Safety, immunogenicity, and protective efficacy of intradermal immunization with aseptic, purified, cryopreserved plasmodium falciparum sporozoites in volunteers under chloroquine prophylaxis: A randomized controlled trial

American Journal of Tropical Medicine and Hygiene

Volumn 94, Issue 3, 2016, Pages 663-673

  Bastiaens, Guido J H ^a   Van Meer, Maurits P A ^b   Scholzen, Anja ^a   Obiero, Joshua M ^c   Vatanshenassan, Mansoureh ^d   Van Grinsven, Tim ^a   Lee Sim, B Kim ^e   Billingsley, Peter F ^e   James, Eric R ^e   Gunasekera, Anusha ^e   Bijker, Else M ^a   Van Gemert, Geert Jan ^a   Van De Vegte Bolmer, Marga ^a   Graumans, Wouter ^a   Hermsen, Cornelus C ^a   De Mast, Quirijn ^a   Van Der Ven, André J A M ^a   Hoffman, Stephen L ^e   Sauerwein, Robert W ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CBS KNAW FUNGAL BIODIVERSITY CENTRE   (Netherlands)

^e SANARIA INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; SODIUM CHLORIDE; SPOROZOITE VACCINE; ANTIMALARIAL AGENT;

ABDOMINAL PAIN; ADULT; ALLERGIC REACTION; ANTIBODY TITER; ARTICLE; BLOOD SMEAR; CELLULAR IMMUNITY; CHEMOPROPHYLAXIS; CHILL; COMPARATIVE STUDY; CONTROLLED STUDY; DIARRHEA; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG SAFETY; FATIGUE; FEMALE; FEVER; HEADACHE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; LIMIT OF DETECTION; MALAISE; MALE; MICROSCOPY; MOSQUITO BITE; MYALGIA; NAUSEA; NORMAL HUMAN; PARASITEMIA; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDY; TETANUS PROPHYLAXIS; THORAX PAIN; URTICARIA; VOMITING; ADOLESCENT; ANIMAL; ANOPHELES; CRYOPRESERVATION; IMMUNOLOGY; INSECT BITE; INTRADERMAL DRUG ADMINISTRATION; MALARIA, FALCIPARUM; PARASITOLOGY; PATIENT SAFETY; PHYSIOLOGY; PLASMODIUM FALCIPARUM; SPOROZOITE; YOUNG ADULT;

ADOLESCENT; ADULT; ANIMALS; ANOPHELES; ANTIMALARIALS; CHLOROQUINE; CRYOPRESERVATION; DOUBLE-BLIND METHOD; HUMANS; IMMUNIZATION; INJECTIONS, INTRADERMAL; INSECT BITES AND STINGS; MALARIA, FALCIPARUM; MALE; PATIENT SAFETY; PLASMODIUM FALCIPARUM; SPOROZOITES; YOUNG ADULT;

EID: 84960887513     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.15-0621     Document Type: Article

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