메뉴 건너뛰기




Volumn 11, Issue 3, 2016, Pages

Abnormal salivary total and oligomeric alpha-synuclein in Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; OLIGOMER; BIOLOGICAL MARKER; PROTEIN AGGREGATE;

EID: 84962069192     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0151156     Document Type: Article
Times cited : (105)

References (45)
  • 1
    • 84893858665 scopus 로고    scopus 로고
    • Extracellular α-synuclein-A novel and crucial factor in Lewy body diseases
    • 24468877
    • Lee HJ, Bae EJ, Lee SJ. Extracellular α-synuclein-a novel and crucial factor in Lewy body diseases. Nat Rev Neurol 2014;10:92-98. doi: 10.1038/nrneurol.2013.275 PMID: 24468877
    • (2014) Nat Rev Neurol , vol.10 , pp. 92-98
    • Lee, H.J.1    Bae, E.J.2    Lee, S.J.3
  • 3
    • 71849092190 scopus 로고    scopus 로고
    • Neuropathological assessment of Parkinson's disease: Refining the diagnostic criteria
    • 19909913
    • Dickson DW, Braak H, Duda JE, Duyckaerts C, Gasser T, Halliday GM, et al. Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria. Lancet Neurol 2009;8:1150-1157. doi: 10.1016/S1474-4422 (09) 70238-8 PMID: 19909913
    • (2009) Lancet Neurol , vol.8 , pp. 1150-1157
    • Dickson, D.W.1    Braak, H.2    Duda, J.E.3    Duyckaerts, C.4    Gasser, T.5    Halliday, G.M.6
  • 4
    • 84859577559 scopus 로고    scopus 로고
    • A-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer
    • 22315227
    • Fauvet B, Mbefo MK, Fares MB, Desobry C, Michael S, Ardah MT, Tsika E, et al. a-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer. J Biol Chem 2012;287:15345-15364. doi: 10.1074/jbc. M111.318949 PMID: 22315227
    • (2012) J Biol Chem , vol.287 , pp. 15345-15364
    • Fauvet, B.1    Mbefo, M.K.2    Fares, M.B.3    Desobry, C.4    Michael, S.5    Ardah, M.T.6    Tsika, E.7
  • 5
    • 84884250340 scopus 로고    scopus 로고
    • The function of a-synuclein
    • 24050397
    • Bendor JT, Logan TP, Edwards RH. The function of a-synuclein. Neuron 2013;79:1044-1066. doi: 10. 1016/j.neuron. 2013.09.004 PMID: 24050397
    • (2013) Neuron , vol.79 , pp. 1044-1066
    • Bendor, J.T.1    Logan, T.P.2    Edwards, R.H.3
  • 6
    • 79551540871 scopus 로고    scopus 로고
    • Different sub-cellular localization of alphasynuclein in the C57BL\6J mouse's central nervous system by two novel monoclonal antibodies
    • 21172422
    • Vivacqua G, Casini A, Vaccaro R, Fornai F, Yu S, D'Este L. Different sub-cellular localization of alphasynuclein in the C57BL\6J mouse's central nervous system by two novel monoclonal antibodies. J Chem Neuroanat 2011;41:97-110. doi: 10.1016/j.jchemneu.2010.12.003 PMID: 21172422
    • (2011) J Chem Neuroanat , vol.41 , pp. 97-110
    • Vivacqua, G.1    Casini, A.2    Vaccaro, R.3    Fornai, F.4    Yu, S.5    D'Este, L.6
  • 7
    • 0242668337 scopus 로고    scopus 로고
    • Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
    • 12702875
    • Kayed R, Head E, Thompson JL, Milton SC, Cotman CW, Glabe CG, et al. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 2003;300:486-489. PMID: 12702875
    • (2003) Science , vol.300 , pp. 486-489
    • Kayed, R.1    Head, E.2    Thompson, J.L.3    Milton, S.C.4    Cotman, C.W.5    Glabe, C.G.6
  • 8
    • 80054755695 scopus 로고    scopus 로고
    • Pathological roles of alpha-synuclein in neurological disorders
    • 22014436
    • Vekrellis K, Xilouri M, Emmanouilidou E, Rideout HJ, Stefanis L. Pathological roles of alpha-synuclein in neurological disorders. Lancet Neurol 2011;10:1015-1025. doi: 10.1016/S1474-4422 (11) 70213-7 PMID: 22014436
    • (2011) Lancet Neurol , vol.10 , pp. 1015-1025
    • Vekrellis, K.1    Xilouri, M.2    Emmanouilidou, E.3    Rideout, H.J.4    Stefanis, L.5
  • 9
    • 65249162241 scopus 로고    scopus 로고
    • Detection of elevated levels of soluble [alpha]-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies
    • 19155272
    • Paleologou KE, Kragh CL, Mann DM, Salem SA, Al-Shami R, Allsop D, et al. Detection of elevated levels of soluble [alpha]-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies. Brain 2009;132:1093-1101. doi: 10.1093/brain/awn349 PMID: 19155272
    • (2009) Brain , vol.132 , pp. 1093-1101
    • Paleologou, K.E.1    Kragh, C.L.2    Mann, D.M.3    Salem, S.A.4    Al-Shami, R.5    Allsop, D.6
  • 10
    • 0036278335 scopus 로고    scopus 로고
    • Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
    • 12042811
    • Xu J, Kao SY, Lee FJ, Song W, Jin LW, Yankner BA. Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease. Nat Med 2002;8:600-606. PMID: 12042811
    • (2002) Nat Med , vol.8 , pp. 600-606
    • Xu, J.1    Kao, S.Y.2    Lee, F.J.3    Song, W.4    Jin, L.W.5    Yankner, B.A.6
  • 11
  • 12
    • 85012093582 scopus 로고    scopus 로고
    • Seeking a Mechanism for the Toxicity of Oligomeric α-Synuclein
    • 25816357
    • Roberts HL, Brown DR. Seeking a Mechanism for the Toxicity of Oligomeric α-Synuclein. Biomolecules 2015;5:282-305. doi: 10.3390/biom5020282 PMID: 25816357
    • (2015) Biomolecules , vol.5 , pp. 282-305
    • Roberts, H.L.1    Brown, D.R.2
  • 13
    • 33748325848 scopus 로고    scopus 로고
    • Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease
    • 16930553
    • Tokuda T, Salem SA, Alisop D, Mizuno T, Nakagawa M, Qureshi MM, et al. Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease. Biochem Biophys Res Commun 2006;349:162-166. PMID: 16930553
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 162-166
    • Tokuda, T.1    Salem, S.A.2    Alisop, D.3    Mizuno, T.4    Nakagawa, M.5    Qureshi, M.M.6
  • 14
    • 79951720856 scopus 로고    scopus 로고
    • Alpha-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: A cohort study
    • 21317042
    • Mollenhauer B, Locascio JJ, Schulz-Schaeffer W, Sixel-Doring F, Trenkwalder C, Schlossmacher MG. alpha-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study. Lancet Neurol 2011;10:230-240. doi: 10.1016/S1474-4422 (11) 70014-X PMID: 21317042
    • (2011) Lancet Neurol , vol.10 , pp. 230-240
    • Mollenhauer, B.1    Locascio, J.J.2    Schulz-Schaeffer, W.3    Sixel-Doring, F.4    Trenkwalder, C.5    Schlossmacher, M.G.6
  • 15
    • 79960613150 scopus 로고    scopus 로고
    • Cerebrospinal fluid Tau/alpha-synuclein ratio in Parkinson's disease and degenerative dementias
    • 21469206
    • Parnetti L, Chiasserini D, Bellomo G, Giannandrea D, De Carlo C, Qureshi MM, et al. Cerebrospinal fluid Tau/alpha-synuclein ratio in Parkinson's disease and degenerative dementias. Mov Disord 2011;26:1428-1435. doi: 10.1002/mds.23670 PMID: 21469206
    • (2011) Mov Disord , vol.26 , pp. 1428-1435
    • Parnetti, L.1    Chiasserini, D.2    Bellomo, G.3    Giannandrea, D.4    De Carlo, C.5    Qureshi, M.M.6
  • 17
    • 41149110768 scopus 로고    scopus 로고
    • Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: Autonomic pathway implicated in Parkinson's disease?
    • 18407422
    • Phillips RJ, Walter GC, Wilder SL, Baronowsky FA, Powley TL. Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease? Neuroscience 2008;153:733-750. doi: 10.1016/j.neuroscience.2008.02.074 PMID: 18407422
    • (2008) Neuroscience , vol.153 , pp. 733-750
    • Phillips, R.J.1    Walter, G.C.2    Wilder, S.L.3    Baronowsky, F.A.4    Powley, T.L.5
  • 18
    • 84876807876 scopus 로고    scopus 로고
    • Mind the gut: Secretion of alpha-synuclein by enteric neurons
    • 23448303
    • Grathwohl SA, Steiner JA, Britschgi M, Brundin P. Mind the gut: secretion of alpha-synuclein by enteric neurons. J Neurochem 2013;125:487-490. doi: 10.1111/jnc.12191 PMID: 23448303
    • (2013) J Neurochem , vol.125 , pp. 487-490
    • Grathwohl, S.A.1    Steiner, J.A.2    Britschgi, M.3    Brundin, P.4
  • 19
    • 84923536410 scopus 로고    scopus 로고
    • Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease
    • 25589666
    • Visanji NP, Marras C, Kern DS, Al Dakheel A, Gao A, Liu LW, et al. Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease. Neurology 2015;84:609-616. PMID: 25589666
    • (2015) Neurology , vol.84 , pp. 609-616
    • Visanji, N.P.1    Marras, C.2    Kern, D.S.3    Al Dakheel, A.4    Gao, A.5    Liu, L.W.6
  • 20
    • 84902076322 scopus 로고    scopus 로고
    • Skin nerve α-synuclein deposits: A biomarker for idiopathic Parkinson disease
    • 24634456
    • Donadio V, Incensi A, Leta V, Giannoccaro MP, Scaglione C, Martinelli P, et al. Skin nerve α-synuclein deposits: a biomarker for idiopathic Parkinson disease. Neurology 2014;82:1362-1369. doi: 10.1212/WNL.0000000000000316 PMID: 24634456
    • (2014) Neurology , vol.82 , pp. 1362-1369
    • Donadio, V.1    Incensi, A.2    Leta, V.3    Giannoccaro, M.P.4    Scaglione, C.5    Martinelli, P.6
  • 21
    • 84940093905 scopus 로고    scopus 로고
    • Phosphorylated α-synuclein in skin nerve fibres differentiates Parkinson's disease from multiple system atrophy
    • 26017579
    • Zange L, Noack C, Hahn K, Stenzel W, Lipp A. Phosphorylated α-synuclein in skin nerve fibres differentiates Parkinson's disease from multiple system atrophy. Brain 2015;138:2310-2321. doi: 10.1093/brain/awv138 PMID: 26017579
    • (2015) Brain , vol.138 , pp. 2310-2321
    • Zange, L.1    Noack, C.2    Hahn, K.3    Stenzel, W.4    Lipp, A.5
  • 23
    • 77953022918 scopus 로고    scopus 로고
    • Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease
    • 20229352
    • Del Tredici K, Hawkes CH, Ghebremedhin E, Braak H. Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease. Acta Neuropathol 2010;119:703-713. doi: 10.1007/s00401-010-0665-2 PMID: 20229352
    • (2010) Acta Neuropathol , vol.119 , pp. 703-713
    • Del Tredici, K.1    Hawkes, C.H.2    Ghebremedhin, E.3    Braak, H.4
  • 24
    • 79958233724 scopus 로고    scopus 로고
    • Salivary a-synuclein and DJ-1: Potential biomarkers for Parkinson's disease
    • Devic I, Hwang H, Edgar JS, Izutsu K, Presland R, Pan C, et al. Salivary a-synuclein and DJ-1: potential biomarkers for Parkinson's disease. Brain 2010;134:1-5.
    • (2010) Brain , vol.134 , pp. 1-5
    • Devic, I.1    Hwang, H.2    Edgar, J.S.3    Izutsu, K.4    Presland, R.5    Pan, C.6
  • 25
    • 84920026565 scopus 로고    scopus 로고
    • Saliva a-synuclein and a high extinction coefficient protein: A novel approach in assessment biomarkers of Parkinson's disease
    • 25599051
    • Al-Nimer MS, Mshatat SF, Abdulla HI. Saliva a-Synuclein and A High Extinction Coefficient Protein: a novel approach in assessment biomarkers of Parkinson's disease. N Am J Med Sci 2014;6:633-637. doi: 10.4103/1947-2714.147980 PMID: 25599051
    • (2014) N Am J Med Sci , vol.6 , pp. 633-637
    • Al-Nimer, M.S.1    Mshatat, S.F.2    Abdulla, H.I.3
  • 26
    • 84862916400 scopus 로고    scopus 로고
    • Elevated levels of alpha-synuclein oligomer in the cerebrospinal fluid of drug-naive patients with Parkinson's disease
    • Park MJ, Cheon SM, Bae HR, Kim SH, Kim JW. Elevated levels of alpha-synuclein oligomer in the cerebrospinal fluid of drug-naive patients with Parkinson's disease. J Clin Neurol 2010;7:215-222.
    • (2010) J Clin Neurol , vol.7 , pp. 215-222
    • Park, M.J.1    Cheon, S.M.2    Bae, H.R.3    Kim, S.H.4    Kim, J.W.5
  • 27
    • 78649990079 scopus 로고    scopus 로고
    • Detection of elevated levels of alpha-synuclein oligomers in CSF from patients with Parkinson disease
    • 20962290
    • Tokuda T, Qureshi MM, Ardah MT, Varghese S, Shehab SA, Kasai T, et al. Detection of elevated levels of alpha-synuclein oligomers in CSF from patients with Parkinson disease. Neurology 2010;75:1766-1772. doi: 10.1212/WNL.0b013e3181fd613b PMID: 20962290
    • (2010) Neurology , vol.75 , pp. 1766-1772
    • Tokuda, T.1    Qureshi, M.M.2    Ardah, M.T.3    Varghese, S.4    Shehab, S.A.5    Kasai, T.6
  • 28
    • 0023898945 scopus 로고
    • The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
    • 2841426
    • Gibb WR, Lees AJ. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 1988;51:745-52. PMID: 2841426
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 745-752
    • Gibb, W.R.1    Lees, A.J.2
  • 29
    • 84871664204 scopus 로고    scopus 로고
    • EFNS/MDS-ES/ENS recommendations for the diagnosis of Parkinson's disease
    • 23279440
    • Berardelli A, Wenning GK, Antonini A, Berg D, Bloem BR, Bonifati V, et al. EFNS/MDS-ES/ENS recommendations for the diagnosis of Parkinson's disease. Eur J Neurol 2013;20:16-34. doi: 10.1111/ene. 12022 PMID: 23279440
    • (2013) Eur J Neurol , vol.20 , pp. 16-34
    • Berardelli, A.1    Wenning, G.K.2    Antonini, A.3    Berg, D.4    Bloem, B.R.5    Bonifati, V.6
  • 30
    • 78349261173 scopus 로고    scopus 로고
    • Systematic review of levodopa dose equivalency reporting in Parkinson's disease
    • 21069833
    • Tomlinson CL, Stowe R, Patel S, Rick C, Gray R, Clarke CE. Systematic review of levodopa dose equivalency reporting in Parkinson's disease. Mov Disord 2010;25:2649-2653. doi: 10.1002/mds. 23429 PMID: 21069833
    • (2010) Mov Disord , vol.25 , pp. 2649-2653
    • Tomlinson, C.L.1    Stowe, R.2    Patel, S.3    Rick, C.4    Gray, R.5    Clarke, C.E.6
  • 31
    • 73349120962 scopus 로고    scopus 로고
    • Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson
    • 19933974
    • Hoops S, Nazem S, Siderowf AD, Duda JE, Xie SX, Stern MB, et al. Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson. Neurology 2009;73:1738-1745. doi: 10.1212/WNL. 0b013e3181c34b47 PMID: 19933974
    • (2009) Neurology , vol.73 , pp. 1738-1745
    • Hoops, S.1    Nazem, S.2    Siderowf, A.D.3    Duda, J.E.4    Xie, S.X.5    Stern, M.B.6
  • 32
    • 84861202968 scopus 로고    scopus 로고
    • Sensitivity and specificity of Addenbrooke's Cognitive Examination, Mattis Dementia Rating Scale, Frontal Assessment Battery and Mini Mental State Examination for diagnosing dementia in Parkinson's disease
    • 22405839
    • Kaszas B, Kovacs N, Balas I, Kallai J, Aschermann Z, Kerekes Z, et al. Sensitivity and specificity of Addenbrooke's Cognitive Examination, Mattis Dementia Rating Scale, Frontal Assessment Battery and Mini Mental State Examination for diagnosing dementia in Parkinson's disease. Parkinsonism Relat Disord 2012;18:553-556. doi: 10.1016/j.parkreldis.2012.02.010 PMID: 22405839
    • (2012) Parkinsonism Relat Disord , vol.18 , pp. 553-556
    • Kaszas, B.1    Kovacs, N.2    Balas, I.3    Kallai, J.4    Aschermann, Z.5    Kerekes, Z.6
  • 33
    • 77950223687 scopus 로고    scopus 로고
    • DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
    • 20157014
    • Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, Galasko D, et al. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 2010;133:713-726. doi: 10.1093/brain/awq008 PMID: 20157014
    • (2010) Brain , vol.133 , pp. 713-726
    • Hong, Z.1    Shi, M.2    Chung, K.A.3    Quinn, J.F.4    Peskind, E.R.5    Galasko, D.6
  • 34
    • 84860813308 scopus 로고    scopus 로고
    • Pathological correlates of gastrointestinal dysfunction in Parkinson's disease
    • 22048068
    • Cersosimo MG, Benarroch EE. Pathological correlates of gastrointestinal dysfunction in Parkinson's disease. Neurobiol Dis. 2012;46:559-564. doi: 10.1016/j.nbd.2011.10.014 PMID: 22048068
    • (2012) Neurobiol Dis. , vol.46 , pp. 559-564
    • Cersosimo, M.G.1    Benarroch, E.E.2
  • 35
    • 83455202793 scopus 로고    scopus 로고
    • A-synuclein misfolding and Parkinson's disease
    • 22024360
    • Breydo L, Wu JW, Uversky VN. A-synuclein misfolding and Parkinson's disease. Biochim Biophys Acta 2012;1822:261-285. doi: 10.1016/j.bbadis.2011.10.002 PMID: 22024360
    • (2012) Biochim Biophys Acta , vol.1822 , pp. 261-285
    • Breydo, L.1    Wu, J.W.2    Uversky, V.N.3
  • 36
    • 84879606955 scopus 로고    scopus 로고
    • α-Synuclein and protein degradation systems: A reciprocal relationship
    • 22941029
    • Xilouri M, Brekk OR, Stefanis L. α-Synuclein and protein degradation systems: a reciprocal relationship. Mol Neurobiol 2013;47:537-551. doi: 10.1007/s12035-012-8341-2 PMID: 22941029
    • (2013) Mol Neurobiol , vol.47 , pp. 537-551
    • Xilouri, M.1    Brekk, O.R.2    Stefanis, L.3
  • 37
    • 79951638042 scopus 로고    scopus 로고
    • Characterization of the non-fibrillar α-synuclein oligomers
    • 20858207
    • Hong DP, Han S, Fink AL, Uversky VN. Characterization of the non-fibrillar α-synuclein oligomers. Protein Pept Lett 2011;18:230-240. PMID: 20858207
    • (2011) Protein Pept Lett , vol.18 , pp. 230-240
    • Hong, D.P.1    Han, S.2    Fink, A.L.3    Uversky, V.N.4
  • 38
    • 84925950008 scopus 로고    scopus 로고
    • CSF biomarkers and clinical progression of Parkinson disease
    • 25411441
    • Hall S, Surova Y, Ohrfelt A, Zetterberg H, Lindqvist D, Hansson O. CSF biomarkers and clinical progression of Parkinson disease. Neurology 2015;84:57-63. doi: 10.1212/WNL.0000000000001098 PMID: 25411441
    • (2015) Neurology , vol.84 , pp. 57-63
    • Hall, S.1    Surova, Y.2    Ohrfelt, A.3    Zetterberg, H.4    Lindqvist, D.5    Hansson, O.6
  • 39
    • 84897840006 scopus 로고    scopus 로고
    • Cerebrospinal fluid α-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort
    • 24625392
    • Stewart T, Liu C, Ginghina C, Cain KC, Auinger P, Cholerton B, et al. Parkinson Study Group DATATOP Investigators. Cerebrospinal fluid α-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort. Am J Pathol 2014;184:966-975. doi: 10.1016/j.ajpath.2013.12.007 PMID: 24625392
    • (2014) Am J Pathol , vol.184 , pp. 966-975
    • Stewart, T.1    Liu, C.2    Ginghina, C.3    Cain, K.C.4    Auinger, P.5    Cholerton, B.6
  • 40
    • 84924190602 scopus 로고    scopus 로고
    • Parkinson disease with REM sleep behavior disorder: Features, α-synuclein, and inflammation
    • 25663225
    • Hu Y, Yu SY, Zuo LJ, Cao CJ, Wang F, Chen ZJ, et al. Parkinson disease with REM sleep behavior disorder: features, α-synuclein, and inflammation. Neurology 2015;84:888-894. doi: 10.1212/WNL. 0000000000001308 PMID: 25663225
    • (2015) Neurology , vol.84 , pp. 888-894
    • Hu, Y.1    Yu, S.Y.2    Zuo, L.J.3    Cao, C.J.4    Wang, F.5    Chen, Z.J.6
  • 41
    • 84906056706 scopus 로고    scopus 로고
    • Detection of diseaseassociated α-synuclein in the cerebrospinal fluid: A feasibility study
    • 25131945
    • Unterberger U, Lachmann I, Voigtlander T, Pirker W, Berghoff AS, Flach K, et al. Detection of diseaseassociated α-synuclein in the cerebrospinal fluid: a feasibility study. Clin Neuropathol. 2014;33(5):329-334. PMID: 25131945
    • (2014) Clin Neuropathol. , vol.33 , Issue.5 , pp. 329-334
    • Unterberger, U.1    Lachmann, I.2    Voigtlander, T.3    Pirker, W.4    Berghoff, A.S.5    Flach, K.6
  • 42
    • 84922074515 scopus 로고    scopus 로고
    • In vivo markers of Parkinson's disease and dementia with Lewy bodies: Current value of the 5G4 α-synuclein antibody
    • 25376537
    • Maetzler W, Pilotto A, Apel A, Deuschle C, Kuebart G, Heinzel S, et al. In vivo markers of Parkinson's disease and dementia with Lewy bodies: current value of the 5G4 α-synuclein antibody. Acta Neuropathol 2014;128:893-895. doi: 10.1007/s00401-014-1364-1 PMID: 25376537
    • (2014) Acta Neuropathol , vol.128 , pp. 893-895
    • Maetzler, W.1    Pilotto, A.2    Apel, A.3    Deuschle, C.4    Kuebart, G.5    Heinzel, S.6
  • 45
    • 84940055860 scopus 로고    scopus 로고
    • Peripheral synuclein tissue markers: A step closer to Parkinson's disease diagnosis
    • Tolosa E, Vilas Rolàn D. Peripheral synuclein tissue markers: a step closer to Parkinson's disease diagnosis. Brain 2015;138:2114-2125.
    • (2015) Brain , vol.138 , pp. 2114-2125
    • Tolosa, E.1    Vilas Rolàn, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.