Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved plasmodium falciparum sporozoites

American Journal of Tropical Medicine and Hygiene

Volumn 91, Issue 3, 2014, Pages 471-480

  Shekalaghe, Seif ^a   Rutaihwa, Mastidia ^a   Billingsley, Peter F ^b   Chemba, Mwajuma ^a   Daubenberger, Claudia A ^c,d   James, Eric R ^b   Mpina, Maximillian ^a,c,d   Juma, Omar Ali ^a   Schindler, Tobias ^c,d   Huber, Eric ^c   Gunasekera, Anusha ^b   Manoj, Anita ^b   Simon, Beatus ^a   Saverino, Elizabeth ^b   Church, L W Preston ^e   Hermsen, Cornelus C ^f   Sauerwein, Robert W ^f   Plowe, Christopher ^g   Venkatesan, Meera ^g   Sasi, Philip ^h   Lweno, Omar ^a   Mutani, Paul ^a   Hamad, Ali ^a   Mohammed, Ali ^a   Urassa, Alwisa ^a   Mzee, Tutu ^a   Padilla, Debbie ^b   Ruben, Adam ^b   Sim, B Kim Lee ^b   Tanner, Marcel ^c,d   Abdulla, Salim ^a   Hoffman, Stephen L ^b   more..

^a IFAKARA HEALTH INSTITUTE   (Tanzania)

^b SANARIA INC   (United States)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^d UNIVERSITY OF BASEL   (Switzerland)

^e RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^h MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ARTEMETHER PLUS BENFLUMETOL; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CREATININE; GLUCOSE; HEMOGLOBIN; MALARIA VACCINE; SODIUM CHLORIDE; SPOROZOITE VACCINE; SUBUNIT VACCINE;

ABNORMAL LABORATORY RESULT; ACUTE DISEASE; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALPHA THALASSEMIA; ANTIMICROBIAL THERAPY; ARTHRALGIA; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AXILLA TEMPERATURE; BILIRUBIN BLOOD LEVEL; BLOOD SMEAR; CAPILLARY ELECTROPHORESIS; CLINICAL ARTICLE; CONTROLLED HUMAN MALARIA INFECTION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRYOPRESERVATION; DRUG HYPERSENSITIVITY; DRUG INDUCED HEADACHE; DRUG PURIFICATION; DRUG SAFETY; DRUG TOLERABILITY; DYSENTERY; FATIGUE; FOLLOW UP; GASTROENTERITIS; GLUCOSE BLOOD LEVEL; HEART INJURY; HUMAN; INCIDENCE; INOCULATION; LEUKOCYTE COUNT; MALAISE; MALARIA; MALARIA CONTROL; MALE; MOSQUITO BITE; MULTIPLEX POLYMERASE CHAIN REACTION; PARASITEMIA; PLASMODIUM FALCIPARUM; RANDOMIZED CONTROLLED TRIAL; SPOROZOITE; SYSTEMIC DISEASE; TANZANIAN; THROMBOCYTE COUNT; VACCINATION; YOUNG ADULT; ANIMAL; CLASSIFICATION; CONTROLLED CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; GENETICS; GENOTYPE; IMMUNOLOGY; INTRADERMAL DRUG ADMINISTRATION; MALARIA FALCIPARUM; PARASITOLOGY; TANZANIA;

PLASMODIUM FALCIPARUM;

ADULT; ALPHA-THALASSEMIA; ANIMALS; CRYOPRESERVATION; DOUBLE-BLIND METHOD; GENOTYPE; HUMANS; INJECTIONS, INTRADERMAL; MALARIA VACCINES; MALARIA, FALCIPARUM; MALE; PARASITEMIA; PLASMODIUM FALCIPARUM; SPOROZOITES; TANZANIA; YOUNG ADULT;

EID: 84907012077     PISSN: 00029637     EISSN: 14761645     Source Type: Journal    
DOI: 10.4269/ajtmh.14-0119     Document Type: Article

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