An experimental and computational analysis on the differential role of the positional isomers of symmetric bis-2-(pyridyl)-1H-benzimidazoles as DNA binding agents

Journal of Organic Chemistry

Volumn 72, Issue 6, 2007, Pages 1912-1923

  Chaudhuri, Padmaparna ^a   Ganguly, Bishwajit ^b   Bhattacharya, Santanu ^a,c  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b CSIR CENTRAL SALT AND MARINE CHEMICALS RESEARCH INSTITUTE   (India)

^c JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DERIVATIVES; DNA SEQUENCES; ISOMERS; LIGANDS; MOLECULAR RECOGNITION; PYRIDINE; SYNTHESIS (CHEMICAL);

BENZIMIDAZOLE UNITS; BINDING AFFINITIES; CONFORMATIONAL RIGIDITY; DNA BINDING AGENTS;

NITROGEN COMPOUNDS;

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; BENZIMIDAZOLE DERIVATIVE; DOUBLE STRANDED DNA; PIBENZIMOL; PYRIDINE DERIVATIVE;

AB INITIO CALCULATION; ARTICLE; BINDING AFFINITY; CHEMICAL ANALYSIS; CIRCULAR DICHROISM; DENSITY FUNCTIONAL THEORY; DNA BINDING; DNA DENATURATION; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; ISOMER; LIGAND BINDING; MOLECULAR RECOGNITION; PKA;

EID: 84961983597     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0619433     Document Type: Article

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