메뉴 건너뛰기




Volumn 64, Issue 3, 2015, Pages 746-759

Deletion of both rab-GTPase-activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; MESSENGER RNA; RAB PROTEIN; TBC1D1 PROTEIN; TBC1D4 PROTEIN; UNCLASSIFIED DRUG; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; AICA RIBONUCLEOTIDE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; NUCLEAR PROTEIN; RIBONUCLEOTIDE; TBC1D1 PROTEIN, MOUSE; TBC1D4 PROTEIN, MOUSE;

EID: 84962050593     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0368     Document Type: Article
Times cited : (71)

References (53)
  • 1
    • 84861444859 scopus 로고    scopus 로고
    • Regulation of glucose transport by insulin: Traffic control of GLUT4
    • Leto D, Saltiel AR. Regulation of glucose transport by insulin: traffic control of GLUT4. Nat Rev Mol Cell Biol 2012;13:383-396
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 383-396
    • Leto, D.1    Saltiel, A.R.2
  • 2
    • 0028518842 scopus 로고
    • Subcellular localization and trafficking of the GLUT4 glucose transporter isoform in insulin-responsive cells
    • Holman GD, Cushman SW. Subcellular localization and trafficking of the GLUT4 glucose transporter isoform in insulin-responsive cells. Bioessays 1994; 16:753-759
    • (1994) Bioessays , vol.16 , pp. 753-759
    • Holman, G.D.1    Cushman, S.W.2
  • 3
    • 0037677096 scopus 로고    scopus 로고
    • Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation
    • Sano H, Kane S, Sano E, et al. Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. J Biol Chem 2003;278:14599-14602
    • (2003) J Biol Chem , vol.278 , pp. 14599-14602
    • Sano, H.1    Kane, S.2    Sano, E.3
  • 4
    • 34247148430 scopus 로고    scopus 로고
    • Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1
    • Roach WG, Chavez JA, Mîinea CP, Lienhard GE. Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1. Biochem J 2007;403:353-358
    • (2007) Biochem J , vol.403 , pp. 353-358
    • Roach, W.G.1    Chavez, J.A.2    Mîinea, C.P.3    Lienhard, G.E.4
  • 5
    • 33747039008 scopus 로고    scopus 로고
    • Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle
    • Kramer HF, Witczak CA, Fujii N, et al. Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle. Diabetes 2006;55:2067-2076
    • (2006) Diabetes , vol.55 , pp. 2067-2076
    • Kramer, H.F.1    Witczak, C.A.2    Fujii, N.3
  • 6
    • 38749110036 scopus 로고    scopus 로고
    • Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators
    • Chen S, Murphy J, Toth R, Campbell DG, Morrice NA, Mackintosh C. Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators. Biochem J 2008;409:449-459
    • (2008) Biochem J , vol.409 , pp. 449-459
    • Chen, S.1    Murphy, J.2    Toth, R.3    Campbell, D.G.4    Morrice, N.A.5    Mackintosh, C.6
  • 7
    • 50349099779 scopus 로고    scopus 로고
    • Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic
    • Sakamoto K, Holman GD. Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic. Am J Physiol Endocrinol Metab 2008;295:E29-E37
    • (2008) Am J Physiol Endocrinol Metab , vol.295 , pp. E29-E37
    • Sakamoto, K.1    Holman, G.D.2
  • 8
    • 77953195622 scopus 로고    scopus 로고
    • TBC1D1 regulates insulin-and contraction-induced glucose transport in mouse skeletal muscle
    • An D, Toyoda T, Taylor EB, et al. TBC1D1 regulates insulin-and contraction-induced glucose transport in mouse skeletal muscle. Diabetes 2010;59:1358-1365
    • (2010) Diabetes , vol.59 , pp. 1358-1365
    • An, D.1    Toyoda, T.2    Taylor, E.B.3
  • 9
    • 65349122785 scopus 로고    scopus 로고
    • Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle
    • Funai K, Cartee GD. Inhibition of contraction-stimulated AMP-activated protein kinase inhibits contraction-stimulated increases in PAS-TBC1D1 and glucose transport without altering PAS-AS160 in rat skeletal muscle. Diabetes 2009;58:1096-1104
    • (2009) Diabetes , vol.58 , pp. 1096-1104
    • Funai, K.1    Cartee, G.D.2
  • 10
    • 55049131588 scopus 로고    scopus 로고
    • Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity
    • Chadt A, Leicht K, Deshmukh A, et al. Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity. Nat Genet 2008; 40:1354-1359
    • (2008) Nat Genet , vol.40 , pp. 1354-1359
    • Chadt, A.1    Leicht, K.2    Deshmukh, A.3
  • 11
    • 33748745768 scopus 로고    scopus 로고
    • TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition
    • Stone S, Abkevich V, Russell DL, et al. TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition. Hum Mol Genet 2006;15:2709-2720
    • (2006) Hum Mol Genet , vol.15 , pp. 2709-2720
    • Stone, S.1    Abkevich, V.2    Russell, D.L.3
  • 12
    • 44849112532 scopus 로고    scopus 로고
    • R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population
    • Meyre D, Farge M, Lecoeur C, et al. R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population. Hum Mol Genet 2008;17:1798-1802
    • (2008) Hum Mol Genet , vol.17 , pp. 1798-1802
    • Meyre, D.1    Farge, M.2    Lecoeur, C.3
  • 13
    • 67249108808 scopus 로고    scopus 로고
    • A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia
    • Dash S, Sano H, Rochford JJ, et al. A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia. Proc Natl Acad Sci U S A 2009;106:9350-9355
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9350-9355
    • Dash, S.1    Sano, H.2    Rochford, J.J.3
  • 14
    • 84871447109 scopus 로고    scopus 로고
    • AS160 deficiency causes wholebody insulin resistance via composite effects in multiple tissues
    • Wang HY, Ducommun S, Quan C, et al. AS160 deficiency causes wholebody insulin resistance via composite effects in multiple tissues. Biochem J 2013;449:479-489
    • (2013) Biochem J , vol.449 , pp. 479-489
    • Wang, H.Y.1    Ducommun, S.2    Quan, C.3
  • 15
    • 84865152468 scopus 로고    scopus 로고
    • The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism
    • Szekeres F, Chadt A, Tom RZ, et al. The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism. Am J Physiol Endocrinol Metab 2012;303:E524-E533
    • (2012) Am J Physiol Endocrinol Metab , vol.303 , pp. E524-E533
    • Szekeres, F.1    Chadt, A.2    Tom, R.Z.3
  • 16
    • 26844573782 scopus 로고    scopus 로고
    • AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain
    • Mîinea CP, Sano H, Kane S, et al. AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain. Biochem J 2005;391:87-93
    • (2005) Biochem J , vol.391 , pp. 87-93
    • Mîinea, C.P.1    Sano, H.2    Kane, S.3
  • 17
    • 84875170598 scopus 로고    scopus 로고
    • Regulatory mode shift of Tbc1d1 is required for acquisition of insulin-responsive GLUT4-trafficking activity
    • Hatakeyama H, Kanzaki M. Regulatory mode shift of Tbc1d1 is required for acquisition of insulin-responsive GLUT4-trafficking activity. Mol Biol Cell 2013;24: 809-817
    • (2013) Mol Biol Cell , vol.24 , pp. 809-817
    • Hatakeyama, H.1    Kanzaki, M.2
  • 18
    • 79955773722 scopus 로고    scopus 로고
    • AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane
    • Koumanov F, Richardson JD, Murrow BA, Holman GD. AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane. J Biol Chem 2011;286:16574-16582
    • (2011) J Biol Chem , vol.286 , pp. 16574-16582
    • Koumanov, F.1    Richardson, J.D.2    Murrow, B.A.3    Holman, G.D.4
  • 19
    • 84871902200 scopus 로고    scopus 로고
    • The Rab GAPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes
    • Tan SX, Ng Y, Burchfield JG, et al. The Rab GAPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes. Mol Cell Biol 2012;32:4946-4959
    • (2012) Mol Cell Biol , vol.32 , pp. 4946-4959
    • Tan, S.X.1    Ng, Y.2    Burchfield, J.G.3
  • 20
    • 78650549552 scopus 로고    scopus 로고
    • Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells
    • Sun Y, Bilan PJ, Liu Z, Klip A. Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells. Proc Natl Acad Sci U S A 2010; 107:19909-19914
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 19909-19914
    • Sun, Y.1    Bilan, P.J.2    Liu, Z.3    Klip, A.4
  • 21
    • 79960665062 scopus 로고    scopus 로고
    • Loss of AS160 Akt substrate causes Glut4 protein to accumulate in compartments that are primed for fusion in basal adipocytes
    • Brewer PD, Romenskaia I, Kanow MA, Mastick CC. Loss of AS160 Akt substrate causes Glut4 protein to accumulate in compartments that are primed for fusion in basal adipocytes. J Biol Chem 2011;286:26287-26297
    • (2011) J Biol Chem , vol.286 , pp. 26287-26297
    • Brewer, P.D.1    Romenskaia, I.2    Kanow, M.A.3    Mastick, C.C.4
  • 22
    • 28544435205 scopus 로고    scopus 로고
    • Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein
    • Eguez L, Lee A, Chavez JA, et al. Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein. Cell Metab 2005;2:263-272
    • (2005) Cell Metab , vol.2 , pp. 263-272
    • Eguez, L.1    Lee, A.2    Chavez, J.A.3
  • 23
    • 84884692647 scopus 로고    scopus 로고
    • Conventional knockout of Tbc1d1 in mice impairs insulin-and AICAR-stimulated glucose uptake in skeletal muscle
    • Dokas J, Chadt A, Nolden T, et al. Conventional knockout of Tbc1d1 in mice impairs insulin-and AICAR-stimulated glucose uptake in skeletal muscle. Endocrinology 2013;154:3502-3514
    • (2013) Endocrinology , vol.154 , pp. 3502-3514
    • Dokas, J.1    Chadt, A.2    Nolden, T.3
  • 24
    • 84869195388 scopus 로고    scopus 로고
    • Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis
    • Lansey MN, Walker NN, Hargett SR, Stevens JR, Keller SR. Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis. Am J Physiol Endocrinol Metab 2012;303:E1273-E1286
    • (2012) Am J Physiol Endocrinol Metab , vol.303 , pp. E1273-E1286
    • Lansey, M.N.1    Walker, N.N.2    Hargett, S.R.3    Stevens, J.R.4    Keller, S.R.5
  • 25
    • 0030959717 scopus 로고    scopus 로고
    • Speed congenics: A classic technique in the fast lane (relatively speaking)
    • Wakeland E, Morel L, Achey K, Yui M, Longmate J. Speed congenics: a classic technique in the fast lane (relatively speaking). Immunol Today 1997;18: 472-477
    • (1997) Immunol Today , vol.18 , pp. 472-477
    • Wakeland, E.1    Morel, L.2    Achey, K.3    Yui, M.4    Longmate, J.5
  • 26
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25:402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 27
    • 0026128307 scopus 로고
    • Table of nonprotein respiratory quotient: An update
    • Péronnet F, Massicotte D. Table of nonprotein respiratory quotient: an update. Can J Sport Sci 1991;16:23-29
    • (1991) Can J Sport Sci , vol.16 , pp. 23-29
    • Péronnet, F.1    Massicotte, D.2
  • 28
    • 0016257489 scopus 로고
    • A comparison of three methods of glycogen measurement in tissues
    • Passonneau JV, Lauderdale VR. A comparison of three methods of glycogen measurement in tissues. Anal Biochem 1974;60:405-412
    • (1974) Anal Biochem , vol.60 , pp. 405-412
    • Passonneau, J.V.1    Lauderdale, V.R.2
  • 29
    • 0021138774 scopus 로고
    • The fate of labelled glucose molecules in the rat adipocyte. Dependence on glucose concentration
    • Gliemann J, Rees WD, Foley JA. The fate of labelled glucose molecules in the rat adipocyte. Dependence on glucose concentration. Biochim Biophys Acta 1984;804:68-76
    • (1984) Biochim Biophys Acta , vol.804 , pp. 68-76
    • Gliemann, J.1    Rees, W.D.2    Foley, J.A.3
  • 30
    • 0032504208 scopus 로고    scopus 로고
    • Endocytosis of the glucose transporter GLUT4 is mediated by the GTPase dynamin
    • Al-Hasani H, Hinck CS, Cushman SW. Endocytosis of the glucose transporter GLUT4 is mediated by the GTPase dynamin. J Biol Chem 1998;273: 17504-17510
    • (1998) J Biol Chem , vol.273 , pp. 17504-17510
    • Al-Hasani, H.1    Hinck, C.S.2    Cushman, S.W.3
  • 31
    • 0035932512 scopus 로고    scopus 로고
    • Synthesis of biotinylated bis(D-glucose) derivatives for glucose transporter photoaffinity labelling
    • Hashimoto M, Hatanaka Y, Yang J, Dhesi J, Holman GD. Synthesis of biotinylated bis(D-glucose) derivatives for glucose transporter photoaffinity labelling. Carbohydr Res 2001;331:119-127
    • (2001) Carbohydr Res , vol.331 , pp. 119-127
    • Hashimoto, M.1    Hatanaka, Y.2    Yang, J.3    Dhesi, J.4    Holman, G.D.5
  • 32
    • 0028817838 scopus 로고
    • Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles
    • Keller SR, Scott HM, Mastick CC, Aebersold R, Lienhard GE. Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles. J Biol Chem 1995;270:23612-23618
    • (1995) J Biol Chem , vol.270 , pp. 23612-23618
    • Keller, S.R.1    Scott, H.M.2    Mastick, C.C.3    Aebersold, R.4    Lienhard, G.E.5
  • 33
    • 78650897555 scopus 로고    scopus 로고
    • Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking
    • Chen S, Wasserman DH, MacKintosh C, Sakamoto K. Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking. Cell Metab 2011;13: 68-79
    • (2011) Cell Metab , vol.13 , pp. 68-79
    • Chen, S.1    Wasserman, D.H.2    MacKintosh, C.3    Sakamoto, K.4
  • 34
    • 84891020337 scopus 로고    scopus 로고
    • Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells
    • Rütti S, Arous C, Nica AC, Kanzaki M, Halban PA, Bouzakri K. Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells. FEBS Lett 2014;588:15-20
    • (2014) FEBS Lett , vol.588 , pp. 15-20
    • Rütti, S.1    Arous, C.2    Nica, A.C.3    Kanzaki, M.4    Halban, P.A.5    Bouzakri, K.6
  • 35
    • 48449102210 scopus 로고    scopus 로고
    • Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells
    • Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA. Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells. Diabetes 2008;57: 1195-1204
    • (2008) Diabetes , vol.57 , pp. 1195-1204
    • Bouzakri, K.1    Ribaux, P.2    Tomas, A.3    Parnaud, G.4    Rickenbach, K.5    Halban, P.A.6
  • 36
    • 15244358817 scopus 로고    scopus 로고
    • GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization
    • Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB. GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization. J Clin Invest 2004;114:1666-1675
    • (2004) J Clin Invest , vol.114 , pp. 1666-1675
    • Kotani, K.1    Peroni, O.D.2    Minokoshi, Y.3    Boss, O.4    Kahn, B.B.5
  • 38
    • 0031561379 scopus 로고    scopus 로고
    • Trafficking kinetics of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes
    • Ross SA, Herbst JJ, Keller SR, Lienhard GE. Trafficking kinetics of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes. Biochem Biophys Res Commun 1997;239:247-251
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 247-251
    • Ross, S.A.1    Herbst, J.J.2    Keller, S.R.3    Lienhard, G.E.4
  • 39
    • 0342684587 scopus 로고    scopus 로고
    • Vp165 and GLUT4 share similar vesicle pools along their trafficking pathways in rat adipose cells
    • Malide D, St-Denis JF, Keller SR, Cushman SW. Vp165 and GLUT4 share similar vesicle pools along their trafficking pathways in rat adipose cells. FEBS Lett 1997;409:461-468
    • (1997) FEBS Lett , vol.409 , pp. 461-468
    • Malide, D.1    St-Denis, J.F.2    Keller, S.R.3    Cushman, S.W.4
  • 40
    • 33749365543 scopus 로고    scopus 로고
    • Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase
    • Peck GR, Ye S, Pham V, et al. Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase. Mol Endocrinol 2006;20:2576-2583
    • (2006) Mol Endocrinol , vol.20 , pp. 2576-2583
    • Peck, G.R.1    Ye, S.2    Pham, V.3
  • 41
    • 77953531316 scopus 로고    scopus 로고
    • Insulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesicles
    • Jordens I, Molle D, Xiong W, Keller SR, McGraw TE. Insulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesicles. Mol Biol Cell 2010;21:2034-2044
    • (2010) Mol Biol Cell , vol.21 , pp. 2034-2044
    • Jordens, I.1    Molle, D.2    Xiong, W.3    Keller, S.R.4    McGraw, T.E.5
  • 42
    • 0032728265 scopus 로고    scopus 로고
    • Overexpression of the glucose transporter GLUT4 in adipose cells interferes with insulin-stimulated translocation
    • Al-Hasani H, Yver DR, Cushman SW. Overexpression of the glucose transporter GLUT4 in adipose cells interferes with insulin-stimulated translocation. FEBS Lett 1999;460:338-342
    • (1999) FEBS Lett , vol.460 , pp. 338-342
    • Al-Hasani, H.1    Yver, D.R.2    Cushman, S.W.3
  • 43
    • 0033834248 scopus 로고    scopus 로고
    • Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance
    • Zisman A, Peroni OD, Abel ED, et al. Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance. Nat Med 2000;6:924-928
    • (2000) Nat Med , vol.6 , pp. 924-928
    • Zisman, A.1    Peroni, O.D.2    Abel, E.D.3
  • 44
    • 0035825643 scopus 로고    scopus 로고
    • Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
    • Abel ED, Peroni O, Kim JK, et al. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature 2001;409: 729-733
    • (2001) Nature , vol.409 , pp. 729-733
    • Abel, E.D.1    Peroni, O.2    Kim, J.K.3
  • 45
    • 0028817712 scopus 로고
    • Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice
    • Ren JM, Marshall BA, Mueckler MM, McCaleb M, Amatruda JM, Shulman GI. Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice. J Clin Invest 1995;95:429-432
    • (1995) J Clin Invest , vol.95 , pp. 429-432
    • Ren, J.M.1    Marshall, B.A.2    Mueckler, M.M.3    McCaleb, M.4    Amatruda, J.M.5    Shulman, G.I.6
  • 46
    • 57049184703 scopus 로고    scopus 로고
    • Muscle cells engage Rab8A and myosin Vb in insulindependent GLUT4 translocation
    • Ishikura S, Klip A. Muscle cells engage Rab8A and myosin Vb in insulindependent GLUT4 translocation. Am J Physiol Cell Physiol 2008;295:C1016-C1025
    • (2008) Am J Physiol Cell Physiol , vol.295 , pp. C1016-C1025
    • Ishikura, S.1    Klip, A.2
  • 47
    • 27144504389 scopus 로고    scopus 로고
    • Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism
    • Kim YB, Peroni OD, Aschenbach WG, et al. Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism. Mol Cell Biol 2005;25:9713-9723
    • (2005) Mol Cell Biol , vol.25 , pp. 9713-9723
    • Kim, Y.B.1    Peroni, O.D.2    Aschenbach, W.G.3
  • 50
    • 84898758717 scopus 로고    scopus 로고
    • Myosin Va mediates Rab8Aregulated GLUT4 vesicle exocytosis in insulin-stimulated muscle cells
    • Sun Y, Chiu TT, Foley KP, Bilan PJ, Klip A. Myosin Va mediates Rab8Aregulated GLUT4 vesicle exocytosis in insulin-stimulated muscle cells. Mol Biol Cell 2014;25:1159-1170
    • (2014) Mol Biol Cell , vol.25 , pp. 1159-1170
    • Sun, Y.1    Chiu, T.T.2    Foley, K.P.3    Bilan, P.J.4    Klip, A.5
  • 51
    • 84866347107 scopus 로고    scopus 로고
    • Rab10 and myosin-Va mediate insulinstimulated GLUT4 storage vesicle translocation in adipocytes
    • Chen Y, Wang Y, Zhang J, et al. Rab10 and myosin-Va mediate insulinstimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol 2012; 198:545-560
    • (2012) J Cell Biol , vol.198 , pp. 545-560
    • Chen, Y.1    Wang, Y.2    Zhang, J.3
  • 52
    • 84878666414 scopus 로고    scopus 로고
    • A role for Rab14 in the endocytic trafficking of GLUT4 in 3T3-L1 adipocytes
    • Reed SE, Hodgson LR, Song S, et al. A role for Rab14 in the endocytic trafficking of GLUT4 in 3T3-L1 adipocytes. J Cell Sci 2013;126: 1931-1941
    • (2013) J Cell Sci , vol.126 , pp. 1931-1941
    • Reed, S.E.1    Hodgson, L.R.2    Song, S.3
  • 53
    • 84882762459 scopus 로고    scopus 로고
    • Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs
    • Sadacca LA, Bruno J, Wen J, Xiong W, McGraw TE. Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs. Mol Biol Cell 2013;24:2544-2557
    • (2013) Mol Biol Cell , vol.24 , pp. 2544-2557
    • Sadacca, L.A.1    Bruno, J.2    Wen, J.3    Xiong, W.4    McGraw, T.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.