-
1
-
-
0842311621
-
Vascular targeting agents as cancer therapeutics
-
doi:10.1158/1078-0432.CCR-0642-03
-
P. E. Thorpe 2004 Vascular targeting agents as cancer therapeutics Clin. Cancer Res. 10 415 427 doi:10.1158/1078-0432.CCR-0642-03
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 415-427
-
-
Thorpe, P.E.1
-
2
-
-
0035131992
-
Comparative effects of combretastatin A-4 disodium phosphate and 5,6-dimethylxanthenone-4-acetic acid on blood perfusion in a murine tumour and normal tissues
-
doi:10.1080/09553000010007695
-
R. Murata J. Overgaard M. R. Horsman 2001 Comparative effects of combretastatin A-4 disodium phosphate and 5,6-dimethylxanthenone-4-acetic acid on blood perfusion in a murine tumour and normal tissues Int. J. Radiat. Biol. 77 195 204 doi:10.1080/09553000010007695
-
(2001)
Int. J. Radiat. Biol.
, vol.77
, pp. 195-204
-
-
Murata, R.1
Overgaard, J.2
Horsman, M.R.3
-
3
-
-
0032950870
-
Anti-vascular approaches to solid tumour therapy: Evaluation of combretastatin A4 phosphate
-
D. J. Chaplin G. R. Pettit S. A. Hill 1999 Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate Anticancer Res. 19 189 195
-
(1999)
Anticancer Res.
, vol.19
, pp. 189-195
-
-
Chaplin, D.J.1
Pettit, G.R.2
Hill, S.A.3
-
4
-
-
0032758736
-
In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
-
doi:10.1038/sj.bjc.6692174
-
K. Grosios S. E. Holwell A. T. McGown G. R. Pettit M. C. Bibby 1999 In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug Br. J. Cancer 81 1318 1327 doi:10.1038/sj.bjc.6692174
-
(1999)
Br. J. Cancer
, vol.81
, pp. 1318-1327
-
-
Grosios, K.1
Holwell, S.E.2
Pettit, G.R.3
Bibby, M.C.4
-
5
-
-
0037681850
-
Pharmacokinetics of pegylated liposomal Doxorubicin: Review of animal and human studies
-
doi:10.2165/00003088-200342050-00002
-
A. Gabizon H. Shmeeda Y. Barenholz 2003 Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies Clin. Pharmacokinet. 42 419 436 doi:10.2165/00003088-200342050-00002
-
(2003)
Clin. Pharmacokinet.
, vol.42
, pp. 419-436
-
-
Gabizon, A.1
Shmeeda, H.2
Barenholz, Y.3
-
6
-
-
0141990623
-
Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin
-
doi:10.1016/S0168-3659(03)00240-2
-
R. M. Schiffelers G. A. Koning T. L. ten Hagen M. H. Fens A. J. Schraa A. P. Janssen R. J. Kok G. Molema G. Storm 2003 Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin J. Control. Release 91 115 122 doi:10.1016/S0168-3659(03)00240-2
-
(2003)
J. Control. Release
, vol.91
, pp. 115-122
-
-
Schiffelers, R.M.1
Koning, G.A.2
Ten Hagen, T.L.3
Fens, M.H.4
Schraa, A.J.5
Janssen, A.P.6
Kok, R.J.7
Molema, G.8
Storm, G.9
-
7
-
-
0035254653
-
In vivo antitumor effect of vascular targeting combined with either ionizing radiation or anti-angiogenesis treatment
-
doi:10.1016/S0360-3016(00)01470-X
-
W. Landuyt B. Ahmed S. Nuyts J. Theys M. O. P. de Beeck A. Rijnders J. Anne A. van Oosterom B. W. van den P. Lambin 2001 In vivo antitumor effect of vascular targeting combined with either ionizing radiation or anti-angiogenesis treatment Int. J. Radiat. Oncol. Biol. Phys. 49 443 450 doi:10.1016/S0360- 3016(00)01470-X
-
(2001)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.49
, pp. 443-450
-
-
Landuyt, W.1
Ahmed, B.2
Nuyts, S.3
Theys, J.4
De Beeck, M.O.P.5
Rijnders, A.6
Anne, J.7
Van Oosterom, A.8
Van Den, B.W.9
Lambin, P.10
-
8
-
-
0031775298
-
Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
-
doi:10.1016/S0360-3016(98)00358-7
-
W. R. Wilson A. E. Li D. S. M. Cowan B. G. Siim 1998 Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid Int. J. Radiat. Oncol. Biol. Phys. 42 905 908 doi:10.1016/S0360-3016(98) 00358-7
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.42
, pp. 905-908
-
-
Wilson, W.R.1
Li, A.E.2
Cowan, D.S.M.3
Siim, B.G.4
-
9
-
-
0036744708
-
Targeting microparticles to select tissue via radiation-induced upregulation of endothelial cell adhesion molecules
-
doi:10.1023/A:1020350708672
-
M. F. Kiani H. Yuan X. Chen L. Smith M. W. Gaber D. J. Goetz 2002 Targeting microparticles to select tissue via radiation-induced upregulation of endothelial cell adhesion molecules Pharm. Res. 19 1317 1322 doi:10.1023/A:1020350708672
-
(2002)
Pharm. Res.
, vol.19
, pp. 1317-1322
-
-
Kiani, M.F.1
Yuan, H.2
Chen, X.3
Smith, L.4
Gaber, M.W.5
Goetz, D.J.6
-
10
-
-
23744495032
-
Targeting of the antivascular drug combretastatin to irradiated tumors results in tumor growth delay
-
doi:10.1007/s11095-005-5646-0
-
C. B. Pattillo F. Sari-Sarraf R. Nallamothu B. M. Moore G. C. Wood M. F. Kiani 2005 Targeting of the antivascular drug combretastatin to irradiated tumors results in tumor growth delay Pharm. Res. 22 1117 1120 doi:10.1007/s11095-005-5646-0
-
(2005)
Pharm. Res.
, vol.22
, pp. 1117-1120
-
-
Pattillo, C.B.1
Sari-Sarraf, F.2
Nallamothu, R.3
Moore, B.M.4
Wood, G.C.5
Kiani, M.F.6
-
11
-
-
1842639009
-
Radiation-guided drug delivery systems
-
doi:10.1586/14737140.4.2.283
-
D. R. Stacy B. Lu D. E. Hallahan 2004 Radiation-guided drug delivery systems Expert Rev. Anticancer Ther. 4 283 288 doi:10.1586/14737140.4.2.283
-
(2004)
Expert Rev. Anticancer Ther.
, vol.4
, pp. 283-288
-
-
Stacy, D.R.1
Lu, B.2
Hallahan, D.E.3
-
12
-
-
19444363158
-
Radiation-induced up-regulation of adhesion molecules in brain microvasculature and their modulation by dexamethasone
-
doi:10.1667/RR3361
-
H. Yuan D. J. Goetz M. W. Gaber A. C. Issekutz T. E. Merchant M. F. Kiani 2005 Radiation-induced up-regulation of adhesion molecules in brain microvasculature and their modulation by dexamethasone Radiat. Res. 163 544 551 doi:10.1667/RR3361
-
(2005)
Radiat. Res.
, vol.163
, pp. 544-551
-
-
Yuan, H.1
Goetz, D.J.2
Gaber, M.W.3
Issekutz, A.C.4
Merchant, T.E.5
Kiani, M.F.6
-
13
-
-
0029066847
-
Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a)
-
doi:10.1021/jm00010a011
-
G. R. Pettit S. B. Singh M. R. Boyd E. Hamel R. K. Pettit J. M. Schmidt F. Hogan 1995 Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a) J. Med. Chem. 38 1666 1672 doi:10.1021/jm00010a011
-
(1995)
J. Med. Chem.
, vol.38
, pp. 1666-1672
-
-
Pettit, G.R.1
Singh, S.B.2
Boyd, M.R.3
Hamel, E.4
Pettit, R.K.5
Schmidt, J.M.6
Hogan, F.7
-
14
-
-
1942455271
-
Molecular dynamics simulations of hydrophilic pores in lipid bilayers
-
H. Leontiadou A. E. Mark S. J. Marrink 2004 Molecular dynamics simulations of hydrophilic pores in lipid bilayers Biophys. J. 86 2156 2164
-
(2004)
Biophys. J.
, vol.86
, pp. 2156-2164
-
-
Leontiadou, H.1
Mark, A.E.2
Marrink, S.J.3
-
15
-
-
70449246528
-
Phosphorus assay in column chromatography
-
G. R. Bartlett 1959 Phosphorus assay in column chromatography J. Biol. Chem. 234 466 468
-
(1959)
J. Biol. Chem.
, vol.234
, pp. 466-468
-
-
Bartlett, G.R.1
-
17
-
-
0032961720
-
Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements
-
doi:10.1038/sj.bjc.6690072
-
B. M. Fenton S. F. Paoni J. Lee C. J. Koch E. M. Lord 1999 Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements Br. J. Cancer 79 464 471 doi:10.1038/sj.bjc.6690072
-
(1999)
Br. J. Cancer
, vol.79
, pp. 464-471
-
-
Fenton, B.M.1
Paoni, S.F.2
Lee, J.3
Koch, C.J.4
Lord, E.M.5
-
18
-
-
4544277194
-
Combretastatin A4 phosphate: Background and current clinical status
-
doi:10.1517/13543784.13.9.1171
-
S. L. Young D. J. Chaplin 2004 Combretastatin A4 phosphate: background and current clinical status Expert Opin. Investig. Drugs 13 1171 1182 doi:10.1517/13543784.13.9.1171
-
(2004)
Expert Opin. Investig. Drugs
, vol.13
, pp. 1171-1182
-
-
Young, S.L.1
Chaplin, D.J.2
-
19
-
-
20044395276
-
Phase i trial of combretastatin a-4 phosphate with carboplatin
-
doi:10.1158/1078-0432.CCR-04-1434
-
J. H. Bilenker K. T. Flaherty M. Rosen L. Davis M. Gallagher J. P. Stevenson W. Sun D. Vaughn B. Giantonio R. Zimmer M. Schnall P. J. O'Dwyer 2005 Phase I trial of combretastatin a-4 phosphate with carboplatin Clin. Cancer Res. 11 1527 1533 doi:10.1158/1078-0432.CCR-04-1434
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 1527-1533
-
-
Bilenker, J.H.1
Flaherty, K.T.2
Rosen, M.3
Davis, L.4
Gallagher, M.5
Stevenson, J.P.6
Sun, W.7
Vaughn, D.8
Giantonio, B.9
Zimmer, R.10
Schnall, M.11
O'Dwyer, P.J.12
-
20
-
-
0642307227
-
Phase i trial of the antivascular agent combretastatin A4 phosphate on a 5-day schedule to patients with cancer: Magnetic resonance imaging evidence for altered tumor blood flow
-
doi:10.1200/JCO.2003.12.986
-
J. P. Stevenson M. Rosen W. Sun M. Gallagher D. G. Haller D. Vaughn B. Giantonio R. Zimmer W. P. Petros M. Stratford D. Chaplin S. L. Young M. Schnall P. J. O'Dwyer 2003 Phase I trial of the antivascular agent combretastatin A4 phosphate on a 5-day schedule to patients with cancer: magnetic resonance imaging evidence for altered tumor blood flow J. Clin. Oncol. 21 4428 4438 doi:10.1200/JCO.2003.12.986
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 4428-4438
-
-
Stevenson, J.P.1
Rosen, M.2
Sun, W.3
Gallagher, M.4
Haller, D.G.5
Vaughn, D.6
Giantonio, B.7
Zimmer, R.8
Petros, W.P.9
Stratford, M.10
Chaplin, D.11
Young, S.L.12
Schnall, M.13
O'Dwyer, P.J.14
-
21
-
-
0042386700
-
Phase i clinical trial of weekly combretastatin A4 phosphate: Clinical and pharmacokinetic results
-
doi:10.1200/JCO.2003.05.185
-
G. J. Rustin S. M. Galbraith H. Anderson M. Stratford L. K. Folkes L. Sena L. Gumbrell P. M. Price 2003 Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results J. Clin. Oncol. 21 2815 2822 doi:10.1200/JCO.2003.05.185
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2815-2822
-
-
Rustin, G.J.1
Galbraith, S.M.2
Anderson, H.3
Stratford, M.4
Folkes, L.K.5
Sena, L.6
Gumbrell, L.7
Price, P.M.8
-
22
-
-
0037096814
-
A phase i pharmacokinetic and translational study of the novel vascular targeting agent combretastatin a-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer
-
A. Dowlati K. Robertson M. Cooney W. P. Petros M. Stratford J. Jesberger N. Rafie B. Overmoyer V. Makkar B. Stambler A. Taylor J. Waas J. S. Lewin K. R. McCrae S. C. Remick 2002 A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin a-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer Cancer Res. 62 3408 3416
-
(2002)
Cancer Res.
, vol.62
, pp. 3408-3416
-
-
Dowlati, A.1
Robertson, K.2
Cooney, M.3
Petros, W.P.4
Stratford, M.5
Jesberger, J.6
Rafie, N.7
Overmoyer, B.8
Makkar, V.9
Stambler, B.10
Taylor, A.11
Waas, J.12
Lewin, J.S.13
Remick, S.C.14
-
23
-
-
33645791307
-
A tumor vasculature targeted liposome delivery system for combretastatin A4: Design, characterization, and in vitro evaluation
-
doi:10.1208/pt070232
-
R. Nallamothu G. C. Wood C. B. Pattillo R. C. Scott M. F. Kiani B. M. Moore L. A. Thoma 2006 A tumor vasculature targeted liposome delivery system for combretastatin A4: design, characterization, and in vitro evaluation AAPS PharmSciTech. 7 E32 doi:10.1208/pt070232
-
(2006)
AAPS PharmSciTech.
, vol.7
, pp. 32
-
-
Nallamothu, R.1
Wood, G.C.2
Pattillo, C.B.3
Scott, R.C.4
Kiani, M.F.5
Moore, B.M.6
Thoma, L.A.7
-
24
-
-
39749172398
-
Tumor hypoxia in cancer therapy
-
J. M. Brown 2007 Tumor hypoxia in cancer therapy Methods Enzymol. 435 297 321
-
(2007)
Methods Enzymol.
, vol.435
, pp. 297-321
-
-
Brown, J.M.1
-
25
-
-
33745671324
-
A targeted liposome delivery system for combretastatin A4: Formulation optimization through drug loading and in vitro release studies
-
R. Nallamothu G. C. Wood M. F. Kiani B. M. Moore F. P. Horton L. A. Thoma 2006 A targeted liposome delivery system for combretastatin A4: formulation optimization through drug loading and in vitro release studies PDA J. Pharm. Sci. Technol. 60 144 155
-
(2006)
PDA J. Pharm. Sci. Technol.
, vol.60
, pp. 144-155
-
-
Nallamothu, R.1
Wood, G.C.2
Kiani, M.F.3
Moore, B.M.4
Horton, F.P.5
Thoma, L.A.6
|