-
1
-
-
0025572253
-
6-[18F]fluoro-L-dopa probes dopamine turnover rates in central dopaminergic structures
-
Barrio JR, Huang SC, Melega WP, Yu DC, Hoffman JM, Schneider JS, et al. 6-[18F]fluoro-L-dopa probes dopamine turnover rates in central dopaminergic structures. J Neurosci Res 1990; 27: 487-93.
-
(1990)
J Neurosci Res
, vol.27
, pp. 487-493
-
-
Barrio, J.R.1
Huang, S.C.2
Melega, W.P.3
Yu, D.C.4
Hoffman, J.M.5
Schneider, J.S.6
-
2
-
-
0028031450
-
Age dependent decline of nigrostriatal dopaminergic function: A positron emission tomographic study of grandparents and their grandchildren
-
Cordes M, Snow BJ, Cooper S, Schulzer M, Pate BD, Ruth TJ, et al. Age dependent decline of nigrostriatal dopaminergic function: a positron emission tomographic study of grandparents and their grandchildren. Ann Neurol 1994; 36: 667-70.
-
(1994)
Ann Neurol
, vol.36
, pp. 667-670
-
-
Cordes, M.1
Snow, B.J.2
Cooper, S.3
Schulzer, M.4
Pate, B.D.5
Ruth, T.J.6
-
3
-
-
0033955756
-
Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations
-
de la Fuente-Fernández R, Pal PK, Vingerhoets FJG, Kishore A, Schulzer M, Mak EK, et al. Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations. J Neural Transm 2000; 107: 49-57.
-
(2000)
J Neural Transm
, vol.107
, pp. 49-57
-
-
De La Fuente-Fernández, R.1
Pal, P.K.2
Vingerhoets, F.J.G.3
Kishore, A.4
Schulzer, M.5
Mak, E.K.6
-
4
-
-
0035092779
-
Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover
-
de la Fuente-Fernández R, Lu J-Q, Sossi V, Jivan S, Schulzer M, Holden JE, et al. Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover. Ann Neurol 2001; 49: 298-303.
-
(2001)
Ann Neurol
, vol.49
, pp. 298-303
-
-
De La Fuente-Fernández, R.1
Lu, J.-Q.2
Sossi, V.3
Jivan, S.4
Schulzer, M.5
Holden, J.E.6
-
5
-
-
0037290966
-
Age and severity of nigrostriatal damage at onset of Parkinson's disease
-
de la Fuente-Fernandez R, Lim AS, Sossi V, Adam MJ, Ruth TJ, Calne DB, et al. Age and severity of nigrostriatal damage at onset of Parkinson's disease. Synapse 2003; 47: 152-8.
-
(2003)
Synapse
, vol.47
, pp. 152-158
-
-
De La Fuente-Fernandez, R.1
Lim, A.S.2
Sossi, V.3
Adam, M.J.4
Ruth, T.J.5
Calne, D.B.6
-
6
-
-
18344402736
-
Presynaptic mechanisms of motor fluctuations in Parkinson's disease: A probabilistic model
-
de la Fuente-Fernández R, Schulzer M, Mak E, Calne DB, Stoessl A. Presynaptic mechanisms of motor fluctuations in Parkinson's disease: a probabilistic model. Brain 2004a; 127: 888-99.
-
(2004)
Brain
, vol.127
, pp. 888-899
-
-
De La Fuente-Fernández, R.1
Schulzer, M.2
Mak, E.3
Calne, D.B.4
Stoessl, A.5
-
7
-
-
10344236071
-
Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: Implications for dyskinesias
-
de la Fuente-Fernandez R, Sossi V, Huang Z, Furtado S, Lu JQ, Calne DB, et al. Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias. Brain 2004b; 127: 2747-54.
-
(2004)
Brain
, vol.127
, pp. 2747-2754
-
-
De La Fuente-Fernandez, R.1
Sossi, V.2
Huang, Z.3
Furtado, S.4
Lu, J.Q.5
Calne, D.B.6
-
9
-
-
0027337149
-
Striatal 18F-dopa uptake: Absence of an aging effect
-
Eidelberg D, Takikawa S, Dhawan V, Chaly T, Robeson W, Dahl R, et al. Striatal 18F-dopa uptake: absence of an aging effect. J Cereb Blood Flow Metab 1993; 13: 881-8.
-
(1993)
J Cereb Blood Flow Metab
, vol.13
, pp. 881-888
-
-
Eidelberg, D.1
Takikawa, S.2
Dhawan, V.3
Chaly, T.4
Robeson, W.5
Dahl, R.6
-
10
-
-
0025954066
-
Ageing and Parkinson's disease: Substantia nigra regional selectivity
-
Fearnley JM, Lees AJ. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 1991; 114: 2283-301.
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.M.1
Lees, A.J.2
-
11
-
-
0030768730
-
Age-related increases in brain monoamine oxidase B in living healthy human subjects
-
Fowler JS, Volkow ND, Wang GJ, Logan J, Pappas N, Shea C, et al. Age-related increases in brain monoamine oxidase B in living healthy human subjects. Neurobiol Aging 1997; 18: 431-5.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 431-435
-
-
Fowler, J.S.1
Volkow, N.D.2
Wang, G.J.3
Logan, J.4
Pappas, N.5
Shea, C.6
-
12
-
-
0030511826
-
Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging
-
Frey KA, Koeppe RA, Kilbourn MR, Vander Borght TM, Albin RL, Gilman S, et al. Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging. Ann Neurol 1996; 40: 873-84.
-
(1996)
Ann Neurol
, vol.40
, pp. 873-884
-
-
Frey, K.A.1
Koeppe, R.A.2
Kilbourn, M.R.3
Vander Borght, T.M.4
Albin, R.L.5
Gilman, S.6
-
13
-
-
0019794669
-
High- and low-affinity transport of D-glucose from blood to brain
-
Gjedde A. High- and low-affinity transport of D-glucose from blood to brain. J Neurochem 1981; 36: 1436-71.
-
(1981)
J Neurochem
, vol.36
, pp. 1436-1471
-
-
Gjedde, A.1
-
14
-
-
0020321344
-
Calculation of glucose phoshorylation from brain uptake of glucose analogues in vivo: A re-examination
-
Gjedde A. Calculation of glucose phoshorylation from brain uptake of glucose analogues in vivo: a re-examination. Brain Res 1982; 357: 237-74.
-
(1982)
Brain Res
, vol.357
, pp. 237-274
-
-
Gjedde, A.1
-
15
-
-
0001293660
-
The aging neuron - Influence on symptomatology and therapeutic response in Parkinson's syndrome
-
Poirier LJ, Sourkes TL, Bedard PJ, editors. New York: Raven Press
-
Granérus AK, Carlsson A, Svanborg A. The aging neuron - influence on symptomatology and therapeutic response in Parkinson's syndrome. In: Poirier LJ, Sourkes TL, Bedard PJ, editors. Advances in neurology. Vol. 24, New York: Raven Press; 1979. p. 327-35.
-
(1979)
Advances in Neurology
, vol.24
, pp. 327-335
-
-
Granérus, A.K.1
Carlsson, A.2
Svanborg, A.3
-
16
-
-
0142179249
-
Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum
-
Haycock JW, Becker L, Ang L, Furukawa Y, Hornykiewicz O, Kish SJ. Marked disparity between age-related changes in dopamine and other presynaptic dopaminergic markers in human striatum. J Neurochem 2003; 87: 574-85.
-
(2003)
J Neurochem
, vol.87
, pp. 574-585
-
-
Haycock, J.W.1
Becker, L.2
Ang, L.3
Furukawa, Y.4
Hornykiewicz, O.5
Kish, S.J.6
-
17
-
-
0003096328
-
Brain neurotransmitter changes in Parkinson's disease
-
Marsden CD, Fahn S, editors. London: Butterworth
-
Hornykiewicz O. Brain neurotransmitter changes in Parkinson's disease. In: Marsden CD, Fahn S, editors. Movement disorders. London: Butterworth; 1982. p. 41-58.
-
(1982)
Movement Disorders
, pp. 41-58
-
-
Hornykiewicz, O.1
-
18
-
-
0026569594
-
Aging produces a specific pattern of striatal dopamine loss: Implications for the etiology of idiopathic Parkinson's disease
-
Kish SJ, Shannak K, Rajput A, Deck JHN, Hornykiewicz O. Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease. J Neurochem 1992; 58: 642-8.
-
(1992)
J Neurochem
, vol.58
, pp. 642-648
-
-
Kish, S.J.1
Shannak, K.2
Rajput, A.3
Deck, J.H.N.4
Hornykiewicz, O.5
-
20
-
-
84938465236
-
Early development of levodopa-induced dyskinesias and response fluctuations in young-onset Parkinson's disease
-
Kostic V, Przedborski S, Flaster E, Sternic N. Early development of levodopa-induced dyskinesias and response fluctuations in young-onset Parkinson's disease. Neurology 1991; 41: 202-5.
-
(1991)
Neurology
, vol.41
, pp. 202-205
-
-
Kostic, V.1
Przedborski, S.2
Flaster, E.3
Sternic, N.4
-
21
-
-
21344464929
-
PET studies of net blood-brain clearance of FDOPA to human brain: Age-dependent decline of [18F]fluorodopamine storage capacity
-
Kumakura Y, Vernaleken I, Grunder G, Bartenstein P, Gjedde A, Cumming P. PET studies of net blood-brain clearance of FDOPA to human brain: age-dependent decline of [18F]fluorodopamine storage capacity. J Cereb Blood Flow Metab 2005; 25: 807-19.
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, pp. 807-819
-
-
Kumakura, Y.1
Vernaleken, I.2
Grunder, G.3
Bartenstein, P.4
Gjedde, A.5
Cumming, P.6
-
22
-
-
4644285991
-
Perspectives on MAO-B in aging and neurological disease: Where do we go from here?
-
Kumar MJ, Andersen JK. Perspectives on MAO-B in aging and neurological disease: where do we go from here? Mol Neurobiol 2004; 30: 77-89.
-
(2004)
Mol Neurobiol
, vol.30
, pp. 77-89
-
-
Kumar, M.J.1
Andersen, J.K.2
-
23
-
-
0004517004
-
Dopamine turnover is increased in striatum of patients with Parkinson's disease
-
Sendai Japan, May 22-28
-
Kuwabara H, Cumming P, Yasuhara Y, Leger GC, Guttman M, Diksic M, et al. Dopamine turnover is increased in striatum of patients with Parkinson's disease. Brain 1993; Sendai Japan, May 22-28.
-
(1993)
Brain
-
-
Kuwabara, H.1
Cumming, P.2
Yasuhara, Y.3
Leger, G.C.4
Guttman, M.5
Diksic, M.6
-
24
-
-
18844471416
-
In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease
-
Lee CS, Samii A, Sossi V, Ruth TJ, Schulzer M, Holden JE, et al. In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann Neurol 2000; 47: 493-503.
-
(2000)
Ann Neurol
, vol.47
, pp. 493-503
-
-
Lee, C.S.1
Samii, A.2
Sossi, V.3
Ruth, T.J.4
Schulzer, M.5
Holden, J.E.6
-
25
-
-
10044247418
-
Lack of regional selectivity during the progression of Parkinson disease: Implications for pathogenesis
-
Lee CS, Schulzer M, de la Fuente-Fernandez R, Mak E, Kuramoto L, Sossi V, et al. Lack of regional selectivity during the progression of Parkinson disease: implications for pathogenesis. Arch Neurol 2004; 61: 1920-5.
-
(2004)
Arch Neurol
, vol.61
, pp. 1920-1925
-
-
Lee, C.S.1
Schulzer, M.2
De La Fuente-Fernandez, R.3
Mak, E.4
Kuramoto, L.5
Sossi, V.6
-
26
-
-
0001925175
-
Fluctuations of disability in Parkinson's disease - Clinical aspects
-
Marsden CD, Fahn S, editors. London: Butterworth
-
Marsden CD, Parkes JD, Quinn N. Fluctuations of disability in Parkinson's disease - clinical aspects. In: Marsden CD, Fahn S, editors. Movement disorders. London: Butterworth; 1982. p. 96-122.
-
(1982)
Movement Disorders
, pp. 96-122
-
-
Marsden, C.D.1
Parkes, J.D.2
Quinn, N.3
-
27
-
-
0017275668
-
On-off effects in patients with Parkinsons disease on chronic levodopa therapy
-
Marsden CD, Parkes JD. On-off effects in patients with Parkinsons disease on chronic levodopa therapy. Lancet 1976; 1: 292-6.
-
(1976)
Lancet
, vol.1
, pp. 292-296
-
-
Marsden, C.D.1
Parkes, J.D.2
-
28
-
-
0024457531
-
Nigrostriatal function in man studied with positron emission tomography
-
Martin WRW, Palmer MR, Patlak CS, Calne DB. Nigrostriatal function in man studied with positron emission tomography. Ann Neurol 1989; 26: 535-42.
-
(1989)
Ann Neurol
, vol.26
, pp. 535-542
-
-
Martin, W.R.W.1
Palmer, M.R.2
Patlak, C.S.3
Calne, D.B.4
-
31
-
-
0034642339
-
The evolution and origin of motor complications in Parkinson's disease
-
Obeso JA, Rodrigues-Oroz MC, Chana P, Lera G, Rodriguez M, Olanow CW. The evolution and origin of motor complications in Parkinson's disease. Neurology 2000; 55: S13-20.
-
(2000)
Neurology
, vol.55
-
-
Obeso, J.A.1
Rodrigues-Oroz, M.C.2
Chana, P.3
Lera, G.4
Rodriguez, M.5
Olanow, C.W.6
-
32
-
-
0020956774
-
Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data
-
Patlak CS, Blasberg RG, Fenstermacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983; 3: 1-7.
-
(1983)
J Cereb Blood Flow Metab
, vol.3
, pp. 1-7
-
-
Patlak, C.S.1
Blasberg, R.G.2
Fenstermacher, J.D.3
-
33
-
-
0025610738
-
Striatal function in normal aging: Implications for Parkinson's disease
-
Sawle GV, Colebatch JG, Shah A, Brooks DJ, Marsden CD, Frackowiak RS. Striatal function in normal aging: implications for Parkinson's disease. Ann Neurol 1990; 28: 799-804.
-
(1990)
Ann Neurol
, vol.28
, pp. 799-804
-
-
Sawle, G.V.1
Colebatch, J.G.2
Shah, A.3
Brooks, D.J.4
Marsden, C.D.5
Frackowiak, R.S.6
-
34
-
-
0031665076
-
Quantitative comparison of three- and two-dimensional PET with human brain studies
-
Sossi V, Oakes TR, Chan GL, Schulzer M, Ruth TJ. Quantitative comparison of three- and two-dimensional PET with human brain studies. J Nucl Med 1998; 39: 1714-9.
-
(1998)
J Nucl Med
, vol.39
, pp. 1714-1719
-
-
Sossi, V.1
Oakes, T.R.2
Chan, G.L.3
Schulzer, M.4
Ruth, T.J.5
-
35
-
-
0035053443
-
A reversible tracer analysis approach to the study of effective dopamine turnover
-
Sossi V, Doudet DJ, Holden JE. A reversible tracer analysis approach to the study of effective dopamine turnover. J Cereb Blood Flow Metab 2001; 21: 469-76.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 469-476
-
-
Sossi, V.1
Doudet, D.J.2
Holden, J.E.3
-
36
-
-
0036167679
-
Increase in dopamine turnover occurs early in Parkinson's disease: Evidence from a new modeling approach to PET 18F-fluorodopa data
-
Sossi V, de la Fuente-Fernãndez R, Holden JE, Doudet DJ, McKenzie J, Stoessl AJ, et al. Increase in dopamine turnover occurs early in Parkinson's disease: evidence from a new modeling approach to PET 18F-fluorodopa data. J Cereb Blood Flow and Metab 2002; 22: 232-39.
-
(2002)
J Cereb Blood Flow and Metab
, vol.22
, pp. 232-239
-
-
Sossi, V.1
De La Fuente-Fernãndez, R.2
Holden, J.E.3
Doudet, D.J.4
McKenzie, J.5
Stoessl, A.J.6
-
38
-
-
3843057052
-
Changes of dopamine turnover in the progression of Parkinson's disease as measured by positron emission tomography: Their relation to disease-compensatory mechanisms
-
Sossi V, de la Fuente-Fernandez R, Holden JE, Schulzer M, Ruth TJ, Stoessl J. Changes of dopamine turnover in the progression of Parkinson's disease as measured by positron emission tomography: their relation to disease-compensatory mechanisms. J Cereb Blood Flow Metab 2004; 24: 869-76.
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, pp. 869-876
-
-
Sossi, V.1
De La Fuente-Fernandez, R.2
Holden, J.E.3
Schulzer, M.4
Ruth, T.J.5
Stoessl, J.6
-
39
-
-
85039793961
-
18F-fluorodopa uptake rate and dopamine turnover PET markers and implications for Parkinson's disease progression
-
June 7-11, Amsterdam, The Netherlands, CDROM
-
18F-fluorodopa uptake rate and dopamine turnover PET markers and implications for Parkinson's disease progression. In: Proceedings of the XXIInd International Symposium on Cerebral Blood Flow, Metabolism, and Function, June 7-11, 2005, Amsterdam, The Netherlands, CDROM.
-
(2005)
Proceedings of the XXIInd International Symposium on Cerebral Blood Flow, Metabolism, and Function
-
-
Sossi, V.1
Holden, J.E.2
Schulzer, M.3
Ruth, T.J.4
Stoessl, A.J.5
-
40
-
-
0026710516
-
Physical performance of a positron tomograph for brain imaging with retractable septa
-
Spinks TJ, Jones T, Bailey DJ, Townsend DW, Grootoonk S, Bloomfield PM, et al. Physical performance of a positron tomograph for brain imaging with retractable septa. Phys Med Biol 1992; 37: 1637-55.
-
(1992)
Phys Med Biol
, vol.37
, pp. 1637-1655
-
-
Spinks, T.J.1
Jones, T.2
Bailey, D.J.3
Townsend, D.W.4
Grootoonk, S.5
Bloomfield, P.M.6
-
41
-
-
20844454214
-
Intermittent vs continuous levodopa administration in patients with advanced Parkinson disease: A clinical and pharmacokinetic study
-
Stocchi F, Vacca L, Ruggieri S, Olanow CW. Intermittent vs continuous levodopa administration in patients with advanced Parkinson disease: a clinical and pharmacokinetic study. Arch Neurol 2005; 62: 905-10.
-
(2005)
Arch Neurol
, vol.62
, pp. 905-910
-
-
Stocchi, F.1
Vacca, L.2
Ruggieri, S.3
Olanow, C.W.4
|