Neutrophil priming by hypoxic preconditioning protects against epithelial barrier damage and enteric bacterial translocation in intestinal ischemia/reperfusion

Laboratory Investigation

Volumn 92, Issue 5, 2012, Pages 783-796

  Lu, Yen Zhen ^a   Wu, Chi Chin ^a   Huang, Yi Chen ^a   Huang, Ching Ying ^a   Yang, Chung Yi ^b   Lee, Tsung Chun ^b   Chen, Chau Fong ^a   Yu, Linda Chia Hui ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Bacterial translocation; Epithelial permeability; Hypoxic preconditioning; Intestinal barrier function; Mesenteric ischemia; Neutrophil priming; Respiratory burst activity

Indexed keywords

CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 3; HYDROGEN PEROXIDE; MYELOPEROXIDASE; PROTEIN P47; PROTEIN P67; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BACTERIAL TRANSLOCATION; BACTERIUM CULTURE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENTEROBACTERIACEAE; ENZYME ACTIVITY; EX VIVO STUDY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HYPOBARISM; HYPOXIA; IN VIVO STUDY; INTESTINE ISCHEMIA; INTESTINE MUCOSA PERMEABILITY; ISCHEMIC PRECONDITIONING; LIVER; MALE; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SPLEEN; WISTAR RAT;

ANIMALS; ANOXIA; BACTERIAL TRANSLOCATION; CELL MEMBRANE; CELLS, CULTURED; CHEMOKINE CXCL1; CHEMOKINE CXCL2; INTESTINAL MUCOSA; INTESTINES; LIVER; MALE; NEUTROPHILS; PERMEABILITY; PEROXIDASE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SPLEEN;

EID: 84860293950     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2012.11     Document Type: Article

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