HER2 Transmembrane Domain Dimerization Coupled with Self-Association of Membrane-Embedded Cytoplasmic Juxtamembrane Regions

Journal of Molecular Biology

Volumn 428, Issue 1, 2016, Pages 52-61

  Bragin, Pavel E ^a,b   Mineev, Konstantin S ^a   Bocharova, Olga V ^a   Volynsky, Pavel E ^a   Bocharov, Eduard V ^a   Arseniev, Alexander S ^a,c  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c MOSCOW INSTITUTE OF PHYSICS AND TECHNOLOGY   (Russian Federation)

Author keywords

alternative dimerization of transmembrane and; coupled protein protein and protein lipid interactions; ; cytoplasmic juxtamembrane domains; ; environment; heteronuclear NMR using membrane mimicking micellar; inactive and active states of HER2 receptor tyrosine; kinase; ; structure function relationship;

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN;

ARTICLE; CYTOPLASM; DIMERIZATION; ENZYME ACTIVITY; ENZYME CONFORMATION; MICELLE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN STRUCTURE; BIOLOGICAL MODEL; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION;

CELL MEMBRANE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN MULTIMERIZATION; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION;

EID: 84961299369     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2015.11.007     Document Type: Article

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