메뉴 건너뛰기




Volumn 381, Issue 1-2, 2013, Pages 61-68

P53siRNA therapy reduces cell proliferation, migration and induces apoptosis in triple negative breast cancer cells

Author keywords

Apoptosis; Cell proliferation; Migration; P53siRNA; Triple negative breast cells

Indexed keywords

PROTEIN BCL 2; PROTEIN P53; SMALL INTERFERING RNA;

EID: 84882639080     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1688-5     Document Type: Article
Times cited : (54)

References (32)
  • 1
    • 77953406697 scopus 로고    scopus 로고
    • Targeting p53 for novel anticancer therapy
    • Wang Z, Sun Y (2010) Targeting p53 for novel anticancer therapy. Transl Oncol 3(1):1-12
    • (2010) Transl Oncol , vol.3 , Issue.1 , pp. 1-12
    • Wang, Z.1    Sun, Y.2
  • 2
    • 0024382760 scopus 로고
    • The p53 proto-oncogene can act as a suppressor of transformation
    • Finlay CA, Hinds PW, Levine AJ (1989) The p53 proto-oncogene can act as a suppressor of transformation. Cell 57(7):1083-1093
    • (1989) Cell , vol.57 , Issue.7 , pp. 1083-1093
    • Finlay, C.A.1    Hinds, P.W.2    Levine, A.J.3
  • 3
    • 79955034094 scopus 로고    scopus 로고
    • Triterpe-noids as potential agents for the chemoprevention and therapy of breast cancer
    • Bishayee A, Ahmed S, Brankov N, Perloff M (2011) Triterpe-noids as potential agents for the chemoprevention and therapy of breast cancer. Front Biosci 16:980-996
    • (2011) Front Biosci , vol.16 , pp. 980-996
    • Bishayee, A.1    Ahmed, S.2    Brankov, N.3    Perloff, M.4
  • 5
    • 79952767541 scopus 로고    scopus 로고
    • Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells
    • Liu Y-Y, Patwardhan G, Bhinge K, Gupta V, Gu X, Jazwinski M (2011) Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells. Cancer Res 71(6):2276-2285
    • (2011) Cancer Res , vol.71 , Issue.6 , pp. 2276-2285
    • Liu, Y.-Y.1    Patwardhan, G.2    Bhinge, K.3    Gupta, V.4    Gu, X.5    Jazwinski, M.6
  • 6
    • 0035890360 scopus 로고    scopus 로고
    • Increased p53 mutation frequency during tumor progres-sion-results from a breast cancer cohort
    • Norberg T, Klaar S, Karf G, Nordgren H, Holmberg L, Bergh J (2001) Increased p53 mutation frequency during tumor progres-sion-results from a breast cancer cohort. Cancer Res 61:8317-8321
    • (2001) Cancer Res , vol.61 , pp. 8317-8321
    • Norberg, T.1    Klaar, S.2    Karf, G.3    Nordgren, H.4    Holmberg, L.5    Bergh, J.6
  • 7
    • 0034671945 scopus 로고    scopus 로고
    • Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome
    • Sigal A, Rotter V (2000) Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res 60:6788-6793
    • (2000) Cancer Res , vol.60 , pp. 6788-6793
    • Sigal, A.1    Rotter, V.2
  • 8
    • 34247899190 scopus 로고    scopus 로고
    • Cancer-derived p53 mutants suppress p53-target gene expression-potential mechanism for gain of function of mutant p53
    • Vikhanskaya F, Lee K, Mazzoletti M, Broggini M, Sabapathy K (2007) Cancer-derived p53 mutants suppress p53-target gene expression-potential mechanism for gain of function of mutant p53. Nucleic Acids Res 35(6):2093-2104
    • (2007) Nucleic Acids Res , vol.35 , Issue.6 , pp. 2093-2104
    • Vikhanskaya, F.1    Lee, K.2    Mazzoletti, M.3    Broggini, M.4    Sabapathy, K.5
  • 9
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • Kim DH, Rossi JJ (2007) Strategies for silencing human disease using RNA interference. Nat Rev Genet 8:173-184
    • (2007) Nat Rev Genet , vol.8 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 10
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp TR, Bernards R, Agami R (2002) Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2:243-247
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 11
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • Kim DH, Rossi JJ (2007) Strategies for silencing human disease using RNA interference. Nat Rev Genet 8:173-184
    • (2007) Nat Rev Genet , vol.8 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 12
    • 11444265150 scopus 로고    scopus 로고
    • Interfering with cancer: A brief outline of advances in RNA interference in oncology
    • Rye PD, Stigbrand T (2004) Interfering with cancer: A brief outline of advances in RNA interference in oncology. Tumor Biology 25:5-6
    • (2004) Tumor Biology , vol.25 , pp. 5-6
    • Rye, P.D.1    Stigbrand, T.2
  • 17
    • 77954378366 scopus 로고    scopus 로고
    • MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
    • Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, Xiong W, Li G, Lu J, Fodstad O, Riker AI, Tan M (2010) MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression. J Biol Chem 285(28):21496-21507
    • (2010) J Biol Chem , vol.285 , Issue.28 , pp. 21496-21507
    • Zhou, M.1    Liu, Z.2    Zhao, Y.3    Ding, Y.4    Liu, H.5    Xi, Y.6    Xiong, W.7    Li, G.8    Lu, J.9    Fodstad, O.10    Riker, A.I.11    Tan, M.12
  • 18
    • 78049290432 scopus 로고    scopus 로고
    • Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cellmediated killing
    • Scott GB, Bowles PA, Wilson EB, Meade JL, Low BC, Davison A, Davison A, Blair GE, Cook GP (2010) Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cellmediated killing. Biochem J 431:423-431
    • (2010) Biochem J , vol.431 , pp. 423-431
    • Scott, G.B.1    Bowles, P.A.2    Wilson, E.B.3    Meade, J.L.4    Low, B.C.5    Davison, A.6    Davison, A.7    Blair, G.E.8    Cook, G.P.9
  • 19
    • 67650076845 scopus 로고    scopus 로고
    • Mcl-1 integrates the opposing actions of signaling pathways that mediate survival and apoptosis
    • Morel C, Carlson SM, White FM, Davis RJ (2009) Mcl-1 integrates the opposing actions of signaling pathways that mediate survival and apoptosis. Mol Cell Biol 29(14):3845-3852
    • (2009) Mol Cell Biol , vol.29 , Issue.14 , pp. 3845-3852
    • Morel, C.1    Carlson, S.M.2    White, F.M.3    Davis, R.J.4
  • 20
    • 79953750869 scopus 로고    scopus 로고
    • Apoptotic cell signaling in cancer progression and therapy
    • Plati J, Bucur O, Khosravi-Far R (2011) Apoptotic cell signaling in cancer progression and therapy. Integr Biol (Camb) 3(4):279-296
    • (2011) Integr Biol (Camb) , vol.3 , Issue.4 , pp. 279-296
    • Plati, J.1    Bucur, O.2    Khosravi-Far, R.3
  • 23
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A review of programmed cell death
    • Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35(4):495-516
    • (2007) Toxicol Pathol , vol.35 , Issue.4 , pp. 495-516
    • Elmore, S.1
  • 24
    • 79956113945 scopus 로고    scopus 로고
    • Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer
    • Booy EP, Henson ES, Gibson SB (2011) Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer. Oncog 30:2367-2378
    • (2011) Oncog , vol.30 , pp. 2367-2378
    • Booy, E.P.1    Henson, E.S.2    Gibson, S.B.3
  • 25
    • 36349017908 scopus 로고    scopus 로고
    • Wang Anoikis HG. Initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis
    • Woods NT, Yamaguchi H, Lee FY, Bhalla KN (2007) Wang Anoikis HG. initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis. Cancer Res 67:10744
    • (2007) Cancer Res , vol.67 , pp. 10744
    • Woods, N.T.1    Yamaguchi, H.2    Lee, F.Y.3    Bhalla, K.N.4
  • 26
    • 0042701989 scopus 로고    scopus 로고
    • BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis
    • Qin W, Hu J, Guo M, Xu J, Li J, Yao G et al (2003) BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis. Biochem Biophys Res Commun 308:379-385
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 379-385
    • Qin, W.1    Hu, J.2    Guo, M.3    Xu, J.4    Li, J.5    Yao, G.6
  • 27
    • 61949109023 scopus 로고    scopus 로고
    • A functional and regulatory network associated with PIP expression in human breast cancer
    • Debily MA, Marhomy SE, Boulanger V, Eveno E, Mariage-Samson R, Camarca A et al (2009) A functional and regulatory network associated with PIP expression in human breast cancer. PLoS One 4(3):4696
    • (2009) PLoS One , vol.4 , Issue.3 , pp. 4696
    • Debily, M.A.1    Marhomy, S.E.2    Boulanger, V.3    Eveno, E.4    Mariage-Samson, R.5    Camarca, A.6
  • 28
    • 79959438247 scopus 로고    scopus 로고
    • Effector caspases and leukemia
    • doi:10.1155/2011/738301
    • Lu Y, Chen GQ (2011) Effector caspases and leukemia. Int J of Cell Biol. doi:10.1155/2011/738301
    • (2011) Int J of Cell Biol
    • Lu, Y.1    Chen, G.Q.2
  • 29
    • 84856262667 scopus 로고    scopus 로고
    • C-Rel deficiency increases caspase-4 expression and leads to ER stress and necrosis in EBV-transformed cells
    • Valentín-Acevedo A, Sinquett FL, Covey LR (2011) c-Rel deficiency increases caspase-4 expression and leads to ER stress and necrosis in EBV-transformed cells. PLoS One 6(10):25467
    • (2011) PLoS One , vol.6 , Issue.10 , pp. 25467
    • Valentín-Acevedo, A.1    Sinquett, F.L.2    Covey, L.R.3
  • 30
    • 0033748105 scopus 로고    scopus 로고
    • Treatment with the pure antiestrogen faslodex (ICI 182780) induces tumor necrosis factor receptor 1 (TNFR1) expression in MCF-7 breast cancer cells
    • Smolnikar K, Löffek S, Schulz T, Michna H, Diel P (2000) Treatment with the pure antiestrogen faslodex (ICI 182780) induces tumor necrosis factor receptor 1 (TNFR1) expression in MCF-7 breast cancer cells. Breast Cancer Res Treat 63(3):249-259
    • (2000) Breast Cancer Res Treat , vol.63 , Issue.3 , pp. 249-259
    • Smolnikar, K.1    Löffek, S.2    Schulz, T.3    Michna, H.4    Diel, P.5
  • 31
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy Bcl-2 apoptotic switch in cancer
    • Adams JM, Cory S (2007) The Bcl-2 apoptotic switch in cancer development and therapy Bcl-2 apoptotic switch in cancer. Oncog 26:1324-1337
    • (2007) Oncog , vol.26 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 32
    • 26444546442 scopus 로고    scopus 로고
    • An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
    • Miller LD, Smeds J, George J, Vega VB, Vergara L, Ploner A (2005) An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. PNAS 2(38):13550-13555
    • (2005) PNAS , vol.2 , Issue.38 , pp. 13550-13555
    • Miller, L.D.1    Smeds, J.2    George, J.3    Vega, V.B.4    Vergara, L.5    Ploner, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.