Concentration-induced j-aggregate formation causes a biphasic change in the release of trans-combretastatin A4 disodium phosphate from archaeosomes and the subsequent cytotoxicity on mammary cancer cells

Molecular Pharmaceutics

Volumn 12, Issue 10, 2015, Pages 3724-3734

  Daswani, Varsha P ^a   Ayesa, Umme ^a   Venegas, Berenice ^a   Chong, Parkson Lee Gau ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Archaeal tetraether liposomes; Cis to trans isomerization; Cytotoxicity; Fluorescence; J aggregates; Mechanism of drug release; Self quenching; Vascular disrupting agent

Indexed keywords

COMBRETASTATIN A4 PHOSPHATE; LIPOSOME; ANTINEOPLASTIC AGENT; FLUORESCENT DYE; STILBENE DERIVATIVE;

AQUEOUS SOLUTION; ARTICLE; BREAST CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG RELEASE; EXCITATION; HUMAN; HUMAN CELL; ISOMERIZATION; LIPOSOMAL DELIVERY; MCF 7 CELL LINE; NONHUMAN; PRIORITY JOURNAL; RATE CONSTANT; SULFOLOBUS; SULFOLOBUS ACIDOCALDARIOUS; BREAST NEOPLASMS; DRUG DELIVERY SYSTEM; DRUG EFFECTS; FEMALE; METABOLISM; PROCEDURES;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; DRUG DELIVERY SYSTEMS; FEMALE; FLUORESCENT DYES; HUMANS; LIPOSOMES; MCF-7 CELLS; STILBENES;

EID: 84962384313     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00500     Document Type: Article

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