메뉴 건너뛰기




Volumn 86, Issue 12, 2016, Pages 1152-1158

Serotonin-to-dopamine transporter ratios in Parkinson disease

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 4 (2 DIMETHYLAMINOMETHYLPHENYL SULFANYL) BENZONITRILE C 11; DOPAMINE TRANSPORTER; LEVODOPA; N W FLUOROPROPYL 2BETA CARBOMETHOXY 3BETA (4 IODOPHENYL)NORTROPANE I 123; RADIOPHARMACEUTICAL AGENT; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

EID: 84961579281     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000002494     Document Type: Article
Times cited : (69)

References (34)
  • 1
    • 0036070538 scopus 로고    scopus 로고
    • L-DOPAinduced dyskinesia in the intrastriatal 6-hydroxydopamine model of Parkinson?s disease: Relation to motor and cellular parameters of nigrostriatal function
    • Winkler C, Kirik D, Björklund A, Cenci MA. L-DOPAinduced dyskinesia in the intrastriatal 6-hydroxydopamine model of Parkinson?s disease: relation to motor and cellular parameters of nigrostriatal function. Neurobiol Dis. 2002; 10: 165-186.
    • (2002) Neurobiol Dis , vol.10 , pp. 165-186
    • Winkler, C.1    Kirik, D.2    Björklund, A.3    Cenci, M.A.4
  • 2
    • 0029904201 scopus 로고    scopus 로고
    • Levodopa-induced changes in synaptic dopamine in patients with Parkinson?s disease as measured by [11C]raclopride displacement and PET
    • Tedroff J, Pedersen M, Aquilonius SM, Hartvig P, Jacobsson G, Långström B. Levodopa-induced changes in synaptic dopamine in patients with Parkinson?s disease as measured by [11C]raclopride displacement and PET. Neurology. 1996; 46: 1430-1436.
    • (1996) Neurology , vol.46 , pp. 1430-1436
    • Tedroff, J.1    Pedersen, M.2    Aquilonius, S.M.3    Hartvig, P.4    Jacobsson, G.5    Långström, B.6
  • 3
    • 10344236071 scopus 로고    scopus 로고
    • Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson?s disease: Implications for dyskinesias
    • de la Fuente-Fernández R, Sossi V, Huang Z, et al. Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson?s disease: implications for dyskinesias. Brain. 2004; 127: 2747-2754.
    • (2004) Brain , vol.127 , pp. 2747-2754
    • De La Fuente-Fernández, R.1    Sossi, V.2    Huang, Z.3
  • 4
    • 33750975077 scopus 로고    scopus 로고
    • Clinical correlates of levodopa-induced dopamine release in Parkinson disease: A PET study
    • Pavese N, Evans AH, Tai YF, et al. Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study. Neurology. 2006; 67: 1612-1617.
    • (2006) Neurology , vol.67 , pp. 1612-1617
    • Pavese, N.1    Evans, A.H.2    Tai, Y.F.3
  • 5
    • 0022551086 scopus 로고
    • Brain dopamine metabolism in patients with Parkinson?s disease measured with positron emission tomography
    • Leenders KL, Palmer AJ, Quinn N, et al. Brain dopamine metabolism in patients with Parkinson?s disease measured with positron emission tomography. J Neurol Neurosurg Psychiatry. 1986; 49: 853-860.
    • (1986) J Neurol Neurosurg Psychiatry , vol.49 , pp. 853-860
    • Leenders, K.L.1    Palmer, A.J.2    Quinn, N.3
  • 7
    • 0033601926 scopus 로고    scopus 로고
    • Role of serotonergic neurons in L-DOPAderived extracellular dopamine in the striatum of 6-OHDA-lesioned rats
    • Tanaka H, Kannari K, Maeda T, Tomiyama M, Suda T, Matsunaga M. Role of serotonergic neurons in L-DOPAderived extracellular dopamine in the striatum of 6-OHDA-lesioned rats. Neuroreport. 1999; 10: 631-634.
    • (1999) Neuroreport , vol.10 , pp. 631-634
    • Tanaka, H.1    Kannari, K.2    Maeda, T.3    Tomiyama, M.4    Suda, T.5    Matsunaga, M.6
  • 8
    • 20144378889 scopus 로고    scopus 로고
    • Serotonergic hyperinnervation into the dopaminergic denervated striatum compensates for dopamine conversion from exogenously administered l-DOPA
    • Maeda T, Nagata K, Yoshida Y, Kannari K. Serotonergic hyperinnervation into the dopaminergic denervated striatum compensates for dopamine conversion from exogenously administered l-DOPA. Brain Res. 2005; 1046: 230-233.
    • (2005) Brain Res , vol.1046 , pp. 230-233
    • Maeda, T.1    Nagata, K.2    Yoshida, Y.3    Kannari, K.4
  • 9
    • 33646822115 scopus 로고    scopus 로고
    • Reuptake of L-DOPA-derived extracellular dopamine in the striatum with dopaminergic denervation via serotonin transporters
    • Kannari K, Shen H, Arai A, Tomiyama M, Baba M. Reuptake of L-DOPA-derived extracellular dopamine in the striatum with dopaminergic denervation via serotonin transporters. Neurosci Lett. 2006; 402: 62-65.
    • (2006) Neurosci Lett , vol.402 , pp. 62-65
    • Kannari, K.1    Shen, H.2    Arai, A.3    Tomiyama, M.4    Baba, M.5
  • 10
    • 34447627504 scopus 로고    scopus 로고
    • Dopamine released from 5-HT terminals is the cause of L-DOPAinduced dyskinesia in parkinsonian rats
    • Carta M, Carlsson T, Kirik D, Björklund A. Dopamine released from 5-HT terminals is the cause of L-DOPAinduced dyskinesia in parkinsonian rats. Brain. 2007; 130: 1819-1833.
    • (2007) Brain , vol.130 , pp. 1819-1833
    • Carta, M.1    Carlsson, T.2    Kirik, D.3    Björklund, A.4
  • 11
    • 78249271694 scopus 로고    scopus 로고
    • Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia
    • Rylander D, Parent M, O?Sullivan SS, et al. Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia. Ann Neurol. 2010; 68: 619-628.
    • (2010) Ann Neurol , vol.68 , pp. 619-628
    • Rylander, D.1    Parent, M.2    Osullivan, S.S.3
  • 12
    • 84881556666 scopus 로고    scopus 로고
    • Study of the antidyskinetic effect of eltoprazine in animal models of levodopainduced dyskinesia
    • Bézard E, Tronci E, Pioli EY, et al. Study of the antidyskinetic effect of eltoprazine in animal models of levodopainduced dyskinesia. Mov Disord. 2013; 28: 1088-1096.
    • (2013) Mov Disord , vol.28 , pp. 1088-1096
    • Bézard, E.1    Tronci, E.2    Pioli, E.Y.3
  • 13
    • 84896751626 scopus 로고    scopus 로고
    • Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson?s disease patients
    • Politis M, Wu K, Loane C, et al. Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson?s disease patients. J Clin Invest. 2014; 124: 1340-1349.
    • (2014) J Clin Invest , vol.124 , pp. 1340-1349
    • Politis, M.1    Wu, K.2    Loane, C.3
  • 14
    • 0028936065 scopus 로고
    • The dopamine transporter: Immunochemical characterization and localization in brain
    • Ciliax BJ, Heilman C, Demchyshyn LL, et al. The dopamine transporter: immunochemical characterization and localization in brain. J Neurosci. 1995; 15: 1714-1723.
    • (1995) J Neurosci , vol.15 , pp. 1714-1723
    • Ciliax, B.J.1    Heilman, C.2    Demchyshyn, L.L.3
  • 15
    • 13844317450 scopus 로고    scopus 로고
    • Regional distribution of serotonin transporter protein in postmortem human brain: Is the cerebellum a SERT-free brain region?
    • Kish SJ, Furukawa Y, Chang LJ, et al. Regional distribution of serotonin transporter protein in postmortem human brain: is the cerebellum a SERT-free brain region?. Nucl Med Biol. 2005; 32: 123-128.
    • (2005) Nucl Med Biol , vol.32 , pp. 123-128
    • Kish, S.J.1    Furukawa, Y.2    Chang, L.J.3
  • 16
    • 0242382831 scopus 로고    scopus 로고
    • Dopamine transporter: Basic aspects and neuroimaging
    • Piccini P. Dopamine transporter: basic aspects and neuroimaging. Mov Disord. 2003; 18(suppl 7): S3-S8.
    • (2003) Mov Disord , vol.18 , pp. S3-S8
    • Piccini, P.1
  • 17
    • 77955844658 scopus 로고    scopus 로고
    • Staging of serotonergic dysfunction in Parkinson?s disease: An in vivo 11C-DASB PET study
    • Politis M, Wu K, Loane C, et al. Staging of serotonergic dysfunction in Parkinson?s disease: an in vivo 11C-DASB PET study. Neurobiol Dis. 2010; 40: 216-221.
    • (2010) Neurobiol Dis , vol.40 , pp. 216-221
    • Politis, M.1    Wu, K.2    Loane, C.3
  • 18
    • 0026629509 scopus 로고
    • What features improve the accuracy of clinical diagnosis in Parkinson?s disease: A clinicopathologic study
    • Hughes AJ, Ben-Shlomo Y, Daniel SE, Lees AJ. What features improve the accuracy of clinical diagnosis in Parkinson?s disease: a clinicopathologic study. Neurology. 1992; 42: 1142-1146.
    • (1992) Neurology , vol.42 , pp. 1142-1146
    • Hughes, A.J.1    Ben-Shlomo, Y.2    Daniel, S.E.3    Lees, A.J.4
  • 19
    • 0031279782 scopus 로고    scopus 로고
    • Parametric imaging of ligand-receptor binding in PET using a simplified reference region model
    • Gunn RN, Lammertsma AA, Hume SP, Cunningham VJ. Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage. 1997; 6: 279-287.
    • (1997) Neuroimage , vol.6 , pp. 279-287
    • Gunn, R.N.1    Lammertsma, A.A.2    Hume, S.P.3    Cunningham, V.J.4
  • 21
    • 0035200087 scopus 로고    scopus 로고
    • Positron emission tomography quantification of [(11)C]-DASB binding to the human serotonin transporter: Modeling strategies
    • Ginovart N, Wilson AA, Meyer JH, Hussey D, Houle S. Positron emission tomography quantification of [(11)C]-DASB binding to the human serotonin transporter: modeling strategies. J Cereb Blood Flow Metab. 2001; 21: 1342-1353.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1342-1353
    • Ginovart, N.1    Wilson, A.A.2    Meyer, J.H.3    Hussey, D.4    Houle, S.5
  • 22
    • 80052971467 scopus 로고    scopus 로고
    • Graft-induced dyskinesias in Parkinson?s disease: High striatal serotonin/dopamine transporter ratio
    • Politis M, Oertel WH, Wu K, et al. Graft-induced dyskinesias in Parkinson?s disease: high striatal serotonin/dopamine transporter ratio. Mov Disord. 2011; 26: 1997-2003.
    • (2011) Mov Disord , vol.26 , pp. 1997-2003
    • Politis, M.1    Oertel, W.H.2    Wu, K.3
  • 23
    • 0033491121 scopus 로고    scopus 로고
    • Dopamine release from nigral transplants visualized in vivo in a Parkinson?s patient
    • Piccini P, Brooks DJ, Björklund A, et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson?s patient. Nat Neurosci. 1999; 2: 1137-1140.
    • (1999) Nat Neurosci , vol.2 , pp. 1137-1140
    • Piccini, P.1    Brooks, D.J.2    Björklund, A.3
  • 24
    • 0035092779 scopus 로고    scopus 로고
    • Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson?s disease: PET evidence of increased dopamine turnover
    • de la Fuente-Fernández R, Lu JQ, Sossi V, et al. Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson?s disease: PET evidence of increased dopamine turnover. Ann Neurol. 2001; 49: 298-303.
    • (2001) Ann Neurol , vol.49 , pp. 298-303
    • De La Fuente-Fernández, R.1    Lu, J.Q.2    Sossi, V.3
  • 25
    • 33645055382 scopus 로고    scopus 로고
    • Age-related differences in levodopa dynamics in Parkinson?s: Implications for motor complications
    • Sossi V, de la Fuente-Fernández R, Schulzer M, Adams J, Stoessl J. Age-related differences in levodopa dynamics in Parkinson?s: implications for motor complications. Brain. 2006; 129: 1050-1058.
    • (2006) Brain , vol.129 , pp. 1050-1058
    • Sossi, V.1    De La Fuente-Fernández, R.2    Schulzer, M.3    Adams, J.4    Stoessl, J.5
  • 26
    • 84891960316 scopus 로고    scopus 로고
    • Serotonergic nerve fibers in L-DOPA-derived dopamine release and dyskinesia
    • Nevalainen N, Af Bjerkén S, Gerhardt GA, Strömberg I. Serotonergic nerve fibers in L-DOPA-derived dopamine release and dyskinesia. Neuroscience. 2014; 260: 73-86.
    • (2014) Neuroscience , vol.260 , pp. 73-86
    • Nevalainen, N.1    Af Bjerkén, S.2    Gerhardt, G.A.3    Strömberg, I.4
  • 27
    • 84885415685 scopus 로고    scopus 로고
    • Effects of prolonged selective serotonin reuptake inhibition on the development and expression of L-DOPA-induced dyskinesia in hemi-parkinsonian rats
    • Conti MM, Ostock CY, Lindenbach D, et al. Effects of prolonged selective serotonin reuptake inhibition on the development and expression of L-DOPA-induced dyskinesia in hemi-parkinsonian rats. Neuropharmacology. 2014; 77: 1-8.
    • (2014) Neuropharmacology , vol.77 , pp. 1-8
    • Conti, M.M.1    Ostock, C.Y.2    Lindenbach, D.3
  • 28
    • 58149107401 scopus 로고    scopus 로고
    • Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPAinduced dyskinesia
    • Muñoz A, Li Q, Gardoni F, et al. Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPAinduced dyskinesia. Brain. 2008; 131: 3380-3394.
    • (2008) Brain , vol.131 , pp. 3380-3394
    • Muñoz, A.1    Li, Q.2    Gardoni, F.3
  • 29
    • 84929094487 scopus 로고    scopus 로고
    • Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson?s disease: A dose-finding study
    • Svenningsson P, Rosenblad C, Af Edholm Arvidsson K, et al. Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson?s disease: a dose-finding study. Brain. 2015; 138: 963-973.
    • (2015) Brain , vol.138 , pp. 963-973
    • Svenningsson, P.1    Rosenblad, C.2    Af Edholm Arvidsson, K.3
  • 31
    • 0033390640 scopus 로고    scopus 로고
    • Risk factors for levodopa-induced dyskinesias in Parkinson?s disease
    • Grandas F, Galiano ML, Tabernero C. Risk factors for levodopa-induced dyskinesias in Parkinson?s disease. J Neurol. 1999; 246: 1127-1133.
    • (1999) J Neurol , vol.246 , pp. 1127-1133
    • Grandas, F.1    Galiano, M.L.2    Tabernero, C.3
  • 32
    • 79953278055 scopus 로고    scopus 로고
    • The motor phenotype of Parkinson?s disease in relation to age at onset
    • Wickremaratchi MM, Knipe MD, Sastry BS, et al. The motor phenotype of Parkinson?s disease in relation to age at onset. Mov Disord. 2011; 26: 457-463.
    • (2011) Mov Disord , vol.26 , pp. 457-463
    • Wickremaratchi, M.M.1    Knipe, M.D.2    Sastry, B.S.3
  • 33
    • 84881558752 scopus 로고    scopus 로고
    • Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson?s disease
    • Olanow WC, Kieburtz K, Rascol O, et al. Factors predictive of the development of Levodopa-induced dyskinesia and wearing-off in Parkinson?s disease. Mov Disord. 2013; 28: 1064-1071.
    • (2013) Mov Disord , vol.28 , pp. 1064-1071
    • Olanow, W.C.1    Kieburtz, K.2    Rascol, O.3
  • 34
    • 0033768218 scopus 로고    scopus 로고
    • Dyskinesias and motor fluctuations in Parkinson?s disease: A community-based study
    • Schrag A, Quinn N. Dyskinesias and motor fluctuations in Parkinson?s disease: a community-based study. Brain. 2000; 123: 2297-2305.
    • (2000) Brain , vol.123 , pp. 2297-2305
    • Schrag, A.1    Quinn, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.