Adenosine A1 Receptor Suppresses Tonic GABAA Receptor Currents in Hippocampal Pyramidal Cells and in a Defined Subpopulation of Interneurons

Cerebral Cortex

Volumn 26, Issue 3, 2016, Pages 1081-1095

  Rombo, Diogo M ^a,b   Dias, Raquel B ^a,b   Duarte, Sofia T ^a,b,c   Ribeiro, Joaquim A ^a,b   Lamsa, Karri P ^d   Sebastiaõ, Ana M ^a,b  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b UNIVERSITY OF LISBON   (Portugal)

^c HOSPITAL DONA ESTEFÂNIA   (Portugal)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Disinhibition; GABAergic interneurons; network excitability; neuromodulation; tonic and phasic inhibition

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR DELTA; ADENOSINE; ADENOSINE A1 RECEPTOR; CANNABINOID 1 RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; MUSCIMOL; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CELL SUBPOPULATION; CONTROLLED STUDY; ELECTROSTIMULATION; EVOKED RESPONSE; GABAERGIC TRANSMISSION; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; INTERNEURON; MALE; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; DRUG EFFECTS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; MINIATURE ENDPLATE POTENTIAL; NERVE CELL INHIBITION; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE; WISTAR RAT;

ANIMALS; CA1 REGION, HIPPOCAMPAL; CYCLIC AMP-DEPENDENT PROTEIN KINASES; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INHIBITORY POSTSYNAPTIC POTENTIALS; INTERNEURONS; MALE; MINIATURE POSTSYNAPTIC POTENTIALS; NEURAL INHIBITION; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C; PYRAMIDAL CELLS; RATS, WISTAR; RECEPTOR, ADENOSINE A1; RECEPTORS, GABA-A; TISSUE CULTURE TECHNIQUES;

EID: 84961275622     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhu288     Document Type: Article

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