Cirrhosis and advanced fibrosis in Hispanics in Texas: The dominant contribution of central obesity

PLoS ONE

Volumn 11, Issue 3, 2016, Pages

  Jiao, Jingjing ^a   Watt, Gordon P ^b   Lee, Minjae ^c,d   Rahbar, Mohammad H ^b,c,d   Vatcheva, Kristina P ^b   Pan, Jen Jung ^c   McCormick, Joseph B ^b   Fisher Hoch, Susan P ^b   Fallon, Michael B ^c   Beretta, Laura ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ASPARTATE AMINOTRANSFERASE; ADIPONUTRIN, HUMAN; MEMBRANE PROTEIN; TRIACYLGLYCEROL LIPASE;

ABDOMINAL OBESITY; ADULT; AGE; AGED; ALCOHOL CONSUMPTION; ARTICLE; ATTRIBUTABLE RISK; CENTRAL OBESITY; CLINICAL ASSESSMENT; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DIABETES MELLITUS; FEMALE; GENETIC VARIABILITY; HEPATITIS C; HISPANIC; HUMAN; INCIDENCE; LIVER CIRRHOSIS; LIVER FIBROSIS; MALE; PREDICTION; PREVALENCE; PUBLIC HEALTH; RISK FACTOR; SEX DIFFERENCE; THROMBOCYTE; UNITED STATES; COMPLICATION; ETHNOLOGY; GENETICS; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICS AND NUMERICAL DATA; TEXAS;

COHORT STUDIES; FEMALE; HISPANIC AMERICANS; HUMANS; LIPASE; LIVER CIRRHOSIS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; OBESITY, ABDOMINAL; POLYMORPHISM, SINGLE NUCLEOTIDE; RESIDENCE CHARACTERISTICS; RISK FACTORS; TEXAS;

EID: 84961275841     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0150978     Document Type: Article

References (51)

1. Jiao J, Friedman SL, Aloman C. Hepatic fibrosis. Curr Opin Gastroenterol. 2009; 25(3):223-229. PMID: 19396960
2. Hernandez-Gea V, Friedman SL. Pathogenesis of liver fibrosis. Annual review of pathology. 2011; 6:425-456.doi: 10.1146/annurev-pathol-011110-130246 PMID: 21073339
3. Mokdad AA, Lopez AD, Shahraz S, Lozano R, Mokdad AH, Stanaway J, et al. Liver cirrhosis mortality in 187 countries between 1980 and 2010: A systematic analysis. BMC Med. 2014; 12(1):145.
4. Hernandez-Gea V, Toffanin S, Friedman SL, Llovet JM. Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma. Gastroenterology. 2013; 144(3):512-527.doi: 10. 1053/j.gastro.2013.01.002 PMID: 23313965
5. Schuppan D, Afdhal NH. Liver cirrhosis. Lancet. 2008; 371(9615):838-851.doi: 10.1016/S0140-6736 (08)60383-9 PMID: 18328931
6. Scaglione S, Kliethermes S, Cao G, Shoham D, Durazo R, Luke A, et al. The Epidemiology of Cirrhosis in the United States: A Population-based Study. J Clin Gastroenterol. 2015; 49(8):690-696.doi: 10. 1097/MCG.0000000000000208 PMID: 25291348
7. Koehler EM, Plompen EP, Schouten JN, Hansen BE, Darwish Murad S, Taimr P, et al. Presence of Diabetes Mellitus and Steatosis is Associated with Liver Stiffness in a General Population: The Rotterdam Study. Hepatology. 2015. Jul.15.doi: 10.1002/hep.27981
8. Sajja KC, Mohan DP, Rockey DC. Age and ethnicity in cirrhosis. Journal of investigative medicine: The official publication of the American Federation for Clinical Research. 2014; 62(7):920-926.
9. Heron M. Deaths: Leading causes for 2010. National vital statistics reports: From the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System. 2013; 62 (6):1-96.
10. Carrion AF, Ghanta R, Carrasquillo O, Martin P. Chronic liver disease in the Hispanic population of the United States. Clin Gastroenterol Hepatol. 2011; 9(10):834-841; quiz e109-10.doi: 10.1016/j.cgh. 2011.04.027 PMID: 21628000
11. Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity. Hepatology. 2004; 40 (6):1387-1395. PMID: 15565570
12. Weston SR, Leyden W, Murphy R, Bass NM, Bell BP, Manos MM, et al. Racial and ethnic distribution of nonalcoholic fatty liver in persons with newly diagnosed chronic liver disease. Hepatology. 2005; 41 (2):372-379. PMID: 15723436
13. Williams CD, Stengel J, Asike MI, Torres DM, Shaw J, Contreras M, et al. Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: A prospective study. Gastroenterology. 2011; 140(1):124-131.doi: 10. 1053/j.gastro.2010.09.038 PMID: 20858492
14. Romeo S, Kozlitina J, Xing C, Pertsemlidis A, Cox D, Pennacchio LA, et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet. 2008; 40(12):1461-1465.doi: 10.1038/ng.257 PMID: 18820647
15. Li Y, Xing C, Cohen JC, Hobbs HH. Genetic variant in PNPLA3 is associated with nonalcoholic fatty liver disease in China. Hepatology. 2012; 55(1):327-328.doi: 10.1002/hep.24659 PMID: 21898508
16. Xu R, Tao A, Zhang S, Deng Y, Chen G. Association between patatin-like phospholipase domain containing 3 gene (PNPLA3) polymorphisms and nonalcoholic fatty liver disease: A HuGE review and meta-analysis. Scientific reports. 2015; 5:9284.doi: 10.1038/srep09284 PMID: 25791171
17. Sookoian S, Pirola CJ. Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. Hepatology. 2011; 53(6):1883-1894.doi: 10.1002/hep.24283 PMID: 21381068
18. Li Q, Qu HQ, Rentfro AR, Grove ML, Mirza S, Lu Y, et al. PNPLA3 polymorphisms and liver aminotransferase levels in a Mexican American population. Clinical and investigative medicine Medecine clinique et experimentale. 2012; 35(4):E237-245. PMID: 22863562
19. Yuan X, Waterworth D, Perry JR, Lim N, Song K, Chambers JC, et al. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet. 2008; 83(4):520-528.doi: 10.1016/j.ajhg.2008.09.012 PMID: 18940312
20. Valenti L, Al-Serri A, Daly AK, Galmozzi E, Rametta R, Dongiovanni P, et al. Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology. 2010; 51(4):1209-1217.doi: 10.1002/hep.23622 PMID: 20373368
21. Tian C, Stokowski RP, Kershenobich D, Ballinger DG, Hinds DA. Variant in PNPLA3 is associated with alcoholic liver disease. Nat Genet. 2010; 42(1):21-23.doi: 10.1038/ng.488 PMID: 19946271
22. Trepo E, Gustot T, Degre D, Lemmers A, Verset L, Demetter P, et al. Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease. Journal of hepatology. 2011; 55(4):906-912.doi: 10.1016/j.jhep.2011.01.028 PMID: 21334404
23. Trepo E, Pradat P, Potthoff A, Momozawa Y, Quertinmont E, Gustot T, et al. Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C. Hepatology. 2011; 54(1):60-69.doi: 10.1002/hep.24350 PMID: 21488075
24. Huang CF, Dai CY, Yeh ML, Huang CI, Tai CM, Hsieh MH, et al. Association of diabetes and PNPLA3 genetic variants with disease severity of patients with chronic hepatitis C virus infection. Journal of hepatology. 2015; 62(3):512-518.doi: 10.1016/j.jhep.2014.10.011 PMID: 25457210
25. Shen JH, Li YL, Li D, Wang NN, Jing L, Huang YH. The rs738409 (I148M) variant of the PNPLA3 gene and cirrhosis: A meta-analysis. J Lipid Res. 2015; 56(1):167-175.doi: 10.1194/jlr.M048777 PMID: 25378656
26. Fisher-Hoch SP, Rentfro AR, Salinas JJ, Perez A, Brown HS, Reininger BM, et al. Socioeconomic status and prevalence of obesity and diabetes in a Mexican American community, Cameron County, Texas, 2004-2007. Preventing chronic disease. 2010; 7(3):A53. PMID: 20394692
27. Pan JJ, Qu HQ, Rentfro A, McCormick JB, Fisher-Hoch SP, Fallon MB. Prevalence of metabolic syndrome and risks of abnormal serum alanine aminotransferase in Hispanics: A population-based study. PLoS One. 2011; 6(6):e21515.doi: 10.1371/journal.pone.0021515 PMID: 21720553
28. Fisher-Hoch SP, Vatcheva KP, Rahbar MH, McCormick JB. Undiagnosed Diabetes and Pre-Diabetes in Health Disparities. PLoS One. 2015; 10(7):e0133135.doi: 10.1371/journal.pone.0133135 PMID: 26186342
29. Wai CT, Greenson JK, Fontana RJ, Kalbfleisch JD, Marrero JA, Conjeevaram HS, et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology. 2003; 38(2):518-526. PMID: 12883497
30. U.S. Department of Agriculture and U.S. Department of Health and Human Services. Diatery Guidelines for Americans. 2010. 7th edition. Available: Http://www.health.gov/dietaryguidelines/dga2010/dietaryguidelines2010.pdf.
31. Xiao G, Yang J, Yan L. Comparison of diagnostic accuracy of aspartate aminotransferase to platelet ratio index and fibrosis-4 index for detecting liver fibrosis in adult patients with chronic hepatitis B virus infection: A systemic review and meta-analysis. Hepatology. 2015; 61(1):292-302.doi: 10.1002/hep. 27382 PMID: 25132233
32. Lin ZH, Xin YN, Dong QJ, Wang Q, Jiang XJ, Zhan SH, et al. Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: An updated meta-analysis. Hepatology. 2011; 53(3):726-736.doi: 10.1002/hep.24105 PMID: 21319189
33. Novick DM, Enlow RW, Gelb AM, Stenger RJ, Fotino M, Winter JW, et al. Hepatic cirrhosis in young adults: Association with adolescent onset of alcohol and parenteral heroin abuse. Gut. 1985; 26(1):8-13. PMID: 3855296
34. Marzuillo P, Miraglia del Giudice E, Santoro N. Pediatric fatty liver disease: Role of ethnicity and genetics. World journal of gastroenterology: WJG. 2014; 20(23):7347-7355.doi: 10.3748/wjg.v20.i23.7347 PMID: 24966605
35. Feldstein AE, Charatcharoenwitthaya P, Treeprasertsuk S, Benson JT, Enders FB, Angulo P. The natural history of non-alcoholic fatty liver disease in children: A follow-up study for up to 20 years. Gut. 2009; 58(11):1538-1544.doi: 10.1136/gut.2008.171280 PMID: 19625277
36. Rentfro AR, Nino JC, Pones RM, Innis-Whitehouse W, Barroso CS, Rahbar MH, et al. Adiposity, biological markers of disease, and insulin resistance in Mexican American adolescents, 2004-2005. Preventing chronic disease. 2011; 8(2):A40. PMID: 21324254
37. Manco M, Bedogni G, Marcellini M, Devito R, Ciampalini P, Sartorelli MR, et al. Waist circumference correlates with liver fibrosis in children with non-alcoholic steatohepatitis. Gut. 2008; 57(9):1283-1287.doi: 10.1136/gut.2007.142919 PMID: 18218674
38. Van Der Poorten D, Milner KL, Hui J, Hodge A, Trenell MI, Kench JG, et al. Visceral fat: A key mediator of steatohepatitis in metabolic liver disease. Hepatology. 2008; 48(2):449-457.doi: 10.1002/hep. 22350 PMID: 18627003
39. Anstee QM, Day CP. The genetics of NAFLD. Nature reviews Gastroenterology & hepatology. 2013; 10(11):645-655.
40. Krawczyk M, Grunhage F, Zimmer V, Lammert F. Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: Non-invasive elastography-based study in chronic liver disease. Journal of hepatology. 2011; 55(2):299-306.doi: 10.1016/j.jhep.2010.10.042 PMID: 21168459
41. Liu YL, Reeves HL, Burt AD, Tiniakos D, McPherson S, Leathart JB, et al. TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease. Nature communications. 2014; 5:4309.doi: 10.1038/ncomms5309 PMID: 24978903
42. Marcolongo M, Young B, Dal Pero F, Fattovich G, Peraro L, Guido M, et al. A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C. Hepatology. 2009; 50(4):1038-1044.doi: 10.1002/hep.23111 PMID: 19676127
43. Huang H, Shiffman ML, Friedman S, Venkatesh R, Bzowej N, Abar OT, et al. A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C. Hepatology. 2007; 46(2):297-306. PMID: 17461418
44. Liu YL, Patman GL, Leathart JB, Piguet AC, Burt AD, Dufour JF, et al. Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma. Journal of hepatology. 2014; 61(1):75-81.doi: 10.1016/j.jhep.2014.02.030 PMID: 24607626
45. Trepo E, Guyot E, Ganne-Carrie N, Degre D, Gustot T, Franchimont D, et al. PNPLA3 (rs738409 C>G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis. Hepatology. 2012; 55(4):1307-1308.doi: 10.1002/hep.25518 PMID: 22162034
46. Nakaoka K, Hashimoto S, Kawabe N, Nitta Y, Murao M, Nakano T, et al. PNPLA3 I148M associations with liver carcinogenesis in Japanese chronic hepatitis C patients. SpringerPlus. 2015; 4:83.doi: 10. 1186/s40064-015-0870-5 PMID: 25713769
47. Trepo E, Nahon P, Bontempi G, Valenti L, Falleti E, Nischalke HD, et al. Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data. Hepatology. 2014; 59(6):2170-2177.doi: 10.1002/hep.26767 PMID: 24114809
48. Schlesinger S, Aleksandrova K, Pischon T, Fedirko V, Jenab M, Trepo E, et al. Abdominal obesity, weight gain during adulthood and risk of liver and biliary tract cancer in a European cohort. International journal of cancer Journal international du cancer. 2013; 132(3):645-657.doi: 10.1002/ijc.27645 PMID: 22618881
49. Albano JD, Ward E, Jemal A, Anderson R, Cokkinides VE, Murray T, et al. Cancer mortality in the United States by education level and race. J Natl Cancer Inst. 2007; 99(18):1384-1394. PMID: 17848670
50. Ramirez AG, Weiss NS, Holden AE, Suarez L, Cooper SP, Munoz E, et al. Incidence and risk factors for hepatocellular carcinoma in Texas Latinos: Implications for prevention research. PLoS One. 2012; 7 (4):e35573.doi: 10.1371/journal.pone.0035573 PMID: 22530052
51. Garza A, Vatcheva KP, Pan JJ, Rahbar MH, Fallon MB, McCormick JB, et al. Liver and Other Gastrointestinal Cancers Are Frequent in Mexican Americans. Journal of Racial and Ethnic Health Disparities. 2015 Mar. 28; doi: 10.1007/s40615-015-0104-0