     EISSN: None     Source Type: Journal    
DOI: 10.1186/s11556-016-0163-1     Document Type: Review

References (57)

1. Arvanitakis Z, Wilson RS, Schneider JA, Bienias JL, Evans DA, Bennett DA. Diabetes mellitus and progression of rigidity and gait disturbance in older persons. Neurology. 2004;63:996–1001.
2. Bellew JW, Symons TB, Vandervoort AA. Geriatric fitness: effects of aging and recommendations for exercise in older adults. Cardiopulm. Phys Ther J. 2005;16:20–31.
3. Buchman AS, Bennett DA. Loss of motor function in preclinical Alzheimer’s disease. Expert Rev Neurother. 2011;11:665–76.
4. Rikkert MGO, Rigaud AS, van Hoeyweghen RJ, de Graaf J. Geriatric syndromes: medical misnomer or progress in geriatrics? Neth J Med. 2003;61:83–7.
5. Sehl ME, Yates FE. Kinetics of human aging: I. Rates of senescence between ages 30 and 70 years in healthy people. J Gerontol A Biol Sci Med Sci United States. 2001;56:B198–208.
6. Bautmans I, Van Puyvelde K, Mets T. Sarcopenia and functional decline: pathophysiology, prevention and therapy. Acta Clin Belg. 2009;64:303–16.
7. U.S. Department of Health and Human Services. Healthy People 2000 Review. 1999.
8. Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. Journals Gerontol A, Biol Sci Med Sci. 2001;56:M146–56.
9. Sternberg SA, Schwartz AW, Karunananthan S, Bergman H, Clarfield AM. The identification of frailty: a systematic literature review. J Am Geriatr Soc. 2011;59:2129–38.
10. Sprott RL. Biomarkers of aging and disease: introduction and definitions. Exp Gerontol. 2010;45:2–4.
11. Ahmed N, Thornalley PJ. Advanced glycation endproducts: what is their relevance to diabetic complications? Diabetes, Obes Metab. 2007;9:233–45.
12. Monnier VM, Mustata GT, Biemel KL, Reihl O, Lederer MO, Zhenyu D, et al. Cross-linking of the extracellular matrix by the maillard reaction in aging and diabetes: an update on “a puzzle nearing resolution.”. Ann N Y Acad Sci. 2005;1043:533–44.
13. Rahmadi A, Steiner N, Munch G. Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer’s disease. Clin Chem Lab Med. 2011;49:385–91.
14. Uribarri J, Cai W, Peppa M, Goodman S, Ferrucci L, Striker G, et al. Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging. Journals Gerontol A, Biol Sci Med Sci. 2007;62:427–33.
15. Van Puyvelde K, Mets T, Njemini R, Beyer I, Bautmans I. Effect of advanced glycation end product intake on inflammation and aging: a systematic review. Nutr Rev. 2014;72:638–50.
16. Luevano-Contreras C, Chapman-Novakofski K. Dietary advanced glycation end products and aging. Nutrients. C. Luevano-Contreras, Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, United States; 2010;2:1247–65.
17. Peppa M, Uribarri J, Vlassara H. Aging and glycoxidant stress. Hormones (Athens). 2008;7:123–32.
18. Gasser A, Forbes JM. Advanced glycation: implications in tissue damage and disease. Protein Pept Lett. 2008;15:385–91.
19. Munch G, Westcott B, Menini T, Gugliucci A. Advanced glycation endproducts and their pathogenic roles in neurological disorders. Amino Acids. 2012;42:1221–36.
20. Hobbelen JS, Tan FE, Verhey FR, Koopmans RT, de Bie RA. Prevalence, incidence and risk factors of paratonia in patients with dementia: a one-year follow-up study. Int Psychogeriatr. 2011;23:1051–60.
21. Magelhaes PMJ, Appell H, Duarte JA. Involvement of advanced glycation end products in the pathogenesis of diabetic complications: the protective role of regular physical activity. Eur Rev Aging Phys Act. 2008;17.
22. Kjaer M. Role of extracellular matrix in adaptation of tendon and skeletal muscle to mechanical loading. Physiol Rev. 2004;84:649–98.
23. Avery NC, Bailey AJ. Enzymic and non-enzymic cross-linking mechanisms in relation to turnover of collagen: relevance to aging and exercise. Scand J Med Sci Sports. 2005;15:231–40.
24. Takahashi M. Pentosidine, an advanced glycation endproduct, and arthritis. Curr Rheumatol Rev. 2006;2:319–24.
25. Verzijl N, DeGroot J, Ben ZC, Brau-Benjamin O, Maroudas A, Bank RA, et al. Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis. Arthritis Rheum. 2002;46:114–23.
26. Verzijl N, Bank RA, TeKoppele JM, DeGroot J. AGEing and osteoarthritis: a different perspective. Curr Opin Rheumatol. 2003;15:616–22.
27. Karim L, Tang SY, Sroga GE, Vashishth D. Differences in non-enzymatic glycation and collagen cross-links between human cortical and cancellous bone. Osteoporos Int. 2013;24:2441–7.
28. Saito M, Saito M, Marumo KMSKM. Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus. Osteoporos. Int M. 2010;21:195–214. Saito, Department of Orthopaedic Surgery, Jikei University School of Medicine, Minato-ku, Tokyo 105–8461, Japan.
29. Sroga GE, Vashishth D. Effects of bone matrix proteins on fracture and fragility in osteoporosis. Curr. Osteoporos. Rep. 2012;10:141–50.
30. Schwartz A V, A.V. S. Diabetes Mellitus: Does it Affect Bone? Calcif. Tissue Int. A.V. Schwartz, Dept. of Epidemiol. and Biostatist., Univ. of California San Francisco, San Francisco, CA, United States, United States; 2003;73:515–9.
31. Lindsey JB, Cipollone F, Abdullah SM, McGuire DK. Receptor for advanced glycation end-products (RAGE) and soluble RAGE (sRAGE): cardiovascular implications. Diab Vasc Dis Res. 2009;6:7–14.
32. Schmidt AM, Yan SD, Yan SF, Stern DM. The biology of the receptor for advanced glycation end products and its ligands. Biochim Biophys Acta. 2000;1498:99–111.
33. Abate M, Schiavone C, Salini V, Andia I. Management of limited joint mobility in diabetic patients. Diabetes, Metab Syndr Obes Targets Ther. 2013;6:197–207.
34. Atienzar P, Abizanda P, Guppy A, Sinclair AJ. Diabetes and frailty: An emerging issue. Part 1: Sarcopaenia and factors affecting lower limb function. Br J Diabetes Vasc Dis. 2012;12:110–6.
35. Lebiedz-Odrobina D, Kay J. Rheumatic manifestations of diabetes mellitus. Rheum Dis Clin North Am. 2010;36:681–99.
36. Milaneschi Y, Tanaka T, Milaneschi Y, Tanaka T, Ferrucci LYMTTLF. Nutritional determinants of mobility. Curr Opin Clin Nutr Metab Care. 2010;13:625–9. L. Ferrucci, Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, Baltimore, MD 21225, United States.
37. Semba RD, Nicklett EJ, Ferrucci L. Does accumulation of advanced glycation end products contribute to the aging phenotype? J Gerontol A, Biol Sci Med Sci. 2010;65:963–75.
38. Toth C, Martinez J, Zochodne DW. RAGE, diabetes, and the nervous system. Curr Mol Med. 2007;7:766–76. C. Toth, University of Calgary, Department of Clinical Neurosciences, Calgary, AB T2N 4N1, Canada.
39. Wrobel JS, Najafi B. Diabetic foot biomechanics and gait dysfunction. J Diabetes Sci Technol. 2010;4:833–45.
40. EBRO. Dutch Cochrane Center. EBRO Assessment tool of Cohort Studies. available at http://dcc.cochrane.org/beoordelingsformulieren-en-andere-downloads.
41. Rosnow RL, Rosenthal R. Computing contrasts, effect sizes, and counternulls on other people’s published data: General procedures for research consumers. Pyschological Methods, 1996;1:331–40.
42. Cohen J. Statistical Power Analysis for the Behavioural Sciences. 2nd ed. Hillsdale: Erlbaum; 1988.
43. Dalal M, Ferrucci L, Sun K, Beck J, Fried LP, Semba RD, et al. Elevated serum advanced glycation end products and poor grip strength in older community-dwelling women. Journals Gerontol - Ser A Biol Sci Med Sci. 2009;64:132–7. R. D. Semba, Baltimore, MD 21205, United States.
44. Momma H, Niu K, Kobayashi Y, Guan L, Sato M, Guo H, et al. Skin advanced glycation end product accumulation and muscle strength among adult men. Eur J Appl Physiol. 2011;111:1545–52.
45. Semba RD, Bandinelli S, Sun K, Guralnik JM, Ferrucci L. Relationship of an advanced glycation end product, plasma carboxymethyl-lysine, with slow walking speed in older adults: the InCHIANTI study. Eur J Appl Physiol. 2010;108:191–5.
46. Sun K, Semba RD, Fried LP, Schaumberg DA, Ferrucci L, Varadhan R. Elevated serum carboxymethyl-lysine, an advanced glycation end product, predicts severe walking disability in older women: the women’s health and aging study I. J Aging Res. 2012;2012:586385.
47. Whitson HE, Arnold AM, Yee LM, Mukamal KJ, Kizer JR, Djousse L, et al. Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study. Journals Gerontol A, Biol Sci Med Sci. 2014;69:710–6.
48. Tanaka K, Kanazawa I, Sugimoto T. Elevated Serum Pentosidine and Decreased Serum IGF-I Levels are Associated with Loss of Muscle Mass in Postmenopausal Women with Type 2 Diabetes Mellitus. Exp. Clin. Endocrinol. Diabetes. I. Kanazawa. Japan: Department of Internal Medicine 1, Shimane University Faculty of Medicine, Izumo; 2015. p. 693–8501.
49. La Maza MPD, Uribarri J, Olivares D, Hirsch S, Leiva L, Barrera G, et al. Weight increase is associated with skeletal muscle immunostaining for advanced glycation end products, receptor for advanced glycation end products, and oxidation injury. Rejuvenation Res. 2008;11:1041–8.
50. Shah KM, Clark BR, McGill JB, Lang CE, Maynard J, Mueller MJ. Relationship between skin intrinsic fluorescence--an indicator of advanced glycation end products--and upper extremity impairments in individuals with diabetes mellitus. Phys Ther. 2015;95:1111–9 9. Department of Physical Therapy, Arcadia University, Clenside, Pennsylvania: American Physical Therapy Association.
51. Haus JM, Carrithers JA, Trappe SW, Haus JM, Carrithers JA, Trappe SW, et al. Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle. J Appl Physiol. 2007;103:2068–76. T.A. Trappe, Human Performance Laboratory, Ball State Univ., Muncie, IN 47306, United States.
52. Prehogan A, Cohen CI. Motor dysfunction in dementias. Geriatrics. 2004;59(53–4):56,59–60.
53. Meerwaldt R, Graaff R, Oomen PH, Links TP, Jager JJ, Alderson NL, et al. Simple non-invasive assessment of advanced glycation endproduct accumulation. Diabetologia. 2004;47:1324–30.
54. Kilhovd BK, Juutilainen A, Lehto S, Ronnemaa T, Torjesen PA, Birkeland KI, et al. High serum levels of advanced glycation end products predict increased coronary heart disease mortality in nondiabetic women but not in nondiabetic men: a population-based 18-year follow-up study. Arterioscler Thromb Vasc Biol. 2005;25:815–20.
55. Kilhovd BK, Juutilainen A, Lehto S, Ronnemaa T, Torjesen PA, Hanssen KF, et al. Increased serum levels of advanced glycation endproducts predict total, cardiovascular and coronary mortality in women with type 2 diabetes: a population-based 18 year follow-up study. Diabetologia. 2007;50:1409–17.
56. Prasad C, Imrhan V, Marotta F, Juma S, Vijayagopal P. Lifestyle and Advanced Glycation End Products (AGEs) burden: its relevance to healthy aging. Aging Dis. 2014;5:212–7.
57. Couppé C, Svensson R, Grosset J, Kovanen V, Nielsen R, Olsen M, et al. Life-long endurance running is associated with reduced glycation and mechanical stress in connective tissue. Age (Omaha). C. Couppé, Department of Physical Therapy, Musculoskeletal Rehabilitation Research Unit, Bispebjerg Hospital, Copenhagen, Denmark, Netherlands; 2014;36:9665.