Cross-comparison of exome analysis, next-generation sequencing of amplicons, and the iPLEX® ADME PGx panel for pharmacogenomic profiling

Frontiers in Pharmacology

Volumn 7, Issue JAN, 2016, Pages

  Chua, Eng Wee ^a,b   Cree, Simone L ^a   Ton, Kim N T ^a   Lehnert, Klaus ^c   Shepherd, Phillip ^d   Helsby, Nuala ^e   Kennedy, Martin A ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d UNIVERSITY OF AUCKLAND   (New Zealand)

^e UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Multiplexed genotyping panel; Next generation amplicon sequencing; Pharmacogenomic profiling; Variant quality score recalibration; Whole exome sequencing

Indexed keywords

AMPLICON; ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; CYP2C19 GENE; CYP2D6 GENE; EXOME; GENE; GENETIC ANALYZER; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HUMAN; HUMAN CELL; INDEL MUTATION; INTERMETHOD COMPARISON; NEXT GENERATION SEQUENCING; PHARMACOGENOMICS; SENSITIVITY ANALYSIS;

EID: 84962016912     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2016.00001     Document Type: Article

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