Mutant p53-induced up-regulation of mitogen-activated protein kinase kinase 3 contributes to gain of function

Journal of Biological Chemistry

Volumn 285, Issue 19, 2010, Pages 14160-14169

  Gurtner, Aymone ^a   Starace, Giuseppe ^b   Norelli, Giuseppe ^a   Piaggio, Giulia ^a   Sacchi, Ada ^a   Bossi, Gianluca ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; COFACTORS; ECTOPIC EXPRESSIONS; GAIN-OF FUNCTION; HUMAN TUMOR CELLS; MITOGEN-ACTIVATED PROTEIN KINASE KINASE; P53 MUTANTS; P53 PROTEIN; PROTEIN LEVEL; TRANSCRIPTIONAL TARGETS; TUMOR PROGRESSIONS; UP-REGULATION;

GENE EXPRESSION; TUMORS;

PROTEINS;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; NUCLEAR FACTOR Y; PROTEIN P53;

ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; GENE ACTIVATION; HUMAN; HUMAN CELL; MUTANT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN TARGETING; REGULATORY MECHANISM; TUMOR CELL; UPREGULATION;

BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE KINASE 3; MUTANT PROTEINS; MUTATION; NEOPLASMS; NF-KAPPA B; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 77951982002     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.094813     Document Type: Article

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