메뉴 건너뛰기




Volumn 91, Issue , 2016, Pages 37-46

Omega-3 polyunsaturated fatty acids mitigate blood-brain barrier disruption after hypoxic-ischemic brain injury

Author keywords

Blood brain barrier; Hypoxia ischemia; MMP 2; MMP 9; Tight junction

Indexed keywords

GELATINASE A; GELATINASE B; IMMUNOGLOBULIN G; MATRIX METALLOPROTEINASE; OMEGA 3 FATTY ACID; TIGHT JUNCTION PROTEIN;

EID: 84960899333     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2016.02.020     Document Type: Article
Times cited : (71)

References (42)
  • 1
    • 83655197527 scopus 로고    scopus 로고
    • Increased MMP-9 and TIMP-1 in mouse neonatal brain and plasma and in human neonatal plasma after hypoxia-ischemia: a potential marker of neonatal encephalopathy
    • Bednarek N., et al. Increased MMP-9 and TIMP-1 in mouse neonatal brain and plasma and in human neonatal plasma after hypoxia-ischemia: a potential marker of neonatal encephalopathy. Pediatr. Res. 2012, 71:63-70.
    • (2012) Pediatr. Res. , vol.71 , pp. 63-70
    • Bednarek, N.1
  • 2
    • 84887610342 scopus 로고    scopus 로고
    • Docosahexaenoic acid reduces cellular inflammatory response following permanent focal cerebral ischemia in rats
    • Chang C.Y., et al. Docosahexaenoic acid reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. J. Nutr. Biochem. 2013, 24:2127-2137.
    • (2013) J. Nutr. Biochem. , vol.24 , pp. 2127-2137
    • Chang, C.Y.1
  • 3
    • 70349904406 scopus 로고    scopus 로고
    • Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain
    • Chen W., et al. Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain. J. Neurochem. 2009, 111:726-736.
    • (2009) J. Neurochem. , vol.111 , pp. 726-736
    • Chen, W.1
  • 4
    • 84927645086 scopus 로고    scopus 로고
    • N-3 PUFA supplementation benefits microglial responses to myelin pathology
    • Chen S., et al. n-3 PUFA supplementation benefits microglial responses to myelin pathology. Sci. Rep. 2014, 4:7458.
    • (2014) Sci. Rep. , vol.4 , pp. 7458
    • Chen, S.1
  • 5
    • 79960755029 scopus 로고    scopus 로고
    • Tight junctions in brain barriers during central nervous system inflammation
    • Coisne C., Engelhardt B. Tight junctions in brain barriers during central nervous system inflammation. Antioxid. Redox. Signal. 2011, 15:1285-1303.
    • (2011) Antioxid. Redox. Signal. , vol.15 , pp. 1285-1303
    • Coisne, C.1    Engelhardt, B.2
  • 6
    • 30844472909 scopus 로고    scopus 로고
    • IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor
    • Deane R., et al. IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor. J. Neurosci. 2005, 25:11495-11503.
    • (2005) J. Neurosci. , vol.25 , pp. 11495-11503
    • Deane, R.1
  • 7
    • 84928827084 scopus 로고    scopus 로고
    • Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia
    • Ek C.J., et al. Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia. J. Cereb. Blood Flow Metab. 2015, 35:818-827.
    • (2015) J. Cereb. Blood Flow Metab. , vol.35 , pp. 818-827
    • Ek, C.J.1
  • 8
    • 84863661984 scopus 로고    scopus 로고
    • Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat
    • Fernandez-Lopez D., et al. Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat. J Neurosci. 2012, 32:9588-9600.
    • (2012) J Neurosci. , vol.32 , pp. 9588-9600
    • Fernandez-Lopez, D.1
  • 9
    • 23744437416 scopus 로고    scopus 로고
    • Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia
    • Gidday J.M., et al. Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia. Am. J. Physiol. Heart. Circ. Physiol. 2005, 289:H558-H568.
    • (2005) Am. J. Physiol. Heart. Circ. Physiol. , vol.289 , pp. H558-H568
    • Gidday, J.M.1
  • 10
    • 0035805530 scopus 로고    scopus 로고
    • The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism
    • Hahn-Dantona E., et al. The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism. J Biol Chem. 2001, 276:15498-15503.
    • (2001) J Biol Chem. , vol.276 , pp. 15498-15503
    • Hahn-Dantona, E.1
  • 11
    • 84896711281 scopus 로고    scopus 로고
    • Docosahexaenoic acid confers enduring neuroprotection in experimental stroke
    • Hong S.H., et al. Docosahexaenoic acid confers enduring neuroprotection in experimental stroke. J. Neurol. Sci. 2014, 338:135-141.
    • (2014) J. Neurol. Sci. , vol.338 , pp. 135-141
    • Hong, S.H.1
  • 12
    • 84988694076 scopus 로고    scopus 로고
    • Docosahexaenoic acid improves behavior and attenuates blood-brain barrier injury induced by focal cerebral ischemia in rats
    • Hong S.H., et al. Docosahexaenoic acid improves behavior and attenuates blood-brain barrier injury induced by focal cerebral ischemia in rats. Exp. Transl. Stroke. Med. 2015, 7:3.
    • (2015) Exp. Transl. Stroke. Med. , vol.7 , pp. 3
    • Hong, S.H.1
  • 13
    • 0023147380 scopus 로고
    • Home testing of urine chloride to estimate dietary sodium intake: evaluation of feasibility and accuracy
    • Jeffery R.W., et al. Home testing of urine chloride to estimate dietary sodium intake: evaluation of feasibility and accuracy. Addict. Behav. 1987, 12:17-21.
    • (1987) Addict. Behav. , vol.12 , pp. 17-21
    • Jeffery, R.W.1
  • 14
    • 77952513645 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: role of inflammatory cells
    • Jin R., et al. Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J. Leukoc. Biol. 2010, 87:779-789.
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 779-789
    • Jin, R.1
  • 15
    • 84922337429 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown involves four distinct stages of vascular damage in various models of experimental focal cerebral ischemia
    • Krueger M., et al. Blood-brain barrier breakdown involves four distinct stages of vascular damage in various models of experimental focal cerebral ischemia. J. Cereb. Blood Flow Metab. 2015, 35:292-303.
    • (2015) J. Cereb. Blood Flow Metab. , vol.35 , pp. 292-303
    • Krueger, M.1
  • 16
    • 84897845208 scopus 로고    scopus 로고
    • Interleukin-1beta induces an inflammatory response and the breakdown of the endothelial cell layer in an improved human THBMEC-based in vitro blood-brain barrier model
    • Labus J., et al. Interleukin-1beta induces an inflammatory response and the breakdown of the endothelial cell layer in an improved human THBMEC-based in vitro blood-brain barrier model. J. Neurosci. Methods 2014, 228:35-45.
    • (2014) J. Neurosci. Methods , vol.228 , pp. 35-45
    • Labus, J.1
  • 17
    • 84891547893 scopus 로고    scopus 로고
    • Adoptive regulatory T-cell therapy protects against cerebral ischemia
    • Li P., et al. Adoptive regulatory T-cell therapy protects against cerebral ischemia. Ann. Neurol. 2013, 74:458-471.
    • (2013) Ann. Neurol. , vol.74 , pp. 458-471
    • Li, P.1
  • 18
    • 84889258454 scopus 로고    scopus 로고
    • Adoptive regulatory T-cell therapy preserves systemic immune homeostasis after cerebral ischemia
    • Li P., et al. Adoptive regulatory T-cell therapy preserves systemic immune homeostasis after cerebral ischemia. Stroke 2013, 44:3509-3515.
    • (2013) Stroke , vol.44 , pp. 3509-3515
    • Li, P.1
  • 19
    • 35848933695 scopus 로고    scopus 로고
    • Inhibitory effect of polyunsaturated fatty acids on MMP-9 release from microglial cells - implications for complementary multiple sclerosis treatment
    • Liuzzi G.M., et al. Inhibitory effect of polyunsaturated fatty acids on MMP-9 release from microglial cells - implications for complementary multiple sclerosis treatment. Neurochem. Res. 2007, 32:2184-2193.
    • (2007) Neurochem. Res. , vol.32 , pp. 2184-2193
    • Liuzzi, G.M.1
  • 20
    • 67649452508 scopus 로고    scopus 로고
    • Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat
    • Maddahi A., et al. Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat. BMC Neurosci. 2009, 10:56.
    • (2009) BMC Neurosci. , vol.10 , pp. 56
    • Maddahi, A.1
  • 21
    • 58149357031 scopus 로고    scopus 로고
    • Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice
    • McColl B.W., et al. Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice. J. Neurosci. 2008, 28:9451-9462.
    • (2008) J. Neurosci. , vol.28 , pp. 9451-9462
    • McColl, B.W.1
  • 22
    • 84924410989 scopus 로고    scopus 로고
    • Blood-brain barrier dysfunction in disorders of the developing brain
    • Moretti R., et al. Blood-brain barrier dysfunction in disorders of the developing brain. Front. Neurosci. 2015, 9:40.
    • (2015) Front. Neurosci. , vol.9 , pp. 40
    • Moretti, R.1
  • 23
    • 0030665117 scopus 로고    scopus 로고
    • Vulnerability to cerebral hypoxic-ischemic insult in neonatal but not in adult rats is in parallel with disruption of the blood-brain barrier
    • discussion 2288-9
    • Muramatsu K., et al. Vulnerability to cerebral hypoxic-ischemic insult in neonatal but not in adult rats is in parallel with disruption of the blood-brain barrier. Stroke 1997, 28:2281-2288. discussion 2288-9.
    • (1997) Stroke , vol.28 , pp. 2281-2288
    • Muramatsu, K.1
  • 24
    • 84908375551 scopus 로고    scopus 로고
    • The pivotal role of astrocytes in an in vitro stroke model of the blood-brain barrier
    • Neuhaus W., et al. The pivotal role of astrocytes in an in vitro stroke model of the blood-brain barrier. Front. Cell. Neurosci. 2014, 8:352.
    • (2014) Front. Cell. Neurosci. , vol.8 , pp. 352
    • Neuhaus, W.1
  • 25
    • 0028106384 scopus 로고
    • Inhibition by n-3 fatty acids of arachidonic acid metabolism in a primary culture of astroglial cells
    • Petroni A., et al. Inhibition by n-3 fatty acids of arachidonic acid metabolism in a primary culture of astroglial cells. Neurochem. Res. 1994, 19:1187-1193.
    • (1994) Neurochem. Res. , vol.19 , pp. 1187-1193
    • Petroni, A.1
  • 26
    • 84865642422 scopus 로고    scopus 로고
    • Interaction between intravenous immunoglobulin (IVIg) and the low-density lipoprotein receptor-related protein 1: a role for transcytosis across the blood brain barrier?
    • Proulx D.P., et al. Interaction between intravenous immunoglobulin (IVIg) and the low-density lipoprotein receptor-related protein 1: a role for transcytosis across the blood brain barrier?. J. Neuroimmunol. 2012, 251:39-44.
    • (2012) J. Neuroimmunol. , vol.251 , pp. 39-44
    • Proulx, D.P.1
  • 27
    • 84888203676 scopus 로고    scopus 로고
    • Hypoxia induces metalloproteinase-9 activation and human vascular smooth muscle cell migration through low-density lipoprotein receptor-related protein 1-mediated Pyk2 phosphorylation
    • Revuelta-Lopez E., et al. Hypoxia induces metalloproteinase-9 activation and human vascular smooth muscle cell migration through low-density lipoprotein receptor-related protein 1-mediated Pyk2 phosphorylation. Arterioscler. Thromb. Vasc. Biol. 2013, 33:2877-2887.
    • (2013) Arterioscler. Thromb. Vasc. Biol. , vol.33 , pp. 2877-2887
    • Revuelta-Lopez, E.1
  • 28
    • 1042301387 scopus 로고    scopus 로고
    • The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells
    • Rozanov D.V., et al. The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells. J Biol Chem. 2004, 279:4260-4268.
    • (2004) J Biol Chem. , vol.279 , pp. 4260-4268
    • Rozanov, D.V.1
  • 29
    • 61849109389 scopus 로고    scopus 로고
    • Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis
    • Shinto L., et al. Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis. Prostaglandins Leukot Essent Fatty Acids. 2009, 80:131-136.
    • (2009) Prostaglandins Leukot Essent Fatty Acids. , vol.80 , pp. 131-136
    • Shinto, L.1
  • 30
    • 84856539330 scopus 로고    scopus 로고
    • The effects of omega-3 fatty acids on matrix metalloproteinase-9 production and cell migration in human immune cells: implications for multiple sclerosis
    • Shinto L., et al. The effects of omega-3 fatty acids on matrix metalloproteinase-9 production and cell migration in human immune cells: implications for multiple sclerosis. Autoimmune Dis. 2011, 2011:134592.
    • (2011) Autoimmune Dis. , vol.2011 , pp. 134592
    • Shinto, L.1
  • 31
    • 59149098234 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9
    • Song H., et al. Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. Cancer Res. 2009, 69:879-886.
    • (2009) Cancer Res. , vol.69 , pp. 879-886
    • Song, H.1
  • 32
    • 84880603582 scopus 로고    scopus 로고
    • Therapeutic hypothermia in neonatal hypoxic ischemic encephalopathy: electrographic seizures and magnetic resonance imaging evidence of injury
    • Srinivasakumar P., et al. Therapeutic hypothermia in neonatal hypoxic ischemic encephalopathy: electrographic seizures and magnetic resonance imaging evidence of injury. J. Pediatr. 2013, 163:465-470.
    • (2013) J. Pediatr. , vol.163 , pp. 465-470
    • Srinivasakumar, P.1
  • 33
    • 0142139279 scopus 로고    scopus 로고
    • Emerging features in the regulation of MMP-9 gene expression for the development of novel molecular targets and therapeutic strategies
    • St-Pierre Y., et al. Emerging features in the regulation of MMP-9 gene expression for the development of novel molecular targets and therapeutic strategies. Curr. Drug Targets Inflamm. Allergy. 2003, 2:206-215.
    • (2003) Curr. Drug Targets Inflamm. Allergy. , vol.2 , pp. 206-215
    • St-Pierre, Y.1
  • 34
    • 33847092562 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 gene knock-out protects the immature brain after cerebral hypoxia-ischemia
    • Svedin P., et al. Matrix metalloproteinase-9 gene knock-out protects the immature brain after cerebral hypoxia-ischemia. J. Neurosci. 2007, 27:1511-1518.
    • (2007) J. Neurosci. , vol.27 , pp. 1511-1518
    • Svedin, P.1
  • 35
    • 84901034821 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke
    • Wang J., et al. Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke. Neurobiol. Dis. 2014, 68:91-103.
    • (2014) Neurobiol. Dis. , vol.68 , pp. 91-103
    • Wang, J.1
  • 36
    • 84941314137 scopus 로고    scopus 로고
    • Matrix metalloproteinases as therapeutic targets for stroke
    • Yang Y., Rosenberg G.A. Matrix metalloproteinases as therapeutic targets for stroke. Brain Res. 2015.
    • (2015) Brain Res.
    • Yang, Y.1    Rosenberg, G.A.2
  • 37
    • 84880331059 scopus 로고    scopus 로고
    • Early inhibition of MMP activity in ischemic rat brain promotes expression of tight junction proteins and angiogenesis during recovery
    • Yang Y., et al. Early inhibition of MMP activity in ischemic rat brain promotes expression of tight junction proteins and angiogenesis during recovery. J. Cereb. Blood Flow Metab. 2013, 33:1104-1114.
    • (2013) J. Cereb. Blood Flow Metab. , vol.33 , pp. 1104-1114
    • Yang, Y.1
  • 38
    • 0035283233 scopus 로고    scopus 로고
    • Mediated efflux of IgG molecules from brain to blood across the blood-brain barrier
    • Zhang Y., Pardridge W.M. Mediated efflux of IgG molecules from brain to blood across the blood-brain barrier. J. Neuroimmunol. 2001, 114:168-172.
    • (2001) J. Neuroimmunol. , vol.114 , pp. 168-172
    • Zhang, Y.1    Pardridge, W.M.2
  • 39
    • 77957983889 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acid supplementation confers long-term neuroprotection against neonatal hypoxic-ischemic brain injury through anti-inflammatory actions
    • Zhang W., et al. Omega-3 polyunsaturated fatty acid supplementation confers long-term neuroprotection against neonatal hypoxic-ischemic brain injury through anti-inflammatory actions. Stroke 2010, 41:2341-2347.
    • (2010) Stroke , vol.41 , pp. 2341-2347
    • Zhang, W.1
  • 40
    • 84893122611 scopus 로고    scopus 로고
    • Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1
    • Zhang M., et al. Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1. J. Neurosci. 2014, 34:1903-1915.
    • (2014) J. Neurosci. , vol.34 , pp. 1903-1915
    • Zhang, M.1
  • 41
    • 84945489185 scopus 로고    scopus 로고
    • Dietary supplementation with omega-3 polyunsaturated fatty acids robustly promotes neurovascular restorative dynamics and improves neurological functions after stroke
    • Zhang W., et al. Dietary supplementation with omega-3 polyunsaturated fatty acids robustly promotes neurovascular restorative dynamics and improves neurological functions after stroke. Exp. Neurol. 2015, 272:170-180.
    • (2015) Exp. Neurol. , vol.272 , pp. 170-180
    • Zhang, W.1
  • 42
    • 12844260177 scopus 로고    scopus 로고
    • Eicosapentaenoic acid prevents lipopolysaccharide-stimulated DNA binding of activator protein-1 and c-Jun N-terminal kinase activity
    • Zhao Y., Chen L.H. Eicosapentaenoic acid prevents lipopolysaccharide-stimulated DNA binding of activator protein-1 and c-Jun N-terminal kinase activity. J. Nutr. Biochem. 2005, 16:78-84.
    • (2005) J. Nutr. Biochem. , vol.16 , pp. 78-84
    • Zhao, Y.1    Chen, L.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.