Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex

Oncogene

Volumn 35, Issue 29, 2016, Pages 3760-3770

  Garibaldi, F ^a   Falcone, E ^a   Trisciuoglio, D ^a   Colombo, T ^b,c   Lisek, K ^d,e   Walerych, D ^d   Del Sal, G ^d,e   Paci, P ^b,c   Bossi, G ^a   Piaggio, G ^a   Gurtner, A ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b CNR   (Italy)

^c SysBio Centre for Systems Biology   (Italy)

^d AREA Science Park   (Italy)

^e UNIVERSITY OF TRIESTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DICER; DOXORUBICIN; LENTIVIRUS VECTOR; MICRORNA; MICRORNA 105; MICRORNA 218; MICRORNA 517A; MICRORNA 519A; PROTEIN P53; PROTEIN P72; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; UVOMORULIN; DDX17 PROTEIN, HUMAN; DEAD BOX PROTEIN; PROTEIN BINDING;

ARTICLE; BIOGENESIS; CANCER CELL; CELL COUNT; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL GROWTH; CELL MIGRATION; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; COLONY FORMING UNIT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ECTOPIC EXPRESSION; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; MISSENSE MUTATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; TRANSIENT EXPRESSION; UPREGULATION; APOPTOSIS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; HCT 116 CELL LINE; HEK293 CELL LINE; HT-29 CELL LINE; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MUTATION; NEOPLASM; PATHOLOGY; RNA INTERFERENCE; RNA PROCESSING; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DEAD-BOX RNA HELICASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HEK293 CELLS; HT29 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICRORNAS; MUTATION; NEOPLASMS; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA PROCESSING, POST-TRANSCRIPTIONAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84961390703     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2016.51     Document Type: Article

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