Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Wheeler, Heather E ^a   Wing, Claudia ^a   Delaney, Shannon M ^a   Komatsu, Masaaki ^a   Dolan, M Eileen ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; HYDROXYUREA; PACLITAXEL; VINCRISTINE; ANTINEOPLASTIC AGENT; SMALL INTERFERING RNA; TUBULIN;

ARTICLE; BIOLOGICAL MODEL; CELL STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG INDUCED DISEASE; GENE; GENE EXPRESSION REGULATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MOLECULAR IMAGING; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL LESION; NERVE FIBER GROWTH; NEURAL STEM CELL; NEUROTOXICITY; PERIPHERAL NEUROPATHY; PHENOTYPE; PLURIPOTENT STEM CELL; TOXICOGENETICS; TUBB2A GENE; CELL LINE; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENE SILENCING; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; NERVE CELL; NEURITE;

ANTINEOPLASTIC AGENTS; CELL LINE; GENE EXPRESSION REGULATION; GENE SILENCING; HUMANS; INDUCED PLURIPOTENT STEM CELLS; NEURITES; NEURONS; PACLITAXEL; PHENOTYPE; RNA, SMALL INTERFERING; TUBULIN;

EID: 84923291367     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118020     Document Type: Article

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