Genetic variant in PNPLA3 is associated with nonalcoholic fatty liver disease in China

Hepatology

Volumn 55, Issue 1, 2012, Pages 327-328

  Li, Yiling ^a,b   Xing, Chao ^b   Cohen, Jonathan C ^b   Hobbs, Helen H ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; APOLIPOPROTEIN C3; ASPARTATE AMINOTRANSFERASE; GLUCOSE; LIVER PROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 3; PHOSPHOLIPASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CASE CONTROL STUDY; CHINA; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ECHOGRAPHY; FEMALE; GENE DOSAGE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HOSPITAL PATIENT; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; CHINA; FATTY LIVER; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; LIPASE; MALE; MEMBRANE PROTEINS; MIDDLE AGED;

EID: 84155174995     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24659     Document Type: Letter

References (5)

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2. Chitturi S, Wong VW, Farrell G. Nonalcoholic fatty liver in Asia: firmly entrenched and rapidly gaining ground. J Gastroenterol Hepatol 2011; 26(suppl 1): 163-172.
3. Fan JG, Peng YD. Metabolic syndrome and non-alcoholic fatty liver disease: Asian definitions and Asian studies. Hepatobiliary Pancreat Dis Int 2007; 6: 572-578.
4. Li X, Zhao Q, Wu K, Fan D. I148M variant of PNPLA3 confer increased risk for nonalcoholic fatty liver disease not only in European population, but also in Chinese population. HEPATOLOGY 2011; doi:10.1002/hep.24567.
5. Zeng MD, Fan JG, Lu LG, Li YM, Chen CW, Wang BY, et al. Guidelines for the diagnosis and treatment of nonalcoholic fatty liver diseases. J Dig Dis 2008; 9: 108-112.