-
1
-
-
84892805731
-
Cancer statistics, 2014
-
Jan-Feb
-
Siegel R, Ma J, Zou Z, et al. Cancer statistics, 2014. CA Cancer J Clin. 2014 Jan-Feb; 64 (1): 9-29.
-
(2014)
CA Cancer J Clin
, vol.64
, Issue.1
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
-
2
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Dec 15
-
Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010 Dec 15; 127 (12): 2893-2917.
-
(2010)
Int J Cancer
, vol.127
, Issue.12
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
-
4
-
-
77950361629
-
Trials with impact on clinical management: First line
-
Dec
-
Bookman MA. Trials with impact on clinical management: first line. Int J Gynecological Cancer. 2009 Dec; 19 (Suppl 2): S55-62.
-
(2009)
Int J Gynecological Cancer
, vol.19
, pp. S55-62
-
-
Bookman, M.A.1
-
5
-
-
77956285631
-
Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer
-
Sep 2
-
Vergote I, Trope CG, Amant F, et al. Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer. N Engl J Med. 2010 Sep 2; 363 (10): 943-953.
-
(2010)
N Engl J Med
, vol.363
, Issue.10
, pp. 943-953
-
-
Vergote, I.1
Trope, C.G.2
Amant, F.3
-
6
-
-
30044438368
-
Intraperitoneal cisplatin and paclitaxel in ovarian cancer
-
Jan 5
-
Armstrong DK, Bundy B, Wenzel L, et al. Intraperitoneal cisplatin and paclitaxel in ovarian cancer. N Engl J Med. 2006 Jan 5; 354 (1): 34-43.
-
(2006)
N Engl J Med
, vol.354
, Issue.1
, pp. 34-43
-
-
Armstrong, D.K.1
Bundy, B.2
Wenzel, L.3
-
7
-
-
70349878651
-
Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer: A phase 3, open-label, randomised controlled trial
-
Oct 17
-
Katsumata N, Yasuda M, Takahashi F, et al. Dose-dense paclitaxel once a week in combination with carboplatin every 3 weeks for advanced ovarian cancer: a phase 3, open-label, randomised controlled trial. Lancet. 2009 Oct 17; 374 (9698): 1331-1338.
-
(2009)
Lancet
, vol.374
, Issue.9698
, pp. 1331-1338
-
-
Katsumata, N.1
Yasuda, M.2
Takahashi, F.3
-
8
-
-
84892508265
-
Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer
-
Feb
-
Colombo PE, Fabbro M, Theillet C, et al. Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer. Crit Rev Oncology-Hematology. 2014 Feb; 89 (2): 207-216.
-
(2014)
Crit Rev Oncology-Hematology
, vol.89
, Issue.2
, pp. 207-216
-
-
Colombo, P.E.1
Fabbro, M.2
Theillet, C.3
-
9
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
Cancer Genome Atlas Research Network. Jun 30
-
Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature. 2011 Jun 30; 474 (7353): 609-615.
-
(2011)
Nature
, vol.474
, Issue.7353
, pp. 609-615
-
-
-
10
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Mar 4
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011 Mar 4; 144 (5): 646-674.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
11
-
-
85026135671
-
Preoperative angiopoietin-2 serum levels: A marker of malignant potential in ovarian neoplasms and poor prognosis in epithelial ovarian cancer
-
Dec
-
Sallinen H, Heikura T, Laidinen S, et al. Preoperative angiopoietin-2 serum levels: a marker of malignant potential in ovarian neoplasms and poor prognosis in epithelial ovarian cancer. Int J Gynecological Cancer. 2010 Dec; 20 (9): 1498-1505.
-
(2010)
Int J Gynecological Cancer
, vol.20
, Issue.9
, pp. 1498-1505
-
-
Sallinen, H.1
Heikura, T.2
Laidinen, S.3
-
12
-
-
3242658330
-
Correlation of serum VEGF levels with clinical stage, therapy efficacy, tumor metastasis and patient survival in ovarian cancer
-
May-Jun
-
Li L, Wang L, Zhang W, et al. Correlation of serum VEGF levels with clinical stage, therapy efficacy, tumor metastasis and patient survival in ovarian cancer. Anticancer Res. 2004 May-Jun; 24 (3b): 1973-1979.
-
(2004)
Anticancer Res
, vol.24
, Issue.3 B
, pp. 1973-1979
-
-
Li, L.1
Wang, L.2
Zhang, W.3
-
13
-
-
84907399835
-
Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer
-
Sallinen H, Heikura T, Koponen J, et al. Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer. BMC Cancer. 2014; 14: 696.
-
(2014)
BMC Cancer
, vol.14
, pp. 696
-
-
Sallinen, H.1
Heikura, T.2
Koponen, J.3
-
14
-
-
33947732977
-
Angiogenesis: An organizing principle for drug discovery?
-
Folkman J. Angiogenesis: an organizing principle for drug discovery? Nat Reviews. Drug Discov. 2007; 6 (4): 273-286.
-
(2007)
Nat Reviews. Drug Discov
, vol.6
, Issue.4
, pp. 273-286
-
-
Folkman, J.1
-
15
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Nov 18
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971 Nov 18; 285 (21): 1182-1186.
-
(1971)
N Engl J Med
, vol.285
, Issue.21
, pp. 1182-1186
-
-
Folkman, J.1
-
16
-
-
84894036626
-
Incorporation of anti-angiogenesis therapy in the management of advanced ovarian carcinoma-mechanistics, review of phase III randomized clinical trials, and regulatory implications
-
Feb
-
Eskander RN, Tewari KS. Incorporation of anti-angiogenesis therapy in the management of advanced ovarian carcinoma-mechanistics, review of phase III randomized clinical trials, and regulatory implications. Gynecol Oncol. 2014 Feb; 132 (2): 496-505.
-
(2014)
Gynecol Oncol
, vol.132
, Issue.2
, pp. 496-505
-
-
Eskander, R.N.1
Tewari, K.S.2
-
17
-
-
0028834106
-
Pathogenesis of ascites tumor growth: Vascular permeability factor, vascular hyperpermeability, and ascites fluid accumulation
-
Jan 15
-
Nagy JA, Masse EM, Herzberg KT, et al. Pathogenesis of ascites tumor growth: vascular permeability factor, vascular hyperpermeability, and ascites fluid accumulation. Cancer Res. 1995 Jan 15; 55 (2): 360-368.
-
(1995)
Cancer Res
, vol.55
, Issue.2
, pp. 360-368
-
-
Nagy, J.A.1
Masse, E.M.2
Herzberg, K.T.3
-
18
-
-
4444324696
-
VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma
-
Sep
-
Chen H, Ye D, Xie X, et al. VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma. Gynecol Oncol. 2004 Sep; 94 (3): 630-635.
-
(2004)
Gynecol Oncol
, vol.94
, Issue.3
, pp. 630-635
-
-
Chen, H.1
Ye, D.2
Xie, X.3
-
19
-
-
84898466302
-
Novel therapies, including enzastaurin, in the treatment of ovarian cancer
-
May
-
Vergote I. Novel therapies, including enzastaurin, in the treatment of ovarian cancer. Expert Opin Investig Drugs. 2014 May; 23 (5): 579-598.
-
(2014)
Expert Opin Investig Drugs
, vol.23
, Issue.5
, pp. 579-598
-
-
Vergote, I.1
-
20
-
-
77951937790
-
Bevacizumab toxicities and their management in ovarian cancer
-
Jun
-
Randall LM, Monk BJ. Bevacizumab toxicities and their management in ovarian cancer. Gynecol Oncol. 2010 Jun; 117 (3): 497-504.
-
(2010)
Gynecol Oncol
, vol.117
, Issue.3
, pp. 497-504
-
-
Randall, L.M.1
Monk, B.J.2
-
21
-
-
84904799144
-
Risk factors for GI adverse events in a phase III randomized trial of bevacizumab in first-line therapy of advanced ovarian cancer: A Gynecologic Oncology Group Study
-
Apr 20
-
Burger RA, Brady MF, Bookman MA, et al., et al. Risk factors for GI adverse events in a phase III randomized trial of bevacizumab in first-line therapy of advanced ovarian cancer: a Gynecologic Oncology Group Study. J Clin Oncol. 2014 Apr 20; 32 (12): 1210-1217.
-
(2014)
J Clin Oncol
, vol.32
, Issue.12
, pp. 1210-1217
-
-
Burger, R.A.1
Brady, M.F.2
Bookman, M.A.3
-
22
-
-
77952314572
-
Collateral damage: Toxic effects of targeted antiangiogenic therapies in ovarian cancer
-
May
-
Stone RL, Sood AK, Coleman RL. Collateral damage: toxic effects of targeted antiangiogenic therapies in ovarian cancer. Lancet Oncol. 2010 May; 11 (5): 465-475.
-
(2010)
Lancet Oncol
, vol.11
, Issue.5
, pp. 465-475
-
-
Stone, R.L.1
Sood, A.K.2
Coleman, R.L.3
-
23
-
-
33845313345
-
The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; A review
-
Dec
-
Eskens FA, Verweij J. The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review. Eur J Cancer. 2006 Dec; 42 (18): 3127-3139.
-
(2006)
Eur J Cancer
, vol.42
, Issue.18
, pp. 3127-3139
-
-
Eskens, F.A.1
Verweij, J.2
-
24
-
-
70449635893
-
Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies
-
Dec
-
Crawford Y, Ferrara N. Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies. Trends Pharmacol Sci. 2009 Dec; 30 (12): 624-630.
-
(2009)
Trends Pharmacol Sci
, vol.30
, Issue.12
, pp. 624-630
-
-
Crawford, Y.1
Ferrara, N.2
-
25
-
-
69349097400
-
Tumor and host-mediated pathways of resistance and disease progression in response to antiangiogenic therapy
-
Aug 15
-
Ebos JM, Lee CR, Kerbel RS. Tumor and host-mediated pathways of resistance and disease progression in response to antiangiogenic therapy. Clin Cancer Res. 2009 Aug 15; 15 (16): 5020-5025.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.16
, pp. 5020-5025
-
-
Ebos, J.M.1
Lee, C.R.2
Kerbel, R.S.3
-
26
-
-
77954890371
-
Targeting the ANGPT-TIE2 pathway in malignancy
-
Huang H, Bhat A, Woodnutt G, et al. Targeting the ANGPT-TIE2 pathway in malignancy. Nat Reviews. Cancer. 2010; 10 (8): 575-585.
-
(2010)
Nat Reviews. Cancer
, vol.10
, Issue.8
, pp. 575-585
-
-
Huang, H.1
Bhat, A.2
Woodnutt, G.3
-
27
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
Dec 27
-
Suri C, Jones PF, Patan S, et al. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell. 1996 Dec 27; 87 (7): 1171-1180.
-
(1996)
Cell
, vol.87
, Issue.7
, pp. 1171-1180
-
-
Suri, C.1
Jones, P.F.2
Patan, S.3
-
28
-
-
0032538385
-
Increased vascularization in mice overexpressing angiopoietin-1
-
Oct 16
-
Suri C, McClain J, Thurston G, et al. Increased vascularization in mice overexpressing angiopoietin-1. Science. 1998 Oct 16; 282 (5388): 468-471.
-
(1998)
Science
, vol.282
, Issue.5388
, pp. 468-471
-
-
Suri, C.1
McClain, J.2
Thurston, G.3
-
29
-
-
33846018408
-
Is angiogenesis an organizing principle in biology and medicine?
-
Jan
-
Folkman J. Is angiogenesis an organizing principle in biology and medicine? J Pediatr Surg. 2007 Jan; 42 (1): 1-11.
-
(2007)
J Pediatr Surg
, vol.42
, Issue.1
, pp. 1-11
-
-
Folkman, J.1
-
30
-
-
33344477298
-
Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling
-
Mar 10
-
Eklund L, Olsen BR. Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling. Exp Cell Res. 2006 Mar 10; 312 (5): 630-641.
-
(2006)
Exp Cell Res
, vol.312
, Issue.5
, pp. 630-641
-
-
Eklund, L.1
Olsen, B.R.2
-
31
-
-
34547103275
-
Angiopoietin: A TIE(d) balance in tumor angiogenesis
-
Jul
-
Shim WS, Ho IA, Wong PE. Angiopoietin: a TIE(d) balance in tumor angiogenesis. Mol Cancer Res: MCR. 2007 Jul; 5 (7): 655-665.
-
(2007)
Mol Cancer Res: MCR
, vol.5
, Issue.7
, pp. 655-665
-
-
Shim, W.S.1
Ho, I.A.2
Wong, P.E.3
-
32
-
-
7944220649
-
Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2
-
Nov
-
Oliner J, Min H, Leal J, et al. Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2. Cancer Cell. 2004 Nov; 6 (5): 507-516.
-
(2004)
Cancer Cell
, vol.6
, Issue.5
, pp. 507-516
-
-
Oliner, J.1
Min, H.2
Leal, J.3
-
33
-
-
79951898433
-
AMG 386: Profile of a novel angiopoietin antagonist in patients with ovarian cancer
-
Feb
-
Robson EJ, Ghatage P. AMG 386: profile of a novel angiopoietin antagonist in patients with ovarian cancer. Expert Opin Investig Drugs. 2011 Feb; 20 (2): 297-304.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, Issue.2
, pp. 297-304
-
-
Robson, E.J.1
Ghatage, P.2
-
34
-
-
84903517779
-
Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): A randomised, multicentre, double-blind, placebo-controlled phase 3 trial
-
Monk BJ, Poveda A, Vergote I, et al. Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial. Lancet Oncol. 2014; 15 (8): 799-808.
-
(2014)
Lancet Oncol
, vol.15
, Issue.8
, pp. 799-808
-
-
Monk, B.J.1
Poveda, A.2
Vergote, I.3
-
35
-
-
84863012011
-
Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer
-
Feb 1
-
Karlan BY, Oza AM, Richardson GE, et al. Randomized, double-blind, placebo-controlled phase II study of AMG 386 combined with weekly paclitaxel in patients with recurrent ovarian cancer. J Clin Oncol. 2012 Feb 1; 30 (4): 362-371.
-
(2012)
J Clin Oncol
, vol.30
, Issue.4
, pp. 362-371
-
-
Karlan, B.Y.1
Oza, A.M.2
Richardson, G.E.3
-
36
-
-
85027945168
-
A phase 1b, open-label study of trebananib in combination with paclitaxel and carboplatin in patients with ovarian cancer receiving interval or primary debulking surgery
-
Sep
-
Vergote I, Oaknin A, Baurain JF, et al. A phase 1b, open-label study of trebananib in combination with paclitaxel and carboplatin in patients with ovarian cancer receiving interval or primary debulking surgery. Eur J Cancer. 2014 Sep; 50 (14): 2408-2416.
-
(2014)
Eur J Cancer
, vol.50
, Issue.14
, pp. 2408-2416
-
-
Vergote, I.1
Oaknin, A.2
Baurain, J.F.3
-
37
-
-
84908022446
-
A phase 1b study of trebananib in combination with pegylated liposomal doxorubicin or topotecan in women with recurrent platinum-resistant or partially platinum-sensitive ovarian cancer
-
Oct
-
Vergote I, Schilder RJ, Pippitt CH Jr, et al. A phase 1b study of trebananib in combination with pegylated liposomal doxorubicin or topotecan in women with recurrent platinum-resistant or partially platinum-sensitive ovarian cancer. Gynecol Oncol. 2014 Oct; 135 (1): 25-33.
-
(2014)
Gynecol Oncol
, vol.135
, Issue.1
, pp. 25-33
-
-
Vergote, I.1
Schilder, R.J.2
Pippitt, C.H.3
-
38
-
-
84882453744
-
Incidence and management of edema associated with trebananib (AMG 386)
-
Sep
-
Monk BJ, Minion L, Lambrechts S, et al. Incidence and management of edema associated with trebananib (AMG 386). Gynecol Oncol. 2013 Sep; 130 (3): 636-641.
-
(2013)
Gynecol Oncol
, vol.130
, Issue.3
, pp. 636-641
-
-
Monk, B.J.1
Minion, L.2
Lambrechts, S.3
-
39
-
-
13144254247
-
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
-
Jul 21
-
Lin P, Buxton JA, Acheson A, et al. Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. Proc Natl Acad Sci U S A. 1998 Jul 21; 95 (15): 8829-8834.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.15
, pp. 8829-8834
-
-
Lin, P.1
Buxton, J.A.2
Acheson, A.3
-
40
-
-
0030726988
-
Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth
-
Oct 15
-
Lin P, Polverini P, Dewhirst M, et al. Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth. J Clin Invest. 1997 Oct 15; 100 (8): 2072-2078.
-
(1997)
J Clin Invest
, vol.100
, Issue.8
, pp. 2072-2078
-
-
Lin, P.1
Polverini, P.2
Dewhirst, M.3
-
41
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
Jul 4
-
Maisonpierre PC, Suri C, Jones PF, et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science. 1997 Jul 4; 277 (5322): 55-60.
-
(1997)
Science
, vol.277
, Issue.5322
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
-
42
-
-
73649112748
-
Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels
-
Nov
-
Falcon BL, Hashizume H, Koumoutsakos P, et al. Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels. Am J Pathol. 2009 Nov; 175 (5): 2159-2170.
-
(2009)
Am J Pathol
, vol.175
, Issue.5
, pp. 2159-2170
-
-
Falcon, B.L.1
Hashizume, H.2
Koumoutsakos, P.3
-
43
-
-
77958042477
-
Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: Implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody
-
Oct
-
Coxon A, Bready J, Min H, et al. Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody. Mol Cancer Ther. 2010 Oct; 9 (10): 2641-2651.
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.10
, pp. 2641-2651
-
-
Coxon, A.1
Bready, J.2
Min, H.3
-
44
-
-
36849056497
-
Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
-
Nov 20
-
Cannistra SA, Matulonis UA, Penson RT, et al. Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer. J Clin Oncol. 2007 Nov 20; 25 (33): 5180-5186.
-
(2007)
J Clin Oncol
, vol.25
, Issue.33
, pp. 5180-5186
-
-
Cannistra, S.A.1
Matulonis, U.A.2
Penson, R.T.3
-
45
-
-
84858200516
-
Antiangiogenic agents in combination with chemotherapy for the treatment of epithelial ovarian cancer
-
Mar
-
Teoh D, Secord AA. Antiangiogenic agents in combination with chemotherapy for the treatment of epithelial ovarian cancer. Int J Gynecological Cancer. 2012 Mar; 22 (3): 348-359.
-
(2012)
Int J Gynecological Cancer
, vol.22
, Issue.3
, pp. 348-359
-
-
Teoh, D.1
Secord, A.A.2
-
46
-
-
84862275233
-
Exposure-response relationship of AMG 386 in combination with weekly paclitaxel in recurrent ovarian cancer and its implication for dose selection
-
May
-
Lu JF, Rasmussen E, Karlan BY, et al. Exposure-response relationship of AMG 386 in combination with weekly paclitaxel in recurrent ovarian cancer and its implication for dose selection. Cancer Chemother Pharmacol. 2012 May; 69 (5): 1135-1144.
-
(2012)
Cancer Chemother Pharmacol
, vol.69
, Issue.5
, pp. 1135-1144
-
-
Lu, J.F.1
Rasmussen, E.2
Karlan, B.Y.3
-
47
-
-
70249114453
-
Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors
-
Jul 20
-
Herbst RS, Hong D, Chap L, et al. Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors. J Clin Oncol. 2009 Jul 20; 27 (21): 3557-3565.
-
(2009)
J Clin Oncol
, vol.27
, Issue.21
, pp. 3557-3565
-
-
Herbst, R.S.1
Hong, D.2
Chap, L.3
-
48
-
-
84872326846
-
Phase 1 study of trebananib (AMG 386), an angiogenesis targeting angiopoietin-1/2 antagonist, in Japanese patients with advanced solid tumors
-
Jan
-
Doi T, Ohtsu A, Fuse N, et al. Phase 1 study of trebananib (AMG 386), an angiogenesis targeting angiopoietin-1/2 antagonist, in Japanese patients with advanced solid tumors. Cancer Chemother Pharmacol. 2013 Jan; 71 (1): 227-235.
-
(2013)
Cancer Chemother Pharmacol
, vol.71
, Issue.1
, pp. 227-235
-
-
Doi, T.1
Ohtsu, A.2
Fuse, N.3
-
49
-
-
36849019301
-
Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group Study
-
Nov 20
-
Burger RA, Sill MW, Monk BJ, et al. Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study. J Clin Oncol. 2007 Nov 20; 25 (33): 5165-5171.
-
(2007)
J Clin Oncol
, vol.25
, Issue.33
, pp. 5165-5171
-
-
Burger, R.A.1
Sill, M.W.2
Monk, B.J.3
-
50
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jan 7
-
Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science. 2005 Jan 7; 307 (5706): 58-62.
-
(2005)
Science
, vol.307
, Issue.5706
, pp. 58-62
-
-
Jain, R.K.1
-
51
-
-
77953097101
-
Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumors
-
Jun 1
-
Mita AC, Takimoto CH, Mita M, et al. Phase 1 study of AMG 386, a selective angiopoietin 1/2-neutralizing peptibody, in combination with chemotherapy in adults with advanced solid tumors. Clin Cancer Res. 2010 Jun 1; 16 (11): 3044-3056.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.11
, pp. 3044-3056
-
-
Mita, A.C.1
Takimoto, C.H.2
Mita, M.3
-
52
-
-
79951579430
-
A phase II study of two topotecan regimens evaluated in recurrent platinum-sensitive ovarian, fallopian tube or primary peritoneal cancer: A Gynecologic Oncology Group Study (GOG 146Q)
-
Mar
-
Herzog TJ, Sill MW, Walker JL, et al. A phase II study of two topotecan regimens evaluated in recurrent platinum-sensitive ovarian, fallopian tube or primary peritoneal cancer: a Gynecologic Oncology Group Study (GOG 146Q). Gynecol Oncol. 2011 Mar; 120 (3): 454-458.
-
(2011)
Gynecol Oncol
, vol.120
, Issue.3
, pp. 454-458
-
-
Herzog, T.J.1
Sill, M.W.2
Walker, J.L.3
-
53
-
-
0035165412
-
Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: Analysis of toxicities and predictors of outcome
-
Jan 1
-
Safra T, Groshen S, Jeffers S, et al. Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: analysis of toxicities and predictors of outcome. Cancer. 2001 Jan 1; 91 (1): 90-100.
-
(2001)
Cancer
, vol.91
, Issue.1
, pp. 90-100
-
-
Safra, T.1
Groshen, S.2
Jeffers, S.3
-
54
-
-
84856693516
-
Moving beyond anti-vascular endothelial growth factor therapy in ovarian cancer
-
Feb 1
-
Sood AK, Coleman RL, Ellis LM. Moving beyond anti-vascular endothelial growth factor therapy in ovarian cancer. J Clin Oncol. 2012 Feb 1; 30 (4): 345-347.
-
(2012)
J Clin Oncol
, vol.30
, Issue.4
, pp. 345-347
-
-
Sood, A.K.1
Coleman, R.L.2
Ellis, L.M.3
-
55
-
-
84856331988
-
Weekly paclitaxel as a single agent or in combination with carboplatin or weekly topotecan in patients with resistant ovarian cancer: The CARTAXHY randomized phase II trial from Groupe dInvestigateurs Nationaux pour lEtude des Cancers Ovariens (GINECO)
-
Feb
-
Lortholary A, Largillier R, Weber B, et al. Weekly paclitaxel as a single agent or in combination with carboplatin or weekly topotecan in patients with resistant ovarian cancer: the CARTAXHY randomized phase II trial from Groupe dInvestigateurs Nationaux pour lEtude des Cancers Ovariens (GINECO). Ann Oncol. 2012 Feb; 23 (2): 346-352.
-
(2012)
Ann Oncol
, vol.23
, Issue.2
, pp. 346-352
-
-
Lortholary, A.1
Largillier, R.2
Weber, B.3
-
56
-
-
77957564567
-
Weekly paclitaxel in the treatment of recurrent ovarian cancer
-
Oct
-
Baird RD, Tan DS, Kaye SB. Weekly paclitaxel in the treatment of recurrent ovarian cancer. Nat Rev Clin Oncol. 2010 Oct; 7 (10): 575-582.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, Issue.10
, pp. 575-582
-
-
Baird, R.D.1
Tan, D.S.2
Kaye, S.B.3
-
57
-
-
71549143528
-
Detecting an overall survival benefit that is derived from progression-free survival
-
Dec 2
-
Broglio KR, Berry DA. Detecting an overall survival benefit that is derived from progression-free survival. J Natl Cancer Inst. 2009 Dec 2; 101 (23): 1642-1649.
-
(2009)
J Natl Cancer Inst
, vol.101
, Issue.23
, pp. 1642-1649
-
-
Broglio, K.R.1
Berry, D.A.2
-
58
-
-
79960592856
-
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
-
Jul 5
-
Schaefer W, Regula JT, Bahner M, et al. Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies. Proc Natl Acad Sci U S A. 2011 Jul 5; 108 (27): 11187-11192.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.27
, pp. 11187-11192
-
-
Schaefer, W.1
Regula, J.T.2
Bahner, M.3
-
59
-
-
84875998274
-
Markers of response for the antiangiogenic agent bevacizumab
-
Mar 20
-
Lambrechts D, Lenz HJ, De Haas S, et al. Markers of response for the antiangiogenic agent bevacizumab. J Clin Oncol. 2013 Mar 20; 31 (9): 1219-1230.
-
(2013)
J Clin Oncol
, vol.31
, Issue.9
, pp. 1219-1230
-
-
Lambrechts, D.1
Lenz, H.J.2
De Haas, S.3
-
60
-
-
84879850441
-
Identification and analysis of in vivo VEGF downstream markers link VEGF pathway activity with efficacy of anti-VEGF therapies
-
Jul 1
-
Brauer MJ, Zhuang G, Schmidt M, et al. Identification and analysis of in vivo VEGF downstream markers link VEGF pathway activity with efficacy of anti-VEGF therapies. Clin Cancer Res. 2013 Jul 1; 19 (13): 3681-3692.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.13
, pp. 3681-3692
-
-
Brauer, M.J.1
Zhuang, G.2
Schmidt, M.3
-
61
-
-
84878877091
-
Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: Systems biology predictions
-
Jun 5
-
Finley SD, Popel AS. Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions. J Natl Cancer Inst. 2013 Jun 5; 105 (11): 802-811.
-
(2013)
J Natl Cancer Inst
, vol.105
, Issue.11
, pp. 802-811
-
-
Finley, S.D.1
Popel, A.S.2
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