-
2
-
-
79955062821
-
Spontaneous neurotransmission: An independent pathway for neuronal signaling?
-
Kavalali, E. T. et al. Spontaneous Neurotransmission: An Independent Pathway for Neuronal Signaling? Physiology 26, 45-53 (2011).
-
(2011)
Physiology
, vol.26
, pp. 45-53
-
-
Kavalali, E.T.1
-
3
-
-
33646504383
-
Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis
-
Sutton, M. A. et al. Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis. Cell 125, 785-799 (2006).
-
(2006)
Cell
, vol.125
, pp. 785-799
-
-
Sutton, M.A.1
-
4
-
-
84899621429
-
Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission
-
Liu, H. et al. Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission. Nat. Neurosci. 17, 670-677 (2014).
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 670-677
-
-
Liu, H.1
-
5
-
-
46449093538
-
How does synaptotagmin trigger neurotransmitter release?
-
Chapman, E. R. How does synaptotagmin trigger neurotransmitter release? Annu. Rev. Biochem. 77, 615-641 (2008).
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 615-641
-
-
Chapman, E.R.1
-
6
-
-
0027974130
-
Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants
-
Littleton, J. T., Stern, M., Perin, M. & Bellen, H. J. Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants. Proc. Natl Acad. Sci. USA 91, 10888-10892 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 10888-10892
-
-
Littleton, J.T.1
Stern, M.2
Perin, M.3
Bellen, H.J.4
-
9
-
-
0035924571
-
Three-dimensional structure of the synaptotagmin 1 C2Bdomain: Synaptotagmin 1 as a phospholipid binding machine
-
Fernandez, I. et al. Three-dimensional structure of the synaptotagmin 1 C2Bdomain: synaptotagmin 1 as a phospholipid binding machine. Neuron 32, 1057-1069 (2001).
-
(2001)
Neuron
, vol.32
, pp. 1057-1069
-
-
Fernandez, I.1
-
10
-
-
0027517462
-
A protein assembly-disassembly pathway in-vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
-
Sollner, T., Bennett, M. K., Whiteheart, S. W., Scheller, R. H. & Rothman, J. E. A protein assembly-disassembly pathway in-vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 75, 409-418 (1993).
-
(1993)
Cell
, vol.75
, pp. 409-418
-
-
Sollner, T.1
Bennett, M.K.2
Whiteheart, S.W.3
Scheller, R.H.4
Rothman, J.E.5
-
12
-
-
0032549708
-
SNAREpins: Minimal machinery for membrane fusion
-
Weber, T. et al. SNAREpins: minimal machinery for membrane fusion. Cell 92, 759-772 (1998).
-
(1998)
Cell
, vol.92
, pp. 759-772
-
-
Weber, T.1
-
13
-
-
1942520207
-
2+-regulated membrane fusion by synaptotagmin and SNAREs
-
2+-regulated membrane fusion by synaptotagmin and SNAREs. Science 304, 435-438 (2004).
-
(2004)
Science
, vol.304
, pp. 435-438
-
-
Tucker, W.C.1
Weber, T.2
Chapman, E.R.3
-
15
-
-
79960053907
-
Mechanism and function of synaptotagmin-mediated membrane apposition
-
Hui, E. et al. Mechanism and function of synaptotagmin-mediated membrane apposition. Nat. Struct. Mol. Biol. 18, 813-821 (2011).
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 813-821
-
-
Hui, E.1
-
17
-
-
77955638309
-
Regulation of exocytosis and fusion pores by synaptotagmin-effector interactions
-
Zhang, Z., Hui, E., Chapman, E. R. & Jackson, M. B. Regulation of exocytosis and fusion pores by synaptotagmin-effector interactions. Mol. Biol. Cell 21, 2821-2831 (2010).
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2821-2831
-
-
Zhang, Z.1
Hui, E.2
Chapman, E.R.3
Jackson, M.B.4
-
19
-
-
84883430611
-
Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering
-
Mohrmann, R. et al. Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering. J. Neurosci. 33, 14417-14430 (2013).
-
(2013)
J. Neurosci.
, vol.33
, pp. 14417-14430
-
-
Mohrmann, R.1
-
21
-
-
0026631563
-
Synaptotagmin: A calcium sensor on the synaptic vesicle surface
-
Brose, N., Petrenko, A. G., Sudhof, T. C. & Jahn, R. Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science 256, 1021-1025 (1992).
-
(1992)
Science
, vol.256
, pp. 1021-1025
-
-
Brose, N.1
Petrenko, A.G.2
Sudhof, T.C.3
Jahn, R.4
-
22
-
-
0032577067
-
2+-binding loop of synaptotagmin with lipid bilayers
-
2+-binding loop of synaptotagmin with lipid bilayers. J. Biol. Chem. 273, 13995-14001 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13995-14001
-
-
Chapman, E.R.1
Davis, A.F.2
-
23
-
-
0842291506
-
PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane
-
Bai, J., Tucker, W. C. & Chapman, E. R. PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane. Nat. Struct. Mol. Biol. 11, 36-44 (2004).
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 36-44
-
-
Bai, J.1
Tucker, W.C.2
Chapman, E.R.3
-
25
-
-
34249933061
-
How synaptotagmin promotes membrane fusion
-
Martens, S., Kozlov, M. M. & McMahon, H. T. How synaptotagmin promotes membrane fusion. Science 316, 1205-1208 (2007).
-
(2007)
Science
, vol.316
, pp. 1205-1208
-
-
Martens, S.1
Kozlov, M.M.2
McMahon, H.T.3
-
27
-
-
84923361538
-
2+ measured with a novel membrane distance ruler
-
2+ measured with a novel membrane distance ruler. Nat. Commun 5, 5859 (2014).
-
(2014)
Nat. Commun
, vol.5
, pp. 5859
-
-
Lin, C.C.1
-
30
-
-
33644804207
-
2+dependent multivalent binding of synaptotagmin-1 to phospholipids
-
2+dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat. Struct. Mol. Biol. 13, 209-217 (2006).
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 209-217
-
-
Arac, D.1
-
32
-
-
56749117908
-
Conformation and membrane position of the region linking the two C2 domains in synaptotagmin 1 by site-directed spin labeling
-
Huang, H. & Cafiso, D. S. Conformation and membrane position of the region linking the two C2 domains in synaptotagmin 1 by site-directed spin labeling. Biochemistry 47, 12380-12388 (2008).
-
(2008)
Biochemistry
, vol.47
, pp. 12380-12388
-
-
Huang, H.1
Cafiso, D.S.2
-
33
-
-
0028097921
-
The structure and function of proline-rich regions in proteins
-
Williamson, M. P. The structure and function of proline-rich regions in proteins. Biochem. J. 297 (Pt 2) 249-260 (1994).
-
(1994)
Biochem. J.
, vol.297
, pp. 249-260
-
-
Williamson, M.P.1
-
35
-
-
84859522695
-
Structural distributions from single-molecule measurements as a tool for molecular mechanics
-
Hanson, J. A., Brokaw, J., Hayden, C. C., Chu, J. W. & Yang, H. Structural distributions from single-molecule measurements as a tool for molecular mechanics. Chem. Phys. 396, 61-71 (2012).
-
(2012)
Chem. Phys.
, vol.396
, pp. 61-71
-
-
Hanson, J.A.1
Brokaw, J.2
Hayden, C.C.3
Chu, J.W.4
Yang, H.5
-
36
-
-
14544283620
-
Polyproline and the "spectroscopic ruler" revisited with single-molecule fluorescence
-
Schuler, B., Lipman, E. A., Steinbach, P. J., Kumke, M. & Eaton, W. A. Polyproline and the "spectroscopic ruler" revisited with single-molecule fluorescence. Proc. Natl Acad. Sci. USA 102, 2754-2759 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 2754-2759
-
-
Schuler, B.1
Lipman, E.A.2
Steinbach, P.J.3
Kumke, M.4
Eaton, W.A.5
-
37
-
-
36849083388
-
Probing polyproline structure and dynamics by photoinduced electron transfer provides evidence for deviations from a regular polyproline type II helix
-
Doose, S., Neuweiler, H., Barsch, H. & Sauer, M. Probing polyproline structure and dynamics by photoinduced electron transfer provides evidence for deviations from a regular polyproline type II helix. Proc. Natl Acad. Sci. USA 104, 17400-17405 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 17400-17405
-
-
Doose, S.1
Neuweiler, H.2
Barsch, H.3
Sauer, M.4
-
38
-
-
50549084252
-
2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivo
-
2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivo. J. Neurosci. 28, 7458-7466 (2008).
-
(2008)
J. Neurosci.
, vol.28
, pp. 7458-7466
-
-
Paddock, B.E.1
Striegel, A.R.2
Hui, E.3
Chapman, E.R.4
Reist, N.E.5
-
39
-
-
33748442138
-
2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I
-
2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I. Biophys. J. 91, 1767-1777 (2006).
-
(2006)
Biophys. J.
, vol.91
, pp. 1767-1777
-
-
Hui, E.1
Bai, J.2
Chapman, E.R.3
-
40
-
-
0030175394
-
Definition of the readily releasable pool of vesicles at hippocampal synapses
-
Rosenmund, C. & Stevens, C. F. Definition of the readily releasable pool of vesicles at hippocampal synapses. Neuron 16, 1197-1207 (1996).
-
(1996)
Neuron
, vol.16
, pp. 1197-1207
-
-
Rosenmund, C.1
Stevens, C.F.2
-
41
-
-
67049114053
-
Autapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I
-
Liu, H., Dean, C., Arthur, C. P., Dong, M. & Chapman, E. R. Autapses and networks of hippocampal neurons exhibit distinct synaptic transmission phenotypes in the absence of synaptotagmin I. J. Neurosci. 29, 7395-7403 (2009).
-
(2009)
J. Neurosci.
, vol.29
, pp. 7395-7403
-
-
Liu, H.1
Dean, C.2
Arthur, C.P.3
Dong, M.4
Chapman, E.R.5
-
42
-
-
78049441725
-
Distance mapping in proteins using fluorescence spectroscopy: The tryptophan-induced quenching (TrIQ) method
-
Mansoor, S. E., DeWitt, M. A. & Farrens, D. L. Distance mapping in proteins using fluorescence spectroscopy: the tryptophan-induced quenching (TrIQ) method. Biochemistry 49, 9722-9731 (2010).
-
(2010)
Biochemistry
, vol.49
, pp. 9722-9731
-
-
Mansoor, S.E.1
DeWitt, M.A.2
Farrens, D.L.3
-
44
-
-
33747453911
-
Position of synaptotagmin I at the membrane interface: Cooperative interactions of tandem C2 domains
-
Herrick, D. Z., Sterbling, S., Rasch, K. A., Hinderliter, A. & Cafiso, D. S. Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains. Biochemistry 45, 9668-9674 (2006).
-
(2006)
Biochemistry
, vol.45
, pp. 9668-9674
-
-
Herrick, D.Z.1
Sterbling, S.2
Rasch, K.A.3
Hinderliter, A.4
Cafiso, D.S.5
-
45
-
-
84882767998
-
Prevalent mechanism of membrane bridging by synaptotagmin-1
-
Seven, A. B., Brewer, K. D., Shi, L., Jiang, Q. X. & Rizo, J. Prevalent mechanism of membrane bridging by synaptotagmin-1. Proc. Natl Acad. Sci. USA 110, E3243-E3252 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. E3243-E3252
-
-
Seven, A.B.1
Brewer, K.D.2
Shi, L.3
Jiang, Q.X.4
Rizo, J.5
-
46
-
-
0842291506
-
PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane
-
Bai, J. H., Tucker, W. C. & Chapman, E. R. PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane. Nat. Struct. Mol. Biol. 11, 36-44 (2004).
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 36-44
-
-
Bai, J.H.1
Tucker, W.C.2
Chapman, E.R.3
-
47
-
-
0025270739
-
Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C
-
Perin, M. S., Fried, V. A., Mignery, G. A., Jahn, R. & Sudhof, T. C. Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C. Nature 345, 260-263 (1990).
-
(1990)
Nature
, vol.345
, pp. 260-263
-
-
Perin, M.S.1
Fried, V.A.2
Mignery, G.A.3
Jahn, R.4
Sudhof, T.C.5
-
48
-
-
0034605096
-
2+-sensing module essential for exocytosis
-
2+-sensing module essential for exocytosis. J. Cell Biol. 150, 1125-1136 (2000).
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1125-1136
-
-
Desai, R.C.1
-
49
-
-
0024520745
-
Site-directed mutagenesis by overlap extension using the polymerase chain-reaction
-
Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K. & Pease, L. R. Site-directed mutagenesis by overlap extension using the polymerase chain-reaction. Gene 77, 51-59 (1989).
-
(1989)
Gene
, vol.77
, pp. 51-59
-
-
Ho, S.N.1
Hunt, H.D.2
Horton, R.M.3
Pullen, J.K.4
Pease, L.R.5
-
50
-
-
67349113528
-
Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release
-
Dean, C. et al. Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release. Nat. Neurosci. 12, 767-776 (2009).
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 767-776
-
-
Dean, C.1
-
51
-
-
0019851385
-
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue
-
Matthew, W. D., Tsavaler, L. & Reichardt, L. F. Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. J. Cell Biol. 91, 257-269 (1981).
-
(1981)
J. Cell Biol.
, vol.91
, pp. 257-269
-
-
Matthew, W.D.1
Tsavaler, L.2
Reichardt, L.F.3
-
52
-
-
33845764296
-
A guided tour into subcellular colocalization analysis in light microscopy
-
Bolte, S. & Cordelieres, F. P. A guided tour into subcellular colocalization analysis in light microscopy. J. Microsc. Oxf. 224, 213-232 (2006).
-
(2006)
J. Microsc. Oxf.
, vol.224
, pp. 213-232
-
-
Bolte, S.1
Cordelieres, F.P.2
-
53
-
-
27344436659
-
Scalable molecular dynamics with NAMD
-
Phillips, J. C. et al. Scalable molecular dynamics with NAMD. J. Comput. Chem. 26, 1781-1802 (2005).
-
(2005)
J. Comput. Chem.
, vol.26
, pp. 1781-1802
-
-
Phillips, J.C.1
-
54
-
-
0041784950
-
All-atom empirical potential for molecular modeling and dynamics studies of proteins
-
MacKerell, A. D. et al. All-atom empirical potential for molecular modeling and dynamics studies of proteins. J. Phys. Chem. B 102, 3586-3616 (1998).
-
(1998)
J. Phys. Chem. B
, vol.102
, pp. 3586-3616
-
-
MacKerell, A.D.1
-
55
-
-
3142714765
-
Extending the treatment of backbone energetics in protein force fields: Limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations
-
Mackerell, A. D., Feig, M. & Brooks, C. L. Extending the treatment of backbone energetics in protein force fields: Limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations. J. Comput. Chem. 25, 1400-1415 (2004).
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1400-1415
-
-
Mackerell, A.D.1
Feig, M.2
Brooks, C.L.3
-
56
-
-
58149299971
-
Metadynamics: A method to simulate rare events and reconstruct the free energy in biophysics, chemistry and material science
-
Laio, A. & Gervasio, F. L. Metadynamics: a method to simulate rare events and reconstruct the free energy in biophysics, chemistry and material science. Rep. Prog. Phys. 71, 126601 (22pp) (2008).
-
(2008)
Rep. Prog. Phys.
, vol.71
, pp. 126601
-
-
Laio, A.1
Gervasio, F.L.2
-
57
-
-
0028670805
-
Cis-trans imide isomerization of the proline dipeptide
-
Fischer, S., Dunbrack, R. L. & Karplus, M. Cis-trans imide isomerization of the proline dipeptide. J. Am. Chem. Soc. 116, 11931-11937 (1994).
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 11931-11937
-
-
Fischer, S.1
Dunbrack, R.L.2
Karplus, M.3
-
58
-
-
67650500988
-
CHARMM: The biomolecular simulation program
-
Brooks, B. R. et al. CHARMM: the biomolecular simulation program. J. Comput. Chem. 30, 1545-1614 (2009).
-
(2009)
J. Comput. Chem.
, vol.30
, pp. 1545-1614
-
-
Brooks, B.R.1
-
59
-
-
34248584691
-
2+ sensors for fast release that specify distinct presynaptic properties in subsets of neurons
-
2+ sensors for fast release that specify distinct presynaptic properties in subsets of neurons. Neuron 54, 567-581 (2007).
-
(2007)
Neuron
, vol.54
, pp. 567-581
-
-
Xu, J.1
Mashimo, T.2
Sudhof, T.C.3
|