-
1
-
-
34648813720
-
ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
-
DAutreaux, B. & Toledano, M. B. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat. Rev. Mol. Cell Biol. 8, 813-824 (2007).
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 813-824
-
-
Dautreaux, B.1
Toledano, M.B.2
-
2
-
-
0034626735
-
Oxidants oxidative stress and the biology of ageing
-
Finkel, T. & Holbrook, N. J. Oxidants, oxidative stress and the biology of ageing. Nature 408, 239-247 (2000).
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
3
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman, D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11, 298-300 (1956).
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
4
-
-
84876926069
-
Mouse models of oxidative stress indicate a role for modulating healthy aging
-
Hamilton, R. T., Walsh, M. E. & Van Remmen, H. Mouse models of oxidative stress indicate a role for modulating healthy aging. J. Clin. Exp. Pathol. S4, 005 (2012).
-
(2012)
J. Clin. Exp. Pathol.
, vol.4
, pp. 005
-
-
Hamilton, R.T.1
Walsh, M.E.2
Van Remmen, H.3
-
5
-
-
84876917760
-
Thioredoxins glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: From cofactors to antioxidants to redox signaling
-
Hanschmann, E.-M., Godoy, J. R., Berndt, C., Hudemann, C. & Lillig, C. H. Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling. Antioxid. Redox Signal. 19, 1539-1605 (2013).
-
(2013)
Antioxid. Redox Signal.
, vol.19
, pp. 1539-1605
-
-
Hanschmann, E.-M.1
Godoy, J.R.2
Berndt, C.3
Hudemann, C.4
Lillig, C.H.5
-
6
-
-
0026470233
-
A mechanism for NADPH inhibition of catalase compound II formation
-
Hillar, A. & Nicholls, P. A mechanism for NADPH inhibition of catalase compound II formation. FEBS Lett. 314, 179-182 (1992).
-
(1992)
FEBS Lett.
, vol.314
, pp. 179-182
-
-
Hillar, A.1
Nicholls, P.2
-
7
-
-
37549026846
-
Glucose-6-phosphate dehydrogenase deficiency
-
Cappellini, M. D. & Fiorelli, G. Glucose-6-phosphate dehydrogenase deficiency. Lancet 371, 64-74 (2008).
-
(2008)
Lancet
, vol.371
, pp. 64-74
-
-
Cappellini, M.D.1
Fiorelli, G.2
-
8
-
-
84859787172
-
Glucose-6-phosphate dehydrogenase, NADPH, and cell survival
-
Stanton, R. C. Glucose-6-phosphate dehydrogenase, NADPH, and cell survival. IUBMB Life 64, 362-369 (2012).
-
(2012)
IUBMB Life
, vol.64
, pp. 362-369
-
-
Stanton, R.C.1
-
9
-
-
84880364889
-
Brain glucose-6-phosphate dehydrogenase protects against endogenous oxidative DNA damage and neurodegeneration in aged mice
-
Jeng, W., Loniewska, M. M. & Wells, P. G. Brain glucose-6-phosphate dehydrogenase protects against endogenous oxidative DNA damage and neurodegeneration in aged mice. ACS Chem Neurosci. 4, 1123-1132 (2013).
-
(2013)
ACS Chem Neurosci.
, vol.4
, pp. 1123-1132
-
-
Jeng, W.1
Loniewska, M.M.2
Wells, P.G.3
-
10
-
-
84938740158
-
Acute activation of oxidative pentose phosphate pathway as first-line response to oxidative stress in human skin cells
-
Kuehne, A., et al. Acute activation of oxidative pentose phosphate pathway as first-line response to oxidative stress in human skin cells. Mol. Cell 59, 359-371 (2015).
-
(2015)
Mol. Cell
, vol.59
, pp. 359-371
-
-
Kuehne, A.1
-
11
-
-
57749094923
-
Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster
-
Legan, S. K., et al. Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster. J. Biol. Chem. 283, 32492-32499 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 32492-32499
-
-
Legan, S.K.1
-
12
-
-
0030590373
-
High-level regulated expression of the human G6PD gene in transgenic mice
-
Corcoran, C. M., Fraser, P., Martini, G., Luzzatto, L. & Mason, P. J. High-level regulated expression of the human G6PD gene in transgenic mice. Gene 173, 241-246 (1996).
-
(1996)
Gene
, vol.173
, pp. 241-246
-
-
Corcoran, C.M.1
Fraser, P.2
Martini, G.3
Luzzatto, L.4
Mason, P.J.5
-
13
-
-
84876712745
-
Glucose-6-phosphate dehydrogenase deficiency: Disadvantages and possible benefits
-
Manganelli, G., Masullo, U., Passarelli, S. & Filosa, S. Glucose-6-phosphate dehydrogenase deficiency: disadvantages and possible benefits. Cardiovasc. Hematol. Disord. Drug Targets 13, 73-82 (2013).
-
(2013)
Cardiovasc. Hematol. Disord. Drug Targets
, vol.13
, pp. 73-82
-
-
Manganelli, G.1
Masullo, U.2
Passarelli, S.3
Filosa, S.4
-
14
-
-
37549068090
-
NAD/NADH and NADP/NADPH in cellular functions and cell death: Regulation and biological consequences
-
Ying, W. NAD/NADH and NADP/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid. Redox Signal. 10, 179-206 (2008).
-
(2008)
Antioxid. Redox Signal.
, vol.10
, pp. 179-206
-
-
Ying, W.1
-
15
-
-
0014082605
-
The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver
-
Williamson, D. H., Lund, P. & Krebs, H. A. The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem. J. 103, 514-527 (1967).
-
(1967)
Biochem. J.
, vol.103
, pp. 514-527
-
-
Williamson, D.H.1
Lund, P.2
Krebs, H.A.3
-
16
-
-
60849114962
-
A new G6PD knockdown tumor-cell line with reduced proliferation and increased susceptibility to oxidative stress
-
Li, D., et al. A new G6PD knockdown tumor-cell line with reduced proliferation and increased susceptibility to oxidative stress. Cancer Biother. Radiopharm. 24, 81-90 (2009).
-
(2009)
Cancer Biother. Radiopharm.
, vol.24
, pp. 81-90
-
-
Li, D.1
-
17
-
-
0032077942
-
Effects of G6PD overexpression in NIH3T3 cells treated with tert-butyl hydroperoxide or paraquat
-
Kuo, W. Y. & Tang, T. K. Effects of G6PD overexpression in NIH3T3 cells treated with tert-butyl hydroperoxide or paraquat. Free Radic. Biol. Med. 24, 1130-1138 (1998).
-
(1998)
Free Radic. Biol. Med.
, vol.24
, pp. 1130-1138
-
-
Kuo, W.Y.1
Tang, T.K.2
-
18
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn, S. E., Hull, R. L. & Utzschneider, K. M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444, 840-846 (2006).
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
19
-
-
83655191924
-
Overexpression of G6PD is associated with poor clinical outcome in gastric cancer
-
Wang, J., et al. Overexpression of G6PD is associated with poor clinical outcome in gastric cancer. Tumour Biol. 33, 95-101 (2012).
-
(2012)
Tumour Biol.
, vol.33
, pp. 95-101
-
-
Wang, J.1
-
20
-
-
84893484071
-
Glucose-6-phosphate dehydrogenase: A biomarker and potential therapeutic target for cancer
-
Zhang, C., Zhang, Z., Zhu, Y. & Qin, S. Glucose-6-phosphate dehydrogenase: a biomarker and potential therapeutic target for cancer. Anticancer Agents Med. Chem. 14, 280-289 (2014).
-
(2014)
Anticancer Agents Med. Chem.
, vol.14
, pp. 280-289
-
-
Zhang, C.1
Zhang, Z.2
Zhu, Y.3
Qin, S.4
-
21
-
-
79952280229
-
P53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
-
Jiang, P., et al. p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase. Nat. Cell Biol. 13, 310-316 (2011).
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 310-316
-
-
Jiang, P.1
-
22
-
-
0034107704
-
Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice
-
Kuo, W., Lin, J. & Tang, T. K. Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice. Int. J. Cancer 85, 857-864 (2000).
-
(2000)
Int. J. Cancer
, vol.85
, pp. 857-864
-
-
Kuo, W.1
Lin, J.2
Tang, T.K.3
-
23
-
-
77951878056
-
Induced pluripotent stem cells and senescence: Learning the biology to improve the technology
-
Banito, A. & Gil, J. Induced pluripotent stem cells and senescence: learning the biology to improve the technology. EMBO Rep. 11, 353-359 (2010).
-
(2010)
EMBO Rep.
, vol.11
, pp. 353-359
-
-
Banito, A.1
Gil, J.2
-
24
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
Jacks, T., et al. Tumor spectrum analysis in p53-mutant mice. Curr. Biol. 4, 1-7 (1994).
-
(1994)
Curr. Biol.
, vol.4
, pp. 1-7
-
-
Jacks, T.1
-
25
-
-
15844426692
-
Atm-deficient mice: A paradigm of ataxia telangiectasia
-
Barlow, C., et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 86, 159-171 (1996).
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
-
26
-
-
0026587657
-
Induction of mammary tumors by expression of polyomavirus middle T oncogene: A transgenic mouse model for metastatic disease
-
Guy, C. T., Cardiff, R. D. & Muller, W. J. Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol. Cell Biol. 12, 954-961 (1992).
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 954-961
-
-
Guy, C.T.1
Cardiff, R.D.2
Muller, W.J.3
-
27
-
-
0023854161
-
The e mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells
-
Harris, A. W., et al. The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells. J. Exp. Med. 167, 353-371 (1988).
-
(1988)
J. Exp. Med.
, vol.167
, pp. 353-371
-
-
Harris, A.W.1
-
28
-
-
0037112844
-
Super p53 mice exhibit enhanced DNA damage response, are tumor resistant and age normally
-
Garcia-Cao, I., et al. Super p53 mice exhibit enhanced DNA damage response, are tumor resistant and age normally. EMBO J. 21, 6225-6235 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 6225-6235
-
-
Garcia-Cao, I.1
-
29
-
-
8644284936
-
Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging
-
Matheu, A., et al. Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging. Genes Dev. 18, 2736-2746 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 2736-2746
-
-
Matheu, A.1
-
30
-
-
33745300235
-
Age-associated changes in oxidative damage and the activity of antioxidant enzymes in rats with inherited overgeneration of free radicals
-
Sinitsyna, O., et al. Age-associated changes in oxidative damage and the activity of antioxidant enzymes in rats with inherited overgeneration of free radicals. J. Cell. Mol. Med. 10, 206-215 (2006).
-
(2006)
J. Cell. Mol. Med.
, vol.10
, pp. 206-215
-
-
Sinitsyna, O.1
-
31
-
-
0035114063
-
Alterations of antioxidant enzymes and oxidative stress markers in aging
-
Kasapoglu, M. & Ozben, T. Alterations of antioxidant enzymes and oxidative stress markers in aging. Exp. Gerontol. 36, 209-220 (2001).
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 209-220
-
-
Kasapoglu, M.1
Ozben, T.2
-
32
-
-
0024341924
-
Modulation of hepatic glucose-6-phosphate dehydrogenase activity in male and female rats by estrogen
-
Ibim, S. E., Randall, R., Han, P. & Musey, P. I. Modulation of hepatic glucose-6-phosphate dehydrogenase activity in male and female rats by estrogen. Life Sci. 45, 1559-1565 (1989).
-
(1989)
Life Sci.
, vol.45
, pp. 1559-1565
-
-
Ibim, S.E.1
Randall, R.2
Han, P.3
Musey, P.I.4
-
33
-
-
84901019405
-
Estradiol promotes pentose phosphate pathway addiction and cell survival via reactivation of Akt in mTORC1 hyperactive cells
-
Sun, Y., et al. Estradiol promotes pentose phosphate pathway addiction and cell survival via reactivation of Akt in mTORC1 hyperactive cells. Cell Death Dis. 5, e1231 (2014).
-
(2014)
Cell Death Dis.
, vol.5
, pp. e1231
-
-
Sun, Y.1
-
34
-
-
62249096975
-
Glutathione dysregulation and the etiology and progression of human diseases
-
Ballatori, N., et al. Glutathione dysregulation and the etiology and progression of human diseases. Biol. Chem. 390, 191-214 (2009).
-
(2009)
Biol. Chem.
, vol.390
, pp. 191-214
-
-
Ballatori, N.1
-
35
-
-
69349103956
-
The Ink4/Arf locus is a barrier for iPS cell reprogramming
-
Li, H., et al. The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 460, 1136-1139 (2009).
-
(2009)
Nature
, vol.460
, pp. 1136-1139
-
-
Li, H.1
-
36
-
-
34250922204
-
And absence of glucose-6-phosphate dehydrogenase in erythrocytes; An enzyme abnormality of erythrocytes
-
Waller, H. D., Lohr, G. W. & Tabatabai, M. Hemolysis and absence of glucose-6-phosphate dehydrogenase in erythrocytes; an enzyme abnormality of erythrocytes. Klin. Wochenschr. 35, 1022-1027 (1957).
-
(1957)
Klin. Wochenschr.
, vol.35
, pp. 1022-1027
-
-
Waller, H.D.1
Lohr, G.W.2
Hemolysis, T.M.3
-
37
-
-
0025601459
-
Anomeric preference of glucose utilization in human erythrocytes loaded with glucokinase
-
Miwa, I., Fukatsu, H., Toyoda, Y. & Okuda, J. Anomeric preference of glucose utilization in human erythrocytes loaded with glucokinase. Biochem. Biophys. Res. Commun. 173, 201-207 (1990).
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 201-207
-
-
Miwa, I.1
Fukatsu, H.2
Toyoda, Y.3
Okuda, J.4
-
38
-
-
84922251261
-
Growth hormone replacement therapy prevents sarcopenia by a dual mechanism: Improvement of protein balance and of antioxidant defenses
-
Brioche, T., et al. Growth hormone replacement therapy prevents sarcopenia by a dual mechanism: improvement of protein balance and of antioxidant defenses. J. Gerontol. A. Biol. Sci. Med. Sci. 69, 1186-1198 (2014).
-
(2014)
J. Gerontol. A. Biol. Sci. Med. Sci.
, vol.69
, pp. 1186-1198
-
-
Brioche, T.1
-
39
-
-
0023201142
-
Lipoperoxides in plasma as measured by liquidchromatographic separation of malondialdehyde-thiobarbituric acid adduct
-
Wong, S. H., et al. Lipoperoxides in plasma as measured by liquidchromatographic separation of malondialdehyde-thiobarbituric acid adduct. Clin. Chem. 33, 214-220 (1987).
-
(1987)
Clin. Chem.
, vol.33
, pp. 214-220
-
-
Wong, S.H.1
-
40
-
-
77953538684
-
Xanthine oxidase-induced oxidative stress causes activation of NF-kappaB and inflammation in the liver of type i diabetic rats
-
Romagnoli, M., et al. Xanthine oxidase-induced oxidative stress causes activation of NF-kappaB and inflammation in the liver of type I diabetic rats. Free Radic. Biol. Med. 49, 171-177 (2010).
-
(2010)
Free Radic. Biol. Med.
, vol.49
, pp. 171-177
-
-
Romagnoli, M.1
-
41
-
-
23844540597
-
Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats
-
Gomez-Cabrera, M.-C., et al. Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats. J. Physiol. 567, 113-120 (2005).
-
(2005)
J. Physiol.
, vol.567
, pp. 113-120
-
-
Gomez-Cabrera, M.-C.1
|