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Volumn 16, Issue 1, 2014, Pages

Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANDROGEN RECEPTOR ANTAGONIST; ANILIDE; ANTIANDROGEN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; BICALUTAMIDE; ENZALUTAMIDE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA, HUMAN; NITRILE; PHENYLTHIOHYDANTOIN; TAMOXIFEN; TOLUENESULFONIC ACID DERIVATIVE;

EID: 84892633593     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr3599     Document Type: Article
Times cited : (324)

References (57)
  • 2
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • 10.1172/JCI45014, 3127435, 21633166
    • Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, Pietenpol JA. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011, 121:2750-2767. 10.1172/JCI45014, 3127435, 21633166.
    • (2011) J Clin Invest , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3    Sanders, M.E.4    Chakravarthy, A.B.5    Shyr, Y.6    Pietenpol, J.A.7
  • 3
    • 79959998479 scopus 로고    scopus 로고
    • Androgen receptor expression in breast cancer in relation to molecular phenotype: results from the Nurses' Health Study
    • 10.1038/modpathol.2011.54, 3128675, 21552212
    • Collins LC, Cole KS, Marotti JD, Hu R, Schnitt SJ, Tamimi RM. Androgen receptor expression in breast cancer in relation to molecular phenotype: results from the Nurses' Health Study. Mod Pathol 2011, 24:924-931. 10.1038/modpathol.2011.54, 3128675, 21552212.
    • (2011) Mod Pathol , vol.24 , pp. 924-931
    • Collins, L.C.1    Cole, K.S.2    Marotti, J.D.3    Hu, R.4    Schnitt, S.J.5    Tamimi, R.M.6
  • 4
    • 77649188673 scopus 로고    scopus 로고
    • Expression of androgen receptors in primary breast cancer
    • 10.1093/annonc/mdp510, 19887463
    • Park S, Koo J, Park HS, Kim JH, Choi SY, Lee JH, Park BW, Lee KS. Expression of androgen receptors in primary breast cancer. Ann Oncol 2010, 21:488-492. 10.1093/annonc/mdp510, 19887463.
    • (2010) Ann Oncol , vol.21 , pp. 488-492
    • Park, S.1    Koo, J.2    Park, H.S.3    Kim, J.H.4    Choi, S.Y.5    Lee, J.H.6    Park, B.W.7    Lee, K.S.8
  • 6
    • 84863892191 scopus 로고    scopus 로고
    • FACT: an open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer
    • 10.1200/JCO.2011.38.1095, 22370325
    • Bergh J, Jonsson PE, Lidbrink EK, Trudeau M, Eiermann W, Brattstrom D, Lindemann JP, Wiklund F, Henriksson R. FACT: an open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer. J Clin Oncol 2012, 30:1919-1925. 10.1200/JCO.2011.38.1095, 22370325.
    • (2012) J Clin Oncol , vol.30 , pp. 1919-1925
    • Bergh, J.1    Jonsson, P.E.2    Lidbrink, E.K.3    Trudeau, M.4    Eiermann, W.5    Brattstrom, D.6    Lindemann, J.P.7    Wiklund, F.8    Henriksson, R.9
  • 8
    • 56549121407 scopus 로고    scopus 로고
    • Estrogen regulated gene expression in response to neoadjuvant endocrine therapy of breast cancers: tamoxifen agonist effects dominate in the presence of an aromatase inhibitor
    • 10.1007/s10549-008-9923-6, 18338247
    • Harvell DM, Richer JK, Singh M, Spoelstra N, Finlayson C, Borges VF, Elias AD, Horwitz KB. Estrogen regulated gene expression in response to neoadjuvant endocrine therapy of breast cancers: tamoxifen agonist effects dominate in the presence of an aromatase inhibitor. Breast Cancer Res Treat 2008, 112:489-501. 10.1007/s10549-008-9923-6, 18338247.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 489-501
    • Harvell, D.M.1    Richer, J.K.2    Singh, M.3    Spoelstra, N.4    Finlayson, C.5    Borges, V.F.6    Elias, A.D.7    Horwitz, K.B.8
  • 11
    • 0024268065 scopus 로고
    • Effects of the aromatase inhibitor 4-hydroxyandrostenedione and the antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors
    • 10.1007/BF01811241, 3147727
    • Spinola PG, Marchetti B, Merand Y, Belanger A, Labrie F. Effects of the aromatase inhibitor 4-hydroxyandrostenedione and the antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors. Breast Cancer Res Treat 1988, 12:287-296. 10.1007/BF01811241, 3147727.
    • (1988) Breast Cancer Res Treat , vol.12 , pp. 287-296
    • Spinola, P.G.1    Marchetti, B.2    Merand, Y.3    Belanger, A.4    Labrie, F.5
  • 12
    • 77449140006 scopus 로고    scopus 로고
    • Androgens and the breast
    • 10.1186/bcr2413, 2790857, 19889198
    • Dimitrakakis C, Bondy C. Androgens and the breast. Breast Cancer Res 2009, 11:212. 10.1186/bcr2413, 2790857, 19889198.
    • (2009) Breast Cancer Res , vol.11 , pp. 212
    • Dimitrakakis, C.1    Bondy, C.2
  • 13
    • 82955249033 scopus 로고    scopus 로고
    • Androgens and musculoskeletal symptoms among breast cancer patients on aromatase inhibitor therapy
    • 10.1007/s10549-011-1611-2, 21647676
    • Gallicchio L, Macdonald R, Wood B, Rushovich E, Helzlsouer KJ. Androgens and musculoskeletal symptoms among breast cancer patients on aromatase inhibitor therapy. Breast Cancer Res Treat 2011, 130:569-577. 10.1007/s10549-011-1611-2, 21647676.
    • (2011) Breast Cancer Res Treat , vol.130 , pp. 569-577
    • Gallicchio, L.1    Macdonald, R.2    Wood, B.3    Rushovich, E.4    Helzlsouer, K.J.5
  • 14
    • 0035666689 scopus 로고    scopus 로고
    • High dehydroepiandrosterone-sulfate predicts breast cancer progression during new aromatase inhibitor therapy and stimulates breast cancer cell growth in tissue culture: a renewed role for adrenalectomy
    • 10.1067/msy.2001.118378, 11742322
    • Morris KT, Toth-Fejel S, Schmidt J, Fletcher WS, Pommier RF. High dehydroepiandrosterone-sulfate predicts breast cancer progression during new aromatase inhibitor therapy and stimulates breast cancer cell growth in tissue culture: a renewed role for adrenalectomy. Surgery 2001, 130:947-953. 10.1067/msy.2001.118378, 11742322.
    • (2001) Surgery , vol.130 , pp. 947-953
    • Morris, K.T.1    Toth-Fejel, S.2    Schmidt, J.3    Fletcher, W.S.4    Pommier, R.F.5
  • 15
    • 76349117455 scopus 로고    scopus 로고
    • Androgen receptor in breast cancer: expression in estrogen receptor-positive tumors and in estrogen receptor-negative tumors with apocrine differentiation
    • 10.1038/modpathol.2009.159, 19898421
    • Niemeier LA, Dabbs DJ, Beriwal S, Striebel JM, Bhargava R. Androgen receptor in breast cancer: expression in estrogen receptor-positive tumors and in estrogen receptor-negative tumors with apocrine differentiation. Mod Pathol 2010, 23:205-212. 10.1038/modpathol.2009.159, 19898421.
    • (2010) Mod Pathol , vol.23 , pp. 205-212
    • Niemeier, L.A.1    Dabbs, D.J.2    Beriwal, S.3    Striebel, J.M.4    Bhargava, R.5
  • 16
    • 84860496688 scopus 로고    scopus 로고
    • Apocrine Carcinoma as Triple-negative Breast Cancer: Novel Definition of Apocrine-type Carcinoma as Estrogen/Progesterone Receptor-negative and Androgen Receptor-positive Invasive Ductal Carcinoma
    • 10.1093/jjco/hys034, 22450930
    • Tsutsumi Y. Apocrine Carcinoma as Triple-negative Breast Cancer: Novel Definition of Apocrine-type Carcinoma as Estrogen/Progesterone Receptor-negative and Androgen Receptor-positive Invasive Ductal Carcinoma. Jpn J Clin Oncol 2012, 42:375-386. 10.1093/jjco/hys034, 22450930.
    • (2012) Jpn J Clin Oncol , vol.42 , pp. 375-386
    • Tsutsumi, Y.1
  • 17
    • 33745603978 scopus 로고    scopus 로고
    • An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen
    • 10.1038/sj.onc.1209415, 16491124
    • Doane AS, Danso M, Lal P, Donaton M, Zhang L, Hudis C, Gerald WL. An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen. Oncogene 2006, 25:3994-4008. 10.1038/sj.onc.1209415, 16491124.
    • (2006) Oncogene , vol.25 , pp. 3994-4008
    • Doane, A.S.1    Danso, M.2    Lal, P.3    Donaton, M.4    Zhang, L.5    Hudis, C.6    Gerald, W.L.7
  • 19
    • 79961029891 scopus 로고    scopus 로고
    • Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1
    • 10.1038/emboj.2011.216, 3160190, 21701558
    • Robinson JL, Macarthur S, Ross-Innes CS, Tilley WD, Neal DE, Mills IG, Carroll JS. Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1. Embo J 2011, 30:3019-3027. 10.1038/emboj.2011.216, 3160190, 21701558.
    • (2011) Embo J , vol.30 , pp. 3019-3027
    • Robinson, J.L.1    Macarthur, S.2    Ross-Innes, C.S.3    Tilley, W.D.4    Neal, D.E.5    Mills, I.G.6    Carroll, J.S.7
  • 20
    • 79960050587 scopus 로고    scopus 로고
    • Targeting androgen receptor in estrogen receptor-negative breast cancer
    • 10.1016/j.ccr.2011.05.026, 3180861, 21741601
    • Ni M, Chen Y, Lim E, Wimberly H, Bailey ST, Imai Y, Rimm DL, Liu XS, Brown M. Targeting androgen receptor in estrogen receptor-negative breast cancer. Cancer Cell 2011, 20:119-131. 10.1016/j.ccr.2011.05.026, 3180861, 21741601.
    • (2011) Cancer Cell , vol.20 , pp. 119-131
    • Ni, M.1    Chen, Y.2    Lim, E.3    Wimberly, H.4    Bailey, S.T.5    Imai, Y.6    Rimm, D.L.7    Liu, X.S.8    Brown, M.9
  • 22
    • 0037135630 scopus 로고    scopus 로고
    • Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor
    • 10.1074/jbc.M203310200, 12015321
    • Masiello D, Cheng S, Bubley GJ, Lu ML, Balk SP. Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor. J Biol Chem 2002, 277:26321-26326. 10.1074/jbc.M203310200, 12015321.
    • (2002) J Biol Chem , vol.277 , pp. 26321-26326
    • Masiello, D.1    Cheng, S.2    Bubley, G.J.3    Lu, M.L.4    Balk, S.P.5
  • 23
    • 0028256111 scopus 로고
    • Prostate-specific antigen decline after casodex withdrawal: evidence for an antiandrogen withdrawal syndrome
    • 10.1016/0090-4295(94)90092-2, 7510915
    • Small EJ, Carroll PR. Prostate-specific antigen decline after casodex withdrawal: evidence for an antiandrogen withdrawal syndrome. Urology 1994, 43:408-410. 10.1016/0090-4295(94)90092-2, 7510915.
    • (1994) Urology , vol.43 , pp. 408-410
    • Small, E.J.1    Carroll, P.R.2
  • 26
    • 0037055539 scopus 로고    scopus 로고
    • Characterization of androgen receptor and nuclear receptor co-regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3
    • 10.1002/ijc.10520, 12124798
    • Magklara A, Brown TJ, Diamandis EP. Characterization of androgen receptor and nuclear receptor co-regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3. Int J Cancer 2002, 100:507-514. 10.1002/ijc.10520, 12124798.
    • (2002) Int J Cancer , vol.100 , pp. 507-514
    • Magklara, A.1    Brown, T.J.2    Diamandis, E.P.3
  • 27
    • 0028033594 scopus 로고
    • The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function
    • 10.1093/nar/22.15.3181, 310294, 8065934
    • Chamberlain NL, Driver ED, Miesfeld RL. The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function. Nucleic Acids Res 1994, 22:3181-3186. 10.1093/nar/22.15.3181, 310294, 8065934.
    • (1994) Nucleic Acids Res , vol.22 , pp. 3181-3186
    • Chamberlain, N.L.1    Driver, E.D.2    Miesfeld, R.L.3
  • 29
    • 0028358348 scopus 로고
    • MDA-MB-453, an androgen-responsive human breast carcinoma cell line with high level androgen receptor expression
    • Hall RE, Birrell SN, Tilley WD, Sutherland RL. MDA-MB-453, an androgen-responsive human breast carcinoma cell line with high level androgen receptor expression. Eur J Cancer 1994, 30A:484-490.
    • (1994) Eur J Cancer , vol.30 A , pp. 484-490
    • Hall, R.E.1    Birrell, S.N.2    Tilley, W.D.3    Sutherland, R.L.4
  • 30
    • 0014764747 scopus 로고
    • Failure of 5-alpha-dihydrotestosterone to elicit estrous behavior in the ovariectomized rabbit
    • 10.1210/endo-86-4-939, 5461020
    • Beyer C, McDonald P, Vidal N. Failure of 5-alpha-dihydrotestosterone to elicit estrous behavior in the ovariectomized rabbit. Endocrinology 1970, 86:939-941. 10.1210/endo-86-4-939, 5461020.
    • (1970) Endocrinology , vol.86 , pp. 939-941
    • Beyer, C.1    McDonald, P.2    Vidal, N.3
  • 32
    • 0142216815 scopus 로고
    • Biological aromatization of steroids
    • Ryan KJ. Biological aromatization of steroids. J Biol Chem 1959, 234:268-272.
    • (1959) J Biol Chem , vol.234 , pp. 268-272
    • Ryan, K.J.1
  • 36
    • 0036192083 scopus 로고    scopus 로고
    • A novel cell line, MDA-kb2, that stably expresses an androgen- and glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists
    • 10.1093/toxsci/66.1.69, 11861974
    • Wilson VS, Bobseine K, Lambright CR, Gray LE. A novel cell line, MDA-kb2, that stably expresses an androgen- and glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists. Toxicol Sci 2002, 66:69-81. 10.1093/toxsci/66.1.69, 11861974.
    • (2002) Toxicol Sci , vol.66 , pp. 69-81
    • Wilson, V.S.1    Bobseine, K.2    Lambright, C.R.3    Gray, L.E.4
  • 38
    • 0026586827 scopus 로고
    • Androgen receptors in operable breast cancer: relation to other steroid hormone receptors, correlations to prognostic factors and predictive value for effect of adjuvant tamoxifen treatment
    • Soreide JA, Lea OA, Varhaug JE, Skarstein A, Kvinnsland S. Androgen receptors in operable breast cancer: relation to other steroid hormone receptors, correlations to prognostic factors and predictive value for effect of adjuvant tamoxifen treatment. Eur J Surg Oncol 1992, 18:112-118.
    • (1992) Eur J Surg Oncol , vol.18 , pp. 112-118
    • Soreide, J.A.1    Lea, O.A.2    Varhaug, J.E.3    Skarstein, A.4    Kvinnsland, S.5
  • 39
    • 84873180884 scopus 로고    scopus 로고
    • Androgen receptor as a targeted therapy for breast cancer
    • 3410582, 22860233
    • Garay JP, Park BH. Androgen receptor as a targeted therapy for breast cancer. Am J Cancer Res 2012, 2:434-445. 3410582, 22860233.
    • (2012) Am J Cancer Res , vol.2 , pp. 434-445
    • Garay, J.P.1    Park, B.H.2
  • 40
    • 84864447342 scopus 로고    scopus 로고
    • Minireview: the androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene?
    • 10.1210/me.2012-1107, 3404296, 22745190
    • Hickey TE, Robinson JL, Carroll JS, Tilley WD. Minireview: the androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene?. Mol Endocrinol 2012, 26:1252-1267. 10.1210/me.2012-1107, 3404296, 22745190.
    • (2012) Mol Endocrinol , vol.26 , pp. 1252-1267
    • Hickey, T.E.1    Robinson, J.L.2    Carroll, J.S.3    Tilley, W.D.4
  • 41
    • 34248148215 scopus 로고    scopus 로고
    • Androgens and androgen receptors: a clinically neglected sector in breast cancer biology
    • 10.1002/jso.20722, 17192921
    • Moe RE, Anderson BO. Androgens and androgen receptors: a clinically neglected sector in breast cancer biology. J Surg Oncol 2007, 95:437-439. 10.1002/jso.20722, 17192921.
    • (2007) J Surg Oncol , vol.95 , pp. 437-439
    • Moe, R.E.1    Anderson, B.O.2
  • 43
    • 0024264118 scopus 로고
    • Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line
    • 10.1007/BF01805942, 3242650
    • Poulin R, Baker D, Labrie F. Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line. Breast Cancer Res Treat 1988, 12:213-225. 10.1007/BF01805942, 3242650.
    • (1988) Breast Cancer Res Treat , vol.12 , pp. 213-225
    • Poulin, R.1    Baker, D.2    Labrie, F.3
  • 44
    • 33747886393 scopus 로고    scopus 로고
    • Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole
    • 10.1158/0008-5472.CAN-05-3984, 16885381
    • Macedo LF, Guo Z, Tilghman SL, Sabnis GJ, Qiu Y, Brodie A. Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole. Cancer Res 2006, 66:7775-7782. 10.1158/0008-5472.CAN-05-3984, 16885381.
    • (2006) Cancer Res , vol.66 , pp. 7775-7782
    • Macedo, L.F.1    Guo, Z.2    Tilghman, S.L.3    Sabnis, G.J.4    Qiu, Y.5    Brodie, A.6
  • 45
    • 44949151486 scopus 로고    scopus 로고
    • Antiproliferative actions of the synthetic androgen, mibolerone, in breast cancer cells are mediated by both androgen and progesterone receptors
    • 10.1016/j.jsbmb.2007.10.014, 18515094
    • Cops EJ, Bianco-Miotto T, Moore NL, Clarke CL, Birrell SN, Butler LM, Tilley WD. Antiproliferative actions of the synthetic androgen, mibolerone, in breast cancer cells are mediated by both androgen and progesterone receptors. J Steroid Biochem Mol Biol 2008, 110:236-243. 10.1016/j.jsbmb.2007.10.014, 18515094.
    • (2008) J Steroid Biochem Mol Biol , vol.110 , pp. 236-243
    • Cops, E.J.1    Bianco-Miotto, T.2    Moore, N.L.3    Clarke, C.L.4    Birrell, S.N.5    Butler, L.M.6    Tilley, W.D.7
  • 47
    • 0021175579 scopus 로고
    • In vitro growth promotion of human mammary carcinoma cells by steroid hormones, tamoxifen, and prolactin
    • Simon WE, Albrecht M, Trams G, Dietel M, Holzel F. In vitro growth promotion of human mammary carcinoma cells by steroid hormones, tamoxifen, and prolactin. J Natl Cancer Inst 1984, 73:313-321.
    • (1984) J Natl Cancer Inst , vol.73 , pp. 313-321
    • Simon, W.E.1    Albrecht, M.2    Trams, G.3    Dietel, M.4    Holzel, F.5
  • 48
    • 0029007560 scopus 로고
    • Testosterone, dihydrotestosterone and oestradiol levels in postmenopausal breast cancer tissues
    • 10.1016/0960-0760(95)00017-T, 7779758
    • Recchione C, Venturelli E, Manzari A, Cavalleri A, Martinetti A, Secreto G. Testosterone, dihydrotestosterone and oestradiol levels in postmenopausal breast cancer tissues. J Steroid Biochem Mol Biol 1995, 52:541-546. 10.1016/0960-0760(95)00017-T, 7779758.
    • (1995) J Steroid Biochem Mol Biol , vol.52 , pp. 541-546
    • Recchione, C.1    Venturelli, E.2    Manzari, A.3    Cavalleri, A.4    Martinetti, A.5    Secreto, G.6
  • 49
    • 0032454317 scopus 로고    scopus 로고
    • Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent
    • 10.1016/S0950-351X(98)80267-X, 10332569
    • Swerdloff RS, Wang C. Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent. Baillieres Clin Endocrinol Metab 1998, 12:501-506. 10.1016/S0950-351X(98)80267-X, 10332569.
    • (1998) Baillieres Clin Endocrinol Metab , vol.12 , pp. 501-506
    • Swerdloff, R.S.1    Wang, C.2
  • 50
    • 0038636392 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells
    • 10.1210/me.2002-0438, 12586845
    • Hall JM, Korach KS. Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells. Mol Endocrinol 2003, 17:792-803. 10.1210/me.2002-0438, 12586845.
    • (2003) Mol Endocrinol , vol.17 , pp. 792-803
    • Hall, J.M.1    Korach, K.S.2
  • 51
    • 67651005771 scopus 로고    scopus 로고
    • Positive feedback activation of estrogen receptors by the CXCL12-CXCR4 pathway
    • 10.1158/0008-5472.CAN-08-4924, 19584281
    • Sauve K, Lepage J, Sanchez M, Heveker N, Tremblay A. Positive feedback activation of estrogen receptors by the CXCL12-CXCR4 pathway. Cancer Res 2009, 69:5793-5800. 10.1158/0008-5472.CAN-08-4924, 19584281.
    • (2009) Cancer Res , vol.69 , pp. 5793-5800
    • Sauve, K.1    Lepage, J.2    Sanchez, M.3    Heveker, N.4    Tremblay, A.5
  • 52
    • 84857141616 scopus 로고    scopus 로고
    • The CXCL12/CXCR4 axis promotes ligand-independent activation of the androgen receptor
    • 10.1016/j.mce.2011.12.015, 3307100, 22245379
    • Kasina S, Macoska JA. The CXCL12/CXCR4 axis promotes ligand-independent activation of the androgen receptor. Mol Cell Endocrinol 2012, 351:249-263. 10.1016/j.mce.2011.12.015, 3307100, 22245379.
    • (2012) Mol Cell Endocrinol , vol.351 , pp. 249-263
    • Kasina, S.1    Macoska, J.A.2
  • 53
    • 8344272750 scopus 로고    scopus 로고
    • Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor
    • 10.1210/me.2004-0245, 15308689
    • Kang Z, Janne OA, Palvimo JJ. Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor. Mol Endocrinol 2004, 18:2633-2648. 10.1210/me.2004-0245, 15308689.
    • (2004) Mol Endocrinol , vol.18 , pp. 2633-2648
    • Kang, Z.1    Janne, O.A.2    Palvimo, J.J.3
  • 54
    • 0034714893 scopus 로고    scopus 로고
    • Interactions between androgen and estrogen receptors and the effects on their transactivational properties
    • 10.1016/S0303-7207(00)00279-3, 11000528
    • Panet-Raymond V, Gottlieb B, Beitel LK, Pinsky L, Trifiro MA. Interactions between androgen and estrogen receptors and the effects on their transactivational properties. Mol Cell Endocrinol 2000, 167:139-150. 10.1016/S0303-7207(00)00279-3, 11000528.
    • (2000) Mol Cell Endocrinol , vol.167 , pp. 139-150
    • Panet-Raymond, V.1    Gottlieb, B.2    Beitel, L.K.3    Pinsky, L.4    Trifiro, M.A.5
  • 55
    • 28544445212 scopus 로고    scopus 로고
    • Steroid receptor regulation of epidermal growth factor signaling through Src in breast and prostate cancer cells: steroid antagonist action
    • 10.1158/0008-5472.CAN-05-0912, 16288052
    • Migliaccio A, Di Domenico M, Castoria G, Nanayakkara M, Lombardi M, de Falco A, Bilancio A, Varricchio L, Ciociola A, Auricchio F. Steroid receptor regulation of epidermal growth factor signaling through Src in breast and prostate cancer cells: steroid antagonist action. Cancer Res 2005, 65:10585-10593. 10.1158/0008-5472.CAN-05-0912, 16288052.
    • (2005) Cancer Res , vol.65 , pp. 10585-10593
    • Migliaccio, A.1    Di Domenico, M.2    Castoria, G.3    Nanayakkara, M.4    Lombardi, M.5    de Falco, A.6    Bilancio, A.7    Varricchio, L.8    Ciociola, A.9    Auricchio, F.10
  • 56
    • 84885210324 scopus 로고    scopus 로고
    • A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509
    • 10.1158/2159-8290.CD-13-0226, 23779130
    • Joseph JD, Lu N, Qian J, Sensintaffar J, Shao G, Brigham D, Moon M, Maneval EC, Chen I, Darimont B, Hager JH. A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509. Cancer Discov 2013, 3:1020-1029. 10.1158/2159-8290.CD-13-0226, 23779130.
    • (2013) Cancer Discov , vol.3 , pp. 1020-1029
    • Joseph, J.D.1    Lu, N.2    Qian, J.3    Sensintaffar, J.4    Shao, G.5    Brigham, D.6    Moon, M.7    Maneval, E.C.8    Chen, I.9    Darimont, B.10    Hager, J.H.11


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