Activation of FoxM1 revitalizes the replicative potential of aged β-cells in male mice and enhances insulin secretion

Diabetes

Volumn 64, Issue 11, 2015, Pages 3829-3838

  Golson, Maria L ^a,b   Dunn, Jennifer C ^a,b   Maulis, Matthew F ^a,b   Dadi, Prasanna K ^c   Osipovich, Anna B ^c,d   Magnuson, Mark A ^c,d   Jacobson, David A ^c   Gannon, Maureen ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA B KINASE; CALCIUM ION; FOXM1 PROTEIN; GLUCOSE; HISTONE H2AX; INSULIN; PHOSPHOTRANSFERASE; PROTEIN; PROTEIN P16; S PHASE ASSOCIATED KINASE 2; UNCLASSIFIED DRUG; FORKHEAD BOX PROTEIN M1; FORKHEAD TRANSCRIPTION FACTOR; FOXM1 PROTEIN, MOUSE;

ACINAR CELL; AGE; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL DIVISION; CELL FUNCTION; CELL PROLIFERATION; CELL SELECTION; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; ENDOREDUPLICATION; EX VIVO STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; INSULIN RELEASE; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; SURVIVAL; TUNEL ASSAY; ANIMAL; GENETICS; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; SECRETION (PROCESS);

ANIMALS; CELL PROLIFERATION; DIABETES MELLITUS, TYPE 2; FORKHEAD BOX PROTEIN M1; FORKHEAD TRANSCRIPTION FACTORS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE;

EID: 84962138860     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0465     Document Type: Article

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