Herb-drug interaction between an anti-HIV Chinese herbal SH formula and atazanavir in vitro and in vivo

Journal of Ethnopharmacology

Volumn 162, Issue , 2015, Pages 369-376

  Cheng, Bao Hui ^a   Zhou, Xuelin ^a   Wang, Yan ^b   Chan, Judy Yuet Wa ^a   Lin, Huang Quan ^a   Or, Penelope M Y ^c   Wan, David Chi Cheong ^c   Leung, Ping Chung ^a   Fung, Kwok Pui ^a,c   Wang, Yi Fen ^d   Lau, Clara Bik San ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c Prince of Wales Hospital   (Hong Kong)

^d KUNMING INSTITUTE OF BOTANY   (China)

Author keywords

Anti HIV; Atazanavir; CYP3A2; Herb drug interaction; SH formula

Indexed keywords

ATAZANAVIR; CYTOCHROME P450 3A2; HERBACEOUS AGENT; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; KETOCONAZOLE; MIDAZOLAM; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CYP3A2 PROTEIN, RAT; CYTOCHROME P450 3A; DRUG COMBINATION; P16 PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1;

AREA UNDER THE CURVE; ARTICLE; CHINESE HERB; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; ENZYME INHIBITION; ENZYME INHIBITION ASSAY; HERB DRUG INTERACTION; IC50; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; RAT; ANIMAL; DRUG COMBINATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HIV INFECTIONS; HUMAN; METABOLISM; SPRAGUE DAWLEY RAT; THAILAND;

AMBYSTOMA TIGRINUM STEBBENSI VIRUS; ARTEMISIA CAPILLARIS; ASTRAGALUS MEMBRANACEUS; CARTHAMUS TINCTORIUS; GLYCYRRHIZA GLABRA; HUMAN IMMUNODEFICIENCY VIRUS 1; MORUS ALBA; RATTUS;

ANIMALS; ANTI-HIV AGENTS; ATAZANAVIR SULFATE; CYTOCHROME P-450 CYP3A; DRUG COMBINATIONS; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HERB-DRUG INTERACTIONS; HIV INFECTIONS; HIV PROTEASE; HUMANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; THAILAND;

EID: 84961291299     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.01.010     Document Type: Article

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