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Volumn 14, Issue 3, 2016, Pages 186-193

Role of the androgen receptor in triple-negative breast cancer

Author keywords

Androgen receptor; AR; Bicalutamide; Enzalutamide; TNBC; Triple negative breast cancer

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; ANTHRACYCLINE; ANTIANDROGEN; BICALUTAMIDE; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; ENZALUTAMIDE; ORTERONEL; RIBOCICLIB; TASELISIB; TESTOSTERONE; ANDROGEN RECEPTOR ANTAGONIST; ANTINEOPLASTIC AGENT;

EID: 84961575305     PISSN: 15430790     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (110)

References (88)
  • 1
    • 84918815964 scopus 로고    scopus 로고
    • Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
    • Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136(5):E359-E386.
    • (2015) Int J Cancer , vol.136 , Issue.5 , pp. E359-E386
    • Ferlay, J.1    Soerjomataram, I.2    Dikshit, R.3
  • 2
    • 17644421000 scopus 로고    scopus 로고
    • 1975-2009 (Vintage 2009 Populations). National Cancer Institute Updated April 2012. Accessed January 29, 2016
    • Howlader N, Noone AM, Krapcho M, et al (eds). SEER Cancer Statistics Review, 1975-2009 (Vintage 2009 Populations). National Cancer Institute. http://seer.can­cer.gov/csr/1975_2009_pops09/. Updated April 2012. Accessed January 29, 2016.
    • SEER Cancer Statistics Review
    • Howlader, N.1    Noone, A.M.2    Krapcho, M.3
  • 3
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society
    • American Cancer Society. Cancer Facts & Figures 2015. http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2015/index. Accessed January 29, 2015.
    • Cancer Facts & Figures 2015
  • 4
    • 79959503213 scopus 로고    scopus 로고
    • Triple-negative breast cancer: An unmet medical need
    • Hudis CA, Gianni L. Triple-negative breast cancer: an unmet medical need. Oncologist. 2011;16(1):1-11.
    • (2011) Oncologist , vol.16 , Issue.1 , pp. 1-11
    • Hudis, C.A.1    Gianni, L.2
  • 5
    • 84867123853 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Epidemiological considerations and rec­ommendations
    • Boyle P. Triple-negative breast cancer: epidemiological considerations and rec­ommendations. Ann Oncol. 2012;23(6):vi7-vi12.
    • (2012) Ann Oncol. , vol.23 , Issue.6
    • Boyle, P.1
  • 6
    • 34247569300 scopus 로고    scopus 로고
    • Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: A population-based study from the California cancer Registry
    • Bauer KR, Brown M, Cress RD, Parise CA, Caggiano V. Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California cancer Registry. Cancer. 2007;109(9):1721-1728.
    • (2007) Cancer , vol.109 , Issue.9 , pp. 1721-1728
    • Bauer, K.R.1    Brown, M.2    Cress, R.D.3    Parise, C.A.4    Caggiano, V.5
  • 7
    • 33744960226 scopus 로고    scopus 로고
    • Race, breast cancer subtypes, and sur­vival in the Carolina Breast Cancer Study
    • Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and sur­vival in the Carolina Breast Cancer Study. JAMA. 2006;295(21):2492-2502.
    • (2006) JAMA , vol.295 , Issue.21 , pp. 2492-2502
    • Carey, L.A.1    Perou, C.M.2    Livasy, C.A.3
  • 8
    • 80051518997 scopus 로고    scopus 로고
    • Triple-negative breast cancer in Hispanic patients: High prevalence, poor prognosis, and association with menopausal status, body mass index, and parity
    • Lara-Medina F, Pérez-Sánchez V, Saavedra-Pérez D, et al. Triple-negative breast cancer in Hispanic patients: high prevalence, poor prognosis, and association with menopausal status, body mass index, and parity. Cancer. 2011;117(16):3658-3669.
    • (2011) Cancer , vol.117 , Issue.16 , pp. 3658-3669
    • Lara-Medina, F.1    Pérez-Sánchez, V.2    Saavedra-Pérez, D.3
  • 9
    • 84865573852 scopus 로고    scopus 로고
    • Targeting triple-negative breast cancer: Optimising therapeutic outcomes
    • Gelmon K, Dent R, Mackey JR, Laing K, McLeod D, Verma S. Targeting triple-negative breast cancer: optimising therapeutic outcomes. Ann Oncol. 2012;23(9):2223-2234.
    • (2012) Ann Oncol , vol.23 , Issue.9 , pp. 2223-2234
    • Gelmon, K.1    Dent, R.2    Mackey, J.R.3    Laing, K.4    McLeod, D.5    Verma, S.6
  • 10
    • 65649151690 scopus 로고    scopus 로고
    • Survival outcomes for patients with metastatic triple-negative breast cancer: Implications for clinical practice and trial design
    • Kassam F, Enright K, Dent R, et al. Survival outcomes for patients with metastatic triple-negative breast cancer: implications for clinical practice and trial design. Clin Breast Cancer. 2009;9(1):29-33.
    • (2009) Clin Breast Cancer , vol.9 , Issue.1 , pp. 29-33
    • Kassam, F.1    Enright, K.2    Dent, R.3
  • 11
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sørlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406(6797):747-752.
    • (2000) Nature , vol.406 , Issue.6797 , pp. 747-752
    • Perou, C.M.1    Sørlie, T.2    Eisen, M.B.3
  • 12
    • 30944450821 scopus 로고    scopus 로고
    • Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
    • Livasy CA, Karaca G, Nanda R, et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol. 2006;19(2):264-271.
    • (2006) Mod Pathol , vol.19 , Issue.2 , pp. 264-271
    • Livasy, C.A.1    Karaca, G.2    Nanda, R.3
  • 13
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A. 2003;100(14):8418-8423.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.14 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3
  • 14
    • 4143150688 scopus 로고    scopus 로고
    • Immunohistochemical and clinical char­acterization of the basal-like subtype of invasive breast carcinoma
    • Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical char­acterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004;10(16):5367-5374.
    • (2004) Clin Cancer Res , vol.10 , Issue.16 , pp. 5367-5374
    • Nielsen, T.O.1    Hsu, F.D.2    Jensen, K.3
  • 15
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • Lehmann BD, Bauer JA, Chen X, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest. 2011;121(7):2750-2767.
    • (2011) J Clin Invest , vol.121 , Issue.7 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3
  • 16
    • 84886412350 scopus 로고    scopus 로고
    • Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes
    • Masuda H, Baggerly KA, Wang Y, et al. Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes. Clin Cancer Res. 2013;19(19):5533-5540.
    • (2013) Clin Cancer Res , vol.19 , Issue.19 , pp. 5533-5540
    • Masuda, H.1    Baggerly, K.A.2    Wang, Y.3
  • 17
    • 84926642123 scopus 로고    scopus 로고
    • Gene-expression molecular subtyping of triple-negative breast cancer tumours: Importance of immune response
    • Jézéquel P, Loussouarn D, Guérin-Charbonnel C, et al. Gene-expression molecular subtyping of triple-negative breast cancer tumours: importance of immune response. Breast Cancer Res. 2015;17:43.
    • (2015) Breast Cancer Res , vol.17
    • Jézéquel, P.1    Loussouarn, D.2    Guérin-Charbonnel, C.3
  • 18
    • 84878069977 scopus 로고    scopus 로고
    • Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer
    • Yu KD, Zhu R, Zhan M, et al. Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer. Clin Cancer Res. 2013;19(10):2723-2733.
    • (2013) Clin Cancer Res , vol.19 , Issue.10 , pp. 2723-2733
    • Yu, K.D.1    Zhu, R.2    Zhan, M.3
  • 19
    • 84931066891 scopus 로고    scopus 로고
    • Multiple molecular subtypes of triple-negative breast cancer critically rely on androgen receptor and respond to enzalutamide in vivo
    • Barton VN, D’Amato NC, Gordon MA, et al. Multiple molecular subtypes of triple-negative breast cancer critically rely on androgen receptor and respond to enzalutamide in vivo. Mol Cancer Ther. 2015;14(3):769-778.
    • (2015) Mol Cancer Ther , vol.14 , Issue.3 , pp. 769-778
    • Barton, V.N.1    D’Amato, N.C.2    Gordon, M.A.3
  • 20
    • 34547760403 scopus 로고    scopus 로고
    • Disruption of androgen receptor signaling by synthetic progestins may increase risk of develop­ing breast cancer
    • Birrell SN, Butler LM, Harris JM, Buchanan G, Tilley WD. Disruption of androgen receptor signaling by synthetic progestins may increase risk of develop­ing breast cancer. FASEB J. 2007;21(10):2285-2293.
    • (2007) FASEB J , vol.21 , Issue.10 , pp. 2285-2293
    • Birrell, S.N.1    Butler, L.M.2    Harris, J.M.3    Buchanan, G.4    Tilley, W.D.5
  • 21
    • 0019412023 scopus 로고
    • Role of gonadal hormones in development of the sexual phenotypes
    • Wilson JD, Griffin JE, Leshin M, George FW. Role of gonadal hormones in development of the sexual phenotypes. Hum Genet. 1981;58(1):78-84.
    • (1981) Hum Genet , vol.58 , Issue.1 , pp. 78-84
    • Wilson, J.D.1    Griffin, J.E.2    Leshin, M.3    George, F.W.4
  • 22
    • 0033603590 scopus 로고    scopus 로고
    • Androgen stimulates mitogen-activated protein kinase in human breast cancer cells
    • Zhu X, Li H, Liu JP, Funder JW. Androgen stimulates mitogen-activated protein kinase in human breast cancer cells. Mol Cell Endocrinol. 1999;152(1-2):199-206.
    • (1999) Mol Cell Endocrinol , vol.152 , Issue.1-2 , pp. 199-206
    • Zhu, X.1    Li, H.2    Liu, J.P.3    Funder, J.W.4
  • 23
    • 68049128114 scopus 로고    scopus 로고
    • Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer
    • Peters AA, Buchanan G, Ricciardelli C, et al. Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer. Cancer Res. 2009;69(15):6131-6140.
    • (2009) Cancer Res , vol.69 , Issue.15 , pp. 6131-6140
    • Peters, A.A.1    Buchanan, G.2    Ricciardelli, C.3
  • 24
    • 0035237423 scopus 로고    scopus 로고
    • The role of androgens in mammary carcinogenesis
    • Wong YC, Xie B. The role of androgens in mammary carcinogenesis. Ital J Anat Embryol. 2001;106(2)(1):111-125.
    • (2001) Ital J Anat Embryol , vol.106 , Issue.1-2 , pp. 111-125
    • Wong, Y.C.1    Xie, B.2
  • 25
    • 33749538836 scopus 로고    scopus 로고
    • Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women
    • Eliassen AH, Missmer SA, Tworoger SS, et al. Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women. J Natl Cancer Inst. 2006;98(19):1406-1415.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.19 , pp. 1406-1415
    • Eliassen, A.H.1    Missmer, S.A.2    Tworoger, S.S.3
  • 26
  • 27
    • 84911458339 scopus 로고    scopus 로고
    • Androgen receptor (AR) expression in 400 breast carcinomas: Is routine AR assessment justified?
    • Safarpour D, Pakneshan S, Tavassoli FA. Androgen receptor (AR) expression in 400 breast carcinomas: is routine AR assessment justified? Am J Cancer Res. 2014;4(4):353-368.
    • (2014) Am J Cancer Res , vol.4 , Issue.4 , pp. 353-368
    • Safarpour, D.1    Pakneshan, S.2    Tavassoli, F.A.3
  • 28
    • 54849414696 scopus 로고    scopus 로고
    • Androgen receptor expression in breast cancer: Relationship with clinicopathological factors and biomarkers
    • Ogawa Y, Hai E, Matsumoto K, et al. Androgen receptor expression in breast cancer: relationship with clinicopathological factors and biomarkers. Int J Clin Oncol. 2008;13(5):431-435.
    • (2008) Int J Clin Oncol , vol.13 , Issue.5 , pp. 431-435
    • Ogawa, Y.1    Hai, E.2    Matsumoto, K.3
  • 29
    • 77649188673 scopus 로고    scopus 로고
    • Expression of androgen receptors in primary breast cancer
    • Park S, Koo J, Park HS, et al. Expression of androgen receptors in primary breast cancer. Ann Oncol. 2010;21(3):488-492.
    • (2010) Ann Oncol , vol.21 , Issue.3 , pp. 488-492
    • Park, S.1    Koo, J.2    Park, H.S.3
  • 30
    • 33748448911 scopus 로고    scopus 로고
    • The clinical significance of androgen receptors in breast cancer and their relation to histological and cell biological parameters
    • Kuenen-Boumeester V, Van der Kwast TH, Claassen CC, et al. The clinical significance of androgen receptors in breast cancer and their relation to histological and cell biological parameters. Eur J Cancer. 1996;32A(9):1560-1565.
    • (1996) Eur J Cancer , vol.32B , Issue.9 , pp. 1560-1565
    • Kuenen-Boumeester, V.1    Van Der Kwast, T.H.2    Claassen, C.C.3
  • 31
    • 0042071592 scopus 로고    scopus 로고
    • Androgen receptors frequently are expressed in breast carcinomas: Potential relevance to new therapeutic strategies
    • Moinfar F, Okcu M, Tsybrovskyy O, et al. Androgen receptors frequently are expressed in breast carcinomas: potential relevance to new therapeutic strategies. Cancer. 2003;98(4):703-711.
    • (2003) Cancer , vol.98 , Issue.4 , pp. 703-711
    • Moinfar, F.1    Okcu, M.2    Tsybrovskyy, O.3
  • 32
    • 84892632994 scopus 로고    scopus 로고
    • Androgen receptor expres­sion and outcomes in early breast cancer: A systematic review and meta-analysis
    • Vera-Badillo FE, Templeton AJ, de Gouveia P, et al. Androgen receptor expres­sion and outcomes in early breast cancer: a systematic review and meta-analysis. J Natl Cancer Inst. 2014;106(1):djt319.
    • (2014) J Natl Cancer Inst , vol.106 , Issue.1
    • Vera-Badillo, F.E.1    Templeton, A.J.2    de Gouveia, P.3
  • 33
    • 84896710159 scopus 로고    scopus 로고
    • Loss of androgen receptor expression predicts early recurrence in triple-negative and basal-like breast cancer
    • Thike AA, Yong-Zheng Chong L, Cheok PY, et al. Loss of androgen receptor expression predicts early recurrence in triple-negative and basal-like breast cancer. Mod Pathol. 2014;27(3):352-360.
    • (2014) Mod Pathol , vol.27 , Issue.3 , pp. 352-360
    • Thike, A.A.1    Yong-Zheng Chong, L.2    Cheok, P.Y.3
  • 34
    • 84896702428 scopus 로고    scopus 로고
    • Androgen receptor-positive triple negative breast cancer: A unique breast cancer subtype
    • McGhan LJ, McCullough AE, Protheroe CA, et al. Androgen receptor-positive triple negative breast cancer: a unique breast cancer subtype. Ann Surg Oncol. 2014;21(2):361-367.
    • (2014) Ann Surg Oncol , vol.21 , Issue.2 , pp. 361-367
    • McGhan, L.J.1    McCullough, A.E.2    Protheroe, C.A.3
  • 36
    • 84895525356 scopus 로고    scopus 로고
    • Androgen receptor status is a prog­nostic marker in non-basal triple negative breast cancers and determines novel therapeutic options
    • Gasparini P, Fassan M, Cascione L, et al. Androgen receptor status is a prog­nostic marker in non-basal triple negative breast cancers and determines novel therapeutic options. PLoS One. 2014;9(2):e88525.
    • (2014) Plos One , vol.9 , Issue.2
    • Gasparini, P.1    Fassan, M.2    Cascione, L.3
  • 37
    • 77149129286 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Role of the androgen recep­tor
    • Gucalp A, Traina TA. Triple-negative breast cancer: role of the androgen recep­tor. Cancer J. 2010;16(1):62-65.
    • (2010) Cancer J , vol.16 , Issue.1 , pp. 62-65
    • Gucalp, A.1    Traina, T.A.2
  • 38
    • 84876304628 scopus 로고    scopus 로고
    • Expression of androgen receptors in triple negative breast carcinomas
    • Mrklić I, Pogorelić Z, Capkun V, Tomić S. Expression of androgen receptors in triple negative breast carcinomas. Acta Histochem. 2013;115(4):344-348.
    • (2013) Acta Histochem , vol.115 , Issue.4 , pp. 344-348
    • Mrklić, I.1    Pogorelić, Z.2    Capkun, V.3    Tomić, S.4
  • 39
    • 84864447342 scopus 로고    scopus 로고
    • Minireview: The androgen receptor in breast tissues: Growth inhibitor, tumor suppressor, oncogene?
    • Hickey TE, Robinson JL, Carroll JS, Tilley WD. Minireview: The androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene? Mol Endocrinol. 2012;26(8):1252-1267.
    • (2012) Mol Endocrinol , vol.26 , Issue.8 , pp. 1252-1267
    • Hickey, T.E.1    Robinson, J.L.2    Carroll, J.S.3    Tilley, W.D.4
  • 40
    • 84884531675 scopus 로고    scopus 로고
    • Effect of androgens on different breast cancer cells co-cultured with or without breast adipose fibro­blasts
    • Chottanapund S, Van Duursen MB, Navasumrit P, et al. Effect of androgens on different breast cancer cells co-cultured with or without breast adipose fibro­blasts. J Steroid Biochem Mol Biol. 2013;138:54-62.
    • (2013) J Steroid Biochem Mol Biol , vol.138 , pp. 54-62
    • Chottanapund, S.1    Van Duursen, M.B.2    Navasumrit, P.3
  • 41
    • 80755169616 scopus 로고    scopus 로고
    • Triple negative breast cancer cell lines: One tool in the search for better treatment of triple negative breast cancer
    • Chavez KJ, Garimella SV, Lipkowitz S. Triple negative breast cancer cell lines: one tool in the search for better treatment of triple negative breast cancer. Breast Dis. 2010;32(1-2):35-48.
    • (2010) Breast Dis , vol.32 , Issue.1-2 , pp. 35-48
    • Chavez, K.J.1    Garimella, S.V.2    Lipkowitz, S.3
  • 42
    • 33745603978 scopus 로고    scopus 로고
    • An estrogen receptor-negative breast can­cer subset characterized by a hormonally regulated transcriptional program and response to androgen
    • Doane AS, Danso M, Lal P, et al. An estrogen receptor-negative breast can­cer subset characterized by a hormonally regulated transcriptional program and response to androgen. Oncogene. 2006;25(28):3994-4008.
    • (2006) Oncogene. , vol.25 , Issue.28 , pp. 3994-4008
    • Doane, A.S.1    Danso, M.2    Lal, P.3
  • 43
    • 84892633593 scopus 로고    scopus 로고
    • Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide
    • Cochrane DR, Bernales S, Jacobsen BM, et al. Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide. Breast Cancer Res. 2014;16(1):R7.
    • (2014) Breast Cancer Res , vol.16 , Issue.1
    • Cochrane, D.R.1    Bernales, S.2    Jacobsen, B.M.3
  • 44
    • 44949129660 scopus 로고    scopus 로고
    • Androgen receptor expresion in breast cancer: Relationship with clinicopathological characteristics of the tumors, prognosis, and expression of metalloproteases and their inhibitors
    • Gonzalez LO, Corte MD, Vazquez J, et al. Androgen receptor expresion in breast cancer: relationship with clinicopathological characteristics of the tumors, prognosis, and expression of metalloproteases and their inhibitors. BMC Cancer. 2008;8:149.
    • (2008) BMC Cancer , vol.8
    • Gonzalez, L.O.1    Corte, M.D.2    Vazquez, J.3
  • 45
    • 0242300581 scopus 로고    scopus 로고
    • Androgen recep­tor expression in estrogen receptor-negative breast cancer. Immunohistochemical, clinical, and prognostic associations
    • Agoff SN, Swanson PE, Linden H, Hawes SE, Lawton TJ. Androgen recep­tor expression in estrogen receptor-negative breast cancer. Immunohistochemical, clinical, and prognostic associations. Am J Clin Pathol. 2003;120(5):725-731.
    • (2003) Am J Clin Pathol , vol.120 , Issue.5 , pp. 725-731
    • Agoff, S.N.1    Swanson, P.E.2    Linden, H.3    Hawes, S.E.4    Lawton, T.J.5
  • 46
    • 27644442226 scopus 로고    scopus 로고
    • Immunohistochemical study of androgen receptors in breast carcinoma. Evidence of their frequent expression in lobular carcinoma
    • Riva C, Dainese E, Caprara G, et al. Immunohistochemical study of androgen receptors in breast carcinoma. Evidence of their frequent expression in lobular carcinoma. Virchows Arch. 2005;447(4):695-700.
    • (2005) Virchows Arch , vol.447 , Issue.4 , pp. 695-700
    • Riva, C.1    Dainese, E.2    Caprara, G.3
  • 47
    • 79953315588 scopus 로고    scopus 로고
    • Androgen receptor expression and breast cancer survival in postmenopausal women
    • Hu R, Dawood S, Holmes MD, et al. Androgen receptor expression and breast cancer survival in postmenopausal women. Clin Cancer Res. 2011;17(7):1867-1874.
    • (2011) Clin Cancer Res , vol.17 , Issue.7 , pp. 1867-1874
    • Hu, R.1    Dawood, S.2    Holmes, M.D.3
  • 48
    • 78651446711 scopus 로고    scopus 로고
    • Expression and clinical significance of andro­gen receptor in triple negative breast cancer
    • Luo X, Shi YX, Li ZM, Jiang WQ. Expression and clinical significance of andro­gen receptor in triple negative breast cancer. Chin J Cancer. 2010;29(6):585-590.
    • (2010) Chin J Cancer , vol.29 , Issue.6 , pp. 585-590
    • Luo, X.1    Shi, Y.X.2    Li, Z.M.3    Jiang, W.Q.4
  • 50
    • 84867024734 scopus 로고    scopus 로고
    • Decreased androgen receptor expression is associated with distant metastases in patients with androgen receptor-expressing triple-negative breast carcinoma
    • Sutton LM, Cao D, Sarode V, et al. Decreased androgen receptor expression is associated with distant metastases in patients with androgen receptor-expressing triple-negative breast carcinoma. Am J Clin Pathol. 2012;138(4):511-516.
    • (2012) Am J Clin Pathol , vol.138 , Issue.4 , pp. 511-516
    • Sutton, L.M.1    Cao, D.2    Sarode, V.3
  • 51
    • 84891752262 scopus 로고    scopus 로고
    • The impact of androgen receptor expression on breast cancer survival: A retrospective study and meta-analysis
    • Qu Q, Mao Y, Fei XC, Shen KW. The impact of androgen receptor expression on breast cancer survival: a retrospective study and meta-analysis. PLoS One. 2013;8(12):e82650.
    • (2013) Plos One , vol.8 , Issue.12
    • Qu, Q.1    Mao, Y.2    Fei, X.C.3    Shen, K.W.4
  • 52
    • 84903512336 scopus 로고    scopus 로고
    • Androgen receptor expression in early triple-negative breast cancer: Clinical significance and prognostic associations
    • Pistelli M, Caramanti M, Biscotti T, et al. Androgen receptor expression in early triple-negative breast cancer: clinical significance and prognostic associations. Cancers (Basel). 2014;6(3):1351-1362.
    • (2014) Cancers (Basel) , vol.6 , Issue.3 , pp. 1351-1362
    • Pistelli, M.1    Caramanti, M.2    Biscotti, T.3
  • 53
    • 79960989401 scopus 로고    scopus 로고
    • Androgen receptor expression is significantly associated with better outcomes in estrogen receptor-positive breast cancers
    • Park S, Koo JS, Kim MS, et al. Androgen receptor expression is significantly associated with better outcomes in estrogen receptor-positive breast cancers. Ann Oncol. 2011;22(8):1755-1762.
    • (2011) Ann Oncol , vol.22 , Issue.8 , pp. 1755-1762
    • Park, S.1    Koo, J.S.2    Kim, M.S.3
  • 54
    • 85027918496 scopus 로고    scopus 로고
    • Androgen receptor expression predicts decreased survival in early stage triple-negative breast cancer
    • Choi JE, Kang SH, Lee SJ, Bae YK. Androgen receptor expression predicts decreased survival in early stage triple-negative breast cancer. Ann Surg Oncol. 2015;22(1):82-89.
    • (2015) Ann Surg Oncol , vol.22 , Issue.1 , pp. 82-89
    • Choi, J.E.1    Kang, S.H.2    Lee, S.J.3    Bae, Y.K.4
  • 55
    • 79961029891 scopus 로고    scopus 로고
    • Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1
    • Robinson JL, Macarthur S, Ross-Innes CS, et al. Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1. EMBO J. 2011;30(15):3019-3027.
    • (2011) EMBO J , vol.30 , Issue.15 , pp. 3019-3027
    • Robinson, J.L.1    Macarthur, S.2    Ross-Innes, C.S.3
  • 56
    • 22744448864 scopus 로고    scopus 로고
    • Identification of molecular apocrine breast tumours by microarray analysis
    • Farmer P, Bonnefoi H, Becette V, et al. Identification of molecular apocrine breast tumours by microarray analysis. Oncogene. 2005;24(29):4660-4671.
    • (2005) Oncogene , vol.24 , Issue.29 , pp. 4660-4671
    • Farmer, P.1    Bonnefoi, H.2    Becette, V.3
  • 57
    • 84877272007 scopus 로고    scopus 로고
    • Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15
    • Lehmann-Che J, Hamy AS, Porcher R, et al. Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15. Breast Cancer Res. 2013;15(3):R37.
    • (2013) Breast Cancer Res , vol.15 , Issue.3
    • Lehmann-Che, J.1    Hamy, A.S.2    Porcher, R.3
  • 58
    • 39149111633 scopus 로고    scopus 로고
    • Preoperative chemotherapy: Updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27
    • Rastogi P, Anderson SJ, Bear HD, et al. Preoperative chemotherapy: updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27. J Clin Oncol. 2008;26(5):778-785.
    • (2008) J Clin Oncol , vol.26 , Issue.5 , pp. 778-785
    • Rastogi, P.1    Erson, S.J.2    Bear, H.D.3
  • 59
    • 84904188903 scopus 로고    scopus 로고
    • Pathological complete response and long-term clinical benefit in breast cancer: The CTNeoBC pooled analysis
    • Cortazar P, Zhang L, Untch M, et al. Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis. Lancet. 2014;384(9938):164-172.
    • (2014) Lancet , vol.384 , Issue.9938 , pp. 164-172
    • Cortazar, P.1    Zhang, L.2    Untch, M.3
  • 60
    • 41649102048 scopus 로고    scopus 로고
    • Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
    • Liedtke C, Mazouni C, Hess KR, et al. Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol. 2008;26(8):1275-1281.
    • (2008) J Clin Oncol , vol.26 , Issue.8 , pp. 1275-1281
    • Liedtke, C.1    Mazouni, C.2    Hess, K.R.3
  • 61
    • 82955187707 scopus 로고    scopus 로고
    • Androgen receptor expression in primary breast cancer and its predictive and prognostic value in patients treated with neoadjuvant chemotherapy
    • Loibl S, Müller BM, von Minckwitz G, et al. Androgen receptor expression in primary breast cancer and its predictive and prognostic value in patients treated with neoadjuvant chemotherapy. Breast Cancer Res Treat. 2011;130(2):477-487.
    • (2011) Breast Cancer Res Treat , vol.130 , Issue.2 , pp. 477-487
    • Loibl, S.1    Müller, B.M.2    Von Minckwitz, G.3
  • 62
    • 77957710541 scopus 로고    scopus 로고
    • Effect of neoadjuvant anthracycline-taxane-based chemotherapy in different biological breast cancer phenotypes: Overall results from the GeparTrio study
    • Huober J, von Minckwitz G, Denkert C, et al. Effect of neoadjuvant anthracycline-taxane-based chemotherapy in different biological breast cancer phenotypes: overall results from the GeparTrio study. Breast Cancer Res Treat. 2010;124(1):133-140.
    • (2010) Breast Cancer Res Treat , vol.124 , Issue.1 , pp. 133-140
    • Huober, J.1    Von Minckwitz, G.2    Denkert, C.3
  • 63
    • 84865191389 scopus 로고    scopus 로고
    • I-SPY 1 TRIAL Investigators. Chemotherapy response and recurrence-free survival in neoadjuvant breast can­cer depends on biomarker profiles: Results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)
    • Esserman LJ, Berry DA, Cheang MC, et al; I-SPY 1 TRIAL Investigators. Chemotherapy response and recurrence-free survival in neoadjuvant breast can­cer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657). Breast Cancer Res Treat. 2012;132(3):1049-1062.
    • (2012) Breast Cancer Res Treat , vol.132 , Issue.3 , pp. 1049-1062
    • Esserman, L.J.1    Berry, D.A.2    Cheang, M.C.3
  • 65
    • 0023733949 scopus 로고
    • Phase II study of flutamide in patients with metastatic breast cancer. A National Cancer Institute of Canada Clinical Trials Group study
    • Perrault DJ, Logan DM, Stewart DJ, Bramwell VH, Paterson AH, Eisen­hauer EA. Phase II study of flutamide in patients with metastatic breast cancer. A National Cancer Institute of Canada Clinical Trials Group study. Invest New Drugs. 1988;6(3):207-210.
    • (1988) Invest New Drugs , vol.6 , Issue.3 , pp. 207-210
    • Perrault, D.J.1    Logan, D.M.2    Stewart, D.J.3    Bramwell, V.H.4    Paterson, A.H.5    Eisen­Hauer, E.A.6
  • 66
    • 0023829866 scopus 로고
    • A phase II clinical trial of flutamide in the treatment of advanced breast cancer
    • Zhao TP, He GF. A phase II clinical trial of flutamide in the treatment of advanced breast cancer. Tumori. 1988;74(1):53-56.
    • (1988) Tumori , vol.74 , Issue.1 , pp. 53-56
    • Zhao, T.P.1    He, G.F.2
  • 67
    • 84886425456 scopus 로고    scopus 로고
    • Translational Breast Cancer Research Consortium (TBCRC 011). Phase II trial of bicalutamide in patients with andro­gen receptor-positive, estrogen receptor-negative metastatic breast cancer
    • Gucalp A, Tolaney S, Isakoff SJ, et al; Translational Breast Cancer Research Consortium (TBCRC 011). Phase II trial of bicalutamide in patients with andro­gen receptor-positive, estrogen receptor-negative metastatic breast cancer. Clin Cancer Res. 2013;19(19):5505-5512.
    • (2013) Clin Cancer Res , vol.19 , Issue.19 , pp. 5505-5512
    • Gucalp, A.1    Tolaney, S.2    Isakoff, S.J.3
  • 68
    • 65649090203 scopus 로고    scopus 로고
    • Development of a second-generation antiandrogen for treatment of advanced prostate cancer
    • Tran C, Ouk S, Clegg NJ, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009;324(5928):787-790.
    • (2009) Science , vol.324 , Issue.5928 , pp. 787-790
    • Tran, C.1    Ouk, S.2    Clegg, N.J.3
  • 69
    • 84904871070 scopus 로고    scopus 로고
    • PREVAIL Investigators. Enzalutamide in metastatic prostate cancer before chemotherapy
    • Beer TM, Armstrong AJ, Rathkopf DE, et al; PREVAIL Investigators. Enzalutamide in metastatic prostate cancer before chemotherapy. N Engl J Med. 2014;371(5):424-433.
    • (2014) N Engl J Med , vol.371 , Issue.5 , pp. 424-433
    • Beer, T.M.1    Armstrong, A.J.2    Rathkopf, D.E.3
  • 70
    • 84866770294 scopus 로고    scopus 로고
    • AFFIRM Investigators. Increased sur­vival with enzalutamide in prostate cancer after chemotherapy
    • Scher HI, Fizazi K, Saad F, et al; AFFIRM Investigators. Increased sur­vival with enzalutamide in prostate cancer after chemotherapy. N Engl J Med. 2012;367(13):1187-1197.
    • (2012) N Engl J Med , vol.367 , Issue.13 , pp. 1187-1197
    • Scher, H.I.1    Fizazi, K.2    Saad, F.3
  • 71
    • 84940467449 scopus 로고    scopus 로고
    • Results from a phase 2 study of enzalu­tamide (Enza), an androgen receptor (AR) inhibitor, in advanced AR+ triple-negative breast cancer [ASCO abstract 1003]
    • Traina TA, Miller K, Yardley DA, et al. Results from a phase 2 study of enzalu­tamide (enza), an androgen receptor (AR) inhibitor, in advanced AR+ triple-negative breast cancer [ASCO abstract 1003]. J Clin Oncol. 2015;33(15).
    • (2015) J Clin Oncol , vol.33 , Issue.15
    • Traina, T.A.1    Miller, K.2    Yardley, D.A.3
  • 72
    • 84988022199 scopus 로고    scopus 로고
    • A novel biomarker to predict sensitivity to enzalutamide in TNBC [ASCO abstract 1083]
    • Parker JS, Peterson A, Tudor JC, et al. A novel biomarker to predict sensitivity to enzalutamide in TNBC [ASCO abstract 1083]. J Clin Oncol. 2015;33(15).
    • (2015) J Clin Oncol , vol.33 , Issue.15
    • Parker, J.S.1    Peterson, A.2    Tudor, J.C.3
  • 73
    • 84925006635 scopus 로고    scopus 로고
    • Phase III, randomized, double-blind, multicenter trial comparing orteronel (TAK-700) plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer that has progressed during or after docetaxel-based therapy: ELM-PC 5
    • Fizazi K, Jones R, Oudard S, et al. Phase III, randomized, double-blind, multicenter trial comparing orteronel (TAK-700) plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer that has progressed during or after docetaxel-based therapy: ELM-PC 5. J Clin Oncol. 2015;33(7):723-731.
    • (2015) J Clin Oncol , vol.33 , Issue.7 , pp. 723-731
    • Fizazi, K.1    Jones, R.2    Oudard, S.3
  • 74
    • 84925016549 scopus 로고    scopus 로고
    • ELM-PC 4 investigators. Orteronel plus pred­nisone in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (ELM-PC 4): A double-blind, multicentre, phase 3, randomised, placebo-controlled trial
    • Saad F, Fizazi K, Jinga V, et al; ELM-PC 4 investigators. Orteronel plus pred­nisone in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (ELM-PC 4): a double-blind, multicentre, phase 3, randomised, placebo-controlled trial. Lancet Oncol. 2015;16(3):338-348.
    • (2015) Lancet Oncol , vol.16 , Issue.3 , pp. 338-348
    • Saad, F.1    Fizazi, K.2    Jinga, V.3
  • 76
    • 84922227588 scopus 로고    scopus 로고
    • Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer
    • Toren PJ, Kim S, Pham S, et al. Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer. Mol Cancer Ther. 2015;14(1):59-69.
    • (2015) Mol Cancer Ther , vol.14 , Issue.1 , pp. 59-69
    • Toren, P.J.1    Kim, S.2    Pham, S.3
  • 78
    • 84919875495 scopus 로고    scopus 로고
    • PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors
    • Lehmann BD, Bauer JA, Schafer JM, et al. PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors. Breast Cancer Res. 2014;16(4):406.
    • (2014) Breast Cancer Res , vol.16 , Issue.4
    • Lehmann, B.D.1    Bauer, J.A.2    Schafer, J.M.3
  • 80
    • 84959852003 scopus 로고    scopus 로고
    • The history and future of target­ing cyclin-dependent kinases in cancer therapy
    • Asghar U, Witkiewicz AK, Turner NC, Knudsen ES. The history and future of target­ing cyclin-dependent kinases in cancer therapy. Nat Rev Drug Discov. 2015;14(2):130-146.
    • (2015) Nat Rev Drug Discov , vol.14 , Issue.2 , pp. 130-146
    • Asghar, U.1    Witkiewicz, A.K.2    Turner, N.C.3    Knudsen, E.S.4
  • 81
    • 0028960821 scopus 로고
    • Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer
    • Dickson C, Fantl V, Gillett C, et al. Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer. Cancer Lett. 1995;90(1):43-50.
    • (1995) Cancer Lett , vol.90 , Issue.1 , pp. 43-50
    • Dickson, C.1    Fantl, V.2    Gillett, C.3
  • 83
    • 84922369296 scopus 로고    scopus 로고
    • The cyclin-dependent kinase 4/6 inhibitor pal­bociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): A randomised phase 2 study
    • Finn RS, Crown JP, Lang I, et al. The cyclin-dependent kinase 4/6 inhibitor pal­bociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study. Lancet Oncol. 2015;16(1):25-35.
    • (2015) Lancet Oncol , vol.16 , Issue.1 , pp. 25-35
    • Finn, R.S.1    Crown, J.P.2    Lang, I.3
  • 84
    • 84937042338 scopus 로고    scopus 로고
    • Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer
    • PALOMA3 Study Group
    • Turner NC, Ro J, André F, et al; PALOMA3 Study Group. Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer. N Engl J Med. 2015;373(3):209-219.
    • (2015) N Engl J Med , vol.373 , Issue.3 , pp. 209-219
    • Turner, N.C.1    Ro, J.2    André, F.3
  • 85
    • 84961595942 scopus 로고    scopus 로고
    • Identification of subtypes of triple negative breast cancer (TNBC) that are sensitive to CDK4/6 inhibition [ASCO abstract 11098]
    • Asghar U, Herrera-Abreu MT, Cutts R, et al. Identification of subtypes of triple negative breast cancer (TNBC) that are sensitive to CDK4/6 inhibition [ASCO abstract 11098]. J Clin Oncol. 2015;33(15).
    • (2015) J Clin Oncol , vol.33 , Issue.15
    • Asghar, U.1    Herrera-Abreu, M.T.2    Cutts, R.3
  • 86
    • 84885214146 scopus 로고    scopus 로고
    • An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (Enzalutamide)
    • Korpal M, Korn JM, Gao X, et al. An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide). Cancer Discov. 2013;3(9):1030-1043.
    • (2013) Cancer Discov , vol.3 , Issue.9 , pp. 1030-1043
    • Korpal, M.1    Korn, J.M.2    Gao, X.3
  • 87
    • 84961632175 scopus 로고    scopus 로고
    • Phase III, randomized, double-blind, placebo-controlled study of ribociclib (LEE011) in combination with either tamoxifen and goserelin or a non-steroidal aromatase inhibitor (NSAI) and goserelin for the treat­ment of premenopausal women with HR+, HER2– advanced breast cancer (aBC): MONALEESA-7 [ASCO abstract TPS625]
    • Tripathy D, Bardia A, Hurvitz SA, et al. Phase III, randomized, double-blind, placebo-controlled study of ribociclib (LEE011) in combination with either tamoxifen and goserelin or a non-steroidal aromatase inhibitor (NSAI) and goserelin for the treat­ment of premenopausal women with HR+, HER2– advanced breast cancer (aBC): MONALEESA-7 [ASCO abstract TPS625]. J Clin Oncol. 2015;33(15).
    • (2015) J Clin Oncol , vol.33 , Issue.15
    • Tripathy, D.1    Bardia, A.2    Hurvitz, S.A.3


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