Insight into alteration of gut microbiota in Clostridium difficile infection and asymptomatic C. difficile colonization

Anaerobe

Volumn 34, Issue , 2015, Pages 1-7

  Zhang, Lihua ^a   Dong, Danfeng ^a   Jiang, Cen ^a   Li, Zhen ^a   Wang, Xuefeng ^a   Peng, Yibing ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Asymptomatic carrier; Clostridium difficile infection; Gut microbiota

Indexed keywords

RNA 16S; BACTERIAL DNA; RIBOSOME DNA;

16S RRNA GENE; ADULT; ARTICLE; BACTERIAL COLONIZATION; BACTEROIDETES; CLINICAL ARTICLE; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; DISEASE CARRIER; FECES ANALYSIS; FIRMICUTES; GENETIC VARIABILITY; HUMAN; INTESTINE FLORA; MICROBIAL COMMUNITY; MICROBIOME; NONHUMAN; POPULATION ABUNDANCE; PRIORITY JOURNAL; PROTEOBACTERIA; PYROSEQUENCING; VIRUS GENE; AGED; CHEMISTRY; CLOSTRIDIUM INFECTION; DNA SEQUENCE; FECES; FEMALE; GENETICS; GROWTH, DEVELOPMENT AND AGING; HETEROZYGOTE; MALE; MICROBIOLOGY; MICROFLORA; MIDDLE AGED; MOLECULAR GENETICS; PEPTOCLOSTRIDIUM DIFFICILE; VERY ELDERLY;

BACTEROIDETES; CLOSTRIDIUM DIFFICILE; FIRMICUTES; PROTEOBACTERIA;

ADULT; AGED; AGED, 80 AND OVER; CARRIER STATE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; DNA, BACTERIAL; DNA, RIBOSOMAL; FECES; FEMALE; GASTROINTESTINAL MICROBIOME; HUMANS; MALE; MICROBIOTA; MIDDLE AGED; MOLECULAR SEQUENCE DATA; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA;

EID: 84961291897     PISSN: 10759964     EISSN: 10958274     Source Type: Journal    
DOI: 10.1016/j.anaerobe.2015.03.008     Document Type: Article

References (32)

1. Ananthakrishnan A.N. Clostridium difficile infection: epidemiology, risk factors and management. Nat. Rev. Gastroenterol. Hepatol. 2011, 8:17-26.
2. O'Connor J.R., Johnson S., Gerding D.N. Clostridium difficile infection caused by the epidemic BI/NAP1/027 strain. Gastroenterology 2009, 136:1913-1924.
3. Kim Y.S., Han D.S., Kim Y.H., Kim W.H., Kim J.S., Kim H.S., et al. Incidence and clinical features of Clostridium difficile infection in Korea: a nationwide study. Epidemiol. Infect. 2013, 141:189-194.
4. Lim P.L., Barkham T.M.S., Ling L.M., Dimatatac F., Alfred T., Ang B. Increasing incidence of Clostridium difficile-associated disease, Singapore. Emerg. Infect. Dis. 2008, 14:1487-1489.
5. Galdys A.L., Nelson J.S., Shutt K.A., Schlackman J.L., Pakstis D.L., Pasculle A.W., et al. Prevalence and duration of asymptomatic Clostridium difficile carriage among healthy subjects in Pittsburgh, Pennsylvania. J.Clin. Microbiol. 2014, 52:2406-2409.
6. Furuichi M., Imajo E., Sato Y., Tanno S., Kawada M., Sato S. Characteristics of Clostridium difficile colonization in Japanese children. J.Infect. Chemother. 2014, 20:307-311.
7. Kelly C.P., LaMont J.T. Clostridium difficile-more difficult than ever. N.Engl. J. Med. 2008, 359:1932-1940.
8. Di Bella S., Drapeau C., Garcia-Almodovar E., Petrosillo N. Fecal microbiota transplantation: the state of the art. Infect. Dis. Rep. 2013, 5:e13.
9. Hamilton M.J., Weingarden A.R., Unno T., Khoruts A., Sadowsky M.J. High-throughput DNA sequence analysis reveals stable engraftment of gut microbiota following transplantation of previously frozen fecal bacteria. Gut Microbes 2013, 4:125-135.
10. Broecker F., Kube M., Klumpp J., Schuppler M., Biedermann L., Hecht J., et al. Analysis of the intestinal microbiome of a recovered Clostridium difficile patient after fecal transplantation. Digestion 2013, 88:243-251.
11. Kassam Z., Lee C.H., Yuan Y., Hunt R.H. Fecal microbiota transplantation for Clostridium difficile infection: systematic review and meta-analysis. Am. J. Gastroenterol. 2013, 108:500-508.
12. Koenigsknecht M.J., Young V.B. Faecal microbiota transplantation for the treatment of recurrent Clostridium difficile infection: current promise and future needs. Curr. Opin. Gastroenterol. 2013, 29:628-632.
13. Pathak R., Enuh H.A., Patel A., Wickremesinghe P. Treatment of relapsing Clostridium difficile infection using fecal microbiota transplantation. Clin. Exp. Gastroenterol. 2013, 7:1-6.
14. Chang J.Y., Antonopoulos D.A., Kalra A., Tonelli A., Khalife W.T., Schmidt T.M., et al. Decreased diversity of the fecal microbiome in recurrent Clostridium difficile-associated diarrhea. J.Infect. Dis. 2008, 197:435-438.
15. Flores R., Shi J., Gail M.H., Gajer P., Ravel J., Goedert J.J. Assessment of the human fecal microbiota: II. Reproducibility and associations of 16S rRNA pyrosequences. Eur. J. Clin. Invest. 2012, 42:855-863.
16. Schloss P.D., Westcott S.L., Ryabin T., Hall J.R., Hartmann M., Hollister E.B., et al. Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities. Appl. Environ. Microbiol. 2009, 75:7537-7541.
17. Allegretti J.R., Hamilton M.J. Restoring the gut microbiome for the treatment of inflammatory bowel diseases. World J. Gastroenterol. 2014, 20:3468-3474.
18. Million M., Lagier J.C., Yahav D., Paul M. Gut bacterial microbiota and obesity. Clin. Microbiol. Infect. 2013, 19:305-313.
19. Rubin T.A., Gessert C.E., Aas J., Bakken J.S. Fecal microbiome transplantation for recurrent Clostridium difficile infection: report on a case series. Anaerobe 2013, 19:22-26.
20. Manges A.R., Labbe A., Loo V.G., Atherton J.K., Behr M.A., Masson L., et al. Comparative metagenomic study of alterations to the intestinal microbiota and risk of nosocomial Clostridium difficile-associated disease. J.Infect. Dis. 2010, 202:1877-1884.
21. Shahinas D., Silverman M., Sittler T., Chiu C., Kim P., Allen-Vercoe E., et al. Toward an understanding of changes in diversity associated with fecal microbiome transplantation based on 16S rRNA gene deep sequencing. MBio 2012, 3.
22. Song Y., Garg S., Girotra M., Maddox C., von Rosenvinge E.C., Dutta A., et al. Microbiota dynamics in patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection. PLoS One 2013, 8:e81330.
23. Skraban J., Dzeroski S., Zenko B., Mongus D., Gangl S., Rupnik M. Gut microbiota patterns associated with colonization of different Clostridium difficile ribotypes. PLoS One 2013, 8:e58005.
24. Seekatz A.M., Aas J., Gessert C.E., Rubin T.A., Saman D.M., Bakken J.S., et al. Recovery of the gut microbiome following fecal microbiota transplantation. MBio 2014, 5. e00893-14.
25. Antharam V.C., Li E.C., Ishmael A., Sharma A., Mai V., Rand K.H., et al. Intestinal dysbiosis and depletion of butyrogenic bacteria in Clostridium difficile infection and nosocomial diarrhea. J.Clin. Microbiol. 2013, 51:2884-2892.
26. Bibbo S., Lopetuso L.R., Ianiro G., Di Rienzo T., Gasbarrini A., Cammarota G. Role of microbiota and innate immunity in recurrent infection. J.Immunol. Res. 2014, 2014:462740.
27. Wong J.M., de Souza R., Kendall C.W., Emam A., Jenkins D.J. Colonic health: fermentation and short chain fatty acids. J.Clin. Gastroenterol. 2006, 40:235-243.
28. Guilloteau P., Martin L., Eeckhaut V., Ducatelle R., Zabielski R., Van Immerseel F. From the gut to the peripheral tissues: the multiple effects of butyrate. Nutr. Res. Rev. 2010, 23:366-384.
29. Cook S.I., Sellin J.H. Review article: short chain fatty acids in health and disease. Aliment. Pharmacol. Ther. 1998, 12:499-507.
30. Hamer H.M., Jonkers D., Venema K., Vanhoutvin S., Troost F.J., Brummer R.J. Review article: the role of butyrate on colonic function. Aliment. Pharmacol. Ther. 2008, 27:104-119.
31. Buffie C.G., Bucci V., Stein R.R., McKenney P.T., Ling L., Gobourne A., et al. Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile. Nature 2015, 517(7533):205-208. 10.1038/nature13828.
32. Theriot C.M., Young V.B. Microbial and metabolic interactions between the gastrointestinal tract and Clostridium difficile infection. Gut Microbes 2014, 5:86-95.