MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency

Cell Stem Cell

Volumn 18, Issue 4, 2016, Pages 481-494

  Zhang, Hui ^a   Gayen, Srimonta ^a   Xiong, Jie ^a   Zhou, Bo ^a   Shanmugam, Avinash K ^a   Sun, Yuqing ^a   Karatas, Hacer ^b   Liu, Liu ^b   Rao, Rajesh C ^a   Wang, Shaomeng ^b   Nesvizhskii, Alexey I ^a   Kalantry, Sundeep ^a   Dou, Yali ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; HISTONE METHYLTRANSFERASE; METHYLTRANSFERASE INHIBITOR; MM 401; PROTEIN MLL1; TRANSCRIPTOME; UNCLASSIFIED DRUG; HISTONE LYSINE METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA PROTEIN; MLL PROTEIN, MOUSE; MM-401; MOLECULAR LIBRARY; OLIGOPEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CELL FATE; CELL TRANSFORMATION; CHIMERA; CONTROLLED STUDY; ECTODERM; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; GENE EXPRESSION; GENE REGULATORY NETWORK; GERM LINE; HISTONE METHYLATION; IN VITRO STUDY; MALE; MOUSE; MOUSE EMBRYONIC STEM CELL; NONHUMAN; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; UPREGULATION; X CHROMOSOME; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DEFICIENCY; DRUG EFFECTS; GERM LAYER; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY;

ANIMALS; CELL LINE; CELLULAR REPROGRAMMING; GERM LAYERS; HISTONE-LYSINE N-METHYLTRANSFERASE; MICE; MOUSE EMBRYONIC STEM CELLS; MYELOID-LYMPHOID LEUKEMIA PROTEIN; OLIGOPEPTIDES; PLURIPOTENT STEM CELLS; SMALL MOLECULE LIBRARIES;

EID: 84961231117     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.02.004     Document Type: Article

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