Axial-selective H/D exchange of glycine-derived 1 H -benzo[ e ][1,4]diazepin-2(3 H)-ones: Kinetic and computational studies of enantiomerization

Journal of Organic Chemistry

Volumn 75, Issue 19, 2010, Pages 6588-6594

  Carlier, Paul R ^a   Sun, Yang Sheng ^a   Hsu, Danny C ^a   Chen, Qiao Hong ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COALESCENCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

COMPUTATIONAL STUDIES; DENSITY FUNCTIONAL THEORY CALCULATIONS; ELEVATED TEMPERATURE; ENANTIOMERIZATION; ENANTIOMERIZATION BARRIERS; H NMR SPECTROSCOPY; H/D EXCHANGE; ISOTOPOMERS; ROOM TEMPERATURE;

DENSITY FUNCTIONAL THEORY;

1 ISOPROPYL 7,9 DIMETHYL 5 PHENYL 1H BENZO [E] [1,4] DIAZEPIN 2(3H) ONE; 1,7,9 TRIMETHYL 5 PHENYL 1H BENZO [E] [1,4] DIAZEPIN 2(3H) ONE; 1H BENZO [E] [1,4] DIAZEPIN 2(3H) ONE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; CARBON; GLYCINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DENSITY FUNCTIONAL THEORY; ENANTIOMER; KINETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; ROOM TEMPERATURE; SYNTHESIS;

EID: 84961978359     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo1010608     Document Type: Article

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