TLR4-dependent secretion by hepatic stellate cells of the neutrophil-chemoattractant CXCL1 mediates liver response to gut microbiota

PLoS ONE

Volumn 11, Issue 3, 2016, Pages

  Bigorgne, Amélie E ^a   John, Beena ^a,c   Ebrahimkhani, Mohammad R ^a,d   Shimizu Albergine, Masami ^b,e   Campbell, Jean S ^b   Crispe, Ian N ^a,b,e  

^a SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d Massachusetts Institute of Technology   (United States)

^e UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; TOLL LIKE RECEPTOR 4; CXCL1 PROTEIN, MOUSE; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ASSAY; CELL HOMING; CELL POPULATION; CELL SELECTION; CONTROLLED STUDY; CYTOKINE RELEASE; GENE EXPRESSION; IN VITRO STUDY; INTESTINE FLORA; INTRACELLULAR SIGNALING; MICROARRAY ANALYSIS; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STEADY STATE; STELLATE CELL; ANIMAL; C57BL MOUSE; HEPATIC STELLATE CELL; IMMUNOLOGY; LIVER; NEUTROPHIL; SIGNAL TRANSDUCTION;

ANIMALS; CHEMOKINE CXCL1; GASTROINTESTINAL MICROBIOME; HEPATIC STELLATE CELLS; INTERLEUKIN-8; LIPOPOLYSACCHARIDES; LIVER; MICE; MICE, INBRED C57BL; NEUTROPHILS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84962374022     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0151063     Document Type: Article

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