A polygenic burden of rare variants across extracellular matrix genes among individuals with adolescent idiopathic scoliosis

Human Molecular Genetics

Volumn 25, Issue 1, 2016, Pages 202-209

  Haller, Gabe ^a   Alvarado, David ^a   Mccall, Kevin ^a   Yang, Ping ^a   Cruchaga, Carlos ^b   Harms, Matthew ^a   Goate, Alison ^b   Willing, Marcia ^b   Morcuende, Jose A ^c   Baschal, Erin ^d   Miller, Nancy H ^d   Wise, Carol ^e,f,g   Dobbs, Matthew B ^a,h   Gurnett, Christina A ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e TEXAS SCOTTISH RITE HOSPITAL FOR CHILDREN   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^h SHRINERS HOSPITAL FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN;

ADOLESCENT IDIOPATHIC SCOLIOSIS; ARACHNODACTYLY; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; EUROPEAN; EXOME; EXTRACELLULAR MATRIX; FEMALE; GENE REPLICATION; GENE SEQUENCE; GENE TARGETING; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; JOINT LAXITY; MAJOR CLINICAL STUDY; MALE; MARFAN SYNDROME; MISSENSE MUTATION; PRIORITY JOURNAL; COHORT ANALYSIS; GENETIC VARIATION; GENETICS; KYPHOSIS; MULTIFACTORIAL INHERITANCE; SCOLIOSIS; YOUNG ADULT;

COHORT STUDIES; COLLAGEN; EXOME; EXTRACELLULAR MATRIX; FEMALE; GENETIC VARIATION; HUMANS; KYPHOSIS; MALE; MULTIFACTORIAL INHERITANCE; SCOLIOSIS; YOUNG ADULT;

EID: 84962175728     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv463     Document Type: Article

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